Expression of sfrp2 is increased in catagen of hair follicles and inhibits keratinocyte proliferation.

abstract：BACKGROUND:Chemokines and their receptors are important players in tumorigenesis by facilitating tumor proliferation and metastasis. Little is known about the possible function of chemokine receptors in relation to the development and progression of malignant cutaneous tumors. OBJECTIVE:The aim of this study was to de...

journal_title：Annals of dermatology

authors： Lee YJ,Kim DH,Lee SH,Nam HS,Roh MR,Cho MK

更新日期：2010-11-01 00:00:00

abstract：:A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...

journal_title：Annals of dermatology

authors： Hwang SW,Cho KJ,Oh DJ,Lee D,Kim JW,Park SW

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...

journal_title：Annals of dermatology

authors： Sul GD,Park HJ,Bae JH,Hong KD,Park BD,Chun J,Jeong SK,Lee SH,Ahn SK,Kim HJ

更新日期：2013-02-01 00:00:00

abstract：:Epidermolysis bullosa (EB) is a rare hereditary disorder characterized by formation of blisters following minor trauma. It has been traditionally categorized by the level of basement membrane zone separation into EB simplex (EBS), junctional EB (JEB), and dystrophic EB (DEB). Recently, hemidesmosomal EB has been propo...

journal_title：Annals of dermatology

authors： Kim JH,Park HY,Lee HJ,Eom M,Choi EH

更新日期：2011-09-01 00:00:00

abstract：Background:Atopic dermatitis (AD) has increased in frequency to rates as high as 20% for children in developed countries. AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. Thus, a broad understanding of genetic background is needed for early diagnosi...

journal_title：Annals of dermatology

authors： Heo WI,Park KY,Lee MK,Kim JH,Moon NJ,Seo SJ

更新日期：2018-06-01 00:00:00

abstract：:We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm reve...

journal_title：Annals of dermatology

authors： Na SY,Son YM,Lee HY,Baek JO,Roh JY,Lee JR

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Although intralesional methotrexate (MTX) is an effective, nonsurgical treatment of keratoacanthoma (KA), there have not been many reports of on the MTX treatment for KA in Korea. OBJECTIVE:The purpose of this study was to evaluate the clinical efficacy of the intralesional MTX for the treatment of KA in Ko...

journal_title：Annals of dermatology

authors： Yoo MG,Kim IH

更新日期：2014-04-01 00:00:00

abstract：:An atypical clinical form of pityriasis versicolor has been infrequently reported, in which cutaneous atrophy is associated with individual pityriasis versicolor lesions. The pathogenesis of this atrophy remains unclear, but is believed to be a delayed-type hypersensitivity reaction to antigens derived from the Malass...

journal_title：Annals of dermatology

authors： Yang YS,Shin MK,Haw CR

更新日期：2010-11-01 00:00:00

abstract：:Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower b...

journal_title：Annals of dermatology

authors： Lee WJ,Park GH,Chang SE,Lee MW,Choi JH,Moon KC,Koh JK

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Short stature is sometimes seen in children with atopic dermatitis (AD); however, the topic has never been studied systematically. OBJECTIVE:The aim of this study was to show whether AD itself affects stature in children and to evaluate the influence of other relevant factors such as genetic background, die...

journal_title：Annals of dermatology

authors： Park MK,Park KY,Li K,Seo SJ,Hong CK

更新日期：2013-02-01 00:00:00

abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...

journal_title：Annals of dermatology

authors： Choi MJ,Kim HS,Kim HO,Song KY,Park YM

更新日期：2010-05-01 00:00:00

abstract：:Fexofenadine (Allegra® 180) is a second-generation antihistamine. It is widely used as anti-allergic drug, which suppresses various allergic reactions mediated by histamines. A few cases of H1-antihistamine-induced urticaria have been reported. Herein, we report a rare case of fexofenadine-induced urticaria which was ...

journal_title：Annals of dermatology

authors： Lee SW,Byun JY,Choi YW,Myung KB,Choi HY

更新日期：2011-12-01 00:00:00

abstract：:Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogen...

journal_title：Annals of dermatology

authors： Lee Y,Ahn SY,Ji JH,Hong SP,Bak H,Lee SH,Ahn SK

更新日期：2009-05-01 00:00:00

abstract：:Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walki...

journal_title：Annals of dermatology

authors： Chung J,Namkoong S,Sim JH,Lee JS,Hong SP,Kim MH,Park BC

更新日期：2011-10-01 00:00:00

abstract：:Pityriasis versicolor is a superficial infection of the stratum corneum, which is caused by the Malassezia species. Tge Malassezia species consist of 12 subspecies, including M. furfur, M. pachydermatis, M. symphodialis and M. globasa. The Malassezia species are classified as a normal flora, particularly in the sebum ...

journal_title：Annals of dermatology

authors： Ryu HW,Cho JW,Lee KS

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Low fluence 1,064 nm Q-switched (QS) Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment, also known as laser toning, is widely used for pigmentary disorders. There has been no reliable evaluation of the effect of low fluence 1,064 nm QS Nd:YAG laser for senile lentigo. OBJECTIVE:To investigate the b...

journal_title：Annals of dermatology

authors： Nam JH,Kim HS,Lee GY,Kim WS

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) should be relatively well informed about the disorder to control their condition and prevent flare-ups. Thus far, there is no accurate information about the disease awareness levels and therapeutic behavior of AD patients. OBJECTIVE:To collect data on patients' knowledge...

journal_title：Annals of dermatology

authors： Kim JE,Lee YB,Lee JH,Kim HS,Lee KH,Park YM,Cho SH,Lee JY

更新日期：2015-02-01 00:00:00

abstract：:Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenita...

journal_title：Annals of dermatology

authors： Lee HJ,Shin DH,Choi JS,Kim KH

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE:To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD...

journal_title：Annals of dermatology

authors： Lim SK,Lim CA,Kwon IS,Im M,Seo YJ,Kim CD,Lee JH,Lee Y

更新日期：2017-06-01 00:00:00

abstract：:Nicolau syndrome is a rare adverse reaction to a variety of intra-muscular drug preparations. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, hemorrhagic patch, and finally, necrosis of skin, subcutaneous fat, and muscle tissue. The phenomenon has ...

journal_title：Annals of dermatology

authors： Kim KK

更新日期：2011-11-01 00:00:00

abstract：:Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...

journal_title：Annals of dermatology

authors： Lee D,Kang JH,Kim SH,Seo JK,Sung HS,Hwang SW

更新日期：2008-09-01 00:00:00

abstract：:Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...

journal_title：Annals of dermatology

authors： Lee SH,Kim YS,Kim HJ,Park YL

更新日期：2017-12-01 00:00:00

abstract：:Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on ...

journal_title：Annals of dermatology

authors： Lim JY,Do MO,Kim SH,Hahm JH,Whang KK

更新日期：2008-12-01 00:00:00

abstract：Background:Alopecia areata (AA) affects anagen hair follicles resulting in non-scarring hair loss. Since its introduction, superficial cryotherapy has been used as one of the meaningful treatment modalities for AA. Objective:The purpose of this study is to clarify the therapeutic efficacy and safety of superficial cry...

journal_title：Annals of dermatology

authors： Jun M,Lee WS

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...

journal_title：Annals of dermatology

authors： Kim JH,Choi DK,Lee SS,Choi SJ,Kim CD,Yoon TJ,Lee JH

更新日期：2010-08-01 00:00:00

abstract：:We report on a rare case of fluconazole induced fixed drug eruption in a 62-year old female patient. She was referred to our department for multiple erythematous itchy maculopatches on the face, neck, both upper arms, and trunk area, which had occurred over the previous 6 months. Her attending physician prescribed flu...

journal_title：Annals of dermatology

authors： Kim CY,Kim JG,Oh CW

更新日期：2011-09-01 00:00:00

abstract：:A 50-year-old man and 71-year-old woman presented to our clinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical and histopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planu...

journal_title：Annals of dermatology

authors： Yayla D,Külcü Çakmak S,Oğuz ID,Gönül M,Ozhamam E,Colak A,Gül U

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE:The objective of this study is to characteriz...

journal_title：Annals of dermatology

authors： Kim JM,Lim KM,Kim HS,Ko HC,Kim MB,Kim BS

更新日期：2017-04-01 00:00:00

abstract：:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...

journal_title：Annals of dermatology

authors： Yoon SY,Kwon HH,Jeon HC,Lee JH,Cho S

更新日期：2011-11-01 00:00:00

abstract：:Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless...

journal_title：Annals of dermatology

authors： Paek JO,Kang HS,Yeo KY,Yu HJ,Kim JS

更新日期：2011-05-01 00:00:00