Bitter Fruit: Inverse Associations Between PTC and Antidesma bunius Perception.

Abstract:

:Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC? New evidence supports speculation that it is indeed functional. Associations between TAS2R38 mutations and bitter sensitivity to the tropical berry Antidesma bunius are the inverse of those PTC, suggesting that the non-taster allele enables perception to compounds in the fruit.

journal_name

Chem Senses

journal_title

Chemical senses

authors

Wooding SP

doi

10.1093/chemse/bjy044

subject

Has Abstract

pub_date

2018-08-24 00:00:00

pages

447-450

issue

7

eissn

0379-864X

issn

1464-3553

pii

5049605

journal_volume

43

pub_type

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