Ontogeny of the solitary chemosensory cells in the zebrafish, Danio rerio.

abstract：:Social behaviors of most mammals are affected by chemical signals, pheromones, exchanged between conspecifics. Previous experiments have shown that behavioral responses to the same pheromone differ depending on the sex and endocrine status of the respondent. Although the exact mechanism of this dimorphism is not known...

journal_title：Chemical senses

authors： Thompson RN,Robertson BK,Napier A,Wekesa KS

更新日期：2004-11-01 00:00:00

abstract：:The aim of this investigation was to compare olfactory functions of patients suffering from Parkinson's disease (PD) and Alzheimer's disease (AD). Olfactory threshold, odor identification ability and odor memory performance were assessed in 21 non-demented PD patients and in 22 AD patients. Both patient groups were im...

journal_title：Chemical senses

authors： Lehrner JP,Brücke T,Dal-Bianco P,Gatterer G,Kryspin-Exner I

更新日期：1997-02-01 00:00:00

abstract：:We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than wild-type brazzein. ...

journal_title：Chemical senses

authors： Walters DE,Cragin T,Jin Z,Rumbley JN,Hellekant G

更新日期：2009-10-01 00:00:00

abstract：:The G protein subunit alpha-gustducin is expressed in a subset of light (Type II) but not in dark (Type I) cells in rat vallate taste buds. The thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) is incorporated into DNA during the S-phase of the cell cycle and can be used to determine the time of origin of a cell. In t...

journal_title：Chemical senses

authors： Cho YK,Farbman AI,Smith DV

更新日期：1998-12-01 00:00:00

abstract：:The initial steps in taste and olfaction result from the activation by chemical stimuli of taste receptor cells (TRCs) and olfactory receptor neurons (ORNs). In parallel with these two pathways is the chemosensitive trigeminal pathway whose neurons terminate in the oral and nasal cavities and which are activated by ma...

journal_title：Chemical senses

authors： Liu L,Simon SA

更新日期：1998-04-01 00:00:00

abstract：:Taste sensitivity plays a major role in controlling feeding behavior, and alterations in feeding habit induced by changes in taste sensitivity can drive speciation. We investigated variability in taste preferences in wild-derived inbred lines from the Drosophila melanogaster Genetic Reference Panel. Preferences for di...

journal_title：Chemical senses

authors： Uchizono S,Tanimura T

更新日期：2017-05-01 00:00:00

abstract：:Electrical stimulation of the frog glossopharyngeal (GP) nerve evoked slow hyperpolarizing potentials (HPs) in taste cells. This study aimed to clarify whether slow HPs were postsynaptically induced in taste cells. The slow HPs were recorded intracellularly with a microelectrode. When Ca2+ concentration in the blood p...

journal_title：Chemical senses

authors： Sato T,Okada Y,Toda K

更新日期：2004-10-01 00:00:00

abstract：:To examine the functional subdivision of the teleost olfactory bulb, extracellular recordings were made from the posterior part of the medial region of the olfactory bulb in the crucian carp, Carassius carassius. Bulbar units classified as type I or type II were frequently and simultaneously encountered at a recording...

journal_title：Chemical senses

authors： Hamdani el H,Døving KB

更新日期：2003-03-01 00:00:00

abstract：:In working and practical contexts, dogs rely upon their ability to discriminate a target odor from distracting odors and other sensory stimuli. Using awake functional magnetic resonance imaging (fMRI) in 18 dogs, we examined the neural mechanisms underlying odor discrimination between 2 odors and a mixture of the odor...

journal_title：Chemical senses

authors： Prichard A,Chhibber R,King J,Athanassiades K,Spivak M,Berns GS

更新日期：2020-12-05 00:00:00

abstract：:Extracellular neuronal responses were recorded from the posterior insular cortex following electrical and chemical stimulation of the thalamic reticular nucleus (Rt) regions. In the present study, most neurons (29/32) were first characterized for their responses to electrical stimulation of the superior laryngeal (SL)...

journal_title：Chemical senses

authors： Hanamori T

更新日期：2003-10-01 00:00:00

abstract：:Studies over the last 8 years have identified 3 potential channels that appear to release ATP from Type II cells in response to taste stimuli. These studies have taken different methodological approaches but have all provided data supporting their candidate channel as the ATP release channel. These potential channels ...

journal_title：Chemical senses

authors： Medler KF

更新日期：2015-09-01 00:00:00

abstract：:Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...

journal_title：Chemical senses

authors： Leow LP,Huckabee ML,Sharma S,Tooley TP

更新日期：2007-02-01 00:00:00

abstract：:The sense of smell deteriorates in normal aging, but the underling mechanisms are still elusive. Here we investigated age-related alterations in expression patterns of odorant receptor (OR) genes and functional properties of olfactory sensory neurons (OSNs)-2 critical factors that define the odor detection threshold i...

journal_title：Chemical senses

authors： Lee AC,Tian H,Grosmaitre X,Ma M

更新日期：2009-10-01 00:00:00

abstract：:The terminal nerve, which innervates the nasal epithelia of most jawed vertebrates, is believed to release neuropeptides that modulate activity of sensory receptor neurons. The terminal nerve usually contains gonadotropin-releasing hormone as well as at least one other peptide that has not been characterized, but whic...

journal_title：Chemical senses

authors： Park D,Zawacki SR,Eisthen HL

更新日期：2003-05-01 00:00:00

abstract：:The suitability of Beidler's mixture equation for mixtures of sucrose and maltitol as well as for mixtures of sucrose and aspartame was examined in the presence of an orange aroma. The mean scores for the attribute sweet remained constant for each combination of sucrose and maltitol and for each combination of sucrose...

journal_title：Chemical senses

authors： Nahon DF,Roozen JP,de Graaf C

更新日期：1998-02-01 00:00:00

abstract：:Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...

journal_title：Chemical senses

authors： Schwartz C,Chabanet C,Szleper E,Feyen V,Issanchou S,Nicklaus S

更新日期：2017-09-01 00:00:00

abstract：:We report 2 experiments designed to investigate the effect of people's prior beliefs concerning specific color-flavor associations on their ability to discriminate the flavor of colored sugar-coated chocolate sweets. The participants in our study judged whether pairs of Smarties had the same flavor or not. In our firs...

journal_title：Chemical senses

authors： Levitan CA,Zampini M,Li R,Spence C

更新日期：2008-06-01 00:00:00

abstract：:The perceived bitterness intensity for bitter solutions of propylthiouracil (PROP), sucrose octa-acetate (SOA), quinine HCl and caffeine were examined in a genetically informative sample of 392 females and 313 males (mean age of 17.8 +/- 3.1 years), including 62 monozygotic and 131 dizygotic twin pairs and 237 sib pai...

journal_title：Chemical senses

authors： Hansen JL,Reed DR,Wright MJ,Martin NG,Breslin PA

更新日期：2006-06-01 00:00:00

abstract：:Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...

journal_title：Chemical senses

authors： Manoel D,Makhlouf M,Scialdone A,Saraiva LR

更新日期：2019-01-01 00:00:00

abstract：:It was recently shown that in some subjects capsaicin can evoke bitterness as well as burning and stinging, particularly in the circumvallate (CV) region of the tongue. Because perception of bitterness from capsaicin is characterized by large individual differences, the main goal of the present study was to learn whet...

journal_title：Chemical senses

authors： Green BG,Hayes JE

更新日期：2004-01-01 00:00:00

abstract：:Insect odorant receptors (ORs) function as heteromeric odorant-gated ion channels consisting of a conserved coreceptor, Orco, and an odorant-sensitive tuning subunit. Although some OR modulators have been identified, an extended library of pharmacological tools is currently lacking and would aid in furthering our unde...

journal_title：Chemical senses

authors： Pask GM,Bobkov YV,Corey EA,Ache BW,Zwiebel LJ

更新日期：2013-03-01 00:00:00

abstract：:Regarding the chemotaxis of sperms, new insights have been gained during the last 20 years. Olfactory receptors are expressed on the flagellar midpiece of human spermatogenic cells. One of them, OR1D2, is also expressed in the olfactory epithelium. This receptor has been suggested to play a role in sperm chemotaxis an...

journal_title：Chemical senses

authors： Sinding C,Kemper E,Spornraft-Ragaller P,Hummel T

更新日期：2013-06-01 00:00:00

abstract：:To assess the feasibility of using odors as a potential mechanism for treating sleep apnea, we set out to test the hypothesis that odorants delivered during sleep would modify respiratory patterns without inducing arousal or wake in healthy sleepers. We used 2 mildly trigeminal odorants: the pleasant lavender and unpl...

journal_title：Chemical senses

authors： Arzi A,Sela L,Green A,Givaty G,Dagan Y,Sobel N

更新日期：2010-01-01 00:00:00

abstract：:Glucose is a universal phagostimulant in many animal species, including the cockroach Blattella germanica. However, some natural populations of B. germanica have been found that are behaviorally deterred from eating glucose. In dose-response studies, glucose was a powerful phagostimulant for wild-type cockroaches, but...

journal_title：Chemical senses

authors： Wada-Katsumata A,Silverman J,Schal C

更新日期：2011-09-01 00:00:00

abstract：:Electrophysiological responses of olfactory receptor neurons in both male and female silkmoths (Bombyx mori) were investigated. In both sexes, the G-protein activator sodium fluoride and 1,2-dioctanoyl-sn-glycerol, a membrane-permeable analog of the protein kinase C activator diacylglycerol, elicited nerve impulse res...

journal_title：Chemical senses

authors： Pophof B,Van der Goes van Naters W

更新日期：2002-06-01 00:00:00

abstract：:Organotypic cultures of the mouse olfactory epithelium connected to the olfactory bulb were obtained with the roller tube technique from postnatal mice aged between 13 and 66 days. To test the functionality of the cultures, we measured electroolfactograms (EOGs) at different days in vitro (DIV), up to 7 DIV, and we co...

journal_title：Chemical senses

authors： Pinato G,Rievaj J,Pifferi S,Dibattista M,Masten L,Menini A

更新日期：2008-04-01 00:00:00

abstract：:Eating under distracted conditions such as viewing television is associated with overeating and weight gain. Following evidence from earlier findings, in this issue Hoffman-Hensel et al. report a study in which they investigated the influence of distraction on intensity perception of low and high caloric food odors an...

journal_title：Chemical senses

authors： Veldhuizen MG

更新日期：2017-10-31 00:00:00

abstract：:Rats trained on a series of 16 novel 2-odor discrimination tasks using a 10-s intertrial interval (ITI) rapidly improved in performance and made only 0-3 errors by the end of the test series. They were then tested on other novel pairs of odors, but with a 10- and a 30-min interval between trials. There was no decremen...

journal_title：Chemical senses

authors： Lovelace CT,Slotnick BM

更新日期：1995-04-01 00:00:00

abstract：:Although the honeybee (Apis mellifera) is one of the world most studied insects, the chemical compounds used in nestmate recognition, remains an open question. By exploiting the error prone recognition system of the honeybee, coupled with genotyping, we studied the correlation between cuticular hydrocarbon (CHC) profi...

journal_title：Chemical senses

authors： Pradella D,Martin SJ,Dani FR

更新日期：2015-11-01 00:00:00

abstract：:The capacity of the peripheral olfactory system to recover after injury has not been thoroughly explored. P2-IRES-tauLacZ mice were exposed to methyl bromide, which causes epithelial damage and kills 90% of the P2 neurons. With subsequent neuronal regeneration, P2 neurons recover within their usual territory to equal ...

journal_title：Chemical senses

authors： Holbrook EH,Iwema CL,Peluso CE,Schwob JE

更新日期：2014-09-01 00:00:00