Abstract：
:Intravascular lymphoma (IVL) is a rare disorder characterized by the presence of large neoplastic lymphoid cells restricted to the lumens of small vessels with a predilection for the skin and the central nervous system. While the vast majority of cases involving IVL are of B-cell lineage, the disease rarely affects the T-cell, the histiocytes, and the natural killer cells. We report a case of intravascular T-cell lymphoma (IVTL) associated with Epstein-Barr virus (EBV). A 23-year-old healthy woman presented with tender indurated erythematous patches with overlying telangiectasia on her right breast, abdomen, both the upper and the lower extremities and the back for 3 months. The pathology revealed an infiltration of dermal and subcutaneous vessels by large and atypical lymphoid cells with immunohistochemical features of the T-cell lineage with a cytotoxic phenotype (CD3+, CD8+, granzyme B+, TIA-1+, CD4-, CD5-, CD20-, CD56-). Interestingly, the DNA extracted from the skin biopsies demonstrated evidence of a monoclonal immunoglobulin heavy chain gene rearrangement, but no T-cell receptor gene rearrangement was found. In situ hybridization study for EBV-encoded RNA was positive. She was diagnosed with an EBV-associated IVTL. The patient's skin lesions were refractory to the combination of chemotherapy and autologous stem cell transplant, and she expired. The findings in the present case may highlight the unique clinicopathologic aspects of EBV-associated cytotoxic IVTL that occurred in a young, immunocompetent woman.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Jang YH,Lee SJ,Choi YH,Lee WJ,Kim DW,Kim J,Park TI,Chae YSdoi
10.5021/ad.2014.26.4.496subject
Has Abstractpub_date
2014-08-01 00:00:00pages
496-500issue
4eissn
1013-9087issn
2005-3894journal_volume
26pub_type
abstract：BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of r...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.5.600
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Malassezia yeasts are normal flora of the skin that are discovered in 75~98% of health subjects, but since its association with various skin disorders have been known, many studies have been conducted in the distribution of the yeasts. OBJECTIVE:To isolate, identify, and classify Malassezia yeasts from the ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.1.18
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:There is evidence that glycosaminoglycans (GAGs) are present in the hair shaft within the follicle but there are no studies regarding GAGs isolation and measurement in the human hair shaft over the scalp surface, it means, in the free hair shaft. OBJECTIVE:The purpose of our research was to isolate and meas...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.5.533
更新日期：2016-10-01 00:00:00
abstract：:Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2015.27.3.315
更新日期：2015-06-01 00:00:00
abstract：Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2018.30.2.143
更新日期：2018-04-01 00:00:00
abstract：:Hydroa vacciniforme (HV) is a photosensitivity disorder characterized by recurrent necrotic vesiculopapules on sun-exposed areas, which heal spontaneously during adolescence. Recently, an association has been reported between latent Epstein-Barr virus (EBV) infection and atypical HV-like eruption and malignant potenti...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2009.21.2.209
更新日期：2009-05-01 00:00:00
abstract：:Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogen...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2009.21.2.174
更新日期：2009-05-01 00:00:00
abstract：:Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S3.S290
更新日期：2011-12-01 00:00:00
abstract：:Epidermolysis bullosa (EB) is a rare hereditary disorder characterized by formation of blisters following minor trauma. It has been traditionally categorized by the level of basement membrane zone separation into EB simplex (EBS), junctional EB (JEB), and dystrophic EB (DEB). Recently, hemidesmosomal EB has been propo...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S1.S41
更新日期：2011-09-01 00:00:00
abstract：:This is the first case report to describe a 44-year-old woman with a history of advanced hepatocellular carcinoma who developed toxic epidermal necrolysis (TEN) clinically after taking 400 mg sorafenib (Nexavar®, BAY 43-9006) and tosufloxacin orally once per day. Both sorafenib and tosufloxacin were eventually discont...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S3.S404
更新日期：2011-12-01 00:00:00
abstract：:Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2017.29.6.782
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Several workers have found that Malassezia are capable of suppressing cytokine release and downregulating the phagocytic function of monocytes. But lipid-depleted Malassezia furfur (M. furfur) extracts have also been shown to induce increased production of TNF-alpha, IL-6 and IL-1beta in monocytes. We though...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.2.130
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND:The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role of growth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied and no controlled trials have been performed. OBJECTIVE:We evaluated the anti...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.5.584
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.3.261
更新日期：2009-08-01 00:00:00
abstract：:Blue nevi are characterized by a collection of pigment-producing melanocytes in the dermis. These lesions clinically present as well demarcated cerulean-blue or bluish black colored papules or plaques that usually measure less than 1 cm in diameter. They are typically found on the dorsal surface of the hands and feet ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.1.119
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:The expression of c-Met is substantially elevated in most malignant human cancers. We therefore searched for c-Met expression and compared the expression level among malignant skin cancers. OBJECTIVE:The aim of this study was to determine the c-Met expression pattern and the protein expression level in sele...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2011.23.1.33
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Hair follicles undergo cycles of repeated growth and regression. The Wnt pathway plays an important role in the regeneration and differentiation of hair follicles. Sfrp2, a Wnt inhibitor, is involved in the developmental and disease processes of various cells and tissues by modulating the Wnt pathway. OBJEC...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.1.79
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD). OBJECTIVE:The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution. METH...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.3.292
更新日期：2013-08-01 00:00:00
abstract：Background:Atopic dermatitis (AD) has increased in frequency to rates as high as 20% for children in developed countries. AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. Thus, a broad understanding of genetic background is needed for early diagnosi...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2018.30.3.276
更新日期：2018-06-01 00:00:00
abstract：:Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.3.405
更新日期：2011-08-01 00:00:00
abstract：:[This corrects the article on p. 217 in vol. 21.]. ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.3.335
更新日期：2009-08-01 00:00:00
abstract：:Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2018.30.4.468
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in recent years to find new ways of treating and preventing atopic derm...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2012.24.2.189
更新日期：2012-05-01 00:00:00
abstract：:Acute generalized exanthematous pustulosis (AGEP) is a cutaneous reaction principally induced by drugs. Spontaneous resolution is observed in most patients. However, severe cases required systemic corticosteroid administration. Hydroxychloroquine, which is used to treat some dermatologic and rheumatologic diseases bec...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2015.27.4.431
更新日期：2015-08-01 00:00:00
abstract：:[This corrects the article on p. 211 in vol. 30, PMID: 29606819.]. ...
journal_title：Annals of dermatology
pub_type： 已发布勘误
doi：10.5021/ad.2018.30.4.511
更新日期：2018-08-01 00:00:00
abstract：:Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp. ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.3.319
更新日期：2010-08-01 00:00:00
abstract：:Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.1.48
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2015.27.4.371
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Gray hair naturally develops in the process of human aging. Many people with gray hair periodically dye their hair. Hair dyeing products are widely used and they can cause adverse effects. Therefore, the user's knowledge and recognition about hair dyeing and related side effects are important. OBJECTIVE:The...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2012.24.3.274
更新日期：2012-08-01 00:00:00
abstract：:Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspect...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2013.25.3.352
更新日期：2013-08-01 00:00:00
