Arecoline Alters Taste Bud Cell Morphology, Reduces Body Weight, and Induces Behavioral Preference Changes in Gustatory Discrimination in C57BL/6 Mice.

abstract：:Ten SW.B6 SOA nontaster strains congenic with the SWR/J SOA taster inbred strain were bred via repeated backcross-intercross cycles, with selection for nontasting in each cycle. Preference ratio distributions and phenotypic proportions across cycles at 0.1 mM SOA were consistent with monogenic predictions. The SW.B6 m...

journal_title：Chemical senses

authors： Harder DB,Gannon KS,Whitney G

更新日期：1996-10-01 00:00:00

abstract：:Brazzein, a 54 residue sweet-tasting protein, is thought to participate in a multipoint binding interaction with the sweet taste receptor. Proposed sites for interaction with the receptor include 2 surface loops and the disulfide bond that connects the N- and C-termini. However, the importance of each site is not well...

journal_title：Chemical senses

authors： Dittli SM,Rao H,Tonelli M,Quijada J,Markley JL,Max M,Assadi-Porter F,Maillet E

更新日期：2011-11-01 00:00:00

abstract：:The primary olfactory centre, the antennal lobe of Heliothis virescens moths, contains 62 glomeruli which process plant odour information and four male-specific glomeruli which form the macroglomerular complex, involved in processing information about pheromone and interspecific signals. Using calcium imaging, we reco...

journal_title：Chemical senses

authors： Skiri HT,Galizia CG,Mustaparta H

更新日期：2004-03-01 00:00:00

abstract：:Evidence suggests that women outperform men in core aspects of odor perception, and sex hormones may play a significant role in moderating this effect. The gender-affirming treatment (GAT) of transgender persons constitutes a powerful natural experiment to study the psychological and behavioral effects of high dosages...

journal_title：Chemical senses

authors： Kranz GS,Kaufmann U,Lanzenberger R

更新日期：2020-01-01 00:00:00

abstract：:Prior research has documented a modulating effect of taste on swallowing. We hypothesized that presentation of tastant stimuli would be a significant variable in swallowing-respiratory coordination, duration of oral bolus preparation, and submental muscle contraction. Twenty-three healthy females were presented with 1...

journal_title：Chemical senses

authors： Leow LP,Huckabee ML,Sharma S,Tooley TP

更新日期：2007-02-01 00:00:00

abstract：:Secondary epidermal solitary chemosensory cells (SCCs) are widespread among the primary aquatic vertebrates. They resemble taste bud sensory cells in fine structure and may be innervated from facial or spinal nerves. According to previous studies, SCCs may constitute a water sampling system in the contexts of predator...

journal_title：Chemical senses

authors： Kotrschal K,Krautgartner WD,Hansen A

更新日期：1997-04-01 00:00:00

abstract：:The experiments had 2 main goals: 1) to add to the sparse literature on how retronasal aromas interact with bitter tastes, and 2) to determine whether modulation of taste intensity by aroma depends on temporal contiguity, as one might expect if flavor interactions depend on cross-modal binding (similar to object perce...

journal_title：Chemical senses

authors： Isogai T,Wise PM

更新日期：2016-09-01 00:00:00

abstract：:Strong electrical stimulation (ES) of the frog glossopharyngeal (GP) efferent nerve induced slow depolarizing potentials (DPs) in taste cells under hypoxia. This study aimed to elucidate whether the slow DPs were postsynaptically induced in taste cells. After a block of parasympathetic nerve (PSN) ganglia by tubocurar...

journal_title：Chemical senses

authors： Sato T,Nishishita K,Okada Y,Toda K

更新日期：2007-05-01 00:00:00

abstract：:Olfactory perception is highly variable from one person to another, as a function of individual and contextual factors. Here, we investigated the influence of 2 important factors of variation: culture and semantic information. More specifically, we tested whether cultural-specific knowledge and presence versus absence...

journal_title：Chemical senses

authors： Ferdenzi C,Joussain P,Digard B,Luneau L,Djordjevic J,Bensafi M

更新日期：2017-01-01 00:00:00

abstract：:When one taste (masker) is strong enough, it can completely mask another task (target) of different quality. How strong the masker must be to do this depends on how strong the target is. As the target concentration is increased, the masking concentration must be increased, too, but in ever-increasing proportion. To qu...

journal_title：Chemical senses

authors： Stevens JC

更新日期：1996-04-01 00:00:00

abstract：:The distribution of NADPH-diaphroase activity was examined in the accessory olfactory bulb of the rat using a direct histochemical technique. Labeled fibers and somata were found in all layers of the accessory olfactory bulb. The entire vomeronasal nerve and all vomeronasal glomeruli were strongly labeled, contrary to...

journal_title：Chemical senses

authors： Porteros A,Alonso JR,Arévalo R,García-Ojeda E,Crespo C,Aijón J

更新日期：1994-10-01 00:00:00

abstract：:Associative plasticity is a basic essential attribute of nervous systems. As shown by numerous reports, Drosophila is able to establish simple forms of appetitive and aversive olfactory associations at both larval and adult stages. Whereas most adult studies on aversive learning employed electric shock as a negative r...

journal_title：Chemical senses

authors： Pauls D,Pfitzenmaier JE,Krebs-Wheaton R,Selcho M,Stocker RF,Thum AS

更新日期：2010-05-01 00:00:00

abstract：:The importance of stimulus timing and location on the perceptual integration of taste and odour was studied based on a sub-threshold methodology. From a panel of 16 people, 12 showed the integration effect previously reported while 4 showed no effect. The experiment was repeated using retronasal and orthonasal deliver...

journal_title：Chemical senses

authors： Pfeiffer JC,Hollowood TA,Hort J,Taylor AJ

更新日期：2005-09-01 00:00:00

abstract：:Natural odors occur as turbulent plumes resulting in spatially and temporally variable odor signals at the chemoreceptor cells. Concentrations can fluctuate widely within discrete packets of odor and individual packets are very intermittent and unpredictable. Chemoreceptor cells display the temporally dynamic properti...

journal_title：Chemical senses

authors： Moore PA

更新日期：1994-02-01 00:00:00

abstract：:A metacognitive perspective is utilized to elucidate why it is so difficult to name common odors and what characterizes the subjective knowledge people have about their actual odor knowledge. Odor-naming failures are often accompanied by strong feelings of knowing (FOK) or feelings of imminent retrieval of what it is ...

journal_title：Chemical senses

authors： Jönsson FU,Tchekhova A,Lönner P,Olsson MJ

更新日期：2005-05-01 00:00:00

abstract：:Lectin binding patterns in the olfactory bulb of the mouse were investigated using 12 biotinylated lectins. Three, with specificities for galactose, N-acetylgalactosamine and L-fucose, stained only the nervous and glomerular layers of the accessory olfactory bulb; four, with specificities for galactose or N-acetylgluc...

journal_title：Chemical senses

authors： Salazar I,Sánchez Quinteiro P,Lombardero M,Cifuentes JM

更新日期：2001-07-01 00:00:00

abstract：:In chum salmon captured at the coastal sea and the natal river, the magnitudes of the olfactory nerve responses to the amino acids after perfusion of the olfactory epithelium with artificial pond water (APW) were similar to those after perfusion with artificial sea water (ASW), although the concentrations of Na+, Cl- ...

journal_title：Chemical senses

authors： Shoji T,Fujita K,Ban M,Hiroi O,Ueda H,Kurihara K

更新日期：1994-12-01 00:00:00

abstract：:Glomeruli, neuropilar structures composed of olfactory receptor neuron (ORN) axon terminals and central neuron dendrites, are a common feature of olfactory systems. Typically, ORN axons segregate into glomeruli based on odor specificity, making glomeruli the basic unit for initial processing of odorant information. De...

journal_title：Chemical senses

authors： Lipscomb BW,Tolbert LP

更新日期：2006-03-01 00:00:00

abstract：:Different odorant-binding proteins (OBPs) were isolated from total antennal homogenates of male and female Bombyx mori. Proteins were separated according to their isoelectric point by using preparative fast-flow isoelectrofocusing. Odorant-binding proteins were identified in immunoblots by antisera raised against the ...

journal_title：Chemical senses

authors： Maida R,Proebstl T,Laue M

更新日期：1997-10-01 00:00:00

abstract：:The perception of sweetness and flavour were studied in viscous solutions containing 50 g/l sucrose, 100 p.p.m. iso-amyl acetate and varying concentrations of three hydrocolloid thickeners (guar gum, lambda-carrageenan and hydroxypropylmethyl cellulose). Zero-shear viscosity of the samples ranged from 1 to 5000 mPas. ...

journal_title：Chemical senses

authors： Cook DJ,Hollowood TA,Linforth RS,Taylor AJ

更新日期：2003-01-01 00:00:00

abstract：:Anosmia affects the western world population, mostly the elderly, reaching to 5% in subjects over the age of 45 years and strongly lowering their quality of life. A smaller minority (about 0.01%) is born without a sense of smell, afflicted with congenital general anosmia (CGA). No causative genes for human CGA have be...

journal_title：Chemical senses

authors： Feldmesser E,Bercovich D,Avidan N,Halbertal S,Haim L,Gross-Isseroff R,Goshen S,Lancet D

更新日期：2007-01-01 00:00:00

abstract：:Many rodents are now known to exhibit an obligate proteinuria that delivers urine-mediated chemosignals. In this paper, we explore the urinary proteins of the Roborovski hamster (Phodopus roborovskii). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of urine from individual male and female Roborovsk...

journal_title：Chemical senses

authors： Turton MJ,Robertson DH,Smith JR,Hurst JL,Beynon RJ

更新日期：2010-10-01 00:00:00

abstract：:We have previously modeled the interaction of the sweet protein brazzein with the extracellular domains of the sweet taste receptor. Here, we describe the application of that model to the design of 12 new highly potent analogs of brazzein. Eight of the 12 analogs have higher sweetness potency than wild-type brazzein. ...

journal_title：Chemical senses

authors： Walters DE,Cragin T,Jin Z,Rumbley JN,Hellekant G

更新日期：2009-10-01 00:00:00

abstract：:The role of Ca(2+) in insect olfactory transduction was studied in the moth Spodoptera littoralis. Single sensillum recordings were made to investigate in vivo the role of sensillar Ca(2+) on the electrophysiological properties of sex pheromone responsive olfactory receptor neurons (ORNs). Lowering the sensillar Ca(2+...

journal_title：Chemical senses

authors： Pézier A,Acquistapace A,Renou M,Rospars JP,Lucas P

更新日期：2007-05-01 00:00:00

abstract：:The perceived bitterness intensity for bitter solutions of propylthiouracil (PROP), sucrose octa-acetate (SOA), quinine HCl and caffeine were examined in a genetically informative sample of 392 females and 313 males (mean age of 17.8 +/- 3.1 years), including 62 monozygotic and 131 dizygotic twin pairs and 237 sib pai...

journal_title：Chemical senses

authors： Hansen JL,Reed DR,Wright MJ,Martin NG,Breslin PA

更新日期：2006-06-01 00:00:00

abstract：:In rodents, the vomeronasal system controls social and sexual behavior. However, several mechanistic aspects of sensory signaling in the vomeronasal organ remain unclear. Here, we investigate the biophysical basis of a recently proposed vomeronasal signal transduction component-a Ca(2+)-activated Cl(-) current. As the...

journal_title：Chemical senses

authors： Untiet V,Moeller LM,Ibarra-Soria X,Sánchez-Andrade G,Stricker M,Neuhaus EM,Logan DW,Gensch T,Spehr M

更新日期：2016-10-01 00:00:00

abstract：:Olfactory function assessment is an important screening tool and also may differentiate Parkinson's disease (PD) patients from other parkinsonisms, including nondegenerative ones, such as, normal pressure hydrocephalus, vascular, drug induced, or infectious parkinsonism. Several authors in different countries have rep...

journal_title：Chemical senses

authors： Millar Vernetti P,Rossi M,Cerquetti D,Perez Lloret S,Merello M

更新日期：2016-01-01 00:00:00

abstract：:Studies over the last 8 years have identified 3 potential channels that appear to release ATP from Type II cells in response to taste stimuli. These studies have taken different methodological approaches but have all provided data supporting their candidate channel as the ATP release channel. These potential channels ...

journal_title：Chemical senses

authors： Medler KF

更新日期：2015-09-01 00:00:00

abstract：:There is no natural physical continuum for odor quality along which an odor quality discrimination (OQD) threshold can be measured. In an attempt to overcome this problem, the substitution-reciprocity (SURE) method defines a framework for the measurement of an OQD threshold. More specifically, it (i) defines a thresho...

journal_title：Chemical senses

authors： Olsson MJ,Cain WS

更新日期：2000-10-01 00:00:00

abstract：:During the past 2 decades, considerable progress has been made in the study of bird semiochemistry, and our goal was to review and evaluate this literature with particular emphasis on the volatile organic constituents. Indeed, since the importance of social chemosignaling in birds is becoming more and more apparent, t...

journal_title：Chemical senses

authors： Campagna S,Mardon J,Celerier A,Bonadonna F

更新日期：2012-01-01 00:00:00