Abstract：
:Although more than 90% of melanomas have cutaneous origins, melanomas sometimes present metastatically with no apparent primary lesion. A 62-year-old female presented with black pigmentation on her left thumbnail that had begun 2 years earlier and after the biopsy, she was diagnosed with malignant melanoma. Interestingly, 7 years earlier, a 4 cm palpable mass on her left axilla had been diagnosed as melanoma from an unknown primary site (MUP) with the involvement of an axillary lymph node. We speculate that the melanoma of the left thumb was the primary site and the melanoma in the axilla was a metastasis from the left thumb, and suggest several hypotheses explaining the appearance of the primary lesion as acral lentiginous melanoma after detecting a metastatic site. We consider this case interesting because it helps us to understand the pathogenesis of MUP and reminds physicians to conduct careful periodical work-ups of melanoma patients, and highlights the importance of continued long-term follow-up, especially for patients with MUP.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Lee S,Lee HJ,Oh SH,Im M,Lee JH,Seo YJ,Lee Ydoi
10.5021/ad.2011.23.S2.S274subject
Has Abstractpub_date
2011-10-01 00:00:00pages
S274-8issue
Suppl 2eissn
1013-9087issn
2005-3894journal_volume
23pub_type
abstract：BACKGROUND:β-catenin plays a pivotal role in hair follicle development and hair growth cycle. OBJECTIVE:The aim of this study was to identify β-catenin-regulated genes in cultured human hair outer root sheath (ORS) cells. METHODS:Primary cultured ORS cells were transduced with recombinant adenovirus expressing N-term...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2011.23.2.138
更新日期：2011-05-01 00:00:00
abstract：:Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-ass...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2017.29.5.618
更新日期：2017-10-01 00:00:00
abstract：:Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2014.26.2.236
更新日期：2014-04-01 00:00:00
abstract：:Entecavir (Baraclude®, Bristol-Myers Squibb) is a potent and selective antiviral agent that has demonstrated efficacy in patients with chronic hepatitis B. The most frequent adverse events attributed to entecavir include increased alanine aminotransferase, upper respiratory tract infection, headache, abdominal pain, c...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2013.25.4.493
更新日期：2013-11-01 00:00:00
abstract：:Matridex(R) is an injectable skin filler that's composed of a mixture of cross linked hyaluronic acid and dextranomer particles, and it was recently developed for soft tissue augmentation. To the best of our knowledge, there have been few previous reports on complications associated with Matridex. We report here on a ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.1.81
更新日期：2010-02-01 00:00:00
abstract：:Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S3.S290
更新日期：2011-12-01 00:00:00
abstract：:Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2018.30.4.468
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Computer-aided image analysis (CAIA) has been suggested as an effective diagnostic tool for pigmented skin lesions (PSLs), especially melanoma. However, few studies on benign PSLs have been reported. OBJECTIVE:The purpose of this study was to evaluate benign PSLs with our CAIA software and analyze the diffe...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2014.26.3.314
更新日期：2014-06-01 00:00:00
abstract：:Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abd...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.2.219
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE:The aim of this study was to investigate the effect of retinoid on the expression of corneodesmosomal components ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2011.23.4.439
更新日期：2011-11-01 00:00:00
abstract：:Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon dermal angioproliferating tumor, characterized by red to brown papules or nodules on the head and neck, though also occurring in the mouth, trunk, extremities and inguinal area. The palm is a very unusual site for ALHE, and there have been very few case...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.3.358
更新日期：2010-08-01 00:00:00
abstract：:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a vascular tumor affecting the limbs or trunk. Characteristically, the lesion has a "targetoid" clinical feature and dilated vascular spaces lined by hobnail endothelial cells at histologic examination. The age of onset is widely variable, form 5~67 years, typ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.4.539
更新日期：2011-11-01 00:00:00
abstract：:An atypical clinical form of pityriasis versicolor has been infrequently reported, in which cutaneous atrophy is associated with individual pityriasis versicolor lesions. The pathogenesis of this atrophy remains unclear, but is believed to be a delayed-type hypersensitivity reaction to antigens derived from the Malass...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2010.22.4.456
更新日期：2010-11-01 00:00:00
abstract：:Actinomycotic infections are known to have an association with difficulties in diagnosis and treatment. These infections usually involve the head, neck, thorax, and abdomen. Actinomycosis of the upper lip is a rare condition and an important one as well, because it can imitate other diseases. As the initial impression...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S1.S131
更新日期：2011-09-01 00:00:00
abstract：:A 50-year-old man and 71-year-old woman presented to our clinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical and histopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planu...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2014.26.5.636
更新日期：2014-10-01 00:00:00
abstract：:Sarcoidosis is a systemic inflammatory disease of an unknown origin and it is characterized by the presence of noncaseating epitheloid cell granulomas in multiple organs. Herein we report on a case of cutaneous and pulmonary sarcoidosis that was associated with interferon alpha treatment for hepatitis C. A 39-year-old...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.2.239
更新日期：2011-05-01 00:00:00
abstract：:Pityriasis versicolor is a superficial infection of the stratum corneum, which is caused by the Malassezia species. Tge Malassezia species consist of 12 subspecies, including M. furfur, M. pachydermatis, M. symphodialis and M. globasa. The Malassezia species are classified as a normal flora, particularly in the sebum ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2012.24.3.345
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.3.261
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2010.22.3.255
更新日期：2010-08-01 00:00:00
abstract：:Fexofenadine (Allegra® 180) is a second-generation antihistamine. It is widely used as anti-allergic drug, which suppresses various allergic reactions mediated by histamines. A few cases of H1-antihistamine-induced urticaria have been reported. Herein, we report a rare case of fexofenadine-induced urticaria which was ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2011.23.S3.S329
更新日期：2011-12-01 00:00:00
abstract：Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2018.30.2.143
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier. OBJECTIVE:We examined whether kinetin induces skin barrier functions in vitro and in vivo. METHODS:To evaluate the efficacy of kinetin a...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2017.29.1.6
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Hair loss and hair growth is the subject of tremendous amount of research. OBJECTIVE:This study investigated the efficacy of three chemical treatments used in humans for hair loss, using a rat model of hair regrowth. The products tested were 2% minoxidil, Hairgrow (Dar-Al-Dawa Pharma), Aminexil, Dercos (Vic...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2016.28.1.65
更新日期：2016-02-01 00:00:00
abstract：:Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenita...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2014.26.3.381
更新日期：2014-06-01 00:00:00
abstract：:[This corrects the article on p. 211 in vol. 30, PMID: 29606819.]. ...
journal_title：Annals of dermatology
pub_type： 已发布勘误
doi：10.5021/ad.2018.30.4.511
更新日期：2018-08-01 00:00:00
abstract：:Intravascular lymphoma (IVL) is a rare disorder characterized by the presence of large neoplastic lymphoid cells restricted to the lumens of small vessels with a predilection for the skin and the central nervous system. While the vast majority of cases involving IVL are of B-cell lineage, the disease rarely affects th...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2014.26.4.496
更新日期：2014-08-01 00:00:00
abstract：:[This corrects the article on p. 217 in vol. 21.]. ...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2009.21.3.335
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Chronic idiopathic urticaria (CIU) is considered a complex and multifactorial disease. Excessive histamine intake may induce an attack of urticaria. The main enzyme for histamine metabolism is diamine oxidase (DAO). OBJECTIVE:Plasma histamine concentrations and DAO activities were evaluated to determine whe...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.2.189
更新日期：2013-05-01 00:00:00
abstract：:The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy has not yet been reported. Herein, we report the first case of an erythrodermic ...
journal_title：Annals of dermatology
pub_type：
doi：10.5021/ad.2017.29.1.74
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. OBJECTIVE:We aimed to evaluate the effectiveness and preference of topical immunother...
journal_title：Annals of dermatology
pub_type： 杂志文章
doi：10.5021/ad.2013.25.4.434
更新日期：2013-11-01 00:00:00
