Selective inhibition of sweetness by the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid.

abstract：:Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....

journal_title：Chemical senses

authors： Mojet J,Christ-Hazelhof E,Heidema J

更新日期：2001-09-01 00:00:00

abstract：:Taste sensitivity is assessed with various techniques, including absolute detection and quality recognition. For any stimulus, one might expect individual differences in sensitivity to be reflected in all measures, but they are often surprisingly independent. Here, we focus on sensitivity to sour and salty taste, in p...

journal_title：Chemical senses

authors： Wise PM,Breslin PA

更新日期：2013-05-01 00:00:00

abstract：:Odor and lateralization (irritation) thresholds (LTs) for ammonia vapor were measured using static and dynamic olfactometry. The purpose of the study was to explore the test-retest reliability and comparability of dynamic olfactometry methodology, generally used to determine odor thresholds following European Committe...

journal_title：Chemical senses

authors： Smeets MA,Bulsing PJ,van Rooden S,Steinmann R,de Ru JA,Ogink NW,van Thriel C,Dalton PH

更新日期：2007-01-01 00:00:00

abstract：:In recent years there have been a number of important advances in the understanding of cellular mechanisms related to olfactory function. Hypotheses regarding the complex relationships among odorant structure, physiological activity and behavioral outcome generated by these findings, however, remain largely untested d...

journal_title：Chemical senses

authors： Dorries KM,White J,Kauer JS

更新日期：1997-06-01 00:00:00

abstract：:In order to explore the cross-modal cognitive associations between smell and taste, a chemosensory analogue of the Stroop task (Stroop 1935) was developed. Fourteen participants were presented with an odorant and a tastant and asked to identify the tastant as "sweet" or "sour" by pressing 1 of 2 buttons as quickly as ...

journal_title：Chemical senses

authors： White TL,Prescott J

更新日期：2007-05-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:The central projections of olfactory receptor cells associated with two distinct types of antennal sensilla in the sphinx moth Manduca sexta were revealed by anterograde staining. In both sexes, receptor axons that arise from sexually isomorphic, type-II trichoid sensilla (and possibly some basiconic sensilla) project...

journal_title：Chemical senses

authors： Christensen TA,Harrow ID,Cuzzocrea C,Randolph PW,Hildebrand JG

更新日期：1995-06-01 00:00:00

abstract：:The perceived bitterness intensity for bitter solutions of propylthiouracil (PROP), sucrose octa-acetate (SOA), quinine HCl and caffeine were examined in a genetically informative sample of 392 females and 313 males (mean age of 17.8 +/- 3.1 years), including 62 monozygotic and 131 dizygotic twin pairs and 237 sib pai...

journal_title：Chemical senses

authors： Hansen JL,Reed DR,Wright MJ,Martin NG,Breslin PA

更新日期：2006-06-01 00:00:00

abstract：:The experiments had 2 main goals: 1) to add to the sparse literature on how retronasal aromas interact with bitter tastes, and 2) to determine whether modulation of taste intensity by aroma depends on temporal contiguity, as one might expect if flavor interactions depend on cross-modal binding (similar to object perce...

journal_title：Chemical senses

authors： Isogai T,Wise PM

更新日期：2016-09-01 00:00:00

abstract：:There is no natural physical continuum for odor quality along which an odor quality discrimination (OQD) threshold can be measured. In an attempt to overcome this problem, the substitution-reciprocity (SURE) method defines a framework for the measurement of an OQD threshold. More specifically, it (i) defines a thresho...

journal_title：Chemical senses

authors： Olsson MJ,Cain WS

更新日期：2000-10-01 00:00:00

abstract：:Cells, identified as supporting cells by Lucifer Yellow injection, were recorded from slices of frog olfactory epithelium using patch-clamp recordings. Cell-attached single-channel recordings indicated that the intracellular potential (IP) was -68 +/- 7 mV (n = 22) with 4 mM K+ in the bath ([K+]o). IP was -67 +/- 4 mV...

journal_title：Chemical senses

authors： Trotier D

更新日期：1998-06-01 00:00:00

abstract：:The G protein subunit alpha-gustducin is expressed in a subset of light (Type II) but not in dark (Type I) cells in rat vallate taste buds. The thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) is incorporated into DNA during the S-phase of the cell cycle and can be used to determine the time of origin of a cell. In t...

journal_title：Chemical senses

authors： Cho YK,Farbman AI,Smith DV

更新日期：1998-12-01 00:00:00

abstract：:Since starch is a significant part of human diet, its oral detection would be highly beneficial. This study was designed to determine whether starch or its degradation products can be tasted and what factors influence its perception. Subjects were asked 1) to taste 8% raw and cooked starch samples for 5, 15, and 35 s ...

journal_title：Chemical senses

authors： Lapis TJ,Penner MH,Balto AS,Lim J

更新日期：2017-10-01 00:00:00

abstract：:Glucose is a universal phagostimulant in many animal species, including the cockroach Blattella germanica. However, some natural populations of B. germanica have been found that are behaviorally deterred from eating glucose. In dose-response studies, glucose was a powerful phagostimulant for wild-type cockroaches, but...

journal_title：Chemical senses

authors： Wada-Katsumata A,Silverman J,Schal C

更新日期：2011-09-01 00:00:00

abstract：:Evidence suggests that women outperform men in core aspects of odor perception, and sex hormones may play a significant role in moderating this effect. The gender-affirming treatment (GAT) of transgender persons constitutes a powerful natural experiment to study the psychological and behavioral effects of high dosages...

journal_title：Chemical senses

authors： Kranz GS,Kaufmann U,Lanzenberger R

更新日期：2020-01-01 00:00:00

abstract：:The perception of sweetness and flavour were studied in viscous solutions containing 50 g/l sucrose, 100 p.p.m. iso-amyl acetate and varying concentrations of three hydrocolloid thickeners (guar gum, lambda-carrageenan and hydroxypropylmethyl cellulose). Zero-shear viscosity of the samples ranged from 1 to 5000 mPas. ...

journal_title：Chemical senses

authors： Cook DJ,Hollowood TA,Linforth RS,Taylor AJ

更新日期：2003-01-01 00:00:00

abstract：:Response accuracy and odor-sampling times were used to compare the ability of mice to detect (+)-carvone and (+)-terpinen-4-ol and to discriminate between enantiomers of carvone and of terpinen-4-ol. Except for increased odor sampling when mice were first exposed to the (+)-carvone odor, there was no difference in odo...

journal_title：Chemical senses

authors： Slotnick B

更新日期：2007-09-01 00:00:00

abstract：:The (E)-3-methyl-2-hexenoic acid (E3M2H), an axillary odor-related compound, is known to occur in Caucasians. The aims of this study were to clarify whether E3M2H contributes to axillary odor in Asians and to quantify and compare individual levels of E3M2H. Quantitative determination of E3M2H was performed by means of...

journal_title：Chemical senses

authors： Akutsu T,Sekiguchi K,Ohmori T,Sakurada K

更新日期：2006-07-01 00:00:00

abstract：:Hyperosmia is suspected in pregnancy; however, no empirical study using validated measures of olfactory function has clearly confirmed the anecdotal reports of this phenomenon. The goal of the current study is to compare the olfactory sensitivity of pregnant women to that of nonpregnant women and men. All participants...

journal_title：Chemical senses

authors： Cameron EL

更新日期：2014-02-01 00:00:00

abstract：:Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with...

journal_title：Chemical senses

authors： Schmidt R,Cain WS

更新日期：2010-02-01 00:00:00

abstract：:The prevalence of obesity and obesity-related disorders such as type 2 diabetes (T2D) and metabolic syndrome has increased significantly in the past decades, reaching epidemic levels and therefore becoming a major health issue worldwide. Chronic overeating of highly palatable foods is one of the main responsible aspec...

journal_title：Chemical senses

authors： Tarragon E,Moreno JJ

更新日期：2017-12-25 00:00:00

abstract：:In working and practical contexts, dogs rely upon their ability to discriminate a target odor from distracting odors and other sensory stimuli. Using awake functional magnetic resonance imaging (fMRI) in 18 dogs, we examined the neural mechanisms underlying odor discrimination between 2 odors and a mixture of the odor...

journal_title：Chemical senses

authors： Prichard A,Chhibber R,King J,Athanassiades K,Spivak M,Berns GS

更新日期：2020-12-05 00:00:00

abstract：:Activity-dependent processes are important to olfactory sensory neurons (OSNs) in several ways, such as cell survival and the specificity of axonal convergence. The identification of activity-dependent mRNAs has contributed to our understanding of OSN axon convergence, but has revealed surprisingly little about other ...

journal_title：Chemical senses

authors： Wang Q,Titlow WB,McClintock DA,Stromberg AJ,McClintock TS

更新日期：2017-10-01 00:00:00

abstract：:Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight ...

journal_title：Chemical senses

authors： Proserpio C,Laureati M,Bertoli S,Battezzati A,Pagliarini E

更新日期：2016-02-01 00:00:00

abstract：:Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...

journal_title：Chemical senses

authors： Georgiopoulos C,Witt ST,Haller S,Dizdar N,Zachrisson H,Engström M,Larsson EM

更新日期：2018-07-05 00:00:00

abstract：:The aim of this study was to investigate the relationship of fungiform papillae density with taste detection thresholds for sucrose of young male adults. One hundred and eighty two subjects aged 18-23 years (mean age: 21.9 +/- 1.2 years) were included. The densities of fungiform papillae were recorded with the aid of ...

journal_title：Chemical senses

authors： Zhang GH,Zhang HY,Wang XF,Zhan YH,Deng SP,Qin YM

更新日期：2009-01-01 00:00:00

abstract：:Our study was designed to examine how components of complex mixtures can inhibit the binding of other components to receptor sites in the olfactory system of the spiny lobster Panulirus argus. Biochemical binding assays were used to study how two- to six-component mixtures inhibit binding of the radiolabeled odorants ...

journal_title：Chemical senses

authors： Gentilcore LR,Derby CD

更新日期：1998-06-01 00:00:00

abstract：:The present study demonstrated that 100 microM amiloride serves as an ineffective conditioned taste stimulus in a taste aversion paradigm. Even if amiloride has a detectable taste, it's unlikely that its behavioral effects in salt mixture experiments are due to its inherent taste quality. ...

journal_title：Chemical senses

authors： Markison S,Spector AC

更新日期：1995-10-01 00:00:00

abstract：:Biological detectors such as the human nose or an insect antenna represent extremely attractive detectors for gas chromatography (GC) since they are specifically tuned to perceive biologically relevant compounds. However, these detectors are nonlinear, noisy and often perform poorly under standard GC conditions since ...

journal_title：Chemical senses

authors： Gouinguené S,de Cruz I,van der Pers J,Wadhams L,Marion-Poll F

更新日期：1998-12-01 00:00:00

abstract：:Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...

journal_title：Chemical senses

authors： Harder DB,Gannon KS,Whitney G

更新日期：1996-10-01 00:00:00