Low-Dose Systemic Methotrexate Therapy for Recalcitrant Alopecia Areata.

abstract：BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...

journal_title：Annals of dermatology

authors： Jin MH,Park SG,Hwang YL,Lee MH,Jeong NJ,Roh SS,Lee Y,Kim CD,Lee JH

更新日期：2012-02-01 00:00:00

abstract：:Lichen aureus is a rare type of chronic pigmented purpuric dermatosis. The eruptions consist of discrete or confluent golden to brownish lichenoid macules and papules, and are usually asymptomatic. Lichen aureus commonly occurs in young adults, but less frequently in children. We report the first case of multiple lich...

journal_title：Annals of dermatology

authors： Kim MJ,Kim BY,Park KC,Youn SW

更新日期：2009-11-01 00:00:00

abstract：:Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy. The nipple-areola complex (NAC) is an uncommon site for BCC to develop. BCCs in this region display more aggressive behavior and a greater potential to spread than when found i...

journal_title：Annals of dermatology

authors： Jung HJ,Jun JH,Kim HY,Lee SJ,Kim DW,Lee WJ,Jung JH

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role of growth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied and no controlled trials have been performed. OBJECTIVE:We evaluated the anti...

journal_title：Annals of dermatology

authors： Lee HJ,Lee EG,Kang S,Sung JH,Chung HM,Kim DH

更新日期：2014-10-01 00:00:00

abstract：:A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granul...

journal_title：Annals of dermatology

authors： Chiba T,Takahara M,Nakahara T,Fukagawa S,Takei K,Shono A,Kiryu H,Moroi Y,Furue M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Recently, the pulse-in-pulse mode of intense pulsed light (IPL) has been used increasingly for the treatment of melasma. OBJECTIVE:To observe the morphologic changes in the melanophore in adult zebrafish after irradiation with conventional and pulse-in-pulse IPL and Q-switched Nd:YAG (QSNY) laser. METHODS:...

journal_title：Annals of dermatology

authors： Ryu HJ,Lee JM,Jang HW,Park HC,Rhyu IJ,Kim IH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Short stature is sometimes seen in children with atopic dermatitis (AD); however, the topic has never been studied systematically. OBJECTIVE:The aim of this study was to show whether AD itself affects stature in children and to evaluate the influence of other relevant factors such as genetic background, die...

journal_title：Annals of dermatology

authors： Park MK,Park KY,Li K,Seo SJ,Hong CK

更新日期：2013-02-01 00:00:00

abstract：:Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walki...

journal_title：Annals of dermatology

authors： Chung J,Namkoong S,Sim JH,Lee JS,Hong SP,Kim MH,Park BC

更新日期：2011-10-01 00:00:00

abstract：:Acute localized exanthematous pustulosis (ALEP) is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 26-year-old woman presented with multiple erythematous pustules on her face, which had appeared th...

journal_title：Annals of dermatology

authors： Sim HS,Seol JE,Chun JS,Seo JK,Lee D,Sung HS

更新日期：2011-12-01 00:00:00

abstract：:Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp. ...

journal_title：Annals of dermatology

authors： Kim MS,Lee JH,Lee WM,Son SJ

更新日期：2010-08-01 00:00:00

abstract：Background:Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival. Objective:We sought to establish screening strategy for SUM in situ. Methods:We retrospectively reviewed medical records of 8 patients pathologically diagno...

journal_title：Annals of dermatology

authors： Lee JH,Park JH,Lee JH,Lee DY

更新日期：2018-02-01 00:00:00

abstract：Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...

journal_title：Annals of dermatology

authors： Kim BR,Yang S,Doh EJ,Choi CW,Youn SW

更新日期：2018-04-01 00:00:00

abstract：:Eosinophic fasciitis (EF) is an uncommon connective tissue disease characterized by scleroderma-like cutaneous changes, peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate (ESR). Typical histopathologic findings include chronic inflammatory infiltration affecting the deep fa...

journal_title：Annals of dermatology

authors： Chun JH,Lee KH,Sung MS,Park CJ

更新日期：2011-02-01 00:00:00

abstract：:Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-ass...

journal_title：Annals of dermatology

authors： Lim JS,Kim TM,Cho KH

更新日期：2017-10-01 00:00:00

abstract：:Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower b...

journal_title：Annals of dermatology

authors： Lee WJ,Park GH,Chang SE,Lee MW,Choi JH,Moon KC,Koh JK

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...

journal_title：Annals of dermatology

authors： Kim HS,Kim TW,Mun JH,Song M,Ko HC,Kim BS,Kim MB

更新日期：2014-08-01 00:00:00

abstract：:Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...

journal_title：Annals of dermatology

authors： Kim JE,Kim SC

更新日期：2018-08-01 00:00:00

abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...

journal_title：Annals of dermatology

authors： Choi MJ,Kim HS,Kim HO,Song KY,Park YM

更新日期：2010-05-01 00:00:00

abstract：:Actinomycotic infections are known to have an association with difficulties in diagnosis and treatment. These infections usually involve the head, neck, thorax, and abdomen. Actinomycosis of the upper lip is a rare condition and an important one as well, because it can imitate other diseases. As the initial impression...

journal_title：Annals of dermatology

authors： Lee YS,Sim HS,Lee SK

更新日期：2011-09-01 00:00:00

abstract：:Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-...

journal_title：Annals of dermatology

authors： Lee EA,Kim HS,Kim HO,Park YM

更新日期：2009-11-01 00:00:00

abstract：:Sarcoidosis is a systemic inflammatory disease of an unknown origin and it is characterized by the presence of noncaseating epitheloid cell granulomas in multiple organs. Herein we report on a case of cutaneous and pulmonary sarcoidosis that was associated with interferon alpha treatment for hepatitis C. A 39-year-old...

journal_title：Annals of dermatology

authors： Lee YB,Lee JI,Park HJ,Cho BK,Oh ST

更新日期：2011-05-01 00:00:00

abstract：:Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...

journal_title：Annals of dermatology

authors： Park J,Cho YS,Song KH,Lee JS,Yun SK,Kim HU

更新日期：2011-08-01 00:00:00

abstract：:Telogen effluvium is categorized in nonscarring alopecia, which shows scalp hair thinning and shedding diffusely resulting from inducing factors such as physiological stressful events and several acute or chronic diseases. It usually appears in female patients following parturition, as well as after febrile disease, m...

journal_title：Annals of dermatology

authors： Loh SH,Lew BL,Sim WY

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Several previous studies have suggested the improvement of atopic dermatitis (AD) in response to special fabrics. In particular, beneficial effects have been reported, following the use of anion textiles. OBJECTIVE:The purpose of this study is to evaluate the effectiveness and safety of an anion textile in ...

journal_title：Annals of dermatology

authors： Kim SH,Hwang SH,Hong SK,Seo JK,Sung HS,Park SW,Shin JH

更新日期：2012-11-01 00:00:00

abstract：:Blastomycosis-like pyoderma is a rare, vegetating skin lesion that is an unusual exaggerated tissue reaction possibly to prolonged primary or secondary bacterial infection. We report a case of blastomycosis-like pyoderma in a man with Down syndrome, diabetes mellitus and hypothyroidism who responsed poorly to conventi...

journal_title：Annals of dermatology

authors： Lee YS,Jung SW,Sim HS,Seo JK,Lee SK

更新日期：2011-08-01 00:00:00

abstract：:Vitiligo is a chronic disorder characterized by depigmented macules which can slowly enlarge with the concurrent development of new lesions. Although autologous suction blister epidermal grafting is an established technique for the treatment of recalcitrant, stable vitiligo, the donor tissue graft is not easy to fix a...

journal_title：Annals of dermatology

authors： Kim H,Kang JN,Hwang SH,Seo JK,Sung HS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease with a strong genetic basis. Cytokines such as tumor necrosis factor alpha (TNF-α), interleukins (ILs) such are IL-12 and IL-23, and interferon gamma (IFN-γ) are released from various inflammatory and resident cells, and have been implicated in the init...

journal_title：Annals of dermatology

authors： Popadic S,Savic E,Markovic M,Ramic Z,Medenica L,Pravica V,Spuran Z,Trajkovic V,Popadic D

更新日期：2015-04-01 00:00:00

abstract：:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...

journal_title：Annals of dermatology

authors： Yoon SY,Kwon HH,Jeon HC,Lee JH,Cho S

更新日期：2011-11-01 00:00:00

abstract：:Sweet's syndrome is a reactive dermatosis characterized clinically by fever, leukocytosis, and multiple, erythematous, painful plaques. Histopathologic examination reveals a band-like dense dermal inflammatory infiltrate composed mainly of neutrophils with papillary dermal edema, and no features of vasculitis. We repo...

journal_title：Annals of dermatology

authors： Lee GY,Do MO,Kim SH,Choi HY,Myung KB,Choi YW

更新日期：2009-08-01 00:00:00

abstract：:Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or ...

journal_title：Annals of dermatology

authors： Lin SS,Lee CC,Jang TN

更新日期：2014-04-01 00:00:00