Abstract:
BACKGROUND:Stress is a known cause of hair loss in many species. OBJECTIVE:In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS:Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of rat and human dermal papilla cells (hDPCs), as well as serum cortisol and corticotropin-releasing hormone levels, were measured. Mast cell staining was performed on the biopsied tissue. In addition, Western blot and quantitative real time polymerase chain reaction were used to assess mast cell tryptase and cytokine expression, respectively in rat skin biopsies. RESULTS:Stress-serum treatment reduced significantly the number of viable hDPCs and arrested the cell cycle in the G1 phase, compared to serum from unrestrained rats (p<0.05, respectively). Moreover, restrained rats had significantly higher levels of cortisol in serum than unrestrained rats (p<0.01). Acute stress serum increased mast cell numbers and mast cell tryptase expression, as well as inducing interleukin (IL)-6 and IL-1β up-regulation. CONCLUSION:These results suggest that acute stress also has an inhibitory effect on hair growth via cortisol release in addition to substance P-mast cell pathway.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Shin H,Choi SJ,Cho AR,Kim DY,Kim KH,Kwon Odoi
10.5021/ad.2016.28.5.600subject
Has Abstractpub_date
2016-10-01 00:00:00pages
600-606issue
5eissn
1013-9087issn
2005-3894journal_volume
28pub_type
杂志文章abstract:BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.6.709
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy. OBJECTIVE:To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.6.693
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2010.22.3.255
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abstract::Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.3.405
更新日期:2011-08-01 00:00:00
abstract::A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eru...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.1.11
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Chemokines and their receptors are important players in tumorigenesis by facilitating tumor proliferation and metastasis. Little is known about the possible function of chemokine receptors in relation to the development and progression of malignant cutaneous tumors. OBJECTIVE:The aim of this study was to de...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2010.22.4.412
更新日期:2010-11-01 00:00:00
abstract::Hematodermic neoplasm (HN) is a clinically aggressive neoplasm with a high incidence of cutaneous involvement and a risk of leukemic dissemination. In the recent WHO-EORTC classification, the term blastic natural killer cell lymphoma has been replaced with CD4+/CD56+ HN because of its derivation from a plasmacytoid de...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.2.186
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD). OBJECTIVE:The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution. METH...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.3.292
更新日期:2013-08-01 00:00:00
abstract::A 50-year-old man and 71-year-old woman presented to our clinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical and histopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planu...
journal_title:Annals of dermatology
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doi:10.5021/ad.2014.26.5.636
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journal_title:Annals of dermatology
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doi:10.5021/ad.2011.23.S3.S329
更新日期:2011-12-01 00:00:00
abstract::Blastomycosis-like pyoderma is a rare, vegetating skin lesion that is an unusual exaggerated tissue reaction possibly to prolonged primary or secondary bacterial infection. We report a case of blastomycosis-like pyoderma in a man with Down syndrome, diabetes mellitus and hypothyroidism who responsed poorly to conventi...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.3.365
更新日期:2011-08-01 00:00:00
abstract::Epidermolysis bullosa (EB) is a rare hereditary disorder characterized by formation of blisters following minor trauma. It has been traditionally categorized by the level of basement membrane zone separation into EB simplex (EBS), junctional EB (JEB), and dystrophic EB (DEB). Recently, hemidesmosomal EB has been propo...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S1.S41
更新日期:2011-09-01 00:00:00
abstract::We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm reve...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.1.98
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE:The aim of this study was to investigate the effect of retinoid on the expression of corneodesmosomal components ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2011.23.4.439
更新日期:2011-11-01 00:00:00
abstract::Nicolau syndrome is a rare adverse reaction to a variety of intra-muscular drug preparations. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, hemorrhagic patch, and finally, necrosis of skin, subcutaneous fat, and muscle tissue. The phenomenon has ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.4.501
更新日期:2011-11-01 00:00:00
abstract::Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walki...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S239
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in recent years to find new ways of treating and preventing atopic derm...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.2.189
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:There is evidence that glycosaminoglycans (GAGs) are present in the hair shaft within the follicle but there are no studies regarding GAGs isolation and measurement in the human hair shaft over the scalp surface, it means, in the free hair shaft. OBJECTIVE:The purpose of our research was to isolate and meas...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.5.533
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.3.261
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abstract:BACKGROUND:Psoriasis is a common chronic inflammatory skin disease with a strong genetic basis. Cytokines such as tumor necrosis factor alpha (TNF-α), interleukins (ILs) such are IL-12 and IL-23, and interferon gamma (IFN-γ) are released from various inflammatory and resident cells, and have been implicated in the init...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.2.128
更新日期:2015-04-01 00:00:00
abstract::Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower b...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.4.233
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.6.711
更新日期:2016-12-01 00:00:00
abstract::Acute localized exanthematous pustulosis (ALEP) is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 26-year-old woman presented with multiple erythematous pustules on her face, which had appeared th...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S3.S368
更新日期:2011-12-01 00:00:00
abstract::[This corrects the article on p. 211 in vol. 30, PMID: 29606819.]. ...
journal_title:Annals of dermatology
pub_type: 已发布勘误
doi:10.5021/ad.2018.30.4.511
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.4.371
更新日期:2015-08-01 00:00:00
abstract::Acantholytic squamous cell carcinoma is a well-defined variant of squamous cell cancer in which significant portions of the neoplastic proliferation show a pseudoglandular or tubular microscopic pattern. It usually presents as a nodule with various colors, and it is accompanied by scaling, crusting, and ulceration on ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.4.267
更新日期:2008-12-01 00:00:00
abstract::Melanocytic nevi are subject to change with age in both clinical and histopathologic findings. In 1991, Cho et al. first reported three cases of lobulated intradermal nevi and suggested their cases represented an unusual form of regressing melanocytic nevus. Herein we report four cases of lobulated intradermal nevus a...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.1.115
更新日期:2011-02-01 00:00:00
abstract::Multiple autoimmune syndrome (MAS) is a rare condition, in which at least three well-defined autoimmune diseases co-occur in a single patient. Although the pathogenesis of MAS remains poorly understood, genetic, immunological, hormonal, and environmental factors may all play a role. Although three classic subtypes of ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2017.29.6.782
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Gray hair naturally develops in the process of human aging. Many people with gray hair periodically dye their hair. Hair dyeing products are widely used and they can cause adverse effects. Therefore, the user's knowledge and recognition about hair dyeing and related side effects are important. OBJECTIVE:The...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.3.274
更新日期:2012-08-01 00:00:00
abstract::Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.1.48
更新日期:2010-02-01 00:00:00