Reduction of Inter-Rater and Intra-Rater Variability in Psoriasis Area and Severity Index Assessment by Photographic Training.


BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PASI assessment. OBJECTIVE:In the present study, we aimed to investigate whether photographic training improves inter-rater and intra-rater variabilities. We also determined which PASI component has the greatest impact on variability. METHODS:Twenty-one dermatologists received 1 hour of PASI training. They were tested before and after the training to evaluate intra-rater variability. The physicians were further tested after training by using a reference photograph. RESULTS:The mean of each PASI component was underevaluated compared with scoring by a PASI expert. The concordance rate with the expert's grading was highest for thickness followed by erythema, scaling, and area. The scaling score showed the greatest improvement after training. After training, the distribution of deviation from the expert's grading, which signifies inter-rater variability, improved only for the PASI area component. The deviation of scaling grading improved upon retesting by using a reference photograph. CONCLUSION:PASI assessment training improved variabilities to some degree but not for every PASI component. The development of an objective psoriasis severity assessment tool will help overcome the subjective variabilities in PASI assessment, which can never be completely eliminated via training.


Ann Dermatol


Annals of dermatology


Youn SW,Choi CW,Kim BR,Chae JB




Has Abstract


2015-10-01 00:00:00












  • Low-Dose Systemic Methotrexate Therapy for Recalcitrant Alopecia Areata.

    abstract:BACKGROUND:Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE:To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Lim SK,Lim CA,Kwon IS,Im M,Seo YJ,Kim CD,Lee JH,Lee Y

    更新日期:2017-06-01 00:00:00

  • A case of myopericytoma on the lower leg.

    abstract::Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless...

    journal_title:Annals of dermatology



    authors: Paek JO,Kang HS,Yeo KY,Yu HJ,Kim JS

    更新日期:2011-05-01 00:00:00

  • Dapsone Hypersensitivity Syndrome That Occurred during Treatment of Pediatric Patient with Erythema Elevatum Diutinum.

    abstract::Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...

    journal_title:Annals of dermatology



    authors: Kim GW,Park HJ,Kim HS,Kim SH,Ko HC,Kim BS,Kim MB

    更新日期:2011-12-01 00:00:00

  • Two Pilosebaceous Cysts with Apocrine Hidrocystoma in One Biopsy Site: A Spectrum of the Same Disease Process?

    abstract::A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...

    journal_title:Annals of dermatology



    authors: Hwang SW,Cho KJ,Oh DJ,Lee D,Kim JW,Park SW

    更新日期:2008-03-01 00:00:00

  • Preventive effects of multi-lamellar emulsion on low potency topical steroid induced local adverse effect.

    abstract:BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Sul GD,Park HJ,Bae JH,Hong KD,Park BD,Chun J,Jeong SK,Lee SH,Ahn SK,Kim HJ

    更新日期:2013-02-01 00:00:00

  • A case of isolated bowenoid papulosis of the nipple.

    abstract::Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenita...

    journal_title:Annals of dermatology



    authors: Lee HJ,Shin DH,Choi JS,Kim KH

    更新日期:2014-06-01 00:00:00

  • Cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis.

    abstract::A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granul...

    journal_title:Annals of dermatology



    authors: Chiba T,Takahara M,Nakahara T,Fukagawa S,Takei K,Shono A,Kiryu H,Moroi Y,Furue M

    更新日期:2012-02-01 00:00:00

  • Soft Tissue Infection Caused by Rapid Growing Mycobacterium following Medical Procedures: Two Case Reports and Literature Review.

    abstract::Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or ...

    journal_title:Annals of dermatology



    authors: Lin SS,Lee CC,Jang TN

    更新日期:2014-04-01 00:00:00

  • A case of complication after matridex(r) injection.

    abstract::Matridex(R) is an injectable skin filler that's composed of a mixture of cross linked hyaluronic acid and dextranomer particles, and it was recently developed for soft tissue augmentation. To the best of our knowledge, there have been few previous reports on complications associated with Matridex. We report here on a ...

    journal_title:Annals of dermatology



    authors: Huh SY,Cho S,Kim KH,An JS,Won CH,Chang SE,Lee MW,Choi JH,Moon KC

    更新日期:2010-02-01 00:00:00

  • Multiple nuchal-type fibromas on the scalp: a case report.

    abstract::Nuchal-type fibroma is a rare, benign, fibrous, tumor-like proliferation characterized by dense hypocellular bundles of collagen, with sparsely scattered fibroblasts, interspersed fat tissue, and entrapped nerve fibers. It usually develops in the posterior neck as a solitary, firm, poorly circumscribed, subcutaneous m...

    journal_title:Annals of dermatology



    authors: Kim DH,Kim TH,Sung NH,Shin H,Lee AY,Lee SH

    更新日期:2015-04-01 00:00:00

  • A Case of Extensive Pityriasis Alba.

    abstract::Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...

    journal_title:Annals of dermatology



    authors: Lee D,Kang JH,Kim SH,Seo JK,Sung HS,Hwang SW

    更新日期:2008-09-01 00:00:00

  • Erratum: Disseminated Superficial Actinic Porokeratosis in a Patient with Psoriasis, after Long-Term Narrowband Ultraviolet B Phototherapy.

    abstract::[This corrects the article on p. 211 in vol. 30, PMID: 29606819.]. ...

    journal_title:Annals of dermatology

    pub_type: 已发布勘误


    authors: Sim CY,Shin JY,Lee SY,Park YL

    更新日期:2018-08-01 00:00:00

  • Tranexamic Acid Diminishes Laser-Induced Melanogenesis.

    abstract:BACKGROUND:The treatment of post-inflammatory hyperpigmentation (PIH) remains challenging. Tranexamic acid, a well-known anti-fibrinolytic drug, has recently demonstrated a curative effect towards melasma and ultraviolet-induced PIH in Asian countries. However, the precise mechanism of its inhibitory effect on melanoge...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim MS,Bang SH,Kim JH,Shin HJ,Choi JH,Chang SE

    更新日期:2015-06-01 00:00:00

  • Intravascular cytotoxic T-cell lymphoma in a young immunocompetent woman.

    abstract::Intravascular lymphoma (IVL) is a rare disorder characterized by the presence of large neoplastic lymphoid cells restricted to the lumens of small vessels with a predilection for the skin and the central nervous system. While the vast majority of cases involving IVL are of B-cell lineage, the disease rarely affects th...

    journal_title:Annals of dermatology



    authors: Jang YH,Lee SJ,Choi YH,Lee WJ,Kim DW,Kim J,Park TI,Chae YS

    更新日期:2014-08-01 00:00:00

  • Morphologic Changes of Zebrafish Melanophore after Intense Pulsed Light and Q-Switched Nd:YAG Laser Irradiation.

    abstract:BACKGROUND:Recently, the pulse-in-pulse mode of intense pulsed light (IPL) has been used increasingly for the treatment of melasma. OBJECTIVE:To observe the morphologic changes in the melanophore in adult zebrafish after irradiation with conventional and pulse-in-pulse IPL and Q-switched Nd:YAG (QSNY) laser. METHODS:...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Ryu HJ,Lee JM,Jang HW,Park HC,Rhyu IJ,Kim IH

    更新日期:2016-12-01 00:00:00

  • Two cases of unilateral lichen planus following the lines of blaschko.

    abstract::A 50-year-old man and 71-year-old woman presented to our clinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical and histopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planu...

    journal_title:Annals of dermatology



    authors: Yayla D,Külcü Çakmak S,Oğuz ID,Gönül M,Ozhamam E,Colak A,Gül U

    更新日期:2014-10-01 00:00:00

  • A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum that Developed in a Nevus Sebaceus.

    abstract::Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp. ...

    journal_title:Annals of dermatology



    authors: Kim MS,Lee JH,Lee WM,Son SJ

    更新日期:2010-08-01 00:00:00

  • Lobulated Bowen's Disease with a Clear Cell Change.

    abstract::Bowen's disease usually manifests as a slowly enlarging erythematous scaly patch or plaque. An uncommon variant of Bowen's disease showing a verrucous appearance has been reported and a distinct variant with a prominent clear cell change on histopathology, in addition to a verrucous surface change, was also reported. ...

    journal_title:Annals of dermatology



    authors: Lee DY,Choi KH,Park SH,Lee JY,Yoon TY

    更新日期:2017-08-01 00:00:00

  • Psoriasis, Vitiligo and Crohn's Disease Co-Existing in a Single Patient: A Variant Type of Multiple Autoimmune Syndrome?

    abstract::Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...

    journal_title:Annals of dermatology



    authors: Lee SH,Kim YS,Kim HJ,Park YL

    更新日期:2017-12-01 00:00:00

  • Beneficial Effect of Low Fluence 1,064 nm Q-Switched Neodymium:Yttrium-Aluminum-Garnet Laser in the Treatment of Senile Lentigo.

    abstract:BACKGROUND:Low fluence 1,064 nm Q-switched (QS) Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment, also known as laser toning, is widely used for pigmentary disorders. There has been no reliable evaluation of the effect of low fluence 1,064 nm QS Nd:YAG laser for senile lentigo. OBJECTIVE:To investigate the b...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Nam JH,Kim HS,Lee GY,Kim WS

    更新日期:2017-08-01 00:00:00

  • A case of focal acral hyperkeratosis.

    abstract::Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-...

    journal_title:Annals of dermatology



    authors: Lee EA,Kim HS,Kim HO,Park YM

    更新日期:2009-11-01 00:00:00

  • Atrophying pityriasis versicolor: is this a new variant of pityriasis versicolor?

    abstract::An atypical clinical form of pityriasis versicolor has been infrequently reported, in which cutaneous atrophy is associated with individual pityriasis versicolor lesions. The pathogenesis of this atrophy remains unclear, but is believed to be a delayed-type hypersensitivity reaction to antigens derived from the Malass...

    journal_title:Annals of dermatology



    authors: Yang YS,Shin MK,Haw CR

    更新日期:2010-11-01 00:00:00

  • Tumor Necrosis Factor Alpha Blocker-Induced Erythrodermic Sarcoidosis in with Juvenile Rheumatoid Arthritis: A Case Report and Review of the Literature.

    abstract::The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy has not yet been reported. Herein, we report the first case of an erythrodermic ...

    journal_title:Annals of dermatology



    authors: Park SK,Hwang PH,Yun SK,Kim HU,Park J

    更新日期:2017-02-01 00:00:00

  • Cedrol Enhances Extracellular Matrix Production in Dermal Fibroblasts in a MAPK-Dependent Manner.

    abstract:BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Jin MH,Park SG,Hwang YL,Lee MH,Jeong NJ,Roh SS,Lee Y,Kim CD,Lee JH

    更新日期:2012-02-01 00:00:00

  • Insect Bite-Like Reaction with Bullous Lesions Mimicking Bullous Pemphigoid in a Patient with Chronic Lymphocytic Leukemia.

    abstract::Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...

    journal_title:Annals of dermatology



    authors: Kim JE,Kim SC

    更新日期:2018-08-01 00:00:00

  • The Effect of Detergents on the Morphology and Immunomodulatory Activity of Malassezia furfur.

    abstract:BACKGROUND:Several workers have found that Malassezia are capable of suppressing cytokine release and downregulating the phagocytic function of monocytes. But lipid-depleted Malassezia furfur (M. furfur) extracts have also been shown to induce increased production of TNF-alpha, IL-6 and IL-1beta in monocytes. We though...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim SH,Ko HC,Kim MB,Kwon KS,Oh CK

    更新日期:2009-05-01 00:00:00

  • Acral Lentiginous Melanoma, Indolent Subtype Diagnosed by En Bloc Excision: A Case Report.

    abstract::Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...

    journal_title:Annals of dermatology



    authors: Ohn J,Bae JM,Lim JS,Park JS,Yoon HS,Cho S,Park HS

    更新日期:2017-06-01 00:00:00

  • Basal cell carcinoma-mimicking lesions in korean clinical settings.

    abstract:BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim HS,Kim TW,Mun JH,Song M,Ko HC,Kim BS,Kim MB

    更新日期:2014-08-01 00:00:00

  • Effects of VitabridC12 on Skin Inflammation.

    abstract:BACKGROUND:VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE:In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis. METHODS:Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic der...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Lee JH,Jeon YJ,Choi JH,Kim HY,Kim TY

    更新日期:2017-10-01 00:00:00

  • Transoral Cross-Lip (Abbé-Estlander) Flap as a Viable and Effective Reconstructive Option in Middle Lower Lip Defect Reconstruction.

    abstract::The Abbé-Estlander flap surgery is a cross-lip procedure that is valuable in repairing a defect on the lower lip using a full-thickness flap, consisting of the skin, muscle and mucosa, from the upper lip. As usefulness and practicality of the flap in reconstruction of lower lip surgical defects in Asian ethnicity have...

    journal_title:Annals of dermatology



    authors: Hahn HJ,Kim HJ,Choi JY,Lee SY,Lee YB,Kim JW,Yu DS

    更新日期:2017-04-01 00:00:00