Respiratory modulation of olfactory neurons in the rodent brain.

abstract：:To assess the feasibility of using odors as a potential mechanism for treating sleep apnea, we set out to test the hypothesis that odorants delivered during sleep would modify respiratory patterns without inducing arousal or wake in healthy sleepers. We used 2 mildly trigeminal odorants: the pleasant lavender and unpl...

journal_title：Chemical senses

authors： Arzi A,Sela L,Green A,Givaty G,Dagan Y,Sobel N

更新日期：2010-01-01 00:00:00

abstract：:Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...

journal_title：Chemical senses

authors： Leopold D

更新日期：2002-09-01 00:00:00

abstract：:Extracellular neuronal responses were recorded from the posterior insular cortex following electrical and chemical stimulation of the thalamic reticular nucleus (Rt) regions. In the present study, most neurons (29/32) were first characterized for their responses to electrical stimulation of the superior laryngeal (SL)...

journal_title：Chemical senses

authors： Hanamori T

更新日期：2003-10-01 00:00:00

abstract：:The reported effects of temperature on sweet taste in humans have generally been small and inconsistent. Here, we describe 3 experiments that follow up a recent finding that cooling from 37 to 21 °C does not reduce the initial sweetness of sucrose but increases sweet taste adaptation. In experiment 1, subjects rated t...

journal_title：Chemical senses

authors： Green BG,Nachtigal D

更新日期：2015-07-01 00:00:00

abstract：:Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...

journal_title：Chemical senses

authors： Schwartz C,Chabanet C,Szleper E,Feyen V,Issanchou S,Nicklaus S

更新日期：2017-09-01 00:00:00

abstract：:The state of the art in aroma analysis is reviewed with emphasis on aroma-recombination studies using synthetic blends of odorants (aroma models) which have been prepared on the basis of analytical data. The model that matches the original aroma is the starting material for omission experiments which are performed to ...

journal_title：Chemical senses

authors： Grosch W

更新日期：2001-06-01 00:00:00

abstract：:Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...

journal_title：Chemical senses

authors： Boesveldt S,Postma EM,Boak D,Welge-Luessen A,Schöpf V,Mainland JD,Martens J,Ngai J,Duffy VB

更新日期：2017-09-01 00:00:00

abstract：:In acipenserids, crypt cells (CCs) have only been observed in juvenile specimens, and it has not been clarified whether they differentiate along with olfactory receptor neurons (ORNs) during the lecithotrophic stage or during later development stages. Furthermore, no detailed optical microscopy (OM) or electron micros...

journal_title：Chemical senses

authors： Camacho S,Ostos-Garrido MV,Domezain A,Carmona R

更新日期：2010-02-01 00:00:00

abstract：:Restriction of dietary sodium during gestation has major effects on taste function and anatomy in the offspring. The chorda tympani nerve of offspring that are maintained on sodium-reduced chow throughout life (NaDep) has reduced neurophysiological responses to sodium and altered morphology of its terminal field in th...

journal_title：Chemical senses

authors： Sollars SI,Hill DL

更新日期：2000-12-01 00:00:00

abstract：:We have measured concentration detection (i.e., psychometric) functions to determine the odor detectability of homologous aliphatic aldehydes (propanal, butanal, hexanal, octanal, and nonanal) and helional. Subjects (16 < or = n < or = 18) used a 3-alternative forced-choice procedure against carbon-filtered air (blank...

journal_title：Chemical senses

authors： Cometto-Muñiz JE,Abraham MH

更新日期：2010-05-01 00:00:00

abstract：:In order to study potential mixture interactions among bitter compounds, selected sodium salts were added to five compounds presented either alone or as binary bitter-compound mixtures. Each compound was tested at a concentration that elicited 'weak' perceived bitterness. The bitter compounds were mixed at these conce...

journal_title：Chemical senses

authors： Keast RS,Canty TM,Breslin PA

更新日期：2004-06-01 00:00:00

abstract：:Three experiments assessed potential changes in the rat's perception of sodium chloride (NaCl) during a state of sodium appetite. In Experiment 1, sodium-sufficient rats licking a range of NaCl concentrations (0.028-0.89M) in 15s trials showed an inverted U-shaped concentration response function peaking at 0.281M. Dep...

journal_title：Chemical senses

authors： St John SJ

更新日期：2017-02-01 00:00:00

abstract：:Response accuracy and odor-sampling times were used to compare the ability of mice to detect (+)-carvone and (+)-terpinen-4-ol and to discriminate between enantiomers of carvone and of terpinen-4-ol. Except for increased odor sampling when mice were first exposed to the (+)-carvone odor, there was no difference in odo...

journal_title：Chemical senses

authors： Slotnick B

更新日期：2007-09-01 00:00:00

abstract：:The distribution of NADPH-diaphroase activity was examined in the accessory olfactory bulb of the rat using a direct histochemical technique. Labeled fibers and somata were found in all layers of the accessory olfactory bulb. The entire vomeronasal nerve and all vomeronasal glomeruli were strongly labeled, contrary to...

journal_title：Chemical senses

authors： Porteros A,Alonso JR,Arévalo R,García-Ojeda E,Crespo C,Aijón J

更新日期：1994-10-01 00:00:00

abstract：:Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...

journal_title：Chemical senses

authors： Harder DB,Gannon KS,Whitney G

更新日期：1996-10-01 00:00:00

abstract：:Two experiments, using different ranges and numbers of stimuli, examined how linguistic labels affect the identification of flavor mixtures containing different proportions of sucrose (gustatory flavorant) and citral (olfactory flavorant). Both experiments asked subjects to identify each stimulus as having either "mos...

journal_title：Chemical senses

authors： Brewer JM,Shavit AY,Shepard TG,Veldhuizen MG,Parikh R,Marks LE

更新日期：2013-05-01 00:00:00

abstract：:Analysis of single fibers isolated from a branch of the facial/trigeminal complex innervating the maxillary barbel of the channel catfish, Ictalurus punctatus, indicated the existence of bimodal (taste/tactile) fibers. Of the 60 single fibers recorded, 14 (23%) responded to both taste (amino acid) and tactile stimulat...

journal_title：Chemical senses

authors： Ogawa K,Marui T,Caprio J

更新日期：1997-08-01 00:00:00

abstract：:Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight ...

journal_title：Chemical senses

authors： Proserpio C,Laureati M,Bertoli S,Battezzati A,Pagliarini E

更新日期：2016-02-01 00:00:00

abstract：:We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than wild-type brazzein. ...

journal_title：Chemical senses

authors： Walters DE,Cragin T,Jin Z,Rumbley JN,Hellekant G

更新日期：2009-10-01 00:00:00

abstract：:Olfaction involves a dual sensory process for perceiving odors orthonasally (through the nostrils) and retronasally (through the mouth). This investigation entailed developing a measure of sensitivity to an odor delivered in an orally sampled food (orange flavoring in a sucrose-sweetened gelatin) and examining sensiti...

journal_title：Chemical senses

authors： Duffy VB,Cain WS,Ferris AM

更新日期：1999-12-01 00:00:00

abstract：:The strong bond that is formed between ewe and lamb after parturition is important for lamb survival. Evidence exists that the ewe mainly employs olfactory recognition cues to distinguish her lamb from other lambs in the flock. We have found that volatile organic compounds in the wool of Merino lambs that presumably c...

journal_title：Chemical senses

authors： Viviers MZ,Burger BV,le Roux NJ,Morris J,le Roux M

更新日期：2014-03-01 00:00:00

abstract：:Different odorant-binding proteins (OBPs) were isolated from total antennal homogenates of male and female Bombyx mori. Proteins were separated according to their isoelectric point by using preparative fast-flow isoelectrofocusing. Odorant-binding proteins were identified in immunoblots by antisera raised against the ...

journal_title：Chemical senses

authors： Maida R,Proebstl T,Laue M

更新日期：1997-10-01 00:00:00

abstract：:The central projections of olfactory receptor cells associated with two distinct types of antennal sensilla in the sphinx moth Manduca sexta were revealed by anterograde staining. In both sexes, receptor axons that arise from sexually isomorphic, type-II trichoid sensilla (and possibly some basiconic sensilla) project...

journal_title：Chemical senses

authors： Christensen TA,Harrow ID,Cuzzocrea C,Randolph PW,Hildebrand JG

更新日期：1995-06-01 00:00:00

abstract：:The effects of the membrane-permeable dibutyryl guanosine 3', 5'-cyclic monophosphate (db-cGMP) on the bombykol-elicited receptor current and nerve impulse activity were studied using the open sensillum recording technique. db-cGMP was applied to the outer dendritic membrane of the olfactory receptor neuron of the mot...

journal_title：Chemical senses

authors： Redkozubov A

更新日期：2000-08-01 00:00:00

abstract：:The embryonic origins of taste receptor cells have not been established experimentally. Although related receptor cells (e.g. hair cells of the inner ear, lateral line receptors) are known to arise from neurogenic ectoderm (e.g. neural crest or placodes), taste buds are described as arising from local epithelial cells...

journal_title：Chemical senses

authors： Stone LM,Finger TE

更新日期：1994-12-01 00:00:00

abstract：:Experience is an essential factor informing food choice. Eating food generates enduring odor-taste associations that link an odor with a taste's quality and hedonic value (pleasantness/unpleasantness) and creates the perception of a congruent odor-taste combination. Previous human psychophysical experiments demonstrat...

journal_title：Chemical senses

authors： McQueen KA,Fredericksen KE,Samuelsen CL

更新日期：2020-05-29 00:00:00

abstract：:Cnidarians are the simplest metazoans to exhibit satiety after feeding. When hydra are fed to repletion, they close their mouths and cease to capture prey. As feeding stops, contractions of the tentacles and body column increase. Our earlier experiments showed that a gel chromatographic fraction of prey substances inh...

journal_title：Chemical senses

authors： Grosvenor W,Rhoads DE,Kass-Simon G

更新日期：1996-06-01 00:00:00

abstract：:Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC...

journal_title：Chemical senses

authors： Wooding SP

更新日期：2018-08-24 00:00:00

abstract：:In 20 normal and four anosmic participants, instantaneous inhalation and exhalation flow rates were recorded in response to 15 s stimulations with clean air or propionic acid concentrations (0.16, 1.14, 8.22 and 59.15 p.p.m., v/v) that ranged from peri-threshold for normals to clearly supra-threshold for anosmics. Eac...

journal_title：Chemical senses

authors： Walker JC,Kendal-Reed M,Hall SB,Morgan WT,Polyakov VV,Lutz RW

更新日期：2001-05-01 00:00:00

abstract：:Two experiments examined time/concentration trading for the detection of carbon dioxide, an irritant with little or no odor. Experiment 1 employed the nasal lateralization method: subjects attempted to determine which nostril received carbon dioxide and which received pure air when presented simultaneously. Experiment...

journal_title：Chemical senses

authors： Wise PM,Radil T,Wysocki CJ

更新日期：2004-02-01 00:00:00