Abstract:
:The vomeronasal organ (VNO) is important for activating accessory olfactory pathways that are involved in sexually dimorphic mating behavior. The VNO of male garter snakes is critically important for detection of, and response to, female sex pheromones. In the present study, under voltage-clamp conditions, male snake VNO neurons were stimulated with female sexual attractiveness pheromone. Thirty-nine of 139 neurons exhibited inward current responses (reversal potential: -10.6 +/- 2.8 mV). The amplitude of the inward current was dose dependent, and the relationship could be fitted by the Hill equation. Under current-clamp conditions, application of pheromone produced membrane depolarizing responses and increases in firing frequency. These results suggest that the female pheromone directly affects male snake VNO neurons and results in opening of ion channels, thereby converting the pheromone signal to an electrical signal. The response to female pheromone is sexually dimorphic, that is, the pheromone does not evoke responses in VNO neurons of female snakes. An associated finding of the present study is that the female sex pheromone, which is insoluble in aqueous solutions, became soluble in the presence of Harderian gland homogenate.
journal_name
Chem Sensesjournal_title
Chemical sensesauthors
Huang GZ,Zhang JJ,Wang D,Mason RT,Halpern Mdoi
10.1093/chemse/bjj056subject
Has Abstractpub_date
2006-07-01 00:00:00pages
521-9issue
6eissn
0379-864Xissn
1464-3553pii
bjj056journal_volume
31pub_type
杂志文章相关文献
CHEMICAL SENSES文献大全abstract::In recent years there have been a number of important advances in the understanding of cellular mechanisms related to olfactory function. Hypotheses regarding the complex relationships among odorant structure, physiological activity and behavioral outcome generated by these findings, however, remain largely untested d...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/22.3.277
更新日期:1997-06-01 00:00:00
abstract::The mammalian olfactory system can discriminate between volatile molecules with subtle differences in their molecular structures. Efforts in synthetic chemistry have delivered a myriad of smelling compounds of different qualities as well as many molecules with very similar olfactive properties. One important class of ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjh050
更新日期:2004-07-01 00:00:00
abstract::Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to indu...
journal_title:Chemical senses
pub_type: 杂志文章,随机对照试验
doi:10.1093/chemse/bjv068
更新日期:2016-02-01 00:00:00
abstract::A list of 147 tetralin- and indan-like compounds was compiled from the literature for investigating the relationship between molecular structure and musk odor. Each compound in the data set was represented by 374 CODESSA and 970 TAE descriptors. A genetic algorithm (GA) for pattern recognition analysis was used to id...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjs058
更新日期:2012-10-01 00:00:00
abstract::The role of odors in the long-distance navigation of birds has elicited intense debate for more than half a century. Failure to resolve many of the issues fueling this debate is due at least in part to the absence of controls for a variety of non-specific effects that odors have on the navigational process. The presen...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjw084
更新日期:2016-11-01 00:00:00
abstract::Glomeruli, neuropilar structures composed of olfactory receptor neuron (ORN) axon terminals and central neuron dendrites, are a common feature of olfactory systems. Typically, ORN axons segregate into glomeruli based on odor specificity, making glomeruli the basic unit for initial processing of odorant information. De...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjj024
更新日期:2006-03-01 00:00:00
abstract::The antisense DNA method has been used successfully to block the expression of specific genes in vivo in neuronal systems. An increasing number of studies in the last few years have shown that antisense DNA administered directly into the brain can modify various kinds of behaviors. These findings strongly suggest that...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/23.2.249
更新日期:1998-04-01 00:00:00
abstract::The purpose of this study was to determine the degree to which the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid (Na-PMP) reduced sweet intensity ratings of 15 sweeteners in mixtures. Na-PMP has been approved for use in confectionary/frostings, soft candy and snack products in the USA at concentrations up to 15...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/24.4.439
更新日期:1999-08-01 00:00:00
abstract::Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/26.7.845
更新日期:2001-09-01 00:00:00
abstract::The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mi...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjv065
更新日期:2016-02-01 00:00:00
abstract::Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/bjx028
更新日期:2017-10-01 00:00:00
abstract::Despite long and intense research, some fundamental questions regarding representation of taste information in the brain still remain unanswered. This might in part be due to shortcomings of the established methods that limit the researcher either to thorough characterization of few elements or to analyze the response...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy017
更新日期:2018-04-23 00:00:00
abstract::The terminal nerve, which innervates the nasal epithelia of most jawed vertebrates, is believed to release neuropeptides that modulate activity of sensory receptor neurons. The terminal nerve usually contains gonadotropin-releasing hormone as well as at least one other peptide that has not been characterized, but whic...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/28.4.339
更新日期:2003-05-01 00:00:00
abstract::The septal organ of Masera (SO) is a small, isolated patch of olfactory epithelium, located in the ventral part of the nasal septum. We investigated in this systematic study the postnatal development of the SO in histological sections of rats at various ages from the day of birth (P1) to P666. The SO-area increases to...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjg047
更新日期:2003-09-01 00:00:00
abstract::The importance of stimulus timing and location on the perceptual integration of taste and odour was studied based on a sub-threshold methodology. From a panel of 16 people, 12 showed the integration effect previously reported while 4 showed no effect. The experiment was repeated using retronasal and orthonasal deliver...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bji047
更新日期:2005-09-01 00:00:00
abstract::Adaptation techniques have traditionally been employed in sensory physiology and psychology to characterize afferent pathways and to dissect the quantitative and, to a lesser degree, the qualitative aspects of perception. We continue to explore the individual differences in olfactory capabilities among subjects initia...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/19.3.197
更新日期:1994-06-01 00:00:00
abstract::Cells, identified as supporting cells by Lucifer Yellow injection, were recorded from slices of frog olfactory epithelium using patch-clamp recordings. Cell-attached single-channel recordings indicated that the intracellular potential (IP) was -68 +/- 7 mV (n = 22) with 4 mM K+ in the bath ([K+]o). IP was -67 +/- 4 mV...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/23.3.363
更新日期:1998-06-01 00:00:00
abstract::We report 2 experiments designed to investigate the effect of people's prior beliefs concerning specific color-flavor associations on their ability to discriminate the flavor of colored sugar-coated chocolate sweets. The participants in our study judged whether pairs of Smarties had the same flavor or not. In our firs...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjn008
更新日期:2008-06-01 00:00:00
abstract::Two experiments, using different ranges and numbers of stimuli, examined how linguistic labels affect the identification of flavor mixtures containing different proportions of sucrose (gustatory flavorant) and citral (olfactory flavorant). Both experiments asked subjects to identify each stimulus as having either "mos...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjs142
更新日期:2013-05-01 00:00:00
abstract::In order to study potential mixture interactions among bitter compounds, selected sodium salts were added to five compounds presented either alone or as binary bitter-compound mixtures. Each compound was tested at a concentration that elicited 'weak' perceived bitterness. The bitter compounds were mixed at these conce...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjh045
更新日期:2004-06-01 00:00:00
abstract::Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjy074
更新日期:2019-01-01 00:00:00
abstract::Olfactory lamellae of teleosts contain two morphologically different types of olfactory receptor neurons (ORNs): ciliated ORNs (cORNs) and microvillous ORNs (mORNs). However, little is known about the functional difference between these two types of ORNs in fish olfaction. We isolated cORNs and mORNs using a Ca(2+)-fr...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/26.9.1145
更新日期:2001-11-01 00:00:00
abstract::Female gypsy moths emit a pheromone, (+)-disparlure, which the males follow until they locate the emitter. The male moths' antennae are covered with innervated sensory hairs, specialized in detection of the pheromone. The neurons in these sensory hairs are bathed by a solution rich in pheromone-binding protein (PBP). ...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjq130
更新日期:2011-03-01 00:00:00
abstract::Plants release hundreds of volatiles that are important in interactions with insects or other organisms. However, knowledge is scarce as to which of the compounds are detected by the organism's olfactory receptor neurons. In the present study, single receptor neurons on the antennae of the tobacco budworm moth, Heliot...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/25.2.141
更新日期:2000-04-01 00:00:00
abstract::Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/27.7.611
更新日期:2002-09-01 00:00:00
abstract::In this issue of Chemical Senses, Baker et al. propose a provocative and intriguing explanation for a commonly observed phenomenon in moth chemocommunication. Sex pheromones in moths typically consist of mixtures of long-chain unsaturated compounds in specific ratios. These ratios are correspondingly detected by male ...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjs007
更新日期:2012-05-01 00:00:00
abstract::Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/bjp088
更新日期:2010-02-01 00:00:00
abstract::Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...
journal_title:Chemical senses
pub_type: 杂志文章
doi:10.1093/chemse/21.5.507
更新日期:1996-10-01 00:00:00
abstract::The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...
journal_title:Chemical senses
pub_type: 评论,杂志文章
doi:10.1093/chemse/bjx002
更新日期:2017-03-01 00:00:00
abstract::The state of the art in aroma analysis is reviewed with emphasis on aroma-recombination studies using synthetic blends of odorants (aroma models) which have been prepared on the basis of analytical data. The model that matches the original aroma is the starting material for omission experiments which are performed to ...
journal_title:Chemical senses
pub_type: 杂志文章,评审
doi:10.1093/chemse/26.5.533
更新日期:2001-06-01 00:00:00