Abstract：
BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PASI assessment. OBJECTIVE:In the present study, we aimed to investigate whether photographic training improves inter-rater and intra-rater variabilities. We also determined which PASI component has the greatest impact on variability. METHODS:Twenty-one dermatologists received 1 hour of PASI training. They were tested before and after the training to evaluate intra-rater variability. The physicians were further tested after training by using a reference photograph. RESULTS:The mean of each PASI component was underevaluated compared with scoring by a PASI expert. The concordance rate with the expert's grading was highest for thickness followed by erythema, scaling, and area. The scaling score showed the greatest improvement after training. After training, the distribution of deviation from the expert's grading, which signifies inter-rater variability, improved only for the PASI area component. The deviation of scaling grading improved upon retesting by using a reference photograph. CONCLUSION:PASI assessment training improved variabilities to some degree but not for every PASI component. The development of an objective psoriasis severity assessment tool will help overcome the subjective variabilities in PASI assessment, which can never be completely eliminated via training.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Youn SW,Choi CW,Kim BR,Chae JBdoi
10.5021/ad.2015.27.5.557subject
Has Abstractpub_date
2015-10-01 00:00:00pages
557-62issue
5eissn
1013-9087issn
2005-3894journal_volume
27pub_type
杂志文章abstract：BACKGROUND:The atopic dermatitis (AD) can limit a patient's physical and psychosocial development as well as lower their overall quality of life (QOL), including sleep quality. OBJECTIVE:The purpose of this study was to evaluate the relationships between clinical disease severity, QOL and sleep quality in children and...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.3.321
更新日期：2016-06-01 00:00:00
abstract：:Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2015.27.3.315
更新日期：2015-06-01 00:00:00
abstract：:Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2008.20.2.98
更新日期：2008-06-01 00:00:00
abstract：:Actinomycotic infections are known to have an association with difficulties in diagnosis and treatment. These infections usually involve the head, neck, thorax, and abdomen. Actinomycosis of the upper lip is a rare condition and an important one as well, because it can imitate other diseases. As the initial impression...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S1.S131
更新日期：2011-09-01 00:00:00
abstract：:Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2014.26.2.236
更新日期：2014-04-01 00:00:00
abstract：Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2018.30.2.143
更新日期：2018-04-01 00:00:00
abstract：:The Abbé-Estlander flap surgery is a cross-lip procedure that is valuable in repairing a defect on the lower lip using a full-thickness flap, consisting of the skin, muscle and mucosa, from the upper lip. As usefulness and practicality of the flap in reconstruction of lower lip surgical defects in Asian ethnicity have...
journal_title：Annals of dermatology
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doi：10.5021/ad.2017.29.2.210
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in recent years to find new ways of treating and preventing atopic derm...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2012.24.2.189
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:Hair follicles undergo cycles of repeated growth and regression. The Wnt pathway plays an important role in the regeneration and differentiation of hair follicles. Sfrp2, a Wnt inhibitor, is involved in the developmental and disease processes of various cells and tissues by modulating the Wnt pathway. OBJEC...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.1.79
更新日期：2014-02-01 00:00:00
abstract：:Sarcoidosis is a systemic inflammatory disease of an unknown origin and it is characterized by the presence of noncaseating epitheloid cell granulomas in multiple organs. Herein we report on a case of cutaneous and pulmonary sarcoidosis that was associated with interferon alpha treatment for hepatitis C. A 39-year-old...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.2.239
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:The expression of c-Met is substantially elevated in most malignant human cancers. We therefore searched for c-Met expression and compared the expression level among malignant skin cancers. OBJECTIVE:The aim of this study was to determine the c-Met expression pattern and the protein expression level in sele...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2011.23.1.33
更新日期：2011-02-01 00:00:00
abstract：:Clinically, folliculosebaceous cystic hamartoma (FSCH) lacks distinct features, but it has been reported as an asymptomatic, 1- to 3-cm, dome-shaped nodule on the face. Histopathologically, FSCH is characterized by adnexal and folliculosebaceous cystic proliferation with various mesenchymal changes. This case presente...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2009.21.1.63
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2012.24.1.16
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2015.27.6.709
更新日期：2015-12-01 00:00:00
abstract：:We report on a rare case of fluconazole induced fixed drug eruption in a 62-year old female patient. She was referred to our department for multiple erythematous itchy maculopatches on the face, neck, both upper arms, and trunk area, which had occurred over the previous 6 months. Her attending physician prescribed flu...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S1.S1
更新日期：2011-09-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2017.29.5.618
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Chronic idiopathic urticaria (CIU) is considered a complex and multifactorial disease. Excessive histamine intake may induce an attack of urticaria. The main enzyme for histamine metabolism is diamine oxidase (DAO). OBJECTIVE:Plasma histamine concentrations and DAO activities were evaluated to determine whe...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.2.189
更新日期：2013-05-01 00:00:00
abstract：:Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspect...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2013.25.3.352
更新日期：2013-08-01 00:00:00
abstract：:Fexofenadine (Allegra® 180) is a second-generation antihistamine. It is widely used as anti-allergic drug, which suppresses various allergic reactions mediated by histamines. A few cases of H1-antihistamine-induced urticaria have been reported. Herein, we report a rare case of fexofenadine-induced urticaria which was ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S3.S329
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.4.431
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:β-catenin plays a pivotal role in hair follicle development and hair growth cycle. OBJECTIVE:The aim of this study was to identify β-catenin-regulated genes in cultured human hair outer root sheath (ORS) cells. METHODS:Primary cultured ORS cells were transduced with recombinant adenovirus expressing N-term...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2011.23.2.138
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:The clinical symptoms of facial and truncal acne differ. Skin surface acidity (pH), which is affected by sebum secretions, reflects the different clinical characteristics of the face and trunk. However, no studies have been conducted on truncal sebum production and skin pH. OBJECTIVE:We evaluated the differ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.2.216
更新日期：2016-04-01 00:00:00
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journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.4.456
更新日期：2010-11-01 00:00:00
abstract：:Disseminated superficial porokeratosis (DSP) is a rare variant of porokeratosis, which is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. DSP is usually associated with immunosuppressive states and hematopoietic malignancies, but rarely with malignancies of visc...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2008.20.4.193
更新日期：2008-12-01 00:00:00
abstract：:Entecavir (Baraclude®, Bristol-Myers Squibb) is a potent and selective antiviral agent that has demonstrated efficacy in patients with chronic hepatitis B. The most frequent adverse events attributed to entecavir include increased alanine aminotransferase, upper respiratory tract infection, headache, abdominal pain, c...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2013.25.4.493
更新日期：2013-11-01 00:00:00
abstract：:Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2008.20.4.267
更新日期：2008-12-01 00:00:00
abstract：:Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.3.405
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2015.27.4.371
更新日期：2015-08-01 00:00:00
abstract：:Telogen effluvium is categorized in nonscarring alopecia, which shows scalp hair thinning and shedding diffusely resulting from inducing factors such as physiological stressful events and several acute or chronic diseases. It usually appears in female patients following parturition, as well as after febrile disease, m...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2018.30.2.214
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Computer-aided image analysis (CAIA) has been suggested as an effective diagnostic tool for pigmented skin lesions (PSLs), especially melanoma. However, few studies on benign PSLs have been reported. OBJECTIVE:The purpose of this study was to evaluate benign PSLs with our CAIA software and analyze the diffe...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.3.314
更新日期：2014-06-01 00:00:00
