Reduction of Inter-Rater and Intra-Rater Variability in Psoriasis Area and Severity Index Assessment by Photographic Training.


BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PASI assessment. OBJECTIVE:In the present study, we aimed to investigate whether photographic training improves inter-rater and intra-rater variabilities. We also determined which PASI component has the greatest impact on variability. METHODS:Twenty-one dermatologists received 1 hour of PASI training. They were tested before and after the training to evaluate intra-rater variability. The physicians were further tested after training by using a reference photograph. RESULTS:The mean of each PASI component was underevaluated compared with scoring by a PASI expert. The concordance rate with the expert's grading was highest for thickness followed by erythema, scaling, and area. The scaling score showed the greatest improvement after training. After training, the distribution of deviation from the expert's grading, which signifies inter-rater variability, improved only for the PASI area component. The deviation of scaling grading improved upon retesting by using a reference photograph. CONCLUSION:PASI assessment training improved variabilities to some degree but not for every PASI component. The development of an objective psoriasis severity assessment tool will help overcome the subjective variabilities in PASI assessment, which can never be completely eliminated via training.


Ann Dermatol


Annals of dermatology


Youn SW,Choi CW,Kim BR,Chae JB




Has Abstract


2015-10-01 00:00:00












  • Basal cell carcinoma-mimicking lesions in korean clinical settings.

    abstract:BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim HS,Kim TW,Mun JH,Song M,Ko HC,Kim BS,Kim MB

    更新日期:2014-08-01 00:00:00

  • Angiolymphoid hyperplasia with eosinophilia on the palm.

    abstract::Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon dermal angioproliferating tumor, characterized by red to brown papules or nodules on the head and neck, though also occurring in the mouth, trunk, extremities and inguinal area. The palm is a very unusual site for ALHE, and there have been very few case...

    journal_title:Annals of dermatology



    authors: Kim SM,Yoon J,Yoon TJ

    更新日期:2010-08-01 00:00:00

  • Association of CDKAL1 Polymorphisms with Early-Onset Atopic Dermatitis in Koreans.

    abstract:Background:Atopic dermatitis (AD) has increased in frequency to rates as high as 20% for children in developed countries. AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. Thus, a broad understanding of genetic background is needed for early diagnosi...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Heo WI,Park KY,Lee MK,Kim JH,Moon NJ,Seo SJ

    更新日期:2018-06-01 00:00:00

  • Effect of probiotics on the treatment of children with atopic dermatitis.

    abstract:BACKGROUND:Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in recent years to find new ways of treating and preventing atopic derm...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Yeşilova Y,Çalka Ö,Akdeniz N,Berktaş M

    更新日期:2012-05-01 00:00:00

  • Expression of sfrp2 is increased in catagen of hair follicles and inhibits keratinocyte proliferation.

    abstract:BACKGROUND:Hair follicles undergo cycles of repeated growth and regression. The Wnt pathway plays an important role in the regeneration and differentiation of hair follicles. Sfrp2, a Wnt inhibitor, is involved in the developmental and disease processes of various cells and tissues by modulating the Wnt pathway. OBJEC...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim BK,Yoon SK

    更新日期:2014-02-01 00:00:00

  • A Case of Idiopathic Eruptive Macular Pigmentation Limited to Flexural Areas.

    abstract::Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages ...

    journal_title:Annals of dermatology



    authors: Kim EH,Lee ES,Kim YC,Kang HY

    更新日期:2008-06-01 00:00:00

  • Interferon-alpha Induced Sarcoidosis with Cutaneous Involvement along the Lines of Venous Drainage.

    abstract::Sarcoidosis is a systemic inflammatory disease of an unknown origin and it is characterized by the presence of noncaseating epitheloid cell granulomas in multiple organs. Herein we report on a case of cutaneous and pulmonary sarcoidosis that was associated with interferon alpha treatment for hepatitis C. A 39-year-old...

    journal_title:Annals of dermatology



    authors: Lee YB,Lee JI,Park HJ,Cho BK,Oh ST

    更新日期:2011-05-01 00:00:00

  • A Case of Extensive Pityriasis Alba.

    abstract::Pityriasis alba (PA) is a common benign disease, characterized by hypopigmented macules or patches on the face, usually seen in children. However, two uncommon variants exist, a pigmenting type and an extensive type. Extensive PA is rare. The lesions tend to be less scaly, more persistent, more generalized, more symme...

    journal_title:Annals of dermatology



    authors: Lee D,Kang JH,Kim SH,Seo JK,Sung HS,Hwang SW

    更新日期:2008-09-01 00:00:00

  • Acquired Brachial Cutaneous Dyschromatosis in a Middle Aged Male.

    abstract::Acquired brachial cutaneous dyschromatosis (ABCD) is an acquired disorder of pigmentary change that presents as chronic, asymptomatic, geographic-shaped, gray-brown patches, consisting of mixed hyper and hypopigmented macules on the dorsal aspect of the forearms. We report a case of a 40-year-old male who presented wi...

    journal_title:Annals of dermatology



    authors: Choi MJ,Byun JY,Choi HY,Choi YW

    更新日期:2018-06-01 00:00:00

  • Sox9 Increases the Proliferation and Colony-forming Activity of Outer Root Sheath Cells Cultured In Vitro.

    abstract:BACKGROUND:β-catenin plays a pivotal role in hair follicle development and hair growth cycle. OBJECTIVE:The aim of this study was to identify β-catenin-regulated genes in cultured human hair outer root sheath (ORS) cells. METHODS:Primary cultured ORS cells were transduced with recombinant adenovirus expressing N-term...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Shi G,Sohn KC,Kim SY,Ryu EK,Park YS,Lee Y,Seo YJ,Lee JH,Kim CD

    更新日期:2011-05-01 00:00:00

  • Soft Tissue Infection Caused by Rapid Growing Mycobacterium following Medical Procedures: Two Case Reports and Literature Review.

    abstract::Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or ...

    journal_title:Annals of dermatology



    authors: Lin SS,Lee CC,Jang TN

    更新日期:2014-04-01 00:00:00

  • Congenital and multiple hobnail hemangiomas.

    abstract::Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...

    journal_title:Annals of dermatology



    authors: Yoon SY,Kwon HH,Jeon HC,Lee JH,Cho S

    更新日期:2011-11-01 00:00:00

  • Deep penetrating benign fibrous histiocytoma of the foot associated with throbbing pain.

    abstract::Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walki...

    journal_title:Annals of dermatology



    authors: Chung J,Namkoong S,Sim JH,Lee JS,Hong SP,Kim MH,Park BC

    更新日期:2011-10-01 00:00:00

  • Chemokine Receptor CCR3 Expression in Malignant Cutaneous Tumors.

    abstract:BACKGROUND:Chemokines and their receptors are important players in tumorigenesis by facilitating tumor proliferation and metastasis. Little is known about the possible function of chemokine receptors in relation to the development and progression of malignant cutaneous tumors. OBJECTIVE:The aim of this study was to de...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Lee YJ,Kim DH,Lee SH,Nam HS,Roh MR,Cho MK

    更新日期:2010-11-01 00:00:00

  • Progressive macular hypomelanosis in korean patients: a clinicopathologic study.

    abstract:BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Hwang SW,Hong SK,Kim SH,Park JH,Seo JK,Sung HS,Lee D

    更新日期:2009-08-01 00:00:00

  • Change in Antimicrobial Susceptibility of Skin-Colonizing Staphylococcus aureus in Korean Patients with Atopic Dermatitis during Ten-Year Period.

    abstract:BACKGROUND:A small subset of adolescents atopic dermatitis (AD) tends to persist. This also leads to get more antibiotics exposure with advancing years. Antibiotic resistance has been regarded as a serious problem during Staphylococcus aureus treatment, especially methicillin-resistant S. aureus (MRSA). OBJECTIVE:It w...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Park JM,Jo JH,Jin H,Ko HC,Kim MB,Kim JM,Kim DW,Jang HS,Kim BS

    更新日期:2016-08-01 00:00:00

  • Transoral Cross-Lip (Abbé-Estlander) Flap as a Viable and Effective Reconstructive Option in Middle Lower Lip Defect Reconstruction.

    abstract::The Abbé-Estlander flap surgery is a cross-lip procedure that is valuable in repairing a defect on the lower lip using a full-thickness flap, consisting of the skin, muscle and mucosa, from the upper lip. As usefulness and practicality of the flap in reconstruction of lower lip surgical defects in Asian ethnicity have...

    journal_title:Annals of dermatology



    authors: Hahn HJ,Kim HJ,Choi JY,Lee SY,Lee YB,Kim JW,Yu DS

    更新日期:2017-04-01 00:00:00

  • The Investigation on the Distribution of Malassezia Yeasts on the Normal Korean Skin by 26S rDNA PCR-RFLP.

    abstract:BACKGROUND:Malassezia yeasts are normal flora of the skin that are discovered in 75~98% of health subjects, but since its association with various skin disorders have been known, many studies have been conducted in the distribution of the yeasts. OBJECTIVE:To isolate, identify, and classify Malassezia yeasts from the ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Jang SJ,Lim SH,Ko JH,Oh BH,Kim SM,Song YC,Yim SM,Lee YW,Choe YB,Ahn KJ

    更新日期:2009-02-01 00:00:00

  • Risk Factors Affecting Adverse Effects of Cyclosporine A in a Real-World Psoriasis Treatment.

    abstract:Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim BR,Yang S,Doh EJ,Choi CW,Youn SW

    更新日期:2018-04-01 00:00:00

  • Disseminated Superficial Porokeratosisin a Patient with Gastric Cancer.

    abstract::Disseminated superficial porokeratosis (DSP) is a rare variant of porokeratosis, which is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. DSP is usually associated with immunosuppressive states and hematopoietic malignancies, but rarely with malignancies of visc...

    journal_title:Annals of dermatology



    authors: Kim SW,Min SU,Won CH,Cho S

    更新日期:2008-12-01 00:00:00

  • The Effect of Detergents on the Morphology and Immunomodulatory Activity of Malassezia furfur.

    abstract:BACKGROUND:Several workers have found that Malassezia are capable of suppressing cytokine release and downregulating the phagocytic function of monocytes. But lipid-depleted Malassezia furfur (M. furfur) extracts have also been shown to induce increased production of TNF-alpha, IL-6 and IL-1beta in monocytes. We though...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim SH,Ko HC,Kim MB,Kwon KS,Oh CK

    更新日期:2009-05-01 00:00:00

  • Acral Lentiginous Melanoma, Indolent Subtype Diagnosed by En Bloc Excision: A Case Report.

    abstract::Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...

    journal_title:Annals of dermatology



    authors: Ohn J,Bae JM,Lim JS,Park JS,Yoon HS,Cho S,Park HS

    更新日期:2017-06-01 00:00:00

  • Retinoid Induces the Degradation of Corneodesmosomes and Downregulation of Corneodesmosomal Cadherins: Implications on the Mechanism of Retinoid-induced Desquamation.

    abstract:BACKGROUND:Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE:The aim of this study was to investigate the effect of retinoid on the expression of corneodesmosomal components ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim MY,Lee SE,Chang JY,Kim SC

    更新日期:2011-11-01 00:00:00

  • Lack of association of plasma histamine with diamine oxidase in chronic idiopathic urticaria.

    abstract:BACKGROUND:Chronic idiopathic urticaria (CIU) is considered a complex and multifactorial disease. Excessive histamine intake may induce an attack of urticaria. The main enzyme for histamine metabolism is diamine oxidase (DAO). OBJECTIVE:Plasma histamine concentrations and DAO activities were evaluated to determine whe...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Cho HJ,Cho SI,Kim HO,Park CW,Lee CH

    更新日期:2013-05-01 00:00:00

  • Correlation between Severity of Atopic Dermatitis and Sleep Quality in Children and Adults.

    abstract:BACKGROUND:The atopic dermatitis (AD) can limit a patient's physical and psychosocial development as well as lower their overall quality of life (QOL), including sleep quality. OBJECTIVE:The purpose of this study was to evaluate the relationships between clinical disease severity, QOL and sleep quality in children and...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kong TS,Han TY,Lee JH,Son SJ

    更新日期:2016-06-01 00:00:00

  • Acute localized exanthematous pustulosis on the face.

    abstract::Acute localized exanthematous pustulosis (ALEP) is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 26-year-old woman presented with multiple erythematous pustules on her face, which had appeared th...

    journal_title:Annals of dermatology



    authors: Sim HS,Seol JE,Chun JS,Seo JK,Lee D,Sung HS

    更新日期:2011-12-01 00:00:00

  • Impact of postthyroidectomy scar on the quality of life of thyroid cancer patients.

    abstract:BACKGROUND:Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy. OBJECTIVE:To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Choi Y,Lee JH,Kim YH,Lee YS,Chang HS,Park CS,Roh MR

    更新日期:2014-12-01 00:00:00

  • Multiple nuchal-type fibromas on the scalp: a case report.

    abstract::Nuchal-type fibroma is a rare, benign, fibrous, tumor-like proliferation characterized by dense hypocellular bundles of collagen, with sparsely scattered fibroblasts, interspersed fat tissue, and entrapped nerve fibers. It usually develops in the posterior neck as a solitary, firm, poorly circumscribed, subcutaneous m...

    journal_title:Annals of dermatology



    authors: Kim DH,Kim TH,Sung NH,Shin H,Lee AY,Lee SH

    更新日期:2015-04-01 00:00:00

  • A case of isolated bowenoid papulosis of the nipple.

    abstract::Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenita...

    journal_title:Annals of dermatology



    authors: Lee HJ,Shin DH,Choi JS,Kim KH

    更新日期:2014-06-01 00:00:00

  • Lobulated Bowen's Disease with a Clear Cell Change.

    abstract::Bowen's disease usually manifests as a slowly enlarging erythematous scaly patch or plaque. An uncommon variant of Bowen's disease showing a verrucous appearance has been reported and a distinct variant with a prominent clear cell change on histopathology, in addition to a verrucous surface change, was also reported. ...

    journal_title:Annals of dermatology



    authors: Lee DY,Choi KH,Park SH,Lee JY,Yoon TY

    更新日期:2017-08-01 00:00:00