A Case of Acantholytic Squamous Cell Carcinoma.

Abstract:

:Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on the sun-exposed areas of older aged individuals. Histologically, the tumor consists of a nodular, epidermal-derived proliferation that forms island-like structures. At least focally or sometimes extensively, the tumor cells shows a loss of cohesion within the central gland-like or tubular spaces. This tumor resembles the structure of eccrine neoplasms, but it is negative for dPAS, CEA and mucicarmine and it is only positive for EMA and cytokeratins. Herein we report a case of acantholytic squamous cell carcinoma that occurred on the face of an 82-year-old woman.

journal_name

Ann Dermatol

journal_title

Annals of dermatology

authors

Lim JY,Do MO,Kim SH,Hahm JH,Whang KK

doi

10.5021/ad.2008.20.4.267

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

267-70

issue

4

eissn

1013-9087

issn

2005-3894

journal_volume

20

pub_type

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