Sex-specific responses to urinary chemicals by the mouse vomeronasal organ.

abstract：:The purpose of this study was to determine the degree to which the sodium salt of +/-2-(4-methoxyphenoxy)propanoic acid (Na-PMP) reduced sweet intensity ratings of 15 sweeteners in mixtures. Na-PMP has been approved for use in confectionary/frostings, soft candy and snack products in the USA at concentrations up to 15...

journal_title：Chemical senses

authors： Schiffman SS,Booth BJ,Sattely-Miller EA,Graham BG,Gibes KM

更新日期：1999-08-01 00:00:00

abstract：:Studying olfaction with functional magnetic resonance imaging (fMRI) poses various methodological challenges. This study aimed to investigate the effects of stimulation length and repetition time (TR) on the activation pattern of 4 olfactory brain regions: the anterior and the posterior piriform cortex, the orbitofron...

journal_title：Chemical senses

authors： Georgiopoulos C,Witt ST,Haller S,Dizdar N,Zachrisson H,Engström M,Larsson EM

更新日期：2018-07-05 00:00:00

abstract：:The primary olfactory centre, the antennal lobe of Heliothis virescens moths, contains 62 glomeruli which process plant odour information and four male-specific glomeruli which form the macroglomerular complex, involved in processing information about pheromone and interspecific signals. Using calcium imaging, we reco...

journal_title：Chemical senses

authors： Skiri HT,Galizia CG,Mustaparta H

更新日期：2004-03-01 00:00:00

abstract：:The importance of stimulus timing and location on the perceptual integration of taste and odour was studied based on a sub-threshold methodology. From a panel of 16 people, 12 showed the integration effect previously reported while 4 showed no effect. The experiment was repeated using retronasal and orthonasal deliver...

journal_title：Chemical senses

authors： Pfeiffer JC,Hollowood TA,Hort J,Taylor AJ

更新日期：2005-09-01 00:00:00

abstract：:The sweet taste of sucrose acts as an analgesic, whereas the taste of a bitter substance decreases pain tolerance. The present experiment explores the analgesic effect of a complex taste and asks how adding cocoa, a substance often associated with sweet foods but that has a bitter taste, to a sucrose solution affects ...

journal_title：Chemical senses

authors： Eggleston K,White TL,Sheehe PR

更新日期：2010-05-01 00:00:00

abstract：:Adaptation techniques have traditionally been employed in sensory physiology and psychology to characterize afferent pathways and to dissect the quantitative and, to a lesser degree, the qualitative aspects of perception. We continue to explore the individual differences in olfactory capabilities among subjects initia...

journal_title：Chemical senses

authors： O'Connell RJ,Stevens DA,Zogby LM

更新日期：1994-06-01 00:00:00

abstract：:Biological detectors such as the human nose or an insect antenna represent extremely attractive detectors for gas chromatography (GC) since they are specifically tuned to perceive biologically relevant compounds. However, these detectors are nonlinear, noisy and often perform poorly under standard GC conditions since ...

journal_title：Chemical senses

authors： Gouinguené S,de Cruz I,van der Pers J,Wadhams L,Marion-Poll F

更新日期：1998-12-01 00:00:00

abstract：:Ability to perceive the bitter compound phenylthiocarbamide (PTC) is inherited via a dominant "taster" allele of the TAS2R38 gene, whereas inability is inherited via a recessive "non-taster" allele. This raises a question: Is the non-taster allele functionless, or does it mediate perception of compounds other than PTC...

journal_title：Chemical senses

authors： Wooding SP

更新日期：2018-08-24 00:00:00

abstract：:Chemosensory receptors, including odor, taste, and vomeronasal receptors, comprise the largest group of G protein-coupled receptors (GPCRs) in the mammalian genome. However, little is known about the molecular determinants that are critical for the detection and discrimination of ligands by most of these receptors. Th...

journal_title：Chemical senses

authors： Nie Y,Hobbs JR,Vigues S,Olson WJ,Conn GL,Munger SD

更新日期：2006-07-01 00:00:00

abstract：:Honeybees rely on nectar as their main source of carbohydrates. Sucrose, glucose, and fructose are the main components of plant nectars. Intriguingly, honeybees express only 3 putative sugar receptors (AmGr1, AmGr2, and AmGr3), which is in stark contrast to many other insects and vertebrates. The sugar receptors are o...

journal_title：Chemical senses

authors： Değirmenci L,Geiger D,Rogé Ferreira FL,Keller A,Krischke B,Beye M,Steffan-Dewenter I,Scheiner R

更新日期：2020-11-07 00:00:00

abstract：:In this issue of Chemical Senses, Münch et al. present a thorough analysis of how mixtures of odorants interact with olfactory receptors (ORs) borne by olfactory receptor neurons (ORNs). Using fruit fly ORNs expressing the receptor OR22a, they provide a clear example of mixture interaction and confirm that the respons...

journal_title：Chemical senses

authors： Rospars JP

更新日期：2013-05-01 00:00:00

abstract：:This study determined taste thresholds for copper as its speciation was varied among free cupric ion, complexed cupric ion, and precipitated cupric particles. The impact of copper chemistry on taste is important as copper is added to many beverages and can be present in drinking water as a natural mineral or due to co...

journal_title：Chemical senses

authors： Cuppett JD,Duncan SE,Dietrich AM

更新日期：2006-09-01 00:00:00

abstract：:The Grueneberg ganglion (GG) in the vestibule of the anterior nasal cavity is considered as an olfactory subcompartment based on expression of the olfactory marker protein (OMP) and axonal projection to the olfactory bulb. Searching for olfactory receptors present in the GG, it has been observed recently that V2r83, a...

journal_title：Chemical senses

authors： Fleischer J,Schwarzenbacher K,Breer H

更新日期：2007-07-01 00:00:00

abstract：:The effect of color on orthonasal and retronasal odor intensities was investigated. When odorants were smelled orthonasally (i.e., through the nostrils), color enhanced odor intensity ratings, consistent with previous reports. However, when odorants were smelled retronasally (i.e., the odorous solution was put in the ...

journal_title：Chemical senses

authors： Koza BJ,Cilmi A,Dolese M,Zellner DA

更新日期：2005-10-01 00:00:00

abstract：:When the glossopharyngeal (GP) nerve of the frog was stimulated electrically, electropositive slow potentials were recorded from the tongue surface and depolarizing slow potentials from taste cells in the fungiform papillae. The amplitude of the slow potentials was stimulus strength- and the frequency-dependent. Gener...

journal_title：Chemical senses

authors： Sato T,Toda K,Miyamoto T,Okada Y,Fujiyama R

更新日期：2000-10-01 00:00:00

abstract：:Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a ...

journal_title：Chemical senses

authors： Manoel D,Makhlouf M,Scialdone A,Saraiva LR

更新日期：2019-01-01 00:00:00

abstract：:An apparent plasticity in glucose sensitivity was first noted while studying human taste variants, but the experimental design did not rule out regression to the mean. Since then, a human taste induction hypothesis that sensitivity for a taste stimulus increases with repeated exposure to it has been supported first by...

journal_title：Chemical senses

authors： Gonzalez KM,Peo C,Livdahl T,Kennedy LM

更新日期：2008-02-01 00:00:00

abstract：:Anosmia affects the western world population, mostly the elderly, reaching to 5% in subjects over the age of 45 years and strongly lowering their quality of life. A smaller minority (about 0.01%) is born without a sense of smell, afflicted with congenital general anosmia (CGA). No causative genes for human CGA have be...

journal_title：Chemical senses

authors： Feldmesser E,Bercovich D,Avidan N,Halbertal S,Haim L,Gross-Isseroff R,Goshen S,Lancet D

更新日期：2007-01-01 00:00:00

abstract：:To date, most studies on the relationship between chemosensory performance and quality of life have focused on orthonasal measures of olfactory function. In the current investigation, we examined the predictive value of orthonasal and flavor identification indices of olfactory function on a wide spectrum of health and...

journal_title：Chemical senses

authors： Oleszkiewicz A,Park D,Resler K,Draf J,Schulze A,Zang Y,Hähner A,Hummel T

更新日期：2019-07-17 00:00:00

abstract：:Cigarettes are an often-used consumer product, and flavor is an important determinant of their product appeal. Cigarettes with strong nontobacco flavors are popular among young people, and may facilitate smoking initiation. Discriminating flavors in tobacco is important for regulation purposes, for instance to set upp...

journal_title：Chemical senses

authors： Krüsemann EJ,Cremers JW,Visser WF,Punter PH,Talhout R

更新日期：2017-03-01 00:00:00

abstract：:Transcriptional regulation is an important mechanism by which neurons adapt to environmental stimuli. The indirect dopamine agonists, amphetamine and cocaine have been shown to induce expression of immediate early genes, such as c-fos, and neuropeptide genes, such as prodynorphin in the rat striatum. Here we show that...

journal_title：Chemical senses

authors： Hyman SE,Cole RL,Konradi C,Kosofsky BE

更新日期：1995-04-01 00:00:00

abstract：:Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

journal_title：Chemical senses

authors： Kotrschal K,Krautgartner WD,Hansen A

更新日期：1997-04-01 00:00:00

abstract：:It has been proposed that memory for odors does not have a short-term (or working) memory system. The distinction between short- and long-term memory in other sensory modalities has been generally supported by three main lines of evidence: capacity differences between the proposed systems, evidence of differential cod...

journal_title：Chemical senses

authors： White TL

更新日期：1998-08-01 00:00:00

abstract：:The stimuli used in taste research are usually considered to be odourless. This was tested in two experiments with aqueous solutions of two representative compounds for each of the five taste qualities including umami. In the first experiment elderly and young subjects rated the intensity and pleasantness of three con...

journal_title：Chemical senses

authors： Mojet J,Köster EP,Prinz JF

更新日期：2005-01-01 00:00:00

abstract：:The perceived bitterness intensity for bitter solutions of propylthiouracil (PROP), sucrose octa-acetate (SOA), quinine HCl and caffeine were examined in a genetically informative sample of 392 females and 313 males (mean age of 17.8 +/- 3.1 years), including 62 monozygotic and 131 dizygotic twin pairs and 237 sib pai...

journal_title：Chemical senses

authors： Hansen JL,Reed DR,Wright MJ,Martin NG,Breslin PA

更新日期：2006-06-01 00:00:00

abstract：:The perception of sweetness and flavour were studied in viscous solutions containing 50 g/l sucrose, 100 p.p.m. iso-amyl acetate and varying concentrations of three hydrocolloid thickeners (guar gum, lambda-carrageenan and hydroxypropylmethyl cellulose). Zero-shear viscosity of the samples ranged from 1 to 5000 mPas. ...

journal_title：Chemical senses

authors： Cook DJ,Hollowood TA,Linforth RS,Taylor AJ

更新日期：2003-01-01 00:00:00

abstract：:Two experiments examined time/concentration trading for the detection of carbon dioxide, an irritant with little or no odor. Experiment 1 employed the nasal lateralization method: subjects attempted to determine which nostril received carbon dioxide and which received pure air when presented simultaneously. Experiment...

journal_title：Chemical senses

authors： Wise PM,Radil T,Wysocki CJ

更新日期：2004-02-01 00:00:00

abstract：:A healthy taste system is important to the maintenance of nutrition and overall quality of life, and taste disorders are associated with many inflammatory states. We previously determined the immune cells in normal human gustatory tissue; they are predominantly dendritic cells and CD4 T cells with a few macrophages an...

journal_title：Chemical senses

authors： Feng P,Wang H,Feldman RS,Pribitkin EA,Breslin PA

更新日期：2010-07-01 00:00:00

abstract：:Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally (IP) into C57BL/6 mi...

journal_title：Chemical senses

authors： Peng WH,Chau YP,Lu KS,Kung HN

更新日期：2016-01-01 00:00:00

abstract：:To analyze the mechanisms of perception and processing of pheromonal signals in vitro, we previously developed a new culture system for vomeronasal receptor neurons (VRNs), referred to as the vomeronasal pocket (VN pocket). However, very few VRNs were found to express the olfactory marker protein (OMP) and to have pro...

journal_title：Chemical senses

authors： Moriya-Ito K,Osada T,Ishimatsu Y,Muramoto K,Kobayashi T,Ichikawa M

更新日期：2005-02-01 00:00:00