Expression of sfrp2 is increased in catagen of hair follicles and inhibits keratinocyte proliferation.

abstract：BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...

journal_title：Annals of dermatology

authors： Sul GD,Park HJ,Bae JH,Hong KD,Park BD,Chun J,Jeong SK,Lee SH,Ahn SK,Kim HJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...

journal_title：Annals of dermatology

authors： Park JM,Cho HH,Kim WJ,Mun JH,Song M,Kim HS,Ko HC,Kim BS,Kim MB

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Hair loss and hair growth is the subject of tremendous amount of research. OBJECTIVE:This study investigated the efficacy of three chemical treatments used in humans for hair loss, using a rat model of hair regrowth. The products tested were 2% minoxidil, Hairgrow (Dar-Al-Dawa Pharma), Aminexil, Dercos (Vic...

journal_title：Annals of dermatology

authors： Orasan MS,Bolfa P,Coneac A,Muresan A,Mihu C

更新日期：2016-02-01 00:00:00

abstract：:Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...

journal_title：Annals of dermatology

authors： Seo JW,Son HH,Choi JH,Lee SK

更新日期：2010-02-01 00:00:00

abstract：:A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granul...

journal_title：Annals of dermatology

authors： Chiba T,Takahara M,Nakahara T,Fukagawa S,Takei K,Shono A,Kiryu H,Moroi Y,Furue M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze...

journal_title：Annals of dermatology

authors： Roh NK,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2016-04-01 00:00:00

abstract：:The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy has not yet been reported. Herein, we report the first case of an erythrodermic ...

journal_title：Annals of dermatology

authors： Park SK,Hwang PH,Yun SK,Kim HU,Park J

更新日期：2017-02-01 00:00:00

abstract：:Disseminated superficial porokeratosis (DSP) is a rare variant of porokeratosis, which is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. DSP is usually associated with immunosuppressive states and hematopoietic malignancies, but rarely with malignancies of visc...

journal_title：Annals of dermatology

authors： Kim SW,Min SU,Won CH,Cho S

更新日期：2008-12-01 00:00:00

abstract：:We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm reve...

journal_title：Annals of dermatology

authors： Na SY,Son YM,Lee HY,Baek JO,Roh JY,Lee JR

更新日期：2009-02-01 00:00:00

abstract：Background:Alopecia areata (AA) affects anagen hair follicles resulting in non-scarring hair loss. Since its introduction, superficial cryotherapy has been used as one of the meaningful treatment modalities for AA. Objective:The purpose of this study is to clarify the therapeutic efficacy and safety of superficial cry...

journal_title：Annals of dermatology

authors： Jun M,Lee WS

更新日期：2017-12-01 00:00:00

abstract：:Lichen aureus is a rare type of chronic pigmented purpuric dermatosis. The eruptions consist of discrete or confluent golden to brownish lichenoid macules and papules, and are usually asymptomatic. Lichen aureus commonly occurs in young adults, but less frequently in children. We report the first case of multiple lich...

journal_title：Annals of dermatology

authors： Kim MJ,Kim BY,Park KC,Youn SW

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PAS...

journal_title：Annals of dermatology

authors： Youn SW,Choi CW,Kim BR,Chae JB

更新日期：2015-10-01 00:00:00

abstract：:Actinomycotic infections are known to have an association with difficulties in diagnosis and treatment. These infections usually involve the head, neck, thorax, and abdomen. Actinomycosis of the upper lip is a rare condition and an important one as well, because it can imitate other diseases. As the initial impression...

journal_title：Annals of dermatology

authors： Lee YS,Sim HS,Lee SK

更新日期：2011-09-01 00:00:00

abstract：:Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-ass...

journal_title：Annals of dermatology

authors： Lim JS,Kim TM,Cho KH

更新日期：2017-10-01 00:00:00

abstract：:We report on a rare case of fluconazole induced fixed drug eruption in a 62-year old female patient. She was referred to our department for multiple erythematous itchy maculopatches on the face, neck, both upper arms, and trunk area, which had occurred over the previous 6 months. Her attending physician prescribed flu...

journal_title：Annals of dermatology

authors： Kim CY,Kim JG,Oh CW

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) should be relatively well informed about the disorder to control their condition and prevent flare-ups. Thus far, there is no accurate information about the disease awareness levels and therapeutic behavior of AD patients. OBJECTIVE:To collect data on patients' knowledge...

journal_title：Annals of dermatology

authors： Kim JE,Lee YB,Lee JH,Kim HS,Lee KH,Park YM,Cho SH,Lee JY

更新日期：2015-02-01 00:00:00

abstract：:Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, ...

journal_title：Annals of dermatology

authors： Kim JS,Choi M,Nam CH,Kim JY,Park BC,Kim MH,Hong SP

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Chemokines and their receptors are important players in tumorigenesis by facilitating tumor proliferation and metastasis. Little is known about the possible function of chemokine receptors in relation to the development and progression of malignant cutaneous tumors. OBJECTIVE:The aim of this study was to de...

journal_title：Annals of dermatology

authors： Lee YJ,Kim DH,Lee SH,Nam HS,Roh MR,Cho MK

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The clinical symptoms of facial and truncal acne differ. Skin surface acidity (pH), which is affected by sebum secretions, reflects the different clinical characteristics of the face and trunk. However, no studies have been conducted on truncal sebum production and skin pH. OBJECTIVE:We evaluated the differ...

journal_title：Annals of dermatology

authors： Kim SA,Kim BR,Chun MY,Youn SW

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE:The aim of this study was to investigate the effect of retinoid on the expression of corneodesmosomal components ...

journal_title：Annals of dermatology

authors： Kim MY,Lee SE,Chang JY,Kim SC

更新日期：2011-11-01 00:00:00

abstract：:Sweet's syndrome is a reactive dermatosis characterized clinically by fever, leukocytosis, and multiple, erythematous, painful plaques. Histopathologic examination reveals a band-like dense dermal inflammatory infiltrate composed mainly of neutrophils with papillary dermal edema, and no features of vasculitis. We repo...

journal_title：Annals of dermatology

authors： Lee GY,Do MO,Kim SH,Choi HY,Myung KB,Choi YW

更新日期：2009-08-01 00:00:00

abstract：:Although more than 90% of melanomas have cutaneous origins, melanomas sometimes present metastatically with no apparent primary lesion. A 62-year-old female presented with black pigmentation on her left thumbnail that had begun 2 years earlier and after the biopsy, she was diagnosed with malignant melanoma. Interestin...

journal_title：Annals of dermatology

authors： Lee S,Lee HJ,Oh SH,Im M,Lee JH,Seo YJ,Lee Y

更新日期：2011-10-01 00:00:00

abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...

journal_title：Annals of dermatology

authors： Choi MJ,Kim HS,Kim HO,Song KY,Park YM

更新日期：2010-05-01 00:00:00

abstract：:Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower b...

journal_title：Annals of dermatology

authors： Lee WJ,Park GH,Chang SE,Lee MW,Choi JH,Moon KC,Koh JK

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of r...

journal_title：Annals of dermatology

authors： Shin H,Choi SJ,Cho AR,Kim DY,Kim KH,Kwon O

更新日期：2016-10-01 00:00:00

abstract：:Epidermolysis bullosa (EB) is a rare hereditary disorder characterized by formation of blisters following minor trauma. It has been traditionally categorized by the level of basement membrane zone separation into EB simplex (EBS), junctional EB (JEB), and dystrophic EB (DEB). Recently, hemidesmosomal EB has been propo...

journal_title：Annals of dermatology

authors： Kim JH,Park HY,Lee HJ,Eom M,Choi EH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...

journal_title：Annals of dermatology

authors： Kim JH,Choi DK,Lee SS,Choi SJ,Kim CD,Yoon TJ,Lee JH

更新日期：2010-08-01 00:00:00

abstract：:Leiomyosarcomas are uncommon malignant smooth muscle tumors, mainly derived from vessels or viscera. Superficial leiomyosarcomas are a rare soft tissue sarcoma arising from the dermis or subcutaneous tissue in the skin. According to tumor origin and location, they are divided into cutaneous and subcutaneous leiomyosar...

journal_title：Annals of dermatology

authors： Lee KC,Kim MS,Choi H,Na CH,Shin BS

更新日期：2013-05-01 00:00:00

abstract：:Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspect...

journal_title：Annals of dermatology

authors： Kumar S,Sidhu S,Mahajan BB

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Gray hair naturally develops in the process of human aging. Many people with gray hair periodically dye their hair. Hair dyeing products are widely used and they can cause adverse effects. Therefore, the user's knowledge and recognition about hair dyeing and related side effects are important. OBJECTIVE:The...

journal_title：Annals of dermatology

authors： Kim JE,Jung HD,Kang H

更新日期：2012-08-01 00:00:00