Abstract:
BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze the clinical and histopathological features of a relatively large number of cases of diagnosed SK. METHODS:Two hundred and seventy-one pathology slides of skin tissue from patients with clinically diagnosed SK and 206 cases of biopsy-proven SK were analyzed. The biopsy-proven cases of SK were assessed for histopathological subclassification. The demographic, clinical, and histopathological data of the patients were collected for analysis of associated factors. RESULTS:The most frequent histopathological subtype was the acanthotic type, followed by mixed, hyperkeratotic, melanoacanthoma, clonal, irritated, and adenoid types; an unexpectedly high percentage (9.2%) of the melanoacanthoma variant was observed. The adenoid type was more common in sun-exposed sites than in sun-protected sites (p=0.028). Premalignant and malignant entities together represented almost one-quarter (24.2%) of the clinicopathological mismatch cases (i.e., mismatch between the clinical and histopathological diagnoses). Regarding the location of SK development, the frequency of mismatch for the sun-exposed areas was significantly higher than that for sun-protected areas (p=0.043). CONCLUSION:The adenoid type was more common in sun-exposed sites. Biopsy sampling should be performed for lesions situated in sun-exposed areas to exclude other premalignant or malignant diseases.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Roh NK,Hahn HJ,Lee YW,Choe YB,Ahn KJdoi
10.5021/ad.2016.28.2.152subject
Has Abstractpub_date
2016-04-01 00:00:00pages
152-8issue
2eissn
1013-9087issn
2005-3894journal_volume
28pub_type
杂志文章abstract:BACKGROUND:Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE:The objective of this study is to characteriz...
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abstract::Telogen effluvium is categorized in nonscarring alopecia, which shows scalp hair thinning and shedding diffusely resulting from inducing factors such as physiological stressful events and several acute or chronic diseases. It usually appears in female patients following parturition, as well as after febrile disease, m...
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journal_title:Annals of dermatology
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journal_title:Annals of dermatology
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journal_title:Annals of dermatology
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journal_title:Annals of dermatology
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