Revisiting sugar-fat mixtures: sweetness and creaminess vary with phenotypic markers of oral sensation.

Abstract:

:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Seventy-nine subjects (43 males) reported the sweetness and creaminess of water or milk (skim, whole, heavy cream) varying in sucrose (0-20% w/v) on the general Labeled Magnitude Scale. Sweetness grew with sucrose concentration and when shifting from water to milk mixtures--the growth was greatest for those tasting PROP as most bitter. At higher sucrose levels, increasing fat blunted the PROP-sweet relationship, whereas at lower levels, the relationship was effectively eliminated. Perceived sweetness of the mixture exceeded that predicted from the sum of components at low sucrose concentrations (especially for those tasting PROP most bitter) but fell below predicted at high concentrations, irrespective of fat level. Creaminess increased greatly with fat level and somewhat with sucrose. Those tasting PROP most bitter perceived greater creaminess in the heavy cream across all sucrose levels. Perceived creaminess was somewhat lower than predicted, irrespective of PROP bitterness. The FP density generally showed similar effects as PROP on sweetness and creaminess, (but to a lesser degree) and revealed potential taste-somatosensory interactions in weakly sweet stimuli. These data support that taste phenotype affects the nature of enhancement or suppression of sweetness and creaminess in liquid fat/sugar mixtures. Taste phenotype effects on sweetness and creaminess likely involve differential taste, retronasal olfactory, and somatosensory contributions to these perceptual experiences.

journal_name

Chem Senses

journal_title

Chemical senses

authors

Hayes JE,Duffy VB

doi

10.1093/chemse/bjl050

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

225-36

issue

3

eissn

0379-864X

issn

1464-3553

pii

bjl050

journal_volume

32

pub_type

杂志文章
  • Measurement of sensitivity to olfactory flavor: application in a study of aging and dentures.

    abstract::Olfaction involves a dual sensory process for perceiving odors orthonasally (through the nostrils) and retronasally (through the mouth). This investigation entailed developing a measure of sensitivity to an odor delivered in an orally sampled food (orange flavoring in a sucrose-sweetened gelatin) and examining sensiti...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/24.6.671

    authors: Duffy VB,Cain WS,Ferris AM

    更新日期:1999-12-01 00:00:00

  • A candidate pheromone receptor and two odorant receptors of the hawkmoth Manduca sexta.

    abstract::In this study, we cloned and characterized three Manduca sexta odorant receptors (ORs). One receptor is a putative pheromone receptor expressed exclusively in a cell associated with male-specific type-I trichoid sensilla. We describe the results of real-time PCR (RT-PCR) and quantitative real-time PCR (qRT-PCR) experi...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjp002

    authors: Patch HM,Velarde RA,Walden KK,Robertson HM

    更新日期:2009-05-01 00:00:00

  • Making scents: dynamic olfactometry for threshold measurement.

    abstract::Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjp088

    authors: Schmidt R,Cain WS

    更新日期:2010-02-01 00:00:00

  • Color enhances orthonasal olfactory intensity and reduces retronasal olfactory intensity.

    abstract::The effect of color on orthonasal and retronasal odor intensities was investigated. When odorants were smelled orthonasally (i.e., through the nostrils), color enhanced odor intensity ratings, consistent with previous reports. However, when odorants were smelled retronasally (i.e., the odorous solution was put in the ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bji057

    authors: Koza BJ,Cilmi A,Dolese M,Zellner DA

    更新日期:2005-10-01 00:00:00

  • Electroolfactogram responses from organotypic cultures of the olfactory epithelium from postnatal mice.

    abstract::Organotypic cultures of the mouse olfactory epithelium connected to the olfactory bulb were obtained with the roller tube technique from postnatal mice aged between 13 and 66 days. To test the functionality of the cultures, we measured electroolfactograms (EOGs) at different days in vitro (DIV), up to 7 DIV, and we co...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjn007

    authors: Pinato G,Rievaj J,Pifferi S,Dibattista M,Masten L,Menini A

    更新日期:2008-04-01 00:00:00

  • Odor-evoked autobiographical memories: age and gender differences along the life span.

    abstract::Odors are powerful in bringing back old and vivid memories bearing emotional content. This inherent hedonic property of olfactory stimuli makes this sensory modality particularly suitable for studying autobiographical memory. In the present work, adolescents (first experiment), young adults (second experiment), and el...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjr089

    authors: Zucco GM,Aiello L,Turuani L,Köster E

    更新日期:2012-02-01 00:00:00

  • Memory for brief, widely spaced odor presentations in the rat.

    abstract::Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.2.183

    authors: Lovelace CT,Slotnick BM

    更新日期:1995-04-01 00:00:00

  • A flux capacitor for moth pheromones.

    abstract::In this issue of Chemical Senses, Baker et al. propose a provocative and intriguing explanation for a commonly observed phenomenon in moth chemocommunication. Sex pheromones in moths typically consist of mixtures of long-chain unsaturated compounds in specific ratios. These ratios are correspondingly detected by male ...

    journal_title:Chemical senses

    pub_type: 评论,杂志文章

    doi:10.1093/chemse/bjs007

    authors: Olsson SB,Hansson BS

    更新日期:2012-05-01 00:00:00

  • Histochemical identification of carbohydrate moieties in the accessory olfactory bulb of the mouse using a panel of lectins.

    abstract::Lectin binding patterns in the olfactory bulb of the mouse were investigated using 12 biotinylated lectins. Three, with specificities for galactose, N-acetylgalactosamine and L-fucose, stained only the nervous and glomerular layers of the accessory olfactory bulb; four, with specificities for galactose or N-acetylgluc...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/26.6.645

    authors: Salazar I,Sánchez Quinteiro P,Lombardero M,Cifuentes JM

    更新日期:2001-07-01 00:00:00

  • Distortion of olfactory perception: diagnosis and treatment.

    abstract::Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/27.7.611

    authors: Leopold D

    更新日期:2002-09-01 00:00:00

  • Bimodal (taste/tactile) fibers innervate the maxillary barbel in the channel catfish.

    abstract::Analysis of single fibers isolated from a branch of the facial/trigeminal complex innervating the maxillary barbel of the channel catfish, Ictalurus punctatus, indicated the existence of bimodal (taste/tactile) fibers. Of the 60 single fibers recorded, 14 (23%) responded to both taste (amino acid) and tactile stimulat...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/22.4.477

    authors: Ogawa K,Marui T,Caprio J

    更新日期:1997-08-01 00:00:00

  • Role of Endocannabinoids on Sweet Taste Perception, Food Preference, and Obesity-related Disorders.

    abstract::The prevalence of obesity and obesity-related disorders such as type 2 diabetes (T2D) and metabolic syndrome has increased significantly in the past decades, reaching epidemic levels and therefore becoming a major health issue worldwide. Chronic overeating of highly palatable foods is one of the main responsible aspec...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjx062

    authors: Tarragon E,Moreno JJ

    更新日期:2017-12-25 00:00:00

  • Metabolic and Sensory Influences on Odor Sensitivity in Humans.

    abstract::Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to indu...

    journal_title:Chemical senses

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/chemse/bjv068

    authors: Ramaekers MG,Verhoef A,Gort G,Luning PA,Boesveldt S

    更新日期:2016-02-01 00:00:00

  • Selective inhibition of sweetness by the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid.

    abstract::The purpose of this study was to determine the degree to which the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid (Na-PMP) reduced sweet intensity ratings of 15 sweeteners in mixtures. Na-PMP has been approved for use in confectionary/frostings, soft candy and snack products in the USA at concentrations up to 15...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/24.4.439

    authors: Schiffman SS,Booth BJ,Sattely-Miller EA,Graham BG,Gibes KM

    更新日期:1999-08-01 00:00:00

  • Individual differences in sour and salt sensitivity: detection and quality recognition thresholds for citric acid and sodium chloride.

    abstract::Taste sensitivity is assessed with various techniques, including absolute detection and quality recognition. For any stimulus, one might expect individual differences in sensitivity to be reflected in all measures, but they are often surprisingly independent. Here, we focus on sensitivity to sour and salty taste, in p...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjt003

    authors: Wise PM,Breslin PA

    更新日期:2013-05-01 00:00:00

  • Porcine VEG proteins and tear prealbumins.

    abstract::Small soluble proteins, belonging to the lipocalin family are secreted in large amounts by tongue von Ebner's glands and lachrymal glands. In humans, the lingual protein, called VEG, and the lachrymal protein, called tear prealbumin, have shown identical cDNA sequences. In the pig, we have purified homodimeric protein...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.1.69

    authors: Garibotti M,Christiansen H,Schmale H,Pelosi P

    更新日期:1995-02-01 00:00:00

  • Understanding the regulation and function of adult neurogenesis: contribution from an insect model, the house cricket.

    abstract::Since the discovery of adult neurogenesis, a major issue is the role of newborn neurons and the function-dependent regulation of adult neurogenesis. We decided to use an animal model with a relatively simple brain to address these questions. In the adult cricket brain as in mammals, new neurons are produced throughout...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjm010

    authors: Cayre M,Scotto-Lomassese S,Malaterre J,Strambi C,Strambi A

    更新日期:2007-05-01 00:00:00

  • Working range of stimulus flux transduction determines dendrite size and relative number of pheromone component receptor neurons in moths.

    abstract::We are proposing that the "relative" abundances of the differently tuned pheromone-component-responsive olfactory receptor neurons (ORNs) on insect antennae are not a result of natural selection working to maximize absolute sensitivity to individual pheromone components. Rather, relative abundances are a result of spe...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjr122

    authors: Baker TC,Domingue MJ,Myrick AJ

    更新日期:2012-05-01 00:00:00

  • Maturation of vomeronasal receptor neurons in vitro by coculture with accessory olfactory bulb neurons.

    abstract::To analyze the mechanisms of perception and processing of pheromonal signals in vitro, we previously developed a new culture system for vomeronasal receptor neurons (VRNs), referred to as the vomeronasal pocket (VN pocket). However, very few VRNs were found to express the olfactory marker protein (OMP) and to have pro...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bji006

    authors: Moriya-Ito K,Osada T,Ishimatsu Y,Muramoto K,Kobayashi T,Ichikawa M

    更新日期:2005-02-01 00:00:00

  • Chemoreceptive control of feeding processes in hydra.

    abstract::Cnidarians are the simplest metazoans to exhibit satiety after feeding. When hydra are fed to repletion, they close their mouths and cease to capture prey. As feeding stops, contractions of the tentacles and body column increase. Our earlier experiments showed that a gel chromatographic fraction of prey substances inh...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.3.313

    authors: Grosvenor W,Rhoads DE,Kass-Simon G

    更新日期:1996-06-01 00:00:00

  • A sexually dimorphic group of atypical glomeruli in the mouse olfactory bulb.

    abstract::Atypical glomeruli (AtG) are clearly distinguishable from typical ones because of their strong cholinergic innervation. AtG are located in defined positions in the caudal half of the main olfactory bulb of rodents. The AtG partially overlap with other specialized olfactory subsystems, such as the modified glomerular c...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/26.1.7

    authors: Weruaga E,Briñón JG,Porteros A,Arévalo R,Aijón J,Alonso JR

    更新日期:2001-01-01 00:00:00

  • Individual comparisons of the levels of (E)-3-methyl-2-hexenoic acid, an axillary odor-related compound, in Japanese.

    abstract::The (E)-3-methyl-2-hexenoic acid (E3M2H), an axillary odor-related compound, is known to occur in Caucasians. The aims of this study were to clarify whether E3M2H contributes to axillary odor in Asians and to quantify and compare individual levels of E3M2H. Quantitative determination of E3M2H was performed by means of...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjj060

    authors: Akutsu T,Sekiguchi K,Ohmori T,Sakurada K

    更新日期:2006-07-01 00:00:00

  • Individual Differences in Verbal and Non-Verbal Affective Responses to Smells: Influence of Odor Label Across Cultures.

    abstract::Olfactory perception is highly variable from one person to another, as a function of individual and contextual factors. Here, we investigated the influence of 2 important factors of variation: culture and semantic information. More specifically, we tested whether cultural-specific knowledge and presence versus absence...

    journal_title:Chemical senses

    pub_type: 临床试验,杂志文章

    doi:10.1093/chemse/bjw098

    authors: Ferdenzi C,Joussain P,Digard B,Luneau L,Djordjevic J,Bensafi M

    更新日期:2017-01-01 00:00:00

  • Respiratory modulation of olfactory neurons in the rodent brain.

    abstract::In this review we report data from freely breathing animals in an attempt to show how respiratory dynamics can influence bulbar and cortical activity. Relying on in vivo data as well as in vitro observations, we try to emphasize the multiple mechanisms that underlie this modulation, its multiple origins, and its possi...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjj010

    authors: Buonviso N,Amat C,Litaudon P

    更新日期:2006-02-01 00:00:00

  • A method for the rapid automated assessment of olfactory function.

    abstract::We have developed a strategy for the rapid high-throughput screening of odor responsivity in genetically altered mice (in fact, any experimentally altered animal). Specifically, the report presents the development and validation of a fully automated procedure based on the evaluation of an animal's stimulus-induced ref...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bji017

    authors: Youngentob SL

    更新日期:2005-03-01 00:00:00

  • The influence of odorants on respiratory patterns in sleep.

    abstract::To assess the feasibility of using odors as a potential mechanism for treating sleep apnea, we set out to test the hypothesis that odorants delivered during sleep would modify respiratory patterns without inducing arousal or wake in healthy sleepers. We used 2 mildly trigeminal odorants: the pleasant lavender and unpl...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjp079

    authors: Arzi A,Sela L,Green A,Givaty G,Dagan Y,Sobel N

    更新日期:2010-01-01 00:00:00

  • A new method to improve olfactory responses to GC effluents.

    abstract::Biological detectors such as the human nose or an insect antenna represent extremely attractive detectors for gas chromatography (GC) since they are specifically tuned to perceive biologically relevant compounds. However, these detectors are nonlinear, noisy and often perform poorly under standard GC conditions since ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/23.6.647

    authors: Gouinguené S,de Cruz I,van der Pers J,Wadhams L,Marion-Poll F

    更新日期:1998-12-01 00:00:00

  • Anosmia-A Clinical Review.

    abstract::Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjx025

    authors: Boesveldt S,Postma EM,Boak D,Welge-Luessen A,Schöpf V,Mainland JD,Martens J,Ngai J,Duffy VB

    更新日期:2017-09-01 00:00:00

  • Temporal integration in nasal lateralization and nasal detection of carbon dioxide.

    abstract::Two experiments examined time/concentration trading for the detection of carbon dioxide, an irritant with little or no odor. Experiment 1 employed the nasal lateralization method: subjects attempted to determine which nostril received carbon dioxide and which received pure air when presented simultaneously. Experiment...

    journal_title:Chemical senses

    pub_type: 临床试验,杂志文章

    doi:10.1093/chemse/bjh018

    authors: Wise PM,Radil T,Wysocki CJ

    更新日期:2004-02-01 00:00:00

  • Odor detection by humans of lineal aliphatic aldehydes and helional as gauged by dose-response functions.

    abstract::We have measured concentration detection (i.e., psychometric) functions to determine the odor detectability of homologous aliphatic aldehydes (propanal, butanal, hexanal, octanal, and nonanal) and helional. Subjects (16 < or = n < or = 18) used a 3-alternative forced-choice procedure against carbon-filtered air (blank...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjq018

    authors: Cometto-Muñiz JE,Abraham MH

    更新日期:2010-05-01 00:00:00