Distortion of olfactory perception: diagnosis and treatment.

abstract：:Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC...

journal_title：Chemical senses

authors： Wooding SP

更新日期：2018-08-24 00:00:00

abstract：:In 20 normal and four anosmic participants, instantaneous inhalation and exhalation flow rates were recorded in response to 15 s stimulations with clean air or propionic acid concentrations (0.16, 1.14, 8.22 and 59.15 p.p.m., v/v) that ranged from peri-threshold for normals to clearly supra-threshold for anosmics. Eac...

journal_title：Chemical senses

authors： Walker JC,Kendal-Reed M,Hall SB,Morgan WT,Polyakov VV,Lutz RW

更新日期：2001-05-01 00:00:00

abstract：:Contrary to what has often been said about the subject, decline in taste sensitivity with aging characterizes virtually everybody and is not the artificial result of averaging large losses of a minority with negligible losses of a majority. This assertion is supported by six repeated measures of sucrose thresholds in ...

journal_title：Chemical senses

authors： Stevens JC,Cruz LA,Hoffman JM,Patterson MQ

更新日期：1995-08-01 00:00:00

abstract：:The effect of soluble starch (acid-modified starch) on taste intensity was investigated in human subjects. Different concentrations of sucrose (Suc), six sweeteners, NaCl, quinine-HCl (QHCl) and citric acid (Cit) were dissolved in either distilled water (DW; standard) or starch solution (test solution). The solutions ...

journal_title：Chemical senses

authors： Kanemaru N,Harada S,Kasahara Y

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to investigate the relationship of fungiform papillae density with taste detection thresholds for sucrose of young male adults. One hundred and eighty two subjects aged 18-23 years (mean age: 21.9 +/- 1.2 years) were included. The densities of fungiform papillae were recorded with the aid of ...

journal_title：Chemical senses

authors： Zhang GH,Zhang HY,Wang XF,Zhan YH,Deng SP,Qin YM

更新日期：2009-01-01 00:00:00

abstract：:Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...

journal_title：Chemical senses

authors： Boesveldt S,Postma EM,Boak D,Welge-Luessen A,Schöpf V,Mainland JD,Martens J,Ngai J,Duffy VB

更新日期：2017-09-01 00:00:00

abstract：:Many previous studies have attempted to investigate the effect of visual cues on olfactory perception in humans. The majority of this research has only looked at the modulatory effect of color, which has typically been explained in terms of multisensory perceptual interactions. However, such crossmodal effects may equ...

journal_title：Chemical senses

authors： Demattè ML,Sanabria D,Spence C

更新日期：2009-02-01 00:00:00

abstract：:Experiments were performed to determine which bundles of the olfactory tracts were essential for mediating alarm reaction in crucian carp (Carassius carassius L.). The fish were maintained in physiological saline after surgery to preserve the remaining tracts and postoperative inspections revealed the functionality of...

journal_title：Chemical senses

authors： Hamdani EH,Stabell OB,Alexander G,Døving KB

更新日期：2000-02-01 00:00:00

abstract：:Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...

journal_title：Chemical senses

authors： Wang Q,Titlow WB,McClintock DA,Stromberg AJ,McClintock TS

更新日期：2017-10-01 00:00:00

abstract：:It is commonly agreed upon a strong link between emotion and olfaction. Odor-evoked memories are experienced as more emotional compared with verbal, visual, and tactile stimuli. Moreover, the emotional quality of odor cues increases memory performance, but contrary to this, odors are poor retrieval cues for verbal lab...

journal_title：Chemical senses

authors： Bestgen AK,Schulze P,Kuchinke L

更新日期：2015-09-01 00:00:00

abstract：:Chemical signals are common in most crustacean social interactions and are often perceived via chemosensory (olfactory) organs on the first antenna. Intermolt courtship behaviors and mating were investigated in size-matched pairs of intermolt European lobsters (Homarus gammarus) where the olfactory receptors of either...

journal_title：Chemical senses

authors： Skog M

更新日期：2009-02-01 00:00:00

abstract：:The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...

journal_title：Chemical senses

authors： Trimmer C,Mainland JD

更新日期：2017-03-01 00:00:00

abstract：:Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...

journal_title：Chemical senses

authors： Schwartz C,Chabanet C,Szleper E,Feyen V,Issanchou S,Nicklaus S

更新日期：2017-09-01 00:00:00

abstract：:Cells, identified as supporting cells by Lucifer Yellow injection, were recorded from slices of frog olfactory epithelium using patch-clamp recordings. Cell-attached single-channel recordings indicated that the intracellular potential (IP) was -68 +/- 7 mV (n = 22) with 4 mM K+ in the bath ([K+]o). IP was -67 +/- 4 mV...

journal_title：Chemical senses

authors： Trotier D

更新日期：1998-06-01 00:00:00

abstract：:Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...

journal_title：Chemical senses

authors： Leow LP,Huckabee ML,Sharma S,Tooley TP

更新日期：2007-02-01 00:00:00

abstract：:Rats can be classified as either sucralose avoiders (SA) or sucralose preferrers (SP) based on their behavioral responses in 2-bottle preference, 1-bottle intake, and brief-access licking tests. The present study demonstrates that this robust phenotypic variation in the preference for sucralose predicts acceptance of ...

journal_title：Chemical senses

authors： Loney GC,Torregrossa AM,Carballo C,Eckel LA

更新日期：2012-06-01 00:00:00

abstract：:Taste sensitivity plays a major role in controlling feeding behavior, and alterations in feeding habit induced by changes in taste sensitivity can drive speciation. We investigated variability in taste preferences in wild-derived inbred lines from the Drosophila melanogaster Genetic Reference Panel. Preferences for di...

journal_title：Chemical senses

authors： Uchizono S,Tanimura T

更新日期：2017-05-01 00:00:00

abstract：:Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....

journal_title：Chemical senses

authors： Mojet J,Christ-Hazelhof E,Heidema J

更新日期：2001-09-01 00:00:00

abstract：:Cigarettes are an often-used consumer product, and flavor is an important determinant of their product appeal. Cigarettes with strong nontobacco flavors are popular among young people, and may facilitate smoking initiation. Discriminating flavors in tobacco is important for regulation purposes, for instance to set upp...

journal_title：Chemical senses

authors： Krüsemann EJ,Cremers JW,Visser WF,Punter PH,Talhout R

更新日期：2017-03-01 00:00:00

abstract：:Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...

journal_title：Chemical senses

authors： Georgiopoulos C,Witt ST,Haller S,Dizdar N,Zachrisson H,Engström M,Larsson EM

更新日期：2018-07-05 00:00:00

abstract：:In acipenserids, crypt cells (CCs) have only been observed in juvenile specimens, and it has not been clarified whether they differentiate along with olfactory receptor neurons (ORNs) during the lecithotrophic stage or during later development stages. Furthermore, no detailed optical microscopy (OM) or electron micros...

journal_title：Chemical senses

authors： Camacho S,Ostos-Garrido MV,Domezain A,Carmona R

更新日期：2010-02-01 00:00:00

abstract：:In this study, we cloned and characterized three Manduca sexta odorant receptors (ORs). One receptor is a putative pheromone receptor expressed exclusively in a cell associated with male-specific type-I trichoid sensilla. We describe the results of real-time PCR (RT-PCR) and quantitative real-time PCR (qRT-PCR) experi...

journal_title：Chemical senses

authors： Patch HM,Velarde RA,Walden KK,Robertson HM

更新日期：2009-05-01 00:00:00

abstract：:The terminal nerve, which innervates the nasal epithelia of most jawed vertebrates, is believed to release neuropeptides that modulate activity of sensory receptor neurons. The terminal nerve usually contains gonadotropin-releasing hormone as well as at least one other peptide that has not been characterized, but whic...

journal_title：Chemical senses

authors： Park D,Zawacki SR,Eisthen HL

更新日期：2003-05-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:Glomeruli, neuropilar structures composed of olfactory receptor neuron (ORN) axon terminals and central neuron dendrites, are a common feature of olfactory systems. Typically, ORN axons segregate into glomeruli based on odor specificity, making glomeruli the basic unit for initial processing of odorant information. De...

journal_title：Chemical senses

authors： Lipscomb BW,Tolbert LP

更新日期：2006-03-01 00:00:00

abstract：:Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...

journal_title：Chemical senses

authors： Veldhuizen MG

更新日期：2017-10-31 00:00:00

abstract：:The sweet taste of sucrose acts as an analgesic, whereas the taste of a bitter substance decreases pain tolerance. The present experiment explores the analgesic effect of a complex taste and asks how adding cocoa, a substance often associated with sweet foods but that has a bitter taste, to a sucrose solution affects ...

journal_title：Chemical senses

authors： Eggleston K,White TL,Sheehe PR

更新日期：2010-05-01 00:00:00

abstract：:Previous studies have reported that the umami taste of monosodium l-glutamate (MSG) and salty-smelling odors (e.g., soy sauce, bacon, sardines) enhance the perception of saltiness. This study aimed to investigate the neural basis of the enhancement of saltiness in human participants using functional near-infrared spec...

journal_title：Chemical senses

authors： Onuma T,Maruyama H,Sakai N

更新日期：2018-02-26 00:00:00

abstract：:Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

journal_title：Chemical senses

authors： Lovelace CT,Slotnick BM

更新日期：1995-04-01 00:00:00

abstract：:Cnidarians are the simplest metazoans to exhibit satiety after feeding. When hydra are fed to repletion, they close their mouths and cease to capture prey. As feeding stops, contractions of the tentacles and body column increase. Our earlier experiments showed that a gel chromatographic fraction of prey substances inh...

journal_title：Chemical senses

authors： Grosvenor W,Rhoads DE,Kass-Simon G

更新日期：1996-06-01 00:00:00