Amiloride is an ineffective conditioned stimulus in taste aversion learning.

abstract：:The effects of the membrane-permeable dibutyryl guanosine 3', 5'-cyclic monophosphate (db-cGMP) on the bombykol-elicited receptor current and nerve impulse activity were studied using the open sensillum recording technique. db-cGMP was applied to the outer dendritic membrane of the olfactory receptor neuron of the mot...

journal_title：Chemical senses

authors： Redkozubov A

更新日期：2000-08-01 00:00:00

abstract：:To examine whether age influences taste solution preferences, we measured taste preferences of C57BL/6J and 129X1/SvJ mice given a series of 48-h 2-bottle tests with a choice between water and one of the following taste solutions: 2 mM saccharin, 5 mM citric acid, 30 microM quinine hydrochloride, 75 mM sodium chloride...

journal_title：Chemical senses

authors： Tordoff MG

更新日期：2007-09-01 00:00:00

abstract：:In this review we report data from freely breathing animals in an attempt to show how respiratory dynamics can influence bulbar and cortical activity. Relying on in vivo data as well as in vitro observations, we try to emphasize the multiple mechanisms that underlie this modulation, its multiple origins, and its possi...

journal_title：Chemical senses

authors： Buonviso N,Amat C,Litaudon P

更新日期：2006-02-01 00:00:00

abstract：:Strong electrical stimulation (ES) of the frog glossopharyngeal (GP) efferent nerve induced slow depolarizing potentials (DPs) in taste cells under hypoxia. This study aimed to elucidate whether the slow DPs were postsynaptically induced in taste cells. After a block of parasympathetic nerve (PSN) ganglia by tubocurar...

journal_title：Chemical senses

authors： Sato T,Nishishita K,Okada Y,Toda K

更新日期：2007-05-01 00:00:00

abstract：:Sight is undoubtedly not only important for food identification and selection but also for the modulation of gustatory sensitivity. We can, therefore, assume that taste sensitivity and eating habits are affected by visual deprivation from birth. We measured taste detection and identification thresholds of the 5 basic ...

journal_title：Chemical senses

authors： Gagnon L,Kupers R,Ptito M

更新日期：2013-07-01 00:00:00

abstract：:Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...

journal_title：Chemical senses

authors： Schwartz C,Chabanet C,Szleper E,Feyen V,Issanchou S,Nicklaus S

更新日期：2017-09-01 00:00:00

abstract：:Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with...

journal_title：Chemical senses

authors： Schmidt R,Cain WS

更新日期：2010-02-01 00:00:00

abstract：:Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests....

journal_title：Chemical senses

authors： Mojet J,Christ-Hazelhof E,Heidema J

更新日期：2001-09-01 00:00:00

abstract：:We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than wild-type brazzein. ...

journal_title：Chemical senses

authors： Walters DE,Cragin T,Jin Z,Rumbley JN,Hellekant G

更新日期：2009-10-01 00:00:00

abstract：:An odor emitted by an object signals the presence of that object and may draw attention to it. Can odors that are not actually emitted by an object also function as a signal? We investigated whether the degree of thematic congruency between an ambient odor and a magazine affected magazine sales in a retail store. We s...

journal_title：Chemical senses

authors： Schifferstein HN,Blok ST

更新日期：2002-07-01 00:00:00

abstract：:The vast number of detectable odors makes matching olfactory receptors (ORs) to their ligands a daunting task. Krautwurst and colleagues have hypothesized that this process can be simplified by focusing on those odorants that are perceptually relevant food odors. In this issue of Chemical Senses, they use this framewo...

journal_title：Chemical senses

authors： Trimmer C,Mainland JD

更新日期：2017-03-01 00:00:00

abstract：:Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...

journal_title：Chemical senses

authors： Leopold D

更新日期：2002-09-01 00:00:00

abstract：:Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC...

journal_title：Chemical senses

authors： Wooding SP

更新日期：2018-08-24 00:00:00

abstract：:Past research has shown that odor perception can be affected by how we label odors. The aim of this study was to expand on previous work by investigating the impact of labels on edibility, pleasantness, and intensity ratings as well as on reaction times when detecting labeled odors. We tested 50 subjects. Five odorant...

journal_title：Chemical senses

authors： Manescu S,Frasnelli J,Lepore F,Djordjevic J

更新日期：2014-02-01 00:00:00

abstract：:Rats can be classified as either sucralose avoiders (SA) or sucralose preferrers (SP) based on their behavioral responses in 2-bottle preference, 1-bottle intake, and brief-access licking tests. The present study demonstrates that this robust phenotypic variation in the preference for sucralose predicts acceptance of ...

journal_title：Chemical senses

authors： Loney GC,Torregrossa AM,Carballo C,Eckel LA

更新日期：2012-06-01 00:00:00

abstract：:Insect olfactory receptors are heteromeric ligand-gated ion channels composed of at least one common subunit (Orco) and at least one subunit that confers odorant specificity. Little is known about how individual subunits contribute to the structure and function of the olfactory receptor complex. We expressed insect ol...

journal_title：Chemical senses

authors： Nichols AS,Chen S,Luetje CW

更新日期：2011-11-01 00:00:00

abstract：:Evidence suggests that women outperform men in core aspects of odor perception, and sex hormones may play a significant role in moderating this effect. The gender-affirming treatment (GAT) of transgender persons constitutes a powerful natural experiment to study the psychological and behavioral effects of high dosages...

journal_title：Chemical senses

authors： Kranz GS,Kaufmann U,Lanzenberger R

更新日期：2020-01-01 00:00:00

abstract：:The Grueneberg ganglion (GG) in the vestibule of the anterior nasal cavity is considered as an olfactory subcompartment based on expression of the olfactory marker protein (OMP) and axonal projection to the olfactory bulb. Searching for olfactory receptors present in the GG, it has been observed recently that V2r83, a...

journal_title：Chemical senses

authors： Fleischer J,Schwarzenbacher K,Breer H

更新日期：2007-07-01 00:00:00

abstract：:When people misidentify everyday odors, as they often do, their errors may conceivably lie in faulty perceptions or in faulty access to the names. Discussions of the matter usually focus on the latter, as if people had no problems with perceptual accuracy. (The problem of faulty access may get attention because its hi...

journal_title：Chemical senses

authors： Cain WS,Potts BC

更新日期：1996-02-01 00:00:00

abstract：:Peripheral taste receptor cells depend on distinct calcium signals to generate appropriate cellular responses that relay taste information to the central nervous system. Some taste cells have conventional chemical synapses and rely on calcium influx through voltage-gated calcium channels. Other taste cells lack these ...

journal_title：Chemical senses

authors： Medler KF

更新日期：2010-11-01 00:00:00

abstract：:To analyze the mechanisms of perception and processing of pheromonal signals in vitro, we previously developed a new culture system for vomeronasal receptor neurons (VRNs), referred to as the vomeronasal pocket (VN pocket). However, very few VRNs were found to express the olfactory marker protein (OMP) and to have pro...

journal_title：Chemical senses

authors： Moriya-Ito K,Osada T,Ishimatsu Y,Muramoto K,Kobayashi T,Ichikawa M

更新日期：2005-02-01 00:00:00

abstract：:The (E)-3-methyl-2-hexenoic acid (E3M2H), an axillary odor-related compound, is known to occur in Caucasians. The aims of this study were to clarify whether E3M2H contributes to axillary odor in Asians and to quantify and compare individual levels of E3M2H. Quantitative determination of E3M2H was performed by means of...

journal_title：Chemical senses

authors： Akutsu T,Sekiguchi K,Ohmori T,Sakurada K

更新日期：2006-07-01 00:00:00

abstract：:The objective of this study was to develop a semantically labeled hedonic scale (LHS) that would yield ratio-level data on the magnitude of liking/disliking of sensation equivalent to that produced by magnitude estimation (ME). The LHS was constructed by having 49 subjects who were trained in ME rate the semantic magn...

journal_title：Chemical senses

authors： Lim J,Wood A,Green BG

更新日期：2009-11-01 00:00:00

abstract：:The aim of this study was to investigate the relationship of fungiform papillae density with taste detection thresholds for sucrose of young male adults. One hundred and eighty two subjects aged 18-23 years (mean age: 21.9 +/- 1.2 years) were included. The densities of fungiform papillae were recorded with the aid of ...

journal_title：Chemical senses

authors： Zhang GH,Zhang HY,Wang XF,Zhan YH,Deng SP,Qin YM

更新日期：2009-01-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:A list of 147 tetralin- and indan-like compounds was compiled from the literature for investigating the relationship between molecular structure and musk odor. Each compound in the data set was represented by 374 CODESSA and 970 TAE descriptors. A genetic algorithm (GA) for pattern recognition analysis was used to id...

journal_title：Chemical senses

authors： Lavine BK,White C,Mirjankar N,Sundling CM,Breneman CM

更新日期：2012-10-01 00:00:00

abstract：:Individual recognition has been studied across a number of taxa and modalities; however, few attempts have been made to combine chemical and biological approaches and arrive at a more complete understanding of the use of secretions as signals. We combined behavioral habituation experiments with gas chromatography-mass...

journal_title：Chemical senses

authors： Liu D,Huang KJ,Zhang JX

更新日期：2011-11-01 00:00:00

abstract：:Studies over the last 8 years have identified 3 potential channels that appear to release ATP from Type II cells in response to taste stimuli. These studies have taken different methodological approaches but have all provided data supporting their candidate channel as the ATP release channel. These potential channels ...

journal_title：Chemical senses

authors： Medler KF

更新日期：2015-09-01 00:00:00

abstract：:Odor and lateralization (irritation) thresholds (LTs) for ammonia vapor were measured using static and dynamic olfactometry. The purpose of the study was to explore the test-retest reliability and comparability of dynamic olfactometry methodology, generally used to determine odor thresholds following European Committe...

journal_title：Chemical senses

authors： Smeets MA,Bulsing PJ,van Rooden S,Steinmann R,de Ru JA,Ogink NW,van Thriel C,Dalton PH

更新日期：2007-01-01 00:00:00

abstract：:The perception of sweetness and flavour were studied in viscous solutions containing 50 g/l sucrose, 100 p.p.m. iso-amyl acetate and varying concentrations of three hydrocolloid thickeners (guar gum, lambda-carrageenan and hydroxypropylmethyl cellulose). Zero-shear viscosity of the samples ranged from 1 to 5000 mPas. ...

journal_title：Chemical senses

authors： Cook DJ,Hollowood TA,Linforth RS,Taylor AJ

更新日期：2003-01-01 00:00:00