Mutations in olfactory signal transduction genes are not a major cause of human congenital general anosmia.

abstract：:Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...

journal_title：Chemical senses

authors： Harder DB,Gannon KS,Whitney G

更新日期：1996-10-01 00:00:00

abstract：:Differences between elderly subjects (n = 46, 61-86 years) and young subjects (n = 36, 18-25 years) in food perception and food liking were investigated. Intensity and liking ratings were assessed for custard dessert, in which flavor enrichment, textural change, and irritant addition were incorporated as strategies to...

journal_title：Chemical senses

authors： Kremer S,Bult JH,Mojet J,Kroeze JH

更新日期：2007-07-01 00:00:00

abstract：:Individual recognition has been studied across a number of taxa and modalities; however, few attempts have been made to combine chemical and biological approaches and arrive at a more complete understanding of the use of secretions as signals. We combined behavioral habituation experiments with gas chromatography-mass...

journal_title：Chemical senses

authors： Liu D,Huang KJ,Zhang JX

更新日期：2011-11-01 00:00:00

abstract：:Olfactory receptor neurons (ORNs) in the antenna of insects serve to encode odors in action potential activity conducted to the olfactory lobe of the deuterocerebrum. We performed an analysis of the electrophysiological responses of olfactory neurons in the antennae of the female malaria mosquito Anopheles gambiae s.s...

journal_title：Chemical senses

authors： Qiu YT,van Loon JJ,Takken W,Meijerink J,Smid HM

更新日期：2006-11-01 00:00:00

abstract：:The vomeronasal organ (VNO) is important for activating accessory olfactory pathways that are involved in sexually dimorphic mating behavior. The VNO of male garter snakes is critically important for detection of, and response to, female sex pheromones. In the present study, under voltage-clamp conditions, male snake ...

journal_title：Chemical senses

authors： Huang GZ,Zhang JJ,Wang D,Mason RT,Halpern M

更新日期：2006-07-01 00:00:00

abstract：:Recognition of individuals or classes of individuals plays an important role in the communication systems of many mammals. The ability of otariid (i.e., fur seal and sea lion) females to locate and identify their offspring in colonies after returning from regular foraging trips is essential to successful pup rearing. ...

journal_title：Chemical senses

authors： Wierucka K,Barthes N,Pitcher BJ,Schaal B,Charrier I,Harcourt RG

更新日期：2019-03-11 00:00:00

abstract：:In this study, we cloned and characterized three Manduca sexta odorant receptors (ORs). One receptor is a putative pheromone receptor expressed exclusively in a cell associated with male-specific type-I trichoid sensilla. We describe the results of real-time PCR (RT-PCR) and quantitative real-time PCR (qRT-PCR) experi...

journal_title：Chemical senses

authors： Patch HM,Velarde RA,Walden KK,Robertson HM

更新日期：2009-05-01 00:00:00

abstract：:Associative plasticity is a basic essential attribute of nervous systems. As shown by numerous reports, Drosophila is able to establish simple forms of appetitive and aversive olfactory associations at both larval and adult stages. Whereas most adult studies on aversive learning employed electric shock as a negative r...

journal_title：Chemical senses

authors： Pauls D,Pfitzenmaier JE,Krebs-Wheaton R,Selcho M,Stocker RF,Thum AS

更新日期：2010-05-01 00:00:00

abstract：:When one taste (masker) is strong enough, it can completely mask another task (target) of different quality. How strong the masker must be to do this depends on how strong the target is. As the target concentration is increased, the masking concentration must be increased, too, but in ever-increasing proportion. To qu...

journal_title：Chemical senses

authors： Stevens JC

更新日期：1996-04-01 00:00:00

abstract：:Pheromone-sensitive sensilla trichodea of nine moth species belonging to six families and three superfamilies of Lepidoptera were immunolabelled with an antiserum against the pheromone-binding protein of Antheraea polyphemus. Strong immunolabelling of the sensillum lymph was observed in all long sensilla trichodea of ...

journal_title：Chemical senses

authors： Steinbrecht RA

更新日期：1996-12-01 00:00:00

abstract：:Presynaptic inhibition is the suppression of neurotransmitter release from a neuron by inhibitory input onto its presynaptic terminal. In the olfactory system, the primary sensory afferents from the olfactory neuroepithelium to the brain's olfactory bulb are strongly modulated by a presynaptic inhibition that has been...

journal_title：Chemical senses

authors： McGann JP

更新日期：2013-07-01 00:00:00

abstract：:Response accuracy and odor-sampling times were used to compare the ability of mice to detect (+)-carvone and (+)-terpinen-4-ol and to discriminate between enantiomers of carvone and of terpinen-4-ol. Except for increased odor sampling when mice were first exposed to the (+)-carvone odor, there was no difference in odo...

journal_title：Chemical senses

authors： Slotnick B

更新日期：2007-09-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:Many rodents are now known to exhibit an obligate proteinuria that delivers urine-mediated chemosignals. In this paper, we explore the urinary proteins of the Roborovski hamster (Phodopus roborovskii). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of urine from individual male and female Roborovsk...

journal_title：Chemical senses

authors： Turton MJ,Robertson DH,Smith JR,Hurst JL,Beynon RJ

更新日期：2010-10-01 00:00:00

abstract：:The G protein subunit alpha-gustducin is expressed in a subset of light (Type II) but not in dark (Type I) cells in rat vallate taste buds. The thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) is incorporated into DNA during the S-phase of the cell cycle and can be used to determine the time of origin of a cell. In t...

journal_title：Chemical senses

authors： Cho YK,Farbman AI,Smith DV

更新日期：1998-12-01 00:00:00

abstract：:The state of the art in aroma analysis is reviewed with emphasis on aroma-recombination studies using synthetic blends of odorants (aroma models) which have been prepared on the basis of analytical data. The model that matches the original aroma is the starting material for omission experiments which are performed to ...

journal_title：Chemical senses

authors： Grosch W

更新日期：2001-06-01 00:00:00

abstract：:The stimuli used in taste research are usually considered to be odourless. This was tested in two experiments with aqueous solutions of two representative compounds for each of the five taste qualities including umami. In the first experiment elderly and young subjects rated the intensity and pleasantness of three con...

journal_title：Chemical senses

authors： Mojet J,Köster EP,Prinz JF

更新日期：2005-01-01 00:00:00

abstract：:Odorants and flavorants typically contain many components. It is generally easier to detect multicomponent stimuli than to detect a single component, through either neural integration or probability summation (PS) (or both). PS assumes that the sensory effects of 2 (or more) stimulus components (e.g., gustatory and ol...

journal_title：Chemical senses

authors： Marks LE,Veldhuizen MG,Shepard TG,Shavit AY

更新日期：2012-03-01 00:00:00

abstract：:Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...

journal_title：Chemical senses

authors： Veldhuizen MG

更新日期：2017-10-31 00:00:00

abstract：:The antisense DNA method has been used successfully to block the expression of specific genes in vivo in neuronal systems. An increasing number of studies in the last few years have shown that antisense DNA administered directly into the brain can modify various kinds of behaviors. These findings strongly suggest that...

journal_title：Chemical senses

authors： Ogawa S,Pfaff DW

更新日期：1998-04-01 00:00:00

abstract：:Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...

journal_title：Chemical senses

authors： Manoel D,Makhlouf M,Scialdone A,Saraiva LR

更新日期：2019-01-01 00:00:00

abstract：:Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

journal_title：Chemical senses

authors： Kotrschal K,Krautgartner WD,Hansen A

更新日期：1997-04-01 00:00:00

abstract：:To assess the feasibility of using odors as a potential mechanism for treating sleep apnea, we set out to test the hypothesis that odorants delivered during sleep would modify respiratory patterns without inducing arousal or wake in healthy sleepers. We used 2 mildly trigeminal odorants: the pleasant lavender and unpl...

journal_title：Chemical senses

authors： Arzi A,Sela L,Green A,Givaty G,Dagan Y,Sobel N

更新日期：2010-01-01 00:00:00

abstract：:Olfactory function assessment is an important screening tool and also may differentiate Parkinson's disease (PD) patients from other parkinsonisms, including nondegenerative ones, such as, normal pressure hydrocephalus, vascular, drug induced, or infectious parkinsonism. Several authors in different countries have rep...

journal_title：Chemical senses

authors： Millar Vernetti P,Rossi M,Cerquetti D,Perez Lloret S,Merello M

更新日期：2016-01-01 00:00:00

abstract：:In this study, 40 Japanese, 44 German and 39 Mexican women were presented with 18 everyday odorants. They were asked to rate them for intensity on a six-point scale from not detectable to very strong, for pleasantness on an 11-point scale from -5, to neutral at 0, to +5, and for familiarity on a six-point scale from c...

journal_title：Chemical senses

authors： Distel H,Ayabe-Kanamura S,Martínez-Gómez M,Schicker I,Kobayakawa T,Saito S,Hudson R

更新日期：1999-04-01 00:00:00

abstract：:Phantosmia, the perception of an odor when there are no odorants in the environment, can be a very debilitating symptom. In the 1960s, Zilstorff reported olfactory distortions could be treated by the topical application of a cocaine solution to the olfactory epithelium. In evaluating this treatment, we observed no lon...

journal_title：Chemical senses

authors： Leopold DA,Hornung DE

更新日期：2013-11-01 00:00:00

abstract：:Emotion and odor scales (EOS) measuring odor-related affective feelings were recently developed for three different countries (Switzerland, United Kingdom, and Singapore). The first aim of this study was to investigate gender and cultural differences in verbal affective response to odors, measured with EOS and the usu...

journal_title：Chemical senses

authors： Ferdenzi C,Roberts SC,Schirmer A,Delplanque S,Cekic S,Porcherot C,Cayeux I,Sander D,Grandjean D

更新日期：2013-02-01 00:00:00

abstract：:The capacity of the peripheral olfactory system to recover after injury has not been thoroughly explored. P2-IRES-tauLacZ mice were exposed to methyl bromide, which causes epithelial damage and kills 90% of the P2 neurons. With subsequent neuronal regeneration, P2 neurons recover within their usual territory to equal ...

journal_title：Chemical senses

authors： Holbrook EH,Iwema CL,Peluso CE,Schwob JE

更新日期：2014-09-01 00:00:00

abstract：:Glutathione, a natural substance, acts on calcium receptors on the tongue and is known to enhance basic taste sensations. However, the effects of glutathione on brain activity associated with taste sensation on the tongue have not been determined under standardized taste delivery conditions. In this study, we investig...

journal_title：Chemical senses

authors： Goto TK,Yeung AW,Tanabe HC,Ito Y,Jung HS,Ninomiya Y

更新日期：2016-09-01 00:00:00

abstract：:Olfaction involves a dual sensory process for perceiving odors orthonasally (through the nostrils) and retronasally (through the mouth). This investigation entailed developing a measure of sensitivity to an odor delivered in an orally sampled food (orange flavoring in a sucrose-sweetened gelatin) and examining sensiti...

journal_title：Chemical senses

authors： Duffy VB,Cain WS,Ferris AM

更新日期：1999-12-01 00:00:00