Responses of cultured rat trigeminal ganglion neurons to bitter tastants.

abstract：:Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight ...

journal_title：Chemical senses

authors： Proserpio C,Laureati M,Bertoli S,Battezzati A,Pagliarini E

更新日期：2016-02-01 00:00:00

abstract：:In this study, 40 Japanese, 44 German and 39 Mexican women were presented with 18 everyday odorants. They were asked to rate them for intensity on a six-point scale from not detectable to very strong, for pleasantness on an 11-point scale from -5, to neutral at 0, to +5, and for familiarity on a six-point scale from c...

journal_title：Chemical senses

authors： Distel H,Ayabe-Kanamura S,Martínez-Gómez M,Schicker I,Kobayakawa T,Saito S,Hudson R

更新日期：1999-04-01 00:00:00

abstract：:Genetic variation in oral sensation presumably influences ingestive behaviors through sensations arising from foods and beverages. Here, we investigated the influence of taste phenotype [6-n-propylthiouracil (PROP) bitterness, fungiform papillae (FP) density] on sweet and creamy sensations from sugar/fat mixtures. Sev...

journal_title：Chemical senses

authors： Hayes JE,Duffy VB

更新日期：2007-03-01 00:00:00

abstract：:In 20 normal and four anosmic participants, instantaneous inhalation and exhalation flow rates were recorded in response to 15 s stimulations with clean air or propionic acid concentrations (0.16, 1.14, 8.22 and 59.15 p.p.m., v/v) that ranged from peri-threshold for normals to clearly supra-threshold for anosmics. Eac...

journal_title：Chemical senses

authors： Walker JC,Kendal-Reed M,Hall SB,Morgan WT,Polyakov VV,Lutz RW

更新日期：2001-05-01 00:00:00

abstract：:When people misidentify everyday odors, as they often do, their errors may conceivably lie in faulty perceptions or in faulty access to the names. Discussions of the matter usually focus on the latter, as if people had no problems with perceptual accuracy. (The problem of faulty access may get attention because its hi...

journal_title：Chemical senses

authors： Cain WS,Potts BC

更新日期：1996-02-01 00:00:00

abstract：:Clinically, olfaction can fail in any of three ways: (i) decreased sensitivity (hyposmia, anosmia) and two types of distortion (dysosmia); (ii) distorted quality of an odorant stimulation (troposmia); (iii) perceived odor when no odorant is present (phantosmia, hallucination). The distortions are usually much more ups...

journal_title：Chemical senses

authors： Leopold D

更新日期：2002-09-01 00:00:00

abstract：:Previous studies on taste acceptance have been conducted taste-by-taste and with a cross-sectional design. The aim of this study was to longitudinally evaluate the acceptance of sweet, salty, bitter, sour and umami solutions, and a fat emulsion comparatively in a birth cohort from 3 to 20 months old. The acceptance of...

journal_title：Chemical senses

authors： Schwartz C,Chabanet C,Szleper E,Feyen V,Issanchou S,Nicklaus S

更新日期：2017-09-01 00:00:00

abstract：:The role of odors in the long-distance navigation of birds has elicited intense debate for more than half a century. Failure to resolve many of the issues fueling this debate is due at least in part to the absence of controls for a variety of non-specific effects that odors have on the navigational process. The presen...

journal_title：Chemical senses

authors： Jorge PE,Marques PAM,Pinto BV,Phillips JB

更新日期：2016-11-01 00:00:00

abstract：:The present study demonstrated that 100 microM amiloride serves as an ineffective conditioned taste stimulus in a taste aversion paradigm. Even if amiloride has a detectable taste, it's unlikely that its behavioral effects in salt mixture experiments are due to its inherent taste quality. ...

journal_title：Chemical senses

authors： Markison S,Spector AC

更新日期：1995-10-01 00:00:00

abstract：:The strong bond that is formed between ewe and lamb after parturition is important for lamb survival. Evidence exists that the ewe mainly employs olfactory recognition cues to distinguish her lamb from other lambs in the flock. We have found that volatile organic compounds in the wool of Merino lambs that presumably c...

journal_title：Chemical senses

authors： Viviers MZ,Burger BV,le Roux NJ,Morris J,le Roux M

更新日期：2014-03-01 00:00:00

abstract：:The state of the art in aroma analysis is reviewed with emphasis on aroma-recombination studies using synthetic blends of odorants (aroma models) which have been prepared on the basis of analytical data. The model that matches the original aroma is the starting material for omission experiments which are performed to ...

journal_title：Chemical senses

authors： Grosch W

更新日期：2001-06-01 00:00:00

abstract：:Glutathione, a natural substance, acts on calcium receptors on the tongue and is known to enhance basic taste sensations. However, the effects of glutathione on brain activity associated with taste sensation on the tongue have not been determined under standardized taste delivery conditions. In this study, we investig...

journal_title：Chemical senses

authors： Goto TK,Yeung AW,Tanabe HC,Ito Y,Jung HS,Ninomiya Y

更新日期：2016-09-01 00:00:00

abstract：:It was recently shown that in some subjects capsaicin can evoke bitterness as well as burning and stinging, particularly in the circumvallate (CV) region of the tongue. Because perception of bitterness from capsaicin is characterized by large individual differences, the main goal of the present study was to learn whet...

journal_title：Chemical senses

authors： Green BG,Hayes JE

更新日期：2004-01-01 00:00:00

abstract：:The stimuli used in taste research are usually considered to be odourless. This was tested in two experiments with aqueous solutions of two representative compounds for each of the five taste qualities including umami. In the first experiment elderly and young subjects rated the intensity and pleasantness of three con...

journal_title：Chemical senses

authors： Mojet J,Köster EP,Prinz JF

更新日期：2005-01-01 00:00:00

abstract：:Restriction of dietary sodium during gestation has major effects on taste function and anatomy in the offspring. The chorda tympani nerve of offspring that are maintained on sodium-reduced chow throughout life (NaDep) has reduced neurophysiological responses to sodium and altered morphology of its terminal field in th...

journal_title：Chemical senses

authors： Sollars SI,Hill DL

更新日期：2000-12-01 00:00:00

abstract：:Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to indu...

journal_title：Chemical senses

authors： Ramaekers MG,Verhoef A,Gort G,Luning PA,Boesveldt S

更新日期：2016-02-01 00:00:00

abstract：:Small soluble proteins, belonging to the lipocalin family are secreted in large amounts by tongue von Ebner's glands and lachrymal glands. In humans, the lingual protein, called VEG, and the lachrymal protein, called tear prealbumin, have shown identical cDNA sequences. In the pig, we have purified homodimeric protein...

journal_title：Chemical senses

authors： Garibotti M,Christiansen H,Schmale H,Pelosi P

更新日期：1995-02-01 00:00:00

abstract：:Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...

journal_title：Chemical senses

authors： Georgiopoulos C,Witt ST,Haller S,Dizdar N,Zachrisson H,Engström M,Larsson EM

更新日期：2018-07-05 00:00:00

abstract：:Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...

journal_title：Chemical senses

authors： Manoel D,Makhlouf M,Scialdone A,Saraiva LR

更新日期：2019-01-01 00:00:00

abstract：:There is no natural physical continuum for odor quality along which an odor quality discrimination (OQD) threshold can be measured. In an attempt to overcome this problem, the substitution-reciprocity (SURE) method defines a framework for the measurement of an OQD threshold. More specifically, it (i) defines a thresho...

journal_title：Chemical senses

authors： Olsson MJ,Cain WS

更新日期：2000-10-01 00:00:00

abstract：:Organotypic cultures of the mouse olfactory epithelium connected to the olfactory bulb were obtained with the roller tube technique from postnatal mice aged between 13 and 66 days. To test the functionality of the cultures, we measured electroolfactograms (EOGs) at different days in vitro (DIV), up to 7 DIV, and we co...

journal_title：Chemical senses

authors： Pinato G,Rievaj J,Pifferi S,Dibattista M,Masten L,Menini A

更新日期：2008-04-01 00:00:00

abstract：:Flavor and texture contribute to the perception of creaminess in dairy products, but the nature of this interaction is not well understood. Previous studies on the genetic ability to perceive the bitter compound 6-n-propylthiouracil (PROP) reveal the existence of individual differences in creaminess perception. The ob...

journal_title：Chemical senses

authors： Kirkmeyer SV,Tepper BJ

更新日期：2003-07-01 00:00:00

abstract：:Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

journal_title：Chemical senses

authors： Kotrschal K,Krautgartner WD,Hansen A

更新日期：1997-04-01 00:00:00

abstract：:The perceived bitterness intensity for bitter solutions of propylthiouracil (PROP), sucrose octa-acetate (SOA), quinine HCl and caffeine were examined in a genetically informative sample of 392 females and 313 males (mean age of 17.8 +/- 3.1 years), including 62 monozygotic and 131 dizygotic twin pairs and 237 sib pai...

journal_title：Chemical senses

authors： Hansen JL,Reed DR,Wright MJ,Martin NG,Breslin PA

更新日期：2006-06-01 00:00:00

abstract：:The sense of smell deteriorates in normal aging, but the underling mechanisms are still elusive. Here we investigated age-related alterations in expression patterns of odorant receptor (OR) genes and functional properties of olfactory sensory neurons (OSNs)-2 critical factors that define the odor detection threshold i...

journal_title：Chemical senses

authors： Lee AC,Tian H,Grosmaitre X,Ma M

更新日期：2009-10-01 00:00:00

abstract：:The purpose of this study was to determine the degree to which the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid (Na-PMP) reduced sweet intensity ratings of 15 sweeteners in mixtures. Na-PMP has been approved for use in confectionary/frostings, soft candy and snack products in the USA at concentrations up to 15...

journal_title：Chemical senses

authors： Schiffman SS,Booth BJ,Sattely-Miller EA,Graham BG,Gibes KM

更新日期：1999-08-01 00:00:00

abstract：:Anosmia affects the western world population, mostly the elderly, reaching to 5% in subjects over the age of 45 years and strongly lowering their quality of life. A smaller minority (about 0.01%) is born without a sense of smell, afflicted with congenital general anosmia (CGA). No causative genes for human CGA have be...

journal_title：Chemical senses

authors： Feldmesser E,Bercovich D,Avidan N,Halbertal S,Haim L,Gross-Isseroff R,Goshen S,Lancet D

更新日期：2007-01-01 00:00:00

abstract：:The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mi...

journal_title：Chemical senses

authors： Kass MD,Guang SA,Moberly AH,McGann JP

更新日期：2016-02-01 00:00:00

abstract：:Taste sensitivity plays a major role in controlling feeding behavior, and alterations in feeding habit induced by changes in taste sensitivity can drive speciation. We investigated variability in taste preferences in wild-derived inbred lines from the Drosophila melanogaster Genetic Reference Panel. Preferences for di...

journal_title：Chemical senses

authors： Uchizono S,Tanimura T

更新日期：2017-05-01 00:00:00

abstract：:Our study was designed to examine how components of complex mixtures can inhibit the binding of other components to receptor sites in the olfactory system of the spiny lobster Panulirus argus. Biochemical binding assays were used to study how two- to six-component mixtures inhibit binding of the radiolabeled odorants ...

journal_title：Chemical senses

authors： Gentilcore LR,Derby CD

更新日期：1998-06-01 00:00:00