Abstract:
:The reported effects of temperature on sweet taste in humans have generally been small and inconsistent. Here, we describe 3 experiments that follow up a recent finding that cooling from 37 to 21 °C does not reduce the initial sweetness of sucrose but increases sweet taste adaptation. In experiment 1, subjects rated the sweetness of sucrose, glucose, and fructose solutions at 5-41 °C by dipping the tongue tip into the solutions after 0-, 3-, or 10-s pre-exposures to the same solutions or to H2O; experiment 2 compared the effects of temperature on the sweetness of 3 artificial sweeteners (sucralose, aspartame, and saccharin); and experiment 3 employed a flow-controlled gustometer to rule out the possibility the effects of temperature in the preceding experiments were unique to dipping the tongue into a still taste solution. The results (i) confirmed that mild cooling does not attenuate sweetness but can increase sweet taste adaptation; (ii) demonstrated that cooling to 5-12 °C can directly reduce sweetness intensity; and (iii) showed that both effects vary across stimuli. These findings have implications for the TRPM5 hypothesis of thermal effects on sweet taste and raise the possibility that temperature also affects an earlier step in the T1R2-T1R3 transduction cascade.
journal_name
Chem Sensesjournal_title
Chemical sensesauthors
Green BG,Nachtigal Ddoi
10.1093/chemse/bjv021subject
Has Abstractpub_date
2015-07-01 00:00:00pages
391-9issue
6eissn
0379-864Xissn
1464-3553pii
bjv021journal_volume
40pub_type
杂志文章相关文献
CHEMICAL SENSES文献大全abstract::Suppression of the saltiness of NaCl solutions by amiloride, a sodium channel blocker, has previously been reported a number of times in humans. This suppression was seen with techniques that involved stimulation of small areas of the tongue. It was not certain, however, whether amiloride would suppress saltiness with...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/21.2.113
更新日期:1996-04-01 00:00:00
abstract::The effects of the membrane-permeable dibutyryl guanosine 3', 5'-cyclic monophosphate (db-cGMP) on the bombykol-elicited receptor current and nerve impulse activity were studied using the open sensillum recording technique. db-cGMP was applied to the outer dendritic membrane of the olfactory receptor neuron of the mot...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.4.381
更新日期:2000-08-01 00:00:00
abstract::Our study was designed to examine how components of complex mixtures can inhibit the binding of other components to receptor sites in the olfactory system of the spiny lobster Panulirus argus. Biochemical binding assays were used to study how two- to six-component mixtures inhibit binding of the radiolabeled odorants ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/23.3.269
更新日期:1998-06-01 00:00:00
abstract::Past research has shown that odor perception can be affected by how we label odors. The aim of this study was to expand on previous work by investigating the impact of labels on edibility, pleasantness, and intensity ratings as well as on reaction times when detecting labeled odors. We tested 50 subjects. Five odorant...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjt066
更新日期:2014-02-01 00:00:00
abstract::Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx025
更新日期:2017-09-01 00:00:00
abstract::When one taste (masker) is strong enough, it can completely mask another task (target) of different quality. How strong the masker must be to do this depends on how strong the target is. As the target concentration is increased, the masking concentration must be increased, too, but in ever-increasing proportion. To qu...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/21.2.211
更新日期:1996-04-01 00:00:00
abstract::Restriction of dietary sodium during gestation has major effects on taste function and anatomy in the offspring. The chorda tympani nerve of offspring that are maintained on sodium-reduced chow throughout life (NaDep) has reduced neurophysiological responses to sodium and altered morphology of its terminal field in th...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.6.719
更新日期:2000-12-01 00:00:00
abstract::During the past 2 decades, considerable progress has been made in the study of bird semiochemistry, and our goal was to review and evaluate this literature with particular emphasis on the volatile organic constituents. Indeed, since the importance of social chemosignaling in birds is becoming more and more apparent, t...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjr067
更新日期:2012-01-01 00:00:00
abstract::Rats can be classified as either sucralose avoiders (SA) or sucralose preferrers (SP) based on their behavioral responses in 2-bottle preference, 1-bottle intake, and brief-access licking tests. The present study demonstrates that this robust phenotypic variation in the preference for sucralose predicts acceptance of ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjr126
更新日期:2012-06-01 00:00:00
abstract::The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv065
更新日期:2016-02-01 00:00:00
abstract::Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv072
更新日期:2016-02-01 00:00:00
abstract::There is no natural physical continuum for odor quality along which an odor quality discrimination (OQD) threshold can be measured. In an attempt to overcome this problem, the substitution-reciprocity (SURE) method defines a framework for the measurement of an OQD threshold. More specifically, it (i) defines a thresho...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.5.493
更新日期:2000-10-01 00:00:00
abstract::Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx028
更新日期:2017-10-01 00:00:00
abstract::To examine the functional subdivision of the teleost olfactory bulb, extracellular recordings were made from the posterior part of the medial region of the olfactory bulb in the crucian carp, Carassius carassius. Bulbar units classified as type I or type II were frequently and simultaneously encountered at a recording...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/28.3.181
更新日期:2003-03-01 00:00:00
abstract::Since the discovery of adult neurogenesis, a major issue is the role of newborn neurons and the function-dependent regulation of adult neurogenesis. We decided to use an animal model with a relatively simple brain to address these questions. In the adult cricket brain as in mammals, new neurons are produced throughout...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjm010
更新日期:2007-05-01 00:00:00
abstract::The septal organ of Masera (SO) is a small, isolated patch of olfactory epithelium, located in the ventral part of the nasal septum. We investigated in this systematic study the postnatal development of the SO in histological sections of rats at various ages from the day of birth (P1) to P666. The SO-area increases to...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjg047
更新日期:2003-09-01 00:00:00
abstract::Individual recognition has been studied across a number of taxa and modalities; however, few attempts have been made to combine chemical and biological approaches and arrive at a more complete understanding of the use of secretions as signals. We combined behavioral habituation experiments with gas chromatography-mass...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjr055
更新日期:2011-11-01 00:00:00
abstract::Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally (IP) into C57BL/6 mi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv059
更新日期:2016-01-01 00:00:00
abstract::In this study, we cloned and characterized three Manduca sexta odorant receptors (ORs). One receptor is a putative pheromone receptor expressed exclusively in a cell associated with male-specific type-I trichoid sensilla. We describe the results of real-time PCR (RT-PCR) and quantitative real-time PCR (qRT-PCR) experi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjp002
更新日期:2009-05-01 00:00:00
abstract::The terminal nerve, which innervates the nasal epithelia of most jawed vertebrates, is believed to release neuropeptides that modulate activity of sensory receptor neurons. The terminal nerve usually contains gonadotropin-releasing hormone as well as at least one other peptide that has not been characterized, but whic...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/28.4.339
更新日期:2003-05-01 00:00:00
abstract::The purpose of this study was to determine the degree to which the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid (Na-PMP) reduced sweet intensity ratings of 15 sweeteners in mixtures. Na-PMP has been approved for use in confectionary/frostings, soft candy and snack products in the USA at concentrations up to 15...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/24.4.439
更新日期:1999-08-01 00:00:00
abstract::The distribution of sugar chains on tissue sections of the rat vomeronasal epithelium, and the adhesive force between the sugar and its specific lectin were examined with an atomic force microscope (AFM). AFM tips were modified with a lectin, Vicia villosa agglutinin, which recognizes terminal N-acetyl-D-galactosamine...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/24.1.1
更新日期:1999-02-01 00:00:00
abstract::To examine whether age influences taste solution preferences, we measured taste preferences of C57BL/6J and 129X1/SvJ mice given a series of 48-h 2-bottle tests with a choice between water and one of the following taste solutions: 2 mM saccharin, 5 mM citric acid, 30 microM quinine hydrochloride, 75 mM sodium chloride...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjm034
更新日期:2007-09-01 00:00:00
abstract::Olfaction involves a dual sensory process for perceiving odors orthonasally (through the nostrils) and retronasally (through the mouth). This investigation entailed developing a measure of sensitivity to an odor delivered in an orally sampled food (orange flavoring in a sucrose-sweetened gelatin) and examining sensiti...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/24.6.671
更新日期:1999-12-01 00:00:00
abstract::Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjl037
更新日期:2007-02-01 00:00:00
abstract::Insect odorant receptors (ORs) function as heteromeric odorant-gated ion channels consisting of a conserved coreceptor, Orco, and an odorant-sensitive tuning subunit. Although some OR modulators have been identified, an extended library of pharmacological tools is currently lacking and would aid in furthering our unde...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjs100
更新日期:2013-03-01 00:00:00
abstract::Many studies have indicated that the chemical cues from body odors (BOs) of donors experiencing negative emotions can influence the psychophysiological and behavioral response of the observers. However, these olfactory cues have been used mainly as contextual information for processing visual stimuli. Here, for the fi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy021
更新日期:2018-05-23 00:00:00
abstract::Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjp088
更新日期:2010-02-01 00:00:00
abstract::The present study analyzed 42 organic solvent extracts of scent mark pools from five dominant female common marmosets by gas chromatography (GC) and combined GC and mass spectrometry. We determined whether there were qualitative or quantitative differences between the chemical composition of scent marks from individua...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/26.5.449
更新日期:2001-06-01 00:00:00
abstract::Glutathione, a natural substance, acts on calcium receptors on the tongue and is known to enhance basic taste sensations. However, the effects of glutathione on brain activity associated with taste sensation on the tongue have not been determined under standardized taste delivery conditions. In this study, we investig...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw066
更新日期:2016-09-01 00:00:00