Abstract:
:Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-year-old male with a family history of similar lesions in three generations. The histological findings revealed focal areas of orthohyperkeratosis over an area of depressed but otherwise normal epidermis. The dermis showed no specific changes, which distinguished this case from acrokeratoelastoidosis, which shows elastorrhexis of clinically similar lesions.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Lee EA,Kim HS,Kim HO,Park YMdoi
10.5021/ad.2009.21.4.426subject
Has Abstractpub_date
2009-11-01 00:00:00pages
426-8issue
4eissn
1013-9087issn
2005-3894journal_volume
21pub_type
abstract::Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2017.29.3.327
更新日期:2017-06-01 00:00:00
abstract::Hematodermic neoplasm (HN) is a clinically aggressive neoplasm with a high incidence of cutaneous involvement and a risk of leukemic dissemination. In the recent WHO-EORTC classification, the term blastic natural killer cell lymphoma has been replaced with CD4+/CD56+ HN because of its derivation from a plasmacytoid de...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.2.186
更新日期:2010-05-01 00:00:00
abstract::A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.1.11
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE:In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis. METHODS:Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic der...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.5.548
更新日期:2017-10-01 00:00:00
abstract::This is the first case report to describe a 44-year-old woman with a history of advanced hepatocellular carcinoma who developed toxic epidermal necrolysis (TEN) clinically after taking 400 mg sorafenib (Nexavar®, BAY 43-9006) and tosufloxacin orally once per day. Both sorafenib and tosufloxacin were eventually discont...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S3.S404
更新日期:2011-12-01 00:00:00
abstract:Background:Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival. Objective:We sought to establish screening strategy for SUM in situ. Methods:We retrospectively reviewed medical records of 8 patients pathologically diagno...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.1.36
更新日期:2018-02-01 00:00:00
abstract::Actinomycotic infections are known to have an association with difficulties in diagnosis and treatment. These infections usually involve the head, neck, thorax, and abdomen. Actinomycosis of the upper lip is a rare condition and an important one as well, because it can imitate other diseases. As the initial impression...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S1.S131
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.3.261
更新日期:2009-08-01 00:00:00
abstract::Extraskeletal osteosarcoma (ESOS) is a very rare malignant tumor of mesenchymal origin. It is rarer than osseous osteosarcoma and there are very few reports of the skin being a primary site. Most reported cutaneous ESOS were accompanied with metastasis in other organs. A 56-year-old man presented with a painful, 1.5×0...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S160
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.4.431
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Recently, the pulse-in-pulse mode of intense pulsed light (IPL) has been used increasingly for the treatment of melasma. OBJECTIVE:To observe the morphologic changes in the melanophore in adult zebrafish after irradiation with conventional and pulse-in-pulse IPL and Q-switched Nd:YAG (QSNY) laser. METHODS:...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.6.711
更新日期:2016-12-01 00:00:00
abstract::Eosinophic fasciitis (EF) is an uncommon connective tissue disease characterized by scleroderma-like cutaneous changes, peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate (ESR). Typical histopathologic findings include chronic inflammatory infiltration affecting the deep fa...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.1.81
更新日期:2011-02-01 00:00:00
abstract::Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.4.539
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.4.371
更新日期:2015-08-01 00:00:00
abstract::We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm reve...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.1.98
更新日期:2009-02-01 00:00:00
abstract::Vitiligo is an acquired depigmentary disorder of the skin that results from the loss of functioning epidermal melanocytes. Most studies on vitiligo have concentrated on the abnormality of melanocytes rather than the abnormality of keratinocytes; however, epidermal melanocytes form a functional and structural unit with...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.2.115
更新日期:2012-05-01 00:00:00
abstract::[This corrects the article on p. 217 in vol. 21.]. ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.3.335
更新日期:2009-08-01 00:00:00
abstract::Telogen effluvium is categorized in nonscarring alopecia, which shows scalp hair thinning and shedding diffusely resulting from inducing factors such as physiological stressful events and several acute or chronic diseases. It usually appears in female patients following parturition, as well as after febrile disease, m...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2018.30.2.214
更新日期:2018-04-01 00:00:00
abstract:Background:Atopic dermatitis (AD) is related to a deficiency of delta-6-desaturase, an enzyme responsible for converting linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) as a source of GLA has been of interest in the management of AD. Objective:The aim of this randomized, double-blinded, placebo...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.4.409
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Chronic idiopathic urticaria (CIU) is considered a complex and multifactorial disease. Excessive histamine intake may induce an attack of urticaria. The main enzyme for histamine metabolism is diamine oxidase (DAO). OBJECTIVE:Plasma histamine concentrations and DAO activities were evaluated to determine whe...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.2.189
更新日期:2013-05-01 00:00:00
abstract::Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2018.30.4.468
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Patients with atopic dermatitis (AD) should be relatively well informed about the disorder to control their condition and prevent flare-ups. Thus far, there is no accurate information about the disease awareness levels and therapeutic behavior of AD patients. OBJECTIVE:To collect data on patients' knowledge...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.1.40
更新日期:2015-02-01 00:00:00
abstract::Epidermolysis bullosa (EB) is a rare hereditary disorder characterized by formation of blisters following minor trauma. It has been traditionally categorized by the level of basement membrane zone separation into EB simplex (EBS), junctional EB (JEB), and dystrophic EB (DEB). Recently, hemidesmosomal EB has been propo...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S1.S41
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Gray hair naturally develops in the process of human aging. Many people with gray hair periodically dye their hair. Hair dyeing products are widely used and they can cause adverse effects. Therefore, the user's knowledge and recognition about hair dyeing and related side effects are important. OBJECTIVE:The...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.3.274
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.1.16
更新日期:2012-02-01 00:00:00
abstract::Pityriasis versicolor is a superficial infection of the stratum corneum, which is caused by the Malassezia species. Tge Malassezia species consist of 12 subspecies, including M. furfur, M. pachydermatis, M. symphodialis and M. globasa. The Malassezia species are classified as a normal flora, particularly in the sebum ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2012.24.3.345
更新日期:2012-08-01 00:00:00
abstract:Background:Atopic dermatitis (AD) has increased in frequency to rates as high as 20% for children in developed countries. AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. Thus, a broad understanding of genetic background is needed for early diagnosi...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.3.276
更新日期:2018-06-01 00:00:00
abstract:Background:Alopecia areata (AA) affects anagen hair follicles resulting in non-scarring hair loss. Since its introduction, superficial cryotherapy has been used as one of the meaningful treatment modalities for AA. Objective:The purpose of this study is to clarify the therapeutic efficacy and safety of superficial cry...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.6.722
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD). OBJECTIVE:The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution. METH...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.3.292
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of r...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.5.600
更新日期:2016-10-01 00:00:00