Enhancement of Combined Umami and Salty Taste by Glutathione in the Human Tongue and Brain.

abstract：:Three experiments assessed potential changes in the rat's perception of sodium chloride (NaCl) during a state of sodium appetite. In Experiment 1, sodium-sufficient rats licking a range of NaCl concentrations (0.028-0.89M) in 15s trials showed an inverted U-shaped concentration response function peaking at 0.281M. Dep...

journal_title：Chemical senses

authors： St John SJ

更新日期：2017-02-01 00:00:00

abstract：:Suppression of the saltiness of NaCl solutions by amiloride, a sodium channel blocker, has previously been reported a number of times in humans. This suppression was seen with techniques that involved stimulation of small areas of the tongue. It was not certain, however, whether amiloride would suppress saltiness with...

journal_title：Chemical senses

authors： Tennissen AM,McCutcheon NB

更新日期：1996-04-01 00:00:00

abstract：:The role of Ca(2+) in insect olfactory transduction was studied in the moth Spodoptera littoralis. Single sensillum recordings were made to investigate in vivo the role of sensillar Ca(2+) on the electrophysiological properties of sex pheromone responsive olfactory receptor neurons (ORNs). Lowering the sensillar Ca(2+...

journal_title：Chemical senses

authors： Pézier A,Acquistapace A,Renou M,Rospars JP,Lucas P

更新日期：2007-05-01 00:00:00

abstract：:Despite long and intense research, some fundamental questions regarding representation of taste information in the brain still remain unanswered. This might in part be due to shortcomings of the established methods that limit the researcher either to thorough characterization of few elements or to analyze the response...

journal_title：Chemical senses

authors： Töle J,Stolzenburg A,Tyree SM,Stähler F,Meyerhof W

更新日期：2018-04-23 00:00:00

abstract：:The effects of Triton X-100 on the olfactory epithelium (OE) of adult zebrafish were examined to study neuronal turnover in this model system. Fish were killed at various time points after detergent application and stained with hematoxylin and eosin to examine olfactory structures, immunocytochemistry to examine cell ...

journal_title：Chemical senses

authors： Iqbal T,Byrd-Jacobs C

更新日期：2010-06-01 00:00:00

abstract：:Hyperosmia is suspected in pregnancy; however, no empirical study using validated measures of olfactory function has clearly confirmed the anecdotal reports of this phenomenon. The goal of the current study is to compare the olfactory sensitivity of pregnant women to that of nonpregnant women and men. All participants...

journal_title：Chemical senses

authors： Cameron EL

更新日期：2014-02-01 00:00:00

abstract：:The present study analyzed 42 organic solvent extracts of scent mark pools from five dominant female common marmosets by gas chromatography (GC) and combined GC and mass spectrometry. We determined whether there were qualitative or quantitative differences between the chemical composition of scent marks from individua...

journal_title：Chemical senses

authors： Smith TE,Tomlinson AJ,Mlotkiewicz JA,Abbott DH

更新日期：2001-06-01 00:00:00

abstract：:We have developed a strategy for the rapid high-throughput screening of odor responsivity in genetically altered mice (in fact, any experimentally altered animal). Specifically, the report presents the development and validation of a fully automated procedure based on the evaluation of an animal's stimulus-induced ref...

journal_title：Chemical senses

authors： Youngentob SL

更新日期：2005-03-01 00:00:00

abstract：:In social insects, recognition of nestmates from aliens is based on olfactory cues, and many studies have demonstrated that such cues are contained within the lipid layer covering the insect cuticle. These lipids are usually a complex mixture of tens of compounds in which aliphatic hydrocarbons are generally the major...

journal_title：Chemical senses

authors： Dani FR,Jones GR,Corsi S,Beard R,Pradella D,Turillazzi S

更新日期：2005-07-01 00:00:00

abstract：:The effects of the membrane-permeable dibutyryl guanosine 3', 5'-cyclic monophosphate (db-cGMP) on the bombykol-elicited receptor current and nerve impulse activity were studied using the open sensillum recording technique. db-cGMP was applied to the outer dendritic membrane of the olfactory receptor neuron of the mot...

journal_title：Chemical senses

authors： Redkozubov A

更新日期：2000-08-01 00:00:00

abstract：:Electrophysiological responses of olfactory receptor neurons in both male and female silkmoths (Bombyx mori) were investigated. In both sexes, the G-protein activator sodium fluoride and 1,2-dioctanoyl-sn-glycerol, a membrane-permeable analog of the protein kinase C activator diacylglycerol, elicited nerve impulse res...

journal_title：Chemical senses

authors： Pophof B,Van der Goes van Naters W

更新日期：2002-06-01 00:00:00

abstract：:Chemosensory receptors, including odor, taste, and vomeronasal receptors, comprise the largest group of G protein-coupled receptors (GPCRs) in the mammalian genome. However, little is known about the molecular determinants that are critical for the detection and discrimination of ligands by most of these receptors. Th...

journal_title：Chemical senses

authors： Nie Y,Hobbs JR,Vigues S,Olson WJ,Conn GL,Munger SD

更新日期：2006-07-01 00:00:00

abstract：:The Grueneberg ganglion (GG) in the vestibule of the anterior nasal cavity is considered as an olfactory subcompartment based on expression of the olfactory marker protein (OMP) and axonal projection to the olfactory bulb. Searching for olfactory receptors present in the GG, it has been observed recently that V2r83, a...

journal_title：Chemical senses

authors： Fleischer J,Schwarzenbacher K,Breer H

更新日期：2007-07-01 00:00:00

abstract：:Honeybees rely on nectar as their main source of carbohydrates. Sucrose, glucose, and fructose are the main components of plant nectars. Intriguingly, honeybees express only 3 putative sugar receptors (AmGr1, AmGr2, and AmGr3), which is in stark contrast to many other insects and vertebrates. The sugar receptors are o...

journal_title：Chemical senses

authors： Değirmenci L,Geiger D,Rogé Ferreira FL,Keller A,Krischke B,Beye M,Steffan-Dewenter I,Scheiner R

更新日期：2020-11-07 00:00:00

abstract：:The aim of this study was to investigate the relationship of fungiform papillae density with taste detection thresholds for sucrose of young male adults. One hundred and eighty two subjects aged 18-23 years (mean age: 21.9 +/- 1.2 years) were included. The densities of fungiform papillae were recorded with the aid of ...

journal_title：Chemical senses

authors： Zhang GH,Zhang HY,Wang XF,Zhan YH,Deng SP,Qin YM

更新日期：2009-01-01 00:00:00

abstract：:Olfactory function assessment is an important screening tool and also may differentiate Parkinson's disease (PD) patients from other parkinsonisms, including nondegenerative ones, such as, normal pressure hydrocephalus, vascular, drug induced, or infectious parkinsonism. Several authors in different countries have rep...

journal_title：Chemical senses

authors： Millar Vernetti P,Rossi M,Cerquetti D,Perez Lloret S,Merello M

更新日期：2016-01-01 00:00:00

abstract：:Regarding the chemotaxis of sperms, new insights have been gained during the last 20 years. Olfactory receptors are expressed on the flagellar midpiece of human spermatogenic cells. One of them, OR1D2, is also expressed in the olfactory epithelium. This receptor has been suggested to play a role in sperm chemotaxis an...

journal_title：Chemical senses

authors： Sinding C,Kemper E,Spornraft-Ragaller P,Hummel T

更新日期：2013-06-01 00:00:00

abstract：:Analysis of single fibers isolated from a branch of the facial/trigeminal complex innervating the maxillary barbel of the channel catfish, Ictalurus punctatus, indicated the existence of bimodal (taste/tactile) fibers. Of the 60 single fibers recorded, 14 (23%) responded to both taste (amino acid) and tactile stimulat...

journal_title：Chemical senses

authors： Ogawa K,Marui T,Caprio J

更新日期：1997-08-01 00:00:00

abstract：:It has been proposed that memory for odors does not have a short-term (or working) memory system. The distinction between short- and long-term memory in other sensory modalities has been generally supported by three main lines of evidence: capacity differences between the proposed systems, evidence of differential cod...

journal_title：Chemical senses

authors： White TL

更新日期：1998-08-01 00:00:00

abstract：:Electrical stimulation of the frog glossopharyngeal (GP) nerve evoked slow hyperpolarizing potentials (HPs) in taste cells. This study aimed to clarify whether slow HPs were postsynaptically induced in taste cells. The slow HPs were recorded intracellularly with a microelectrode. When Ca2+ concentration in the blood p...

journal_title：Chemical senses

authors： Sato T,Okada Y,Toda K

更新日期：2004-10-01 00:00:00

abstract：:The reported effects of temperature on sweet taste in humans have generally been small and inconsistent. Here, we describe 3 experiments that follow up a recent finding that cooling from 37 to 21 °C does not reduce the initial sweetness of sucrose but increases sweet taste adaptation. In experiment 1, subjects rated t...

journal_title：Chemical senses

authors： Green BG,Nachtigal D

更新日期：2015-07-01 00:00:00

abstract：:Contrary to what has often been said about the subject, decline in taste sensitivity with aging characterizes virtually everybody and is not the artificial result of averaging large losses of a minority with negligible losses of a majority. This assertion is supported by six repeated measures of sucrose thresholds in ...

journal_title：Chemical senses

authors： Stevens JC,Cruz LA,Hoffman JM,Patterson MQ

更新日期：1995-08-01 00:00:00

abstract：:Presynaptic inhibition is the suppression of neurotransmitter release from a neuron by inhibitory input onto its presynaptic terminal. In the olfactory system, the primary sensory afferents from the olfactory neuroepithelium to the brain's olfactory bulb are strongly modulated by a presynaptic inhibition that has been...

journal_title：Chemical senses

authors： McGann JP

更新日期：2013-07-01 00:00:00

abstract：:To date, most studies on the relationship between chemosensory performance and quality of life have focused on orthonasal measures of olfactory function. In the current investigation, we examined the predictive value of orthonasal and flavor identification indices of olfactory function on a wide spectrum of health and...

journal_title：Chemical senses

authors： Oleszkiewicz A,Park D,Resler K,Draf J,Schulze A,Zang Y,Hähner A,Hummel T

更新日期：2019-07-17 00:00:00

abstract：:Transcriptional regulation is an important mechanism by which neurons adapt to environmental stimuli. The indirect dopamine agonists, amphetamine and cocaine have been shown to induce expression of immediate early genes, such as c-fos, and neuropeptide genes, such as prodynorphin in the rat striatum. Here we show that...

journal_title：Chemical senses

authors： Hyman SE,Cole RL,Konradi C,Kosofsky BE

更新日期：1995-04-01 00:00:00

abstract：:This study determined taste thresholds for copper as its speciation was varied among free cupric ion, complexed cupric ion, and precipitated cupric particles. The impact of copper chemistry on taste is important as copper is added to many beverages and can be present in drinking water as a natural mineral or due to co...

journal_title：Chemical senses

authors： Cuppett JD,Duncan SE,Dietrich AM

更新日期：2006-09-01 00:00:00

abstract：:When the glossopharyngeal (GP) nerve of the frog was stimulated electrically, electropositive slow potentials were recorded from the tongue surface and depolarizing slow potentials from taste cells in the fungiform papillae. The amplitude of the slow potentials was stimulus strength- and the frequency-dependent. Gener...

journal_title：Chemical senses

authors： Sato T,Toda K,Miyamoto T,Okada Y,Fujiyama R

更新日期：2000-10-01 00:00:00

abstract：:Since the discovery of adult neurogenesis, a major issue is the role of newborn neurons and the function-dependent regulation of adult neurogenesis. We decided to use an animal model with a relatively simple brain to address these questions. In the adult cricket brain as in mammals, new neurons are produced throughout...

journal_title：Chemical senses

authors： Cayre M,Scotto-Lomassese S,Malaterre J,Strambi C,Strambi A

更新日期：2007-05-01 00:00:00

abstract：:Parasympathetic nerve (PSN) innervates taste cells of the frog taste disk, and electrical stimulation of PSN elicited a slow hyperpolarizing potential (HP) in taste cells. Here we report that gustatory receptor potentials in frog taste cells are depressed by PSN-induced slow HPs. When PSN was stimulated at 30 Hz durin...

journal_title：Chemical senses

authors： Sato T,Nishishita K,Mineda T,Okada Y,Toda K

更新日期：2007-01-01 00:00:00

abstract：:In order to assess the influence of odors on human performance and implicit memory for odors, 108 subjects completed a variety of tests in weakly scented (jasmine, lavender or odorless) rooms without having been made aware of the odor. After a 30 min interval the subjects were shown slides of different surroundings, i...

journal_title：Chemical senses

authors： Degel J,Köster EP

更新日期：1999-06-01 00:00:00