A case of focal acral hyperkeratosis.

Abstract:

:Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-year-old male with a family history of similar lesions in three generations. The histological findings revealed focal areas of orthohyperkeratosis over an area of depressed but otherwise normal epidermis. The dermis showed no specific changes, which distinguished this case from acrokeratoelastoidosis, which shows elastorrhexis of clinically similar lesions.

journal_name

Ann Dermatol

journal_title

Annals of dermatology

authors

Lee EA,Kim HS,Kim HO,Park YM

doi

10.5021/ad.2009.21.4.426

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

426-8

issue

4

eissn

1013-9087

issn

2005-3894

journal_volume

21

pub_type

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