解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In working and practical contexts, dogs rely upon their ability to discriminate a target odor from distracting odors and other sensory stimuli. Using awake functional magnetic resonance imaging (fMRI) in 18 dogs, we examined the neural mechanisms underlying odor discrimination between 2 odors and a mixture of the odor...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjaa068
更新日期:2020-12-05 00:00:00
abstract::Honeybees rely on nectar as their main source of carbohydrates. Sucrose, glucose, and fructose are the main components of plant nectars. Intriguingly, honeybees express only 3 putative sugar receptors (AmGr1, AmGr2, and AmGr3), which is in stark contrast to many other insects and vertebrates. The sugar receptors are o...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjaa063
更新日期:2020-11-07 00:00:00
abstract::Experience is an essential factor informing food choice. Eating food generates enduring odor-taste associations that link an odor with a taste's quality and hedonic value (pleasantness/unpleasantness) and creates the perception of a congruent odor-taste combination. Previous human psychophysical experiments demonstrat...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjaa025
更新日期:2020-05-29 00:00:00
abstract::Taste perception is important for animals to take adequate nutrients and avoid toxins for their survival. Appetitive and aversive behaviors are produced by value evaluation of taste and taste expectation caused by other sensations. The value evaluation, coupled with a cue presentation, produces outcome expectation and...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjz066
更新日期:2020-01-01 00:00:00
abstract::Evidence suggests that women outperform men in core aspects of odor perception, and sex hormones may play a significant role in moderating this effect. The gender-affirming treatment (GAT) of transgender persons constitutes a powerful natural experiment to study the psychological and behavioral effects of high dosages...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjz069
更新日期:2020-01-01 00:00:00
abstract::To date, most studies on the relationship between chemosensory performance and quality of life have focused on orthonasal measures of olfactory function. In the current investigation, we examined the predictive value of orthonasal and flavor identification indices of olfactory function on a wide spectrum of health and...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjz027
更新日期:2019-07-17 00:00:00
abstract::Recognition of individuals or classes of individuals plays an important role in the communication systems of many mammals. The ability of otariid (i.e., fur seal and sea lion) females to locate and identify their offspring in colonies after returning from regular foraging trips is essential to successful pup rearing. ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjz008
更新日期:2019-03-11 00:00:00
abstract::Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy074
更新日期:2019-01-01 00:00:00
abstract::Nasal inhalation is the basis of olfactory perception and drives neural activity in olfactory and limbic brain regions. Therefore, our ability to investigate the neural underpinnings of olfaction and respiration can only be as good as our ability to characterize features of respiratory behavior. However, recordings of...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy045
更新日期:2018-09-22 00:00:00
abstract::Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjy044
更新日期:2018-08-24 00:00:00
abstract::Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy025
更新日期:2018-07-05 00:00:00
abstract::Odors are inherently ambiguous and therefore susceptible to redundant sensory as well as context information. The identification of an odor object relies largely on visual input. Thus far, it is unclear whether visual and olfactory stimuli are indeed integrated at an early perceptual stage and which role the congruenc...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy018
更新日期:2018-05-23 00:00:00
abstract::Many studies have indicated that the chemical cues from body odors (BOs) of donors experiencing negative emotions can influence the psychophysiological and behavioral response of the observers. However, these olfactory cues have been used mainly as contextual information for processing visual stimuli. Here, for the fi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy021
更新日期:2018-05-23 00:00:00
abstract::Despite long and intense research, some fundamental questions regarding representation of taste information in the brain still remain unanswered. This might in part be due to shortcomings of the established methods that limit the researcher either to thorough characterization of few elements or to analyze the response...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy017
更新日期:2018-04-23 00:00:00
abstract::Previous studies have reported that the umami taste of monosodium l-glutamate (MSG) and salty-smelling odors (e.g., soy sauce, bacon, sardines) enhance the perception of saltiness. This study aimed to investigate the neural basis of the enhancement of saltiness in human participants using functional near-infrared spec...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjx084
更新日期:2018-02-26 00:00:00
abstract::The prevalence of obesity and obesity-related disorders such as type 2 diabetes (T2D) and metabolic syndrome has increased significantly in the past decades, reaching epidemic levels and therefore becoming a major health issue worldwide. Chronic overeating of highly palatable foods is one of the main responsible aspec...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx062
更新日期:2017-12-25 00:00:00
abstract::Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjx060
更新日期:2017-10-31 00:00:00
abstract::Since starch is a significant part of human diet, its oral detection would be highly beneficial. This study was designed to determine whether starch or its degradation products can be tasted and what factors influence its perception. Subjects were asked 1) to taste 8% raw and cooked starch samples for 5, 15, and 35 s ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjx042
更新日期:2017-10-01 00:00:00
abstract::Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx028
更新日期:2017-10-01 00:00:00
abstract::Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx025
更新日期:2017-09-01 00:00:00
abstract::Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjx040
更新日期:2017-09-01 00:00:00
abstract::Taste sensitivity plays a major role in controlling feeding behavior, and alterations in feeding habit induced by changes in taste sensitivity can drive speciation. We investigated variability in taste preferences in wild-derived inbred lines from the Drosophila melanogaster Genetic Reference Panel. Preferences for di...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw165
更新日期:2017-05-01 00:00:00
abstract::Cigarettes are an often-used consumer product, and flavor is an important determinant of their product appeal. Cigarettes with strong nontobacco flavors are popular among young people, and may facilitate smoking initiation. Discriminating flavors in tobacco is important for regulation purposes, for instance to set upp...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw123
更新日期:2017-03-01 00:00:00
abstract::The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjx002
更新日期:2017-03-01 00:00:00
abstract::Three experiments assessed potential changes in the rat's perception of sodium chloride (NaCl) during a state of sodium appetite. In Experiment 1, sodium-sufficient rats licking a range of NaCl concentrations (0.028-0.89M) in 15s trials showed an inverted U-shaped concentration response function peaking at 0.281M. Dep...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw100
更新日期:2017-02-01 00:00:00
abstract::Olfactory perception is highly variable from one person to another, as a function of individual and contextual factors. Here, we investigated the influence of 2 important factors of variation: culture and semantic information. More specifically, we tested whether cultural-specific knowledge and presence versus absence...
journal_title:Chemical senses
pub_type: 临床试验,杂志文章
doi:10.1093/chemse/bjw098
更新日期:2017-01-01 00:00:00
abstract::The role of odors in the long-distance navigation of birds has elicited intense debate for more than half a century. Failure to resolve many of the issues fueling this debate is due at least in part to the absence of controls for a variety of non-specific effects that odors have on the navigational process. The presen...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw084
更新日期:2016-11-01 00:00:00
abstract::In rodents, the vomeronasal system controls social and sexual behavior. However, several mechanistic aspects of sensory signaling in the vomeronasal organ remain unclear. Here, we investigate the biophysical basis of a recently proposed vomeronasal signal transduction component-a Ca(2+)-activated Cl(-) current. As the...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw077
更新日期:2016-10-01 00:00:00
abstract::The experiments had 2 main goals: 1) to add to the sparse literature on how retronasal aromas interact with bitter tastes, and 2) to determine whether modulation of taste intensity by aroma depends on temporal contiguity, as one might expect if flavor interactions depend on cross-modal binding (similar to object perce...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw059
更新日期:2016-09-01 00:00:00
abstract::Glutathione, a natural substance, acts on calcium receptors on the tongue and is known to enhance basic taste sensations. However, the effects of glutathione on brain activity associated with taste sensation on the tongue have not been determined under standardized taste delivery conditions. In this study, we investig...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw066
更新日期:2016-09-01 00:00:00
abstract::Mosquito control is essential to protect humans from mosquito-borne diseases. The host recognition between mosquitoes and humans is achieved by the mosquito olfactory system. Antennal sensilla, which house olfactory receptor neurons, are responsible for detecting chemical cues from hosts. To deepen our understanding o...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv089
更新日期:2016-06-01 00:00:00
abstract::Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to indu...
journal_title:Chemical senses
pub_type: 杂志文章,随机对照试验
doi:10.1093/chemse/bjv068
更新日期:2016-02-01 00:00:00
abstract::Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv072
更新日期:2016-02-01 00:00:00
abstract::The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv065
更新日期:2016-02-01 00:00:00
abstract::Olfactory function assessment is an important screening tool and also may differentiate Parkinson's disease (PD) patients from other parkinsonisms, including nondegenerative ones, such as, normal pressure hydrocephalus, vascular, drug induced, or infectious parkinsonism. Several authors in different countries have rep...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv062
更新日期:2016-01-01 00:00:00
abstract::Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally (IP) into C57BL/6 mi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv059
更新日期:2016-01-01 00:00:00
abstract::Although the honeybee (Apis mellifera) is one of the world most studied insects, the chemical compounds used in nestmate recognition, remains an open question. By exploiting the error prone recognition system of the honeybee, coupled with genotyping, we studied the correlation between cuticular hydrocarbon (CHC) profi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv053
更新日期:2015-11-01 00:00:00
abstract::It is commonly agreed upon a strong link between emotion and olfaction. Odor-evoked memories are experienced as more emotional compared with verbal, visual, and tactile stimuli. Moreover, the emotional quality of odor cues increases memory performance, but contrary to this, odors are poor retrieval cues for verbal lab...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv037
更新日期:2015-09-01 00:00:00
abstract::Studies over the last 8 years have identified 3 potential channels that appear to release ATP from Type II cells in response to taste stimuli. These studies have taken different methodological approaches but have all provided data supporting their candidate channel as the ATP release channel. These potential channels ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv035
更新日期:2015-09-01 00:00:00
abstract::The reported effects of temperature on sweet taste in humans have generally been small and inconsistent. Here, we describe 3 experiments that follow up a recent finding that cooling from 37 to 21 °C does not reduce the initial sweetness of sucrose but increases sweet taste adaptation. In experiment 1, subjects rated t...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv021
更新日期:2015-07-01 00:00:00