Abstract:
:It is difficult to determine the reason why a patient complains of a bitter taste when their mouth is empty. We examined a new diagnostic test using a bitterness masking substance. The bitterness masking substance, 'Benecoat BMI-60' (hereafter BMI-60), is a masking substance specific to the taste cells' bitterness receptors. After patients gargled with BMI-60 solutions, the phantom sensation of bitterness was masked in some patients, but was not masked in others. Bitter substances in saliva seemed to be masked by BMI-60, but bitterness did not seem to be masked when the locus of the phantom sensation was within the peripheral nerve and/or the brain. The bitterness masking test is useful for diagnosis of the phantom sensation of bitter taste.
journal_name
Chem Sensesjournal_title
Chemical sensesauthors
Ishimaru T,Hatanaka S,Miwa T,Furukawa Mdoi
10.1093/chemse/26.1.91keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
91-3issue
1eissn
0379-864Xissn
1464-3553journal_volume
26pub_type
杂志文章相关文献
CHEMICAL SENSES文献大全abstract::Experience is an essential factor informing food choice. Eating food generates enduring odor-taste associations that link an odor with a taste's quality and hedonic value (pleasantness/unpleasantness) and creates the perception of a congruent odor-taste combination. Previous human psychophysical experiments demonstrat...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjaa025
更新日期:2020-05-29 00:00:00
abstract::Organotypic cultures of the mouse olfactory epithelium connected to the olfactory bulb were obtained with the roller tube technique from postnatal mice aged between 13 and 66 days. To test the functionality of the cultures, we measured electroolfactograms (EOGs) at different days in vitro (DIV), up to 7 DIV, and we co...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjn007
更新日期:2008-04-01 00:00:00
abstract::Anosmia affects the western world population, mostly the elderly, reaching to 5% in subjects over the age of 45 years and strongly lowering their quality of life. A smaller minority (about 0.01%) is born without a sense of smell, afflicted with congenital general anosmia (CGA). No causative genes for human CGA have be...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjl032
更新日期:2007-01-01 00:00:00
abstract::We report 2 experiments designed to investigate the effect of people's prior beliefs concerning specific color-flavor associations on their ability to discriminate the flavor of colored sugar-coated chocolate sweets. The participants in our study judged whether pairs of Smarties had the same flavor or not. In our firs...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjn008
更新日期:2008-06-01 00:00:00
abstract::Taste sensitivity is assessed with various techniques, including absolute detection and quality recognition. For any stimulus, one might expect individual differences in sensitivity to be reflected in all measures, but they are often surprisingly independent. Here, we focus on sensitivity to sour and salty taste, in p...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjt003
更新日期:2013-05-01 00:00:00
abstract::The effects of the membrane-permeable dibutyryl guanosine 3', 5'-cyclic monophosphate (db-cGMP) on the bombykol-elicited receptor current and nerve impulse activity were studied using the open sensillum recording technique. db-cGMP was applied to the outer dendritic membrane of the olfactory receptor neuron of the mot...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.4.381
更新日期:2000-08-01 00:00:00
abstract::The role of Ca(2+) in insect olfactory transduction was studied in the moth Spodoptera littoralis. Single sensillum recordings were made to investigate in vivo the role of sensillar Ca(2+) on the electrophysiological properties of sex pheromone responsive olfactory receptor neurons (ORNs). Lowering the sensillar Ca(2+...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjl059
更新日期:2007-05-01 00:00:00
abstract::The septal organ of Masera (SO) is a small, isolated patch of olfactory epithelium, located in the ventral part of the nasal septum. We investigated in this systematic study the postnatal development of the SO in histological sections of rats at various ages from the day of birth (P1) to P666. The SO-area increases to...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjg047
更新日期:2003-09-01 00:00:00
abstract::Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to indu...
journal_title:Chemical senses
pub_type: 杂志文章,随机对照试验
doi:10.1093/chemse/bjv068
更新日期:2016-02-01 00:00:00
abstract::Many previous studies have attempted to investigate the effect of visual cues on olfactory perception in humans. The majority of this research has only looked at the modulatory effect of color, which has typically been explained in terms of multisensory perceptual interactions. However, such crossmodal effects may equ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjn055
更新日期:2009-02-01 00:00:00
abstract::In chum salmon captured at the coastal sea and the natal river, the magnitudes of the olfactory nerve responses to the amino acids after perfusion of the olfactory epithelium with artificial pond water (APW) were similar to those after perfusion with artificial sea water (ASW), although the concentrations of Na+, Cl- ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/19.6.609
更新日期:1994-12-01 00:00:00
abstract::In acipenserids, crypt cells (CCs) have only been observed in juvenile specimens, and it has not been clarified whether they differentiate along with olfactory receptor neurons (ORNs) during the lecithotrophic stage or during later development stages. Furthermore, no detailed optical microscopy (OM) or electron micros...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjp091
更新日期:2010-02-01 00:00:00
abstract::Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx025
更新日期:2017-09-01 00:00:00
abstract::Studies over the last 8 years have identified 3 potential channels that appear to release ATP from Type II cells in response to taste stimuli. These studies have taken different methodological approaches but have all provided data supporting their candidate channel as the ATP release channel. These potential channels ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv035
更新日期:2015-09-01 00:00:00
abstract::The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjx002
更新日期:2017-03-01 00:00:00
abstract::Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjl037
更新日期:2007-02-01 00:00:00
abstract::The antisense DNA method has been used successfully to block the expression of specific genes in vivo in neuronal systems. An increasing number of studies in the last few years have shown that antisense DNA administered directly into the brain can modify various kinds of behaviors. These findings strongly suggest that...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/23.2.249
更新日期:1998-04-01 00:00:00
abstract::Individual recognition has been studied across a number of taxa and modalities; however, few attempts have been made to combine chemical and biological approaches and arrive at a more complete understanding of the use of secretions as signals. We combined behavioral habituation experiments with gas chromatography-mass...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjr055
更新日期:2011-11-01 00:00:00
abstract::The effect of soluble starch (acid-modified starch) on taste intensity was investigated in human subjects. Different concentrations of sucrose (Suc), six sweeteners, NaCl, quinine-HCl (QHCl) and citric acid (Cit) were dissolved in either distilled water (DW; standard) or starch solution (test solution). The solutions ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/27.1.67
更新日期:2002-01-01 00:00:00
abstract::The objective of this study was to develop a semantically labeled hedonic scale (LHS) that would yield ratio-level data on the magnitude of liking/disliking of sensation equivalent to that produced by magnitude estimation (ME). The LHS was constructed by having 49 subjects who were trained in ME rate the semantic magn...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjp054
更新日期:2009-11-01 00:00:00
abstract::Two experiments examined time/concentration trading for the detection of carbon dioxide, an irritant with little or no odor. Experiment 1 employed the nasal lateralization method: subjects attempted to determine which nostril received carbon dioxide and which received pure air when presented simultaneously. Experiment...
journal_title:Chemical senses
pub_type: 临床试验,杂志文章
doi:10.1093/chemse/bjh018
更新日期:2004-02-01 00:00:00
abstract::In this review we report data from freely breathing animals in an attempt to show how respiratory dynamics can influence bulbar and cortical activity. Relying on in vivo data as well as in vitro observations, we try to emphasize the multiple mechanisms that underlie this modulation, its multiple origins, and its possi...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjj010
更新日期:2006-02-01 00:00:00
abstract::The primary olfactory centre, the antennal lobe of Heliothis virescens moths, contains 62 glomeruli which process plant odour information and four male-specific glomeruli which form the macroglomerular complex, involved in processing information about pheromone and interspecific signals. Using calcium imaging, we reco...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjh026
更新日期:2004-03-01 00:00:00
abstract::When the glossopharyngeal (GP) nerve of the frog was stimulated electrically, electropositive slow potentials were recorded from the tongue surface and depolarizing slow potentials from taste cells in the fungiform papillae. The amplitude of the slow potentials was stimulus strength- and the frequency-dependent. Gener...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.5.583
更新日期:2000-10-01 00:00:00
abstract::The aim of this study was to investigate the relationship of fungiform papillae density with taste detection thresholds for sucrose of young male adults. One hundred and eighty two subjects aged 18-23 years (mean age: 21.9 +/- 1.2 years) were included. The densities of fungiform papillae were recorded with the aid of ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjn059
更新日期:2009-01-01 00:00:00
abstract::Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy025
更新日期:2018-07-05 00:00:00
abstract::An odor emitted by an object signals the presence of that object and may draw attention to it. Can odors that are not actually emitted by an object also function as a signal? We investigated whether the degree of thematic congruency between an ambient odor and a magazine affected magazine sales in a retail store. We s...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/27.6.539
更新日期:2002-07-01 00:00:00
abstract::The perception of sweetness and flavour were studied in viscous solutions containing 50 g/l sucrose, 100 p.p.m. iso-amyl acetate and varying concentrations of three hydrocolloid thickeners (guar gum, lambda-carrageenan and hydroxypropylmethyl cellulose). Zero-shear viscosity of the samples ranged from 1 to 5000 mPas. ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/28.1.11
更新日期:2003-01-01 00:00:00
abstract::Despite long and intense research, some fundamental questions regarding representation of taste information in the brain still remain unanswered. This might in part be due to shortcomings of the established methods that limit the researcher either to thorough characterization of few elements or to analyze the response...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy017
更新日期:2018-04-23 00:00:00
abstract::During the past 2 decades, considerable progress has been made in the study of bird semiochemistry, and our goal was to review and evaluate this literature with particular emphasis on the volatile organic constituents. Indeed, since the importance of social chemosignaling in birds is becoming more and more apparent, t...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjr067
更新日期:2012-01-01 00:00:00