Abstract：
BACKGROUND:Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE:The objective of this study is to characterize the clinical patterns of pruritus in patients with urticarial dermatitis and to determine the effectiveness of cyclosporine treatment. METHODS:This prospective study included 50 histopathologically confirmed patients with urticarial dermatitis. A face-to-face structured questionnaire was given to all patients, and they were treated with low-dose cyclosporine (1~3 mg/kg/d) for at least 2 weeks. RESULTS:The majority of patients (80.0%) had moderate to severe pruritus. Most patients experienced exacerbation of the itch in the evening (74.0%), with the extremities (upper, 86.0%; lower, 94.0%) being the most commonly involved sites. Due to severe pruritus, patients complained about reduced social contact, quality of life and difficulties in falling asleep et al. Cyclosporine significantly reduced the mean itch score and extent of erythema, and improved interference with daily activities and sleep. CONCLUSION:Our study highlights the detailed description and characteristics of pruritus in patients with urticarial dermatitis. And we recommend alternative and effective therapeutic option of low-dose cyclosporine.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Kim JM,Lim KM,Kim HS,Ko HC,Kim MB,Kim BSdoi
10.5021/ad.2017.29.2.143subject
Has Abstractpub_date
2017-04-01 00:00:00pages
143-148issue
2eissn
1013-9087issn
2005-3894journal_volume
29pub_type
杂志文章abstract：:Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages ...
journal_title：Annals of dermatology
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doi：10.5021/ad.2008.20.2.98
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abstract：:Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless...
journal_title：Annals of dermatology
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doi：10.5021/ad.2011.23.2.201
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journal_title：Annals of dermatology
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doi：10.5021/ad.2017.29.4.487
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abstract：BACKGROUND:VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE:In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis. METHODS:Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic der...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2017.29.5.548
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abstract：BACKGROUND:Malassezia yeasts are normal flora of the skin that are discovered in 75~98% of health subjects, but since its association with various skin disorders have been known, many studies have been conducted in the distribution of the yeasts. OBJECTIVE:To isolate, identify, and classify Malassezia yeasts from the ...
journal_title：Annals of dermatology
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abstract：:Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-ass...
journal_title：Annals of dermatology
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doi：10.5021/ad.2017.29.5.618
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abstract：:Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...
journal_title：Annals of dermatology
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doi：10.5021/ad.2017.29.6.782
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abstract：:Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...
journal_title：Annals of dermatology
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doi：10.5021/ad.2018.30.4.468
更新日期：2018-08-01 00:00:00
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journal_title：Annals of dermatology
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doi：10.5021/ad.2011.23.S3.S404
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journal_title：Annals of dermatology
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doi：10.5021/ad.2009.21.3.300
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2013.25.3.352
更新日期：2013-08-01 00:00:00
abstract：:Intravascular lymphoma (IVL) is a rare disorder characterized by the presence of large neoplastic lymphoid cells restricted to the lumens of small vessels with a predilection for the skin and the central nervous system. While the vast majority of cases involving IVL are of B-cell lineage, the disease rarely affects th...
journal_title：Annals of dermatology
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doi：10.5021/ad.2014.26.4.496
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abstract：:Eosinophic fasciitis (EF) is an uncommon connective tissue disease characterized by scleroderma-like cutaneous changes, peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate (ESR). Typical histopathologic findings include chronic inflammatory infiltration affecting the deep fa...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.1.81
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abstract：BACKGROUND:Chronic idiopathic urticaria (CIU) is considered a complex and multifactorial disease. Excessive histamine intake may induce an attack of urticaria. The main enzyme for histamine metabolism is diamine oxidase (DAO). OBJECTIVE:Plasma histamine concentrations and DAO activities were evaluated to determine whe...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.2.189
更新日期：2013-05-01 00:00:00
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journal_title：Annals of dermatology
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doi：10.5021/ad.2010.22.1.48
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S2.S160
更新日期：2011-10-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.1.119
更新日期：2010-02-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.3.319
更新日期：2010-08-01 00:00:00
abstract：:Lichen aureus is a rare type of chronic pigmented purpuric dermatosis. The eruptions consist of discrete or confluent golden to brownish lichenoid macules and papules, and are usually asymptomatic. Lichen aureus commonly occurs in young adults, but less frequently in children. We report the first case of multiple lich...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2009.21.4.393
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abstract：BACKGROUND:Several workers have found that Malassezia are capable of suppressing cytokine release and downregulating the phagocytic function of monocytes. But lipid-depleted Malassezia furfur (M. furfur) extracts have also been shown to induce increased production of TNF-alpha, IL-6 and IL-1beta in monocytes. We though...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.2.130
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journal_title：Annals of dermatology
pub_type： 杂志文章
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journal_title：Annals of dermatology
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doi：10.5021/ad.2008.20.4.193
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journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.4.434
更新日期：2013-11-01 00:00:00
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journal_title：Annals of dermatology
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doi：10.5021/ad.2009.21.2.209
更新日期：2009-05-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2008.20.4.233
更新日期：2008-12-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.3.358
更新日期：2010-08-01 00:00:00
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journal_title：Annals of dermatology
pub_type： 杂志文章
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journal_title：Annals of dermatology
pub_type： 杂志文章
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更新日期：2015-04-01 00:00:00
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journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.3.321
更新日期：2016-06-01 00:00:00
abstract：:Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2008.20.3.146
更新日期：2008-09-01 00:00:00
