Toxic epidermal necrolysis associated with sorafenib and tosufloxacin in a patient with hepatocellular carcinoma.

abstract：BACKGROUND:Multiplex polymerase chain reaction (PCR) allows more than two target DNA molecules to be amplified with more than two primers. This method is also useful for detecting various other organisms simultaneously within a single test tube, and the scope of its use has been expanding widely in the field of clinica...

journal_title：Annals of dermatology

authors： Kim JY,Choe YB,Ahn KJ,Lee YW

更新日期：2011-08-01 00:00:00

abstract：:Extraskeletal osteosarcoma (ESOS) is a very rare malignant tumor of mesenchymal origin. It is rarer than osseous osteosarcoma and there are very few reports of the skin being a primary site. Most reported cutaneous ESOS were accompanied with metastasis in other organs. A 56-year-old man presented with a painful, 1.5×0...

journal_title：Annals of dermatology

authors： Park SG,Song JY,Song IG,Kim MS,Shin BS

更新日期：2011-10-01 00:00:00

abstract：:Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...

journal_title：Annals of dermatology

authors： Lee D,Kang JH,Kim SH,Seo JK,Sung HS,Hwang SW

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of r...

journal_title：Annals of dermatology

authors： Shin H,Choi SJ,Cho AR,Kim DY,Kim KH,Kwon O

更新日期：2016-10-01 00:00:00

abstract：:Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-...

journal_title：Annals of dermatology

authors： Lee EA,Kim HS,Kim HO,Park YM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE:In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis. METHODS:Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic der...

journal_title：Annals of dermatology

authors： Lee JH,Jeon YJ,Choi JH,Kim HY,Kim TY

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Angiogenesis is crucial for wound healing and exogenous supplements of the angiogenic growth factors have been known to promote cutaneous wound healing. Angiopoietin (Ang) 1 is a recently discovered angiogenic factor and there have been few studies of its effect on cutaneous wound healing. OBJECTIVE:We exam...

journal_title：Annals of dermatology

authors： Kim YY,Kim YJ,Ku JK,Kim MY,Kim YI,Koh GY,Kim HO,Park YM

更新日期：2008-06-01 00:00:00

abstract：:Acquired brachial cutaneous dyschromatosis (ABCD) is an acquired disorder of pigmentary change that presents as chronic, asymptomatic, geographic-shaped, gray-brown patches, consisting of mixed hyper and hypopigmented macules on the dorsal aspect of the forearms. We report a case of a 40-year-old male who presented wi...

journal_title：Annals of dermatology

authors： Choi MJ,Byun JY,Choi HY,Choi YW

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Although intralesional methotrexate (MTX) is an effective, nonsurgical treatment of keratoacanthoma (KA), there have not been many reports of on the MTX treatment for KA in Korea. OBJECTIVE:The purpose of this study was to evaluate the clinical efficacy of the intralesional MTX for the treatment of KA in Ko...

journal_title：Annals of dermatology

authors： Yoo MG,Kim IH

更新日期：2014-04-01 00:00:00

abstract：:Sweet's syndrome is a reactive dermatosis characterized clinically by fever, leukocytosis, and multiple, erythematous, painful plaques. Histopathologic examination reveals a band-like dense dermal inflammatory infiltrate composed mainly of neutrophils with papillary dermal edema, and no features of vasculitis. We repo...

journal_title：Annals of dermatology

authors： Lee GY,Do MO,Kim SH,Choi HY,Myung KB,Choi YW

更新日期：2009-08-01 00:00:00

abstract：:Intravascular lymphoma (IVL) is a rare disorder characterized by the presence of large neoplastic lymphoid cells restricted to the lumens of small vessels with a predilection for the skin and the central nervous system. While the vast majority of cases involving IVL are of B-cell lineage, the disease rarely affects th...

journal_title：Annals of dermatology

authors： Jang YH,Lee SJ,Choi YH,Lee WJ,Kim DW,Kim J,Park TI,Chae YS

更新日期：2014-08-01 00:00:00

abstract：:Acute generalized exanthematous pustulosis (AGEP) is a cutaneous reaction principally induced by drugs. Spontaneous resolution is observed in most patients. However, severe cases required systemic corticosteroid administration. Hydroxychloroquine, which is used to treat some dermatologic and rheumatologic diseases bec...

journal_title：Annals of dermatology

authors： Yalçın B,Çakmak S,Yıldırım B

更新日期：2015-08-01 00:00:00

abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...

journal_title：Annals of dermatology

authors： Choi MJ,Kim HS,Kim HO,Song KY,Park YM

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...

journal_title：Annals of dermatology

authors： Park JM,Cho HH,Kim WJ,Mun JH,Song M,Kim HS,Ko HC,Kim BS,Kim MB

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Short stature is sometimes seen in children with atopic dermatitis (AD); however, the topic has never been studied systematically. OBJECTIVE:The aim of this study was to show whether AD itself affects stature in children and to evaluate the influence of other relevant factors such as genetic background, die...

journal_title：Annals of dermatology

authors： Park MK,Park KY,Li K,Seo SJ,Hong CK

更新日期：2013-02-01 00:00:00

abstract：:Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy. The nipple-areola complex (NAC) is an uncommon site for BCC to develop. BCCs in this region display more aggressive behavior and a greater potential to spread than when found i...

journal_title：Annals of dermatology

authors： Jung HJ,Jun JH,Kim HY,Lee SJ,Kim DW,Lee WJ,Jung JH

更新日期：2011-10-01 00:00:00

abstract：:Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp. ...

journal_title：Annals of dermatology

authors： Kim MS,Lee JH,Lee WM,Son SJ

更新日期：2010-08-01 00:00:00

abstract：:Fexofenadine (Allegra® 180) is a second-generation antihistamine. It is widely used as anti-allergic drug, which suppresses various allergic reactions mediated by histamines. A few cases of H1-antihistamine-induced urticaria have been reported. Herein, we report a rare case of fexofenadine-induced urticaria which was ...

journal_title：Annals of dermatology

authors： Lee SW,Byun JY,Choi YW,Myung KB,Choi HY

更新日期：2011-12-01 00:00:00

abstract：:Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on ...

journal_title：Annals of dermatology

authors： Lim JY,Do MO,Kim SH,Hahm JH,Whang KK

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PAS...

journal_title：Annals of dermatology

authors： Youn SW,Choi CW,Kim BR,Chae JB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE:To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD...

journal_title：Annals of dermatology

authors： Lim SK,Lim CA,Kwon IS,Im M,Seo YJ,Kim CD,Lee JH,Lee Y

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...

journal_title：Annals of dermatology

authors： Sul GD,Park HJ,Bae JH,Hong KD,Park BD,Chun J,Jeong SK,Lee SH,Ahn SK,Kim HJ

更新日期：2013-02-01 00:00:00

abstract：Background:Atopic dermatitis (AD) is related to a deficiency of delta-6-desaturase, an enzyme responsible for converting linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) as a source of GLA has been of interest in the management of AD. Objective:The aim of this randomized, double-blinded, placebo...

journal_title：Annals of dermatology

authors： Chung BY,Park SY,Jung MJ,Kim HO,Park CW

更新日期：2018-08-01 00:00:00

abstract：:Blastomycosis-like pyoderma is a rare, vegetating skin lesion that is an unusual exaggerated tissue reaction possibly to prolonged primary or secondary bacterial infection. We report a case of blastomycosis-like pyoderma in a man with Down syndrome, diabetes mellitus and hypothyroidism who responsed poorly to conventi...

journal_title：Annals of dermatology

authors： Lee YS,Jung SW,Sim HS,Seo JK,Lee SK

更新日期：2011-08-01 00:00:00

abstract：:Disseminated superficial porokeratosis (DSP) is a rare variant of porokeratosis, which is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. DSP is usually associated with immunosuppressive states and hematopoietic malignancies, but rarely with malignancies of visc...

journal_title：Annals of dermatology

authors： Kim SW,Min SU,Won CH,Cho S

更新日期：2008-12-01 00:00:00

abstract：:A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...

journal_title：Annals of dermatology

authors： Hwang SW,Cho KJ,Oh DJ,Lee D,Kim JW,Park SW

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...

journal_title：Annals of dermatology

authors： Hwang SW,Hong SK,Kim SH,Park JH,Seo JK,Sung HS,Lee D

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...

journal_title：Annals of dermatology

authors： Jin MH,Park SG,Hwang YL,Lee MH,Jeong NJ,Roh SS,Lee Y,Kim CD,Lee JH

更新日期：2012-02-01 00:00:00

abstract：:Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...

journal_title：Annals of dermatology

authors： Kim GW,Park HJ,Kim HS,Kim SH,Ko HC,Kim BS,Kim MB

更新日期：2011-12-01 00:00:00

abstract：:Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...

journal_title：Annals of dermatology

authors： Ohn J,Bae JM,Lim JS,Park JS,Yoon HS,Cho S,Park HS

更新日期：2017-06-01 00:00:00