A method for the rapid automated assessment of olfactory function.

abstract：:The suitability of Beidler's mixture equation for mixtures of sucrose and maltitol as well as for mixtures of sucrose and aspartame was examined in the presence of an orange aroma. The mean scores for the attribute sweet remained constant for each combination of sucrose and maltitol and for each combination of sucrose...

journal_title：Chemical senses

authors： Nahon DF,Roozen JP,de Graaf C

更新日期：1998-02-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:Two experiments examined time/concentration trading for the detection of carbon dioxide, an irritant with little or no odor. Experiment 1 employed the nasal lateralization method: subjects attempted to determine which nostril received carbon dioxide and which received pure air when presented simultaneously. Experiment...

journal_title：Chemical senses

authors： Wise PM,Radil T,Wysocki CJ

更新日期：2004-02-01 00:00:00

abstract：:Brazzein, a 54 residue sweet-tasting protein, is thought to participate in a multipoint binding interaction with the sweet taste receptor. Proposed sites for interaction with the receptor include 2 surface loops and the disulfide bond that connects the N- and C-termini. However, the importance of each site is not well...

journal_title：Chemical senses

authors： Dittli SM,Rao H,Tonelli M,Quijada J,Markley JL,Max M,Assadi-Porter F,Maillet E

更新日期：2011-11-01 00:00:00

abstract：:Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...

journal_title：Chemical senses

authors： Veldhuizen MG

更新日期：2017-10-31 00:00:00

abstract：:The present study demonstrated that 100 microM amiloride serves as an ineffective conditioned taste stimulus in a taste aversion paradigm. Even if amiloride has a detectable taste, it's unlikely that its behavioral effects in salt mixture experiments are due to its inherent taste quality. ...

journal_title：Chemical senses

authors： Markison S,Spector AC

更新日期：1995-10-01 00:00:00

abstract：:The mammalian olfactory system can discriminate between volatile molecules with subtle differences in their molecular structures. Efforts in synthetic chemistry have delivered a myriad of smelling compounds of different qualities as well as many molecules with very similar olfactive properties. One important class of ...

journal_title：Chemical senses

authors： Bieri S,Monastyrskaia K,Schilling B

更新日期：2004-07-01 00:00:00

abstract：:We are proposing that the "relative" abundances of the differently tuned pheromone-component-responsive olfactory receptor neurons (ORNs) on insect antennae are not a result of natural selection working to maximize absolute sensitivity to individual pheromone components. Rather, relative abundances are a result of spe...

journal_title：Chemical senses

authors： Baker TC,Domingue MJ,Myrick AJ

更新日期：2012-05-01 00:00:00

abstract：:Differences between elderly subjects (n = 46, 61-86 years) and young subjects (n = 36, 18-25 years) in food perception and food liking were investigated. Intensity and liking ratings were assessed for custard dessert, in which flavor enrichment, textural change, and irritant addition were incorporated as strategies to...

journal_title：Chemical senses

authors： Kremer S,Bult JH,Mojet J,Kroeze JH

更新日期：2007-07-01 00:00:00

abstract：:Anosmia affects the western world population, mostly the elderly, reaching to 5% in subjects over the age of 45 years and strongly lowering their quality of life. A smaller minority (about 0.01%) is born without a sense of smell, afflicted with congenital general anosmia (CGA). No causative genes for human CGA have be...

journal_title：Chemical senses

authors： Feldmesser E,Bercovich D,Avidan N,Halbertal S,Haim L,Gross-Isseroff R,Goshen S,Lancet D

更新日期：2007-01-01 00:00:00

abstract：:Flavor and texture contribute to the perception of creaminess in dairy products, but the nature of this interaction is not well understood. Previous studies on the genetic ability to perceive the bitter compound 6-n-propylthiouracil (PROP) reveal the existence of individual differences in creaminess perception. The ob...

journal_title：Chemical senses

authors： Kirkmeyer SV,Tepper BJ

更新日期：2003-07-01 00:00:00

abstract：:The effect of color on orthonasal and retronasal odor intensities was investigated. When odorants were smelled orthonasally (i.e., through the nostrils), color enhanced odor intensity ratings, consistent with previous reports. However, when odorants were smelled retronasally (i.e., the odorous solution was put in the ...

journal_title：Chemical senses

authors： Koza BJ,Cilmi A,Dolese M,Zellner DA

更新日期：2005-10-01 00:00:00

abstract：:When the glossopharyngeal (GP) nerve of the frog was stimulated electrically, electropositive slow potentials were recorded from the tongue surface and depolarizing slow potentials from taste cells in the fungiform papillae. The amplitude of the slow potentials was stimulus strength- and the frequency-dependent. Gener...

journal_title：Chemical senses

authors： Sato T,Toda K,Miyamoto T,Okada Y,Fujiyama R

更新日期：2000-10-01 00:00:00

abstract：:In social insects, recognition of nestmates from aliens is based on olfactory cues, and many studies have demonstrated that such cues are contained within the lipid layer covering the insect cuticle. These lipids are usually a complex mixture of tens of compounds in which aliphatic hydrocarbons are generally the major...

journal_title：Chemical senses

authors： Dani FR,Jones GR,Corsi S,Beard R,Pradella D,Turillazzi S

更新日期：2005-07-01 00:00:00

abstract：:Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally (IP) into C57BL/6 mi...

journal_title：Chemical senses

authors： Peng WH,Chau YP,Lu KS,Kung HN

更新日期：2016-01-01 00:00:00

abstract：:Response accuracy and odor-sampling times were used to compare the ability of mice to detect (+)-carvone and (+)-terpinen-4-ol and to discriminate between enantiomers of carvone and of terpinen-4-ol. Except for increased odor sampling when mice were first exposed to the (+)-carvone odor, there was no difference in odo...

journal_title：Chemical senses

authors： Slotnick B

更新日期：2007-09-01 00:00:00

abstract：:The vomeronasal organ (VNO) is important for activating accessory olfactory pathways that are involved in sexually dimorphic mating behavior. The VNO of male garter snakes is critically important for detection of, and response to, female sex pheromones. In the present study, under voltage-clamp conditions, male snake ...

journal_title：Chemical senses

authors： Huang GZ,Zhang JJ,Wang D,Mason RT,Halpern M

更新日期：2006-07-01 00:00:00

abstract：:Our study was designed to examine how components of complex mixtures can inhibit the binding of other components to receptor sites in the olfactory system of the spiny lobster Panulirus argus. Biochemical binding assays were used to study how two- to six-component mixtures inhibit binding of the radiolabeled odorants ...

journal_title：Chemical senses

authors： Gentilcore LR,Derby CD

更新日期：1998-06-01 00:00:00

abstract：:To assess the feasibility of using odors as a potential mechanism for treating sleep apnea, we set out to test the hypothesis that odorants delivered during sleep would modify respiratory patterns without inducing arousal or wake in healthy sleepers. We used 2 mildly trigeminal odorants: the pleasant lavender and unpl...

journal_title：Chemical senses

authors： Arzi A,Sela L,Green A,Givaty G,Dagan Y,Sobel N

更新日期：2010-01-01 00:00:00

abstract：:Many previous studies have attempted to investigate the effect of visual cues on olfactory perception in humans. The majority of this research has only looked at the modulatory effect of color, which has typically been explained in terms of multisensory perceptual interactions. However, such crossmodal effects may equ...

journal_title：Chemical senses

authors： Demattè ML,Sanabria D,Spence C

更新日期：2009-02-01 00:00:00

abstract：:Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

journal_title：Chemical senses

authors： Kotrschal K,Krautgartner WD,Hansen A

更新日期：1997-04-01 00:00:00

abstract：:It is difficult to determine the reason why a patient complains of a bitter taste when their mouth is empty. We examined a new diagnostic test using a bitterness masking substance. The bitterness masking substance, 'Benecoat BMI-60' (hereafter BMI-60), is a masking substance specific to the taste cells' bitterness rec...

journal_title：Chemical senses

authors： Ishimaru T,Hatanaka S,Miwa T,Furukawa M

更新日期：2001-01-01 00:00:00

abstract：:We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than wild-type brazzein. ...

journal_title：Chemical senses

authors： Walters DE,Cragin T,Jin Z,Rumbley JN,Hellekant G

更新日期：2009-10-01 00:00:00

abstract：:Olfactory receptor neurons (ORNs) in the antenna of insects serve to encode odors in action potential activity conducted to the olfactory lobe of the deuterocerebrum. We performed an analysis of the electrophysiological responses of olfactory neurons in the antennae of the female malaria mosquito Anopheles gambiae s.s...

journal_title：Chemical senses

authors： Qiu YT,van Loon JJ,Takken W,Meijerink J,Smid HM

更新日期：2006-11-01 00:00:00

abstract：:The importance of stimulus timing and location on the perceptual integration of taste and odour was studied based on a sub-threshold methodology. From a panel of 16 people, 12 showed the integration effect previously reported while 4 showed no effect. The experiment was repeated using retronasal and orthonasal deliver...

journal_title：Chemical senses

authors： Pfeiffer JC,Hollowood TA,Hort J,Taylor AJ

更新日期：2005-09-01 00:00:00

abstract：:A list of 147 tetralin- and indan-like compounds was compiled from the literature for investigating the relationship between molecular structure and musk odor. Each compound in the data set was represented by 374 CODESSA and 970 TAE descriptors. A genetic algorithm (GA) for pattern recognition analysis was used to id...

journal_title：Chemical senses

authors： Lavine BK,White C,Mirjankar N,Sundling CM,Breneman CM

更新日期：2012-10-01 00:00:00

abstract：:To analyze the mechanisms of perception and processing of pheromonal signals in vitro, we previously developed a new culture system for vomeronasal receptor neurons (VRNs), referred to as the vomeronasal pocket (VN pocket). However, very few VRNs were found to express the olfactory marker protein (OMP) and to have pro...

journal_title：Chemical senses

authors： Moriya-Ito K,Osada T,Ishimatsu Y,Muramoto K,Kobayashi T,Ichikawa M

更新日期：2005-02-01 00:00:00

abstract：:Recognition of individuals or classes of individuals plays an important role in the communication systems of many mammals. The ability of otariid (i.e., fur seal and sea lion) females to locate and identify their offspring in colonies after returning from regular foraging trips is essential to successful pup rearing. ...

journal_title：Chemical senses

authors： Wierucka K,Barthes N,Pitcher BJ,Schaal B,Charrier I,Harcourt RG

更新日期：2019-03-11 00:00:00

abstract：:The primary olfactory centre, the antennal lobe of Heliothis virescens moths, contains 62 glomeruli which process plant odour information and four male-specific glomeruli which form the macroglomerular complex, involved in processing information about pheromone and interspecific signals. Using calcium imaging, we reco...

journal_title：Chemical senses

authors： Skiri HT,Galizia CG,Mustaparta H

更新日期：2004-03-01 00:00:00

abstract：:Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...

journal_title：Chemical senses

authors： Wang Q,Titlow WB,McClintock DA,Stromberg AJ,McClintock TS

更新日期：2017-10-01 00:00:00