Rapid degeneration and regeneration of the zebrafish olfactory epithelium after triton X-100 application.

abstract：:Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...

journal_title：Chemical senses

authors： Leopold D

更新日期：2002-09-01 00:00:00

abstract：:To examine whether age influences taste solution preferences, we measured taste preferences of C57BL/6J and 129X1/SvJ mice given a series of 48-h 2-bottle tests with a choice between water and one of the following taste solutions: 2 mM saccharin, 5 mM citric acid, 30 microM quinine hydrochloride, 75 mM sodium chloride...

journal_title：Chemical senses

authors： Tordoff MG

更新日期：2007-09-01 00:00:00

abstract：:The stimuli used in taste research are usually considered to be odourless. This was tested in two experiments with aqueous solutions of two representative compounds for each of the five taste qualities including umami. In the first experiment elderly and young subjects rated the intensity and pleasantness of three con...

journal_title：Chemical senses

authors： Mojet J,Köster EP,Prinz JF

更新日期：2005-01-01 00:00:00

abstract：:The effect of task duration on odor discrimination in aging was studied. Twenty-seven young male adults and 24 young female adults between 18 and 30 years of age, and 17 older male adults between 45 and 65 years of age completed an odor discrimination task. The odor discrimination task consisted of two parts of 16 tri...

journal_title：Chemical senses

authors： Hulshoff Pol HE,Hijman R,Baaré WF,van Eekelen S,van Ree JM

更新日期：2000-08-01 00:00:00

abstract：:A previous study investigating individuals' bitterness sensitivities found a close association among three compounds: L-tryptophan (L-trp), L-phenylalanine (L-phe) and urea (Delwiche et al., 2001, Percept. Psychophys. 63, 761-776). In the present experiment, psychophysical cross-adaptation and bitterness inhibition ex...

journal_title：Chemical senses

authors： Keast RS,Breslin PA

更新日期：2002-02-01 00:00:00

abstract：:When one taste (masker) is strong enough, it can completely mask another task (target) of different quality. How strong the masker must be to do this depends on how strong the target is. As the target concentration is increased, the masking concentration must be increased, too, but in ever-increasing proportion. To qu...

journal_title：Chemical senses

authors： Stevens JC

更新日期：1996-04-01 00:00:00

abstract：:We are proposing that the "relative" abundances of the differently tuned pheromone-component-responsive olfactory receptor neurons (ORNs) on insect antennae are not a result of natural selection working to maximize absolute sensitivity to individual pheromone components. Rather, relative abundances are a result of spe...

journal_title：Chemical senses

authors： Baker TC,Domingue MJ,Myrick AJ

更新日期：2012-05-01 00:00:00

abstract：:The sense of smell deteriorates in normal aging, but the underling mechanisms are still elusive. Here we investigated age-related alterations in expression patterns of odorant receptor (OR) genes and functional properties of olfactory sensory neurons (OSNs)-2 critical factors that define the odor detection threshold i...

journal_title：Chemical senses

authors： Lee AC,Tian H,Grosmaitre X,Ma M

更新日期：2009-10-01 00:00:00

abstract：:The strong bond that is formed between ewe and lamb after parturition is important for lamb survival. Evidence exists that the ewe mainly employs olfactory recognition cues to distinguish her lamb from other lambs in the flock. We have found that volatile organic compounds in the wool of Merino lambs that presumably c...

journal_title：Chemical senses

authors： Viviers MZ,Burger BV,le Roux NJ,Morris J,le Roux M

更新日期：2014-03-01 00:00:00

abstract：:Olfaction involves a dual sensory process for perceiving odors orthonasally (through the nostrils) and retronasally (through the mouth). This investigation entailed developing a measure of sensitivity to an odor delivered in an orally sampled food (orange flavoring in a sucrose-sweetened gelatin) and examining sensiti...

journal_title：Chemical senses

authors： Duffy VB,Cain WS,Ferris AM

更新日期：1999-12-01 00:00:00

abstract：:Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...

journal_title：Chemical senses

authors： Wang Q,Titlow WB,McClintock DA,Stromberg AJ,McClintock TS

更新日期：2017-10-01 00:00:00

abstract：:Many previous studies have attempted to investigate the effect of visual cues on olfactory perception in humans. The majority of this research has only looked at the modulatory effect of color, which has typically been explained in terms of multisensory perceptual interactions. However, such crossmodal effects may equ...

journal_title：Chemical senses

authors： Demattè ML,Sanabria D,Spence C

更新日期：2009-02-01 00:00:00

abstract：:Analysis of single fibers isolated from a branch of the facial/trigeminal complex innervating the maxillary barbel of the channel catfish, Ictalurus punctatus, indicated the existence of bimodal (taste/tactile) fibers. Of the 60 single fibers recorded, 14 (23%) responded to both taste (amino acid) and tactile stimulat...

journal_title：Chemical senses

authors： Ogawa K,Marui T,Caprio J

更新日期：1997-08-01 00:00:00

abstract：:Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....

journal_title：Chemical senses

authors： Mojet J,Christ-Hazelhof E,Heidema J

更新日期：2001-09-01 00:00:00

abstract：:Female gypsy moths emit a pheromone, (+)-disparlure, which the males follow until they locate the emitter. The male moths' antennae are covered with innervated sensory hairs, specialized in detection of the pheromone. The neurons in these sensory hairs are bathed by a solution rich in pheromone-binding protein (PBP). ...

journal_title：Chemical senses

authors： Gong Y,Plettner E

更新日期：2011-03-01 00:00:00

abstract：:Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

journal_title：Chemical senses

authors： Lovelace CT,Slotnick BM

更新日期：1995-04-01 00:00:00

abstract：:The G protein subunit alpha-gustducin is expressed in a subset of light (Type II) but not in dark (Type I) cells in rat vallate taste buds. The thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) is incorporated into DNA during the S-phase of the cell cycle and can be used to determine the time of origin of a cell. In t...

journal_title：Chemical senses

authors： Cho YK,Farbman AI,Smith DV

更新日期：1998-12-01 00:00:00

abstract：:Rats can be classified as either sucralose avoiders (SA) or sucralose preferrers (SP) based on their behavioral responses in 2-bottle preference, 1-bottle intake, and brief-access licking tests. The present study demonstrates that this robust phenotypic variation in the preference for sucralose predicts acceptance of ...

journal_title：Chemical senses

authors： Loney GC,Torregrossa AM,Carballo C,Eckel LA

更新日期：2012-06-01 00:00:00

abstract：:Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...

journal_title：Chemical senses

authors： Leow LP,Huckabee ML,Sharma S,Tooley TP

更新日期：2007-02-01 00:00:00

abstract：:Adaptation techniques have traditionally been employed in sensory physiology and psychology to characterize afferent pathways and to dissect the quantitative and, to a lesser degree, the qualitative aspects of perception. We continue to explore the individual differences in olfactory capabilities among subjects initia...

journal_title：Chemical senses

authors： O'Connell RJ,Stevens DA,Zogby LM

更新日期：1994-06-01 00:00:00

abstract：:Glutathione, a natural substance, acts on calcium receptors on the tongue and is known to enhance basic taste sensations. However, the effects of glutathione on brain activity associated with taste sensation on the tongue have not been determined under standardized taste delivery conditions. In this study, we investig...

journal_title：Chemical senses

authors： Goto TK,Yeung AW,Tanabe HC,Ito Y,Jung HS,Ninomiya Y

更新日期：2016-09-01 00:00:00

abstract：:During the past 2 decades, considerable progress has been made in the study of bird semiochemistry, and our goal was to review and evaluate this literature with particular emphasis on the volatile organic constituents. Indeed, since the importance of social chemosignaling in birds is becoming more and more apparent, t...

journal_title：Chemical senses

authors： Campagna S,Mardon J,Celerier A,Bonadonna F

更新日期：2012-01-01 00:00:00

abstract：:The prevalence of obesity and obesity-related disorders such as type 2 diabetes (T2D) and metabolic syndrome has increased significantly in the past decades, reaching epidemic levels and therefore becoming a major health issue worldwide. Chronic overeating of highly palatable foods is one of the main responsible aspec...

journal_title：Chemical senses

authors： Tarragon E,Moreno JJ

更新日期：2017-12-25 00:00:00

abstract：:Since starch is a significant part of human diet, its oral detection would be highly beneficial. This study was designed to determine whether starch or its degradation products can be tasted and what factors influence its perception. Subjects were asked 1) to taste 8% raw and cooked starch samples for 5, 15, and 35 s ...

journal_title：Chemical senses

authors： Lapis TJ,Penner MH,Balto AS,Lim J

更新日期：2017-10-01 00:00:00

abstract：:The antisense DNA method has been used successfully to block the expression of specific genes in vivo in neuronal systems. An increasing number of studies in the last few years have shown that antisense DNA administered directly into the brain can modify various kinds of behaviors. These findings strongly suggest that...

journal_title：Chemical senses

authors： Ogawa S,Pfaff DW

更新日期：1998-04-01 00:00:00

abstract：:Taste perception is important for animals to take adequate nutrients and avoid toxins for their survival. Appetitive and aversive behaviors are produced by value evaluation of taste and taste expectation caused by other sensations. The value evaluation, coupled with a cue presentation, produces outcome expectation and...

journal_title：Chemical senses

authors： Takei K,Fujita K,Kashimori Y

更新日期：2020-01-01 00:00:00

abstract：:Taste sensitivity is assessed with various techniques, including absolute detection and quality recognition. For any stimulus, one might expect individual differences in sensitivity to be reflected in all measures, but they are often surprisingly independent. Here, we focus on sensitivity to sour and salty taste, in p...

journal_title：Chemical senses

authors： Wise PM,Breslin PA

更新日期：2013-05-01 00:00:00

abstract：:Transcriptional regulation is an important mechanism by which neurons adapt to environmental stimuli. The indirect dopamine agonists, amphetamine and cocaine have been shown to induce expression of immediate early genes, such as c-fos, and neuropeptide genes, such as prodynorphin in the rat striatum. Here we show that...

journal_title：Chemical senses

authors： Hyman SE,Cole RL,Konradi C,Kosofsky BE

更新日期：1995-04-01 00:00:00

abstract：:We have measured concentration detection (i.e., psychometric) functions to determine the odor detectability of homologous aliphatic aldehydes (propanal, butanal, hexanal, octanal, and nonanal) and helional. Subjects (16 < or = n < or = 18) used a 3-alternative forced-choice procedure against carbon-filtered air (blank...

journal_title：Chemical senses

authors： Cometto-Muñiz JE,Abraham MH

更新日期：2010-05-01 00:00:00

abstract：:Three experiments assessed potential changes in the rat's perception of sodium chloride (NaCl) during a state of sodium appetite. In Experiment 1, sodium-sufficient rats licking a range of NaCl concentrations (0.028-0.89M) in 15s trials showed an inverted U-shaped concentration response function peaking at 0.281M. Dep...

journal_title：Chemical senses

authors： St John SJ

更新日期：2017-02-01 00:00:00