Nicolau syndrome in patient following diclofenac administration: a case report.

Abstract:

:Nicolau syndrome is a rare adverse reaction to a variety of intra-muscular drug preparations. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, hemorrhagic patch, and finally, necrosis of skin, subcutaneous fat, and muscle tissue. The phenomenon has been related to the administration of a variety of drugs, including non-steroidal anti-inflammatory drugs, corticosteroids, and penicillin. We report a case with typical features associated with diclofenac injection for pain control in a patient who had undergone bilateral total knee arthroplasty.

journal_name

Ann Dermatol

journal_title

Annals of dermatology

authors

Kim KK

doi

10.5021/ad.2011.23.4.501

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

501-3

issue

4

eissn

1013-9087

issn

2005-3894

journal_volume

23

pub_type

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