Asymmetrical Processing of Olfactory Input in the Piriform Cortex Mediates "Activation" of the Avian Navigation Circuitry.

Abstract:

:The role of odors in the long-distance navigation of birds has elicited intense debate for more than half a century. Failure to resolve many of the issues fueling this debate is due at least in part to the absence of controls for a variety of non-specific effects that odors have on the navigational process. The present experiments were carried out to investigate whether the olfactory inputs are involved only in "activation" of neuronal circuitry involved in navigation or are also playing a role in providing directional information. Experienced adult pigeons were exposed to controlled olfactory stimuli during different segments of the journey (release site vs. displacement + release site). Protein levels of IEGs (immediate early genes used to mark synaptic activity) were analyzed in areas within the olfactory/navigation avian circuitry. The results indicate that 1) exposure to natural odors at the release site (and not before) elicit greater activation across brain regions than exposure to filtered air, artificial odors, and natural odors along the entire outward journey (from home to the release site, inclusive); 2) activation of the piriform cortex in terms of odor discrimination is lateralized; 3) activation of the navigation circuitry is achieved by means of lateralized activation of piriform cortex neurons. Altogether, the findings provide the first direct evidence that activation of the avian navigation circuitry is mediated by asymmetrical processing of olfactory input occurring in the right piriform cortex.

journal_name

Chem Senses

journal_title

Chemical senses

authors

Jorge PE,Marques PAM,Pinto BV,Phillips JB

doi

10.1093/chemse/bjw084

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

745-754

issue

9

eissn

0379-864X

issn

1464-3553

pii

bjw084

journal_volume

41

pub_type

杂志文章
  • Taste perception with age: generic or specific losses in threshold sensitivity to the five basic tastes?

    abstract::Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/26.7.845

    authors: Mojet J,Christ-Hazelhof E,Heidema J

    更新日期:2001-09-01 00:00:00

  • Memory for brief, widely spaced odor presentations in the rat.

    abstract::Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/20.2.183

    authors: Lovelace CT,Slotnick BM

    更新日期:1995-04-01 00:00:00

  • Simplifying the Odor Landscape.

    abstract::The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...

    journal_title:Chemical senses

    pub_type: 评论,杂志文章

    doi:10.1093/chemse/bjx002

    authors: Trimmer C,Mainland JD

    更新日期:2017-03-01 00:00:00

  • Expression patterns of odorant receptors and response properties of olfactory sensory neurons in aged mice.

    abstract::The sense of smell deteriorates in normal aging, but the underling mechanisms are still elusive. Here we investigated age-related alterations in expression patterns of odorant receptor (OR) genes and functional properties of olfactory sensory neurons (OSNs)-2 critical factors that define the odor detection threshold i...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjp056

    authors: Lee AC,Tian H,Grosmaitre X,Ma M

    更新日期:2009-10-01 00:00:00

  • The origin of slow potentials on the tongue surface induced by frog glossopharyngeal efferent fiber stimulation.

    abstract::When the glossopharyngeal (GP) nerve of the frog was stimulated electrically, electropositive slow potentials were recorded from the tongue surface and depolarizing slow potentials from taste cells in the fungiform papillae. The amplitude of the slow potentials was stimulus strength- and the frequency-dependent. Gener...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/25.5.583

    authors: Sato T,Toda K,Miyamoto T,Okada Y,Fujiyama R

    更新日期:2000-10-01 00:00:00

  • Temperature Affects Human Sweet Taste via At Least Two Mechanisms.

    abstract::The reported effects of temperature on sweet taste in humans have generally been small and inconsistent. Here, we describe 3 experiments that follow up a recent finding that cooling from 37 to 21 °C does not reduce the initial sweetness of sucrose but increases sweet taste adaptation. In experiment 1, subjects rated t...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjv021

    authors: Green BG,Nachtigal D

    更新日期:2015-07-01 00:00:00

  • Potential semiochemical molecules from birds: a practical and comprehensive compilation of the last 20 years studies.

    abstract::During the past 2 decades, considerable progress has been made in the study of bird semiochemistry, and our goal was to review and evaluate this literature with particular emphasis on the volatile organic constituents. Indeed, since the importance of social chemosignaling in birds is becoming more and more apparent, t...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjr067

    authors: Campagna S,Mardon J,Celerier A,Bonadonna F

    更新日期:2012-01-01 00:00:00

  • Olfactory discrimination of amino acids in brown bullhead catfish.

    abstract::Olfactory discrimination of amino acids was investigated in brown bullhead catfish (Ameiurus nebulosus). Based on the magnitude of the observed food search activity of catfish conditioned to single amino acids, the tested compounds were classified as being detected by the catfish as equal to, similar to, or different ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/25.1.21

    authors: Valentincic T,Metelko J,Ota D,Pirc V,Blejec A

    更新日期:2000-02-01 00:00:00

  • Study of the olfactory epithelium in the developing sturgeon. Characterization of the crypt cells.

    abstract::In acipenserids, crypt cells (CCs) have only been observed in juvenile specimens, and it has not been clarified whether they differentiate along with olfactory receptor neurons (ORNs) during the lecithotrophic stage or during later development stages. Furthermore, no detailed optical microscopy (OM) or electron micros...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjp091

    authors: Camacho S,Ostos-Garrido MV,Domezain A,Carmona R

    更新日期:2010-02-01 00:00:00

  • Female snake sex pheromone induces membrane responses in vomeronasal sensory neurons of male snakes.

    abstract::The vomeronasal organ (VNO) is important for activating accessory olfactory pathways that are involved in sexually dimorphic mating behavior. The VNO of male garter snakes is critically important for detection of, and response to, female sex pheromones. In the present study, under voltage-clamp conditions, male snake ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjj056

    authors: Huang GZ,Zhang JJ,Wang D,Mason RT,Halpern M

    更新日期:2006-07-01 00:00:00

  • Alarm reaction in the crucian carp is mediated by the medial bundle of the medial olfactory tract.

    abstract::Experiments were performed to determine which bundles of the olfactory tracts were essential for mediating alarm reaction in crucian carp (Carassius carassius L.). The fish were maintained in physiological saline after surgery to preserve the remaining tracts and postoperative inspections revealed the functionality of...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/25.1.103

    authors: Hamdani EH,Stabell OB,Alexander G,Døving KB

    更新日期:2000-02-01 00:00:00

  • Tastant-Evoked Arc Expression in the Nucleus of the Solitary Tract and Nodose/Petrosal Ganglion of the Mouse Is Specific for Bitter Compounds.

    abstract::Despite long and intense research, some fundamental questions regarding representation of taste information in the brain still remain unanswered. This might in part be due to shortcomings of the established methods that limit the researcher either to thorough characterization of few elements or to analyze the response...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjy017

    authors: Töle J,Stolzenburg A,Tyree SM,Stähler F,Meyerhof W

    更新日期:2018-04-23 00:00:00

  • Mosaic analysis of the embryonic origin of taste buds.

    abstract::The embryonic origins of taste receptor cells have not been established experimentally. Although related receptor cells (e.g. hair cells of the inner ear, lateral line receptors) are known to arise from neurogenic ectoderm (e.g. neural crest or placodes), taste buds are described as arising from local epithelial cells...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/19.6.725

    authors: Stone LM,Finger TE

    更新日期:1994-12-01 00:00:00

  • Anosmia-A Clinical Review.

    abstract::Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disord...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjx025

    authors: Boesveldt S,Postma EM,Boak D,Welge-Luessen A,Schöpf V,Mainland JD,Martens J,Ngai J,Duffy VB

    更新日期:2017-09-01 00:00:00

  • Human odor detectability: new methodology used to determine threshold and variation.

    abstract::Current ambiguity concerning the related issues of optimal means for measurement of odor sensitivity and the functional properties of the olfactory system hinders progress in basic and applied research on the human sense of smell. To address these needs, we selected n-amyl acetate (nAA) as a test odorant and developed...

    journal_title:Chemical senses

    pub_type: 临床试验,杂志文章

    doi:10.1093/chemse/bjg075

    authors: Walker JC,Hall SB,Walker DB,Kendal-Reed MS,Hood AF,Niu XF

    更新日期:2003-11-01 00:00:00

  • Alarm pheromone that aggravates stress-induced hyperthermia is soluble in water.

    abstract::We previously reported that stressed male Wistar rats released alarm pheromone from the perianal region, which aggravated stress-induced hyperthermia and increased Fos expression in the mitral/tufted cell layer of the accessory olfactory bulb in recipient rats. In this study, we attempted to obtain this pheromone in w...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bji044

    authors: Kiyokawa Y,Kikusui T,Takeuchi Y,Mori Y

    更新日期:2005-07-01 00:00:00

  • Olfactory Coding in Antennal Neurons of the Malaria Mosquito, Anopheles gambiae.

    abstract::Olfactory receptor neurons (ORNs) in the antenna of insects serve to encode odors in action potential activity conducted to the olfactory lobe of the deuterocerebrum. We performed an analysis of the electrophysiological responses of olfactory neurons in the antennae of the female malaria mosquito Anopheles gambiae s.s...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjl027

    authors: Qiu YT,van Loon JJ,Takken W,Meijerink J,Smid HM

    更新日期:2006-11-01 00:00:00

  • Subunit contributions to insect olfactory receptor function: channel block and odorant recognition.

    abstract::Insect olfactory receptors are heteromeric ligand-gated ion channels composed of at least one common subunit (Orco) and at least one subunit that confers odorant specificity. Little is known about how individual subunits contribute to the structure and function of the olfactory receptor complex. We expressed insect ol...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjr053

    authors: Nichols AS,Chen S,Luetje CW

    更新日期:2011-11-01 00:00:00

  • Olfactory cocainization is not an effective long-term treatment for phantosmia.

    abstract::Phantosmia, the perception of an odor when there are no odorants in the environment, can be a very debilitating symptom. In the 1960s, Zilstorff reported olfactory distortions could be treated by the topical application of a cocaine solution to the olfactory epithelium. In evaluating this treatment, we observed no lon...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjt047

    authors: Leopold DA,Hornung DE

    更新日期:2013-11-01 00:00:00

  • Odor Emotional Quality Predicts Odor Identification.

    abstract::It is commonly agreed upon a strong link between emotion and olfaction. Odor-evoked memories are experienced as more emotional compared with verbal, visual, and tactile stimuli. Moreover, the emotional quality of odor cues increases memory performance, but contrary to this, odors are poor retrieval cues for verbal lab...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjv037

    authors: Bestgen AK,Schulze P,Kuchinke L

    更新日期:2015-09-01 00:00:00

  • Anterior tongue stimulation with amiloride suppresses NaCl saltiness, but not citric acid sourness in humans.

    abstract::Suppression of the saltiness of NaCl solutions by amiloride, a sodium channel blocker, has previously been reported a number of times in humans. This suppression was seen with techniques that involved stimulation of small areas of the tongue. It was not certain, however, whether amiloride would suppress saltiness with...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.2.113

    authors: Tennissen AM,McCutcheon NB

    更新日期:1996-04-01 00:00:00

  • Distracted Sniffing of Food Odors Leads to Diminished Behavioral and Neural Responses.

    abstract::Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...

    journal_title:Chemical senses

    pub_type: 评论,杂志文章

    doi:10.1093/chemse/bjx060

    authors: Veldhuizen MG

    更新日期:2017-10-31 00:00:00

  • The Perceptual Characteristics of Sodium Chloride to Sodium-Depleted Rats.

    abstract::Three experiments assessed potential changes in the rat's perception of sodium chloride (NaCl) during a state of sodium appetite. In Experiment 1, sodium-sufficient rats licking a range of NaCl concentrations (0.028-0.89M) in 15s trials showed an inverted U-shaped concentration response function peaking at 0.281M. Dep...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjw100

    authors: St John SJ

    更新日期:2017-02-01 00:00:00

  • Interspecific variation of olfactory preferences in flies, mice, and humans.

    abstract::Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjy074

    authors: Manoel D,Makhlouf M,Scialdone A,Saraiva LR

    更新日期:2019-01-01 00:00:00

  • Preference for sucralose predicts behavioral responses to sweet and bittersweet tastants.

    abstract::Rats can be classified as either sucralose avoiders (SA) or sucralose preferrers (SP) based on their behavioral responses in 2-bottle preference, 1-bottle intake, and brief-access licking tests. The present study demonstrates that this robust phenotypic variation in the preference for sucralose predicts acceptance of ...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjr126

    authors: Loney GC,Torregrossa AM,Carballo C,Eckel LA

    更新日期:2012-06-01 00:00:00

  • Evaluation of copper speciation and water quality factors that affect aqueous copper tasting response.

    abstract::This study determined taste thresholds for copper as its speciation was varied among free cupric ion, complexed cupric ion, and precipitated cupric particles. The impact of copper chemistry on taste is important as copper is added to many beverages and can be present in drinking water as a natural mineral or due to co...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/bjl010

    authors: Cuppett JD,Duncan SE,Dietrich AM

    更新日期:2006-09-01 00:00:00

  • Calcium signaling in taste cells: regulation required.

    abstract::Peripheral taste receptor cells depend on distinct calcium signals to generate appropriate cellular responses that relay taste information to the central nervous system. Some taste cells have conventional chemical synapses and rely on calcium influx through voltage-gated calcium channels. Other taste cells lack these ...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/bjq082

    authors: Medler KF

    更新日期:2010-11-01 00:00:00

  • The plant sesquiterpene germacrene D specifically activates a major type of antennal receptor neuron of the tobacco budworm moth Heliothis virescens.

    abstract::Plants release hundreds of volatiles that are important in interactions with insects or other organisms. However, knowledge is scarce as to which of the compounds are detected by the organism's olfactory receptor neurons. In the present study, single receptor neurons on the antennae of the tobacco budworm moth, Heliot...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/25.2.141

    authors: Røstelien T,Borg-Karlson AK,Fäldt J,Jacobsson U,Mustaparta H

    更新日期:2000-04-01 00:00:00

  • Chemoreceptive control of feeding processes in hydra.

    abstract::Cnidarians are the simplest metazoans to exhibit satiety after feeding. When hydra are fed to repletion, they close their mouths and cease to capture prey. As feeding stops, contractions of the tentacles and body column increase. Our earlier experiments showed that a gel chromatographic fraction of prey substances inh...

    journal_title:Chemical senses

    pub_type: 杂志文章

    doi:10.1093/chemse/21.3.313

    authors: Grosvenor W,Rhoads DE,Kass-Simon G

    更新日期:1996-06-01 00:00:00

  • Dopamine regulation of transcription factor-target interactions in rat striatum.

    abstract::Transcriptional regulation is an important mechanism by which neurons adapt to environmental stimuli. The indirect dopamine agonists, amphetamine and cocaine have been shown to induce expression of immediate early genes, such as c-fos, and neuropeptide genes, such as prodynorphin in the rat striatum. Here we show that...

    journal_title:Chemical senses

    pub_type: 杂志文章,评审

    doi:10.1093/chemse/20.2.257

    authors: Hyman SE,Cole RL,Konradi C,Kosofsky BE

    更新日期:1995-04-01 00:00:00