A granulomatous drug eruption induced by entecavir.

Abstract:

:Entecavir (Baraclude®, Bristol-Myers Squibb) is a potent and selective antiviral agent that has demonstrated efficacy in patients with chronic hepatitis B. The most frequent adverse events attributed to entecavir include increased alanine aminotransferase, upper respiratory tract infection, headache, abdominal pain, cough, pyrexia, fatigue, and diarrhea. Although quite a few randomized double-blind studies including ones investigating adverse events along with these general symptoms have been reported, few cases of cutaneous adverse events have been described in detail. We demonstrate a case of granulomatous drug eruption as a cutaneous adverse event induced by entecavir.

journal_name

Ann Dermatol

journal_title

Annals of dermatology

authors

Yoon J,Park D,Kim C

doi

10.5021/ad.2013.25.4.493

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

493-5

issue

4

eissn

1013-9087

issn

2005-3894

journal_volume

25

pub_type

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