Acral Lentiginous Melanoma, Indolent Subtype Diagnosed by En Bloc Excision: A Case Report.


:Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious for malignancy. Acral lentiginous melanoma was not detected in punch and longitudinal biopsy specimens, but en bloc excision tissue revealed melanoma. Acral lentiginous melanoma is known to have a heterogeneous pathologic manifestation depending on the pigmented region and the time it takes to progress. In this regard, en bloc excision can be considered as a first-line biopsy technique to diagnose acral lentiginous melanoma, indolent subtype.


Ann Dermatol


Annals of dermatology


Ohn J,Bae JM,Lim JS,Park JS,Yoon HS,Cho S,Park HS




Has Abstract


2017-06-01 00:00:00












  • Enhancement of keratinocyte differentiation by rose absolute oil.

    abstract:BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim JH,Choi DK,Lee SS,Choi SJ,Kim CD,Yoon TJ,Lee JH

    更新日期:2010-08-01 00:00:00

  • Erratum: Disseminated Superficial Actinic Porokeratosis in a Patient with Psoriasis, after Long-Term Narrowband Ultraviolet B Phototherapy.

    abstract::[This corrects the article on p. 211 in vol. 30, PMID: 29606819.]. ...

    journal_title:Annals of dermatology

    pub_type: 已发布勘误


    authors: Sim CY,Shin JY,Lee SY,Park YL

    更新日期:2018-08-01 00:00:00

  • Erratum: ERRATUM.

    abstract::[This corrects the article on p. 217 in vol. 21.]. ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章



    更新日期:2009-08-01 00:00:00

  • Two cases of eosinophilic fasciitis.

    abstract::Eosinophic fasciitis (EF) is an uncommon connective tissue disease characterized by scleroderma-like cutaneous changes, peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate (ESR). Typical histopathologic findings include chronic inflammatory infiltration affecting the deep fa...

    journal_title:Annals of dermatology



    authors: Chun JH,Lee KH,Sung MS,Park CJ

    更新日期:2011-02-01 00:00:00

  • Efficacy of microneedling plus human stem cell conditioned medium for skin rejuvenation: a randomized, controlled, blinded split-face study.

    abstract:BACKGROUND:The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role of growth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied and no controlled trials have been performed. OBJECTIVE:We evaluated the anti...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Lee HJ,Lee EG,Kang S,Sung JH,Chung HM,Kim DH

    更新日期:2014-10-01 00:00:00

  • A Case of Varicella Combined with Hand-foot-mouth Disease in a Healthy Child.

    abstract::We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm reve...

    journal_title:Annals of dermatology



    authors: Na SY,Son YM,Lee HY,Baek JO,Roh JY,Lee JR

    更新日期:2009-02-01 00:00:00

  • A case of membranous lipodystrophy observed in lichen amyloidosis.

    abstract::Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogen...

    journal_title:Annals of dermatology



    authors: Lee Y,Ahn SY,Ji JH,Hong SP,Bak H,Lee SH,Ahn SK

    更新日期:2009-05-01 00:00:00

  • Cedrol Enhances Extracellular Matrix Production in Dermal Fibroblasts in a MAPK-Dependent Manner.

    abstract:BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Jin MH,Park SG,Hwang YL,Lee MH,Jeong NJ,Roh SS,Lee Y,Kim CD,Lee JH

    更新日期:2012-02-01 00:00:00

  • A case of myopericytoma on the lower leg.

    abstract::Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless...

    journal_title:Annals of dermatology



    authors: Paek JO,Kang HS,Yeo KY,Yu HJ,Kim JS

    更新日期:2011-05-01 00:00:00

  • Tranexamic Acid Diminishes Laser-Induced Melanogenesis.

    abstract:BACKGROUND:The treatment of post-inflammatory hyperpigmentation (PIH) remains challenging. Tranexamic acid, a well-known anti-fibrinolytic drug, has recently demonstrated a curative effect towards melasma and ultraviolet-induced PIH in Asian countries. However, the precise mechanism of its inhibitory effect on melanoge...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim MS,Bang SH,Kim JH,Shin HJ,Choi JH,Chang SE

    更新日期:2015-06-01 00:00:00

  • A Case of Idiopathic Eruptive Macular Pigmentation Limited to Flexural Areas.

    abstract::Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages ...

    journal_title:Annals of dermatology



    authors: Kim EH,Lee ES,Kim YC,Kang HY

    更新日期:2008-06-01 00:00:00

  • The clinical efficacy, safety and functionality of anion textile in the treatment of atopic dermatitis.

    abstract:BACKGROUND:Several previous studies have suggested the improvement of atopic dermatitis (AD) in response to special fabrics. In particular, beneficial effects have been reported, following the use of anion textiles. OBJECTIVE:The purpose of this study is to evaluate the effectiveness and safety of an anion textile in ...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Kim SH,Hwang SH,Hong SK,Seo JK,Sung HS,Park SW,Shin JH

    更新日期:2012-11-01 00:00:00

  • Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers.

    abstract:BACKGROUND:Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier. OBJECTIVE:We examined whether kinetin induces skin barrier functions in vitro and in vivo. METHODS:To evaluate the efficacy of kinetin a...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: An S,Cha HJ,Ko JM,Han H,Kim SY,Kim KS,Lee SJ,An IS,Kim S,Youn HJ,Ahn KJ,Kim SY

    更新日期:2017-02-01 00:00:00

  • Efficacy and Safety of Calcipotriol/Betamethasone Dipropionate Ointment for the Treatment of Trachyonychia: An Open-Label Study.

    abstract:BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Park JM,Cho HH,Kim WJ,Mun JH,Song M,Kim HS,Ko HC,Kim BS,Kim MB

    更新日期:2015-08-01 00:00:00

  • Clinical and Histopathological Investigation of Seborrheic Keratosis.

    abstract:BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Roh NK,Hahn HJ,Lee YW,Choe YB,Ahn KJ

    更新日期:2016-04-01 00:00:00

  • Intralesional methotrexate for the treatment of keratoacanthoma: retrospective study and review of the korean literature.

    abstract:BACKGROUND:Although intralesional methotrexate (MTX) is an effective, nonsurgical treatment of keratoacanthoma (KA), there have not been many reports of on the MTX treatment for KA in Korea. OBJECTIVE:The purpose of this study was to evaluate the clinical efficacy of the intralesional MTX for the treatment of KA in Ko...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Yoo MG,Kim IH

    更新日期:2014-04-01 00:00:00

  • Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study.

    abstract:Background:Atopic dermatitis (AD) is related to a deficiency of delta-6-desaturase, an enzyme responsible for converting linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) as a source of GLA has been of interest in the management of AD. Objective:The aim of this randomized, double-blinded, placebo...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Chung BY,Park SY,Jung MJ,Kim HO,Park CW

    更新日期:2018-08-01 00:00:00

  • Angiolymphoid hyperplasia with eosinophilia on the palm.

    abstract::Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon dermal angioproliferating tumor, characterized by red to brown papules or nodules on the head and neck, though also occurring in the mouth, trunk, extremities and inguinal area. The palm is a very unusual site for ALHE, and there have been very few case...

    journal_title:Annals of dermatology



    authors: Kim SM,Yoon J,Yoon TJ

    更新日期:2010-08-01 00:00:00

  • A case of childhood lichen aureus.

    abstract::Lichen aureus is a rare type of chronic pigmented purpuric dermatosis. The eruptions consist of discrete or confluent golden to brownish lichenoid macules and papules, and are usually asymptomatic. Lichen aureus commonly occurs in young adults, but less frequently in children. We report the first case of multiple lich...

    journal_title:Annals of dermatology



    authors: Kim MJ,Kim BY,Park KC,Youn SW

    更新日期:2009-11-01 00:00:00

  • Impact of Different Spa Waters on Inflammation Parameters in Human Keratinocyte HaCaT Cells.

    abstract:BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Zöller N,Valesky E,Hofmann M,Bereiter-Hahn J,Bernd A,Kaufmann R,Meissner M,Kippenberger S

    更新日期:2015-12-01 00:00:00

  • Transoral Cross-Lip (Abbé-Estlander) Flap as a Viable and Effective Reconstructive Option in Middle Lower Lip Defect Reconstruction.

    abstract::The Abbé-Estlander flap surgery is a cross-lip procedure that is valuable in repairing a defect on the lower lip using a full-thickness flap, consisting of the skin, muscle and mucosa, from the upper lip. As usefulness and practicality of the flap in reconstruction of lower lip surgical defects in Asian ethnicity have...

    journal_title:Annals of dermatology



    authors: Hahn HJ,Kim HJ,Choi JY,Lee SY,Lee YB,Kim JW,Yu DS

    更新日期:2017-04-01 00:00:00

  • Touraine-soulente-golé syndrome: a rare case report and review of the literature.

    abstract::Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspect...

    journal_title:Annals of dermatology



    authors: Kumar S,Sidhu S,Mahajan BB

    更新日期:2013-08-01 00:00:00

  • A Case of p-ANCA-Positive Propylthiouracil-Induced Pyoderma Gangrenosum.

    abstract::Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...

    journal_title:Annals of dermatology



    authors: Seo JW,Son HH,Choi JH,Lee SK

    更新日期:2010-02-01 00:00:00

  • Psoriasis, Vitiligo and Crohn's Disease Co-Existing in a Single Patient: A Variant Type of Multiple Autoimmune Syndrome?

    abstract::Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...

    journal_title:Annals of dermatology



    authors: Lee SH,Kim YS,Kim HJ,Park YL

    更新日期:2017-12-01 00:00:00

  • Two Pilosebaceous Cysts with Apocrine Hidrocystoma in One Biopsy Site: A Spectrum of the Same Disease Process?

    abstract::A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...

    journal_title:Annals of dermatology



    authors: Hwang SW,Cho KJ,Oh DJ,Lee D,Kim JW,Park SW

    更新日期:2008-03-01 00:00:00

  • Acute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells: Implications for Hair Growth.

    abstract:BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of r...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Shin H,Choi SJ,Cho AR,Kim DY,Kim KH,Kwon O

    更新日期:2016-10-01 00:00:00

  • TNF, IL12B, and IFNG Gene Polymorphisms in Serbian Patients with Psoriasis.

    abstract:BACKGROUND:Psoriasis is a common chronic inflammatory skin disease with a strong genetic basis. Cytokines such as tumor necrosis factor alpha (TNF-α), interleukins (ILs) such are IL-12 and IL-23, and interferon gamma (IFN-γ) are released from various inflammatory and resident cells, and have been implicated in the init...

    journal_title:Annals of dermatology

    pub_type: 杂志文章


    authors: Popadic S,Savic E,Markovic M,Ramic Z,Medenica L,Pravica V,Spuran Z,Trajkovic V,Popadic D

    更新日期:2015-04-01 00:00:00

  • Pigmented Basal cell carcinoma of the nipple-areola complex in an elderly woman.

    abstract::Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy. The nipple-areola complex (NAC) is an uncommon site for BCC to develop. BCCs in this region display more aggressive behavior and a greater potential to spread than when found i...

    journal_title:Annals of dermatology



    authors: Jung HJ,Jun JH,Kim HY,Lee SJ,Kim DW,Lee WJ,Jung JH

    更新日期:2011-10-01 00:00:00

  • Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas.

    abstract::Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...

    journal_title:Annals of dermatology



    authors: Park J,Cho YS,Song KH,Lee JS,Yun SK,Kim HU

    更新日期:2011-08-01 00:00:00

  • Localized Sweet's Syndrome in an Irradiated Field.

    abstract::Sweet's syndrome is a reactive dermatosis characterized clinically by fever, leukocytosis, and multiple, erythematous, painful plaques. Histopathologic examination reveals a band-like dense dermal inflammatory infiltrate composed mainly of neutrophils with papillary dermal edema, and no features of vasculitis. We repo...

    journal_title:Annals of dermatology



    authors: Lee GY,Do MO,Kim SH,Choi HY,Myung KB,Choi YW

    更新日期:2009-08-01 00:00:00