Abstract:
BACKGROUND:Recent epidemiologic studies have shown that environmental contaminants such as air pollution and tobacco smoke play an important role in the pathophysiology of atopic dermatitis (AD). OBJECTIVE:The aim of this study was to evaluate the relationship between the severity of AD and indoor air pollution. METHODS:The study population consisted of 425 children from 9 kindergartens, Korea. The authors surveyed the prevalence of AD and evaluated disease severity by the eczema area and severity index (EASI) score and investigator's global assessment (IGA). After measuring indoor air pollution, a program to improve indoor air quality was conducted in 9 kindergartens. Seven months later, the prevalence and disease severity were evaluated. RESULTS:The initial prevalence of AD was 8% and the mean EASI score was 2.37. The levels of particulate material 10 (PM10) and carbon dioxide (CO2) were higher in some kindergartens compared to the normal values. Subsequent to the completion of the indoor air quality improvement program, the mean PM10 level was significantly decreased from 182.7 to 73.4 µg/m(3). After the completion of the program, the prevalence of AD and the mean EASI were decreased, and the changes were both statistically significant. The mean number of hospital visits decreased from 1.3 per month during the first survey to 0.7 per month during the second survey, which was statistically significant. CONCLUSION:Indoor air pollution could be related to AD. The reduction of PM10 through improving indoor air quality should be considered in kindergartens and schools in order to prevent and relieve AD in children.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Kim HO,Kim JH,Cho SI,Chung BY,Ahn IS,Lee CH,Park CWdoi
10.5021/ad.2013.25.3.292subject
Has Abstractpub_date
2013-08-01 00:00:00pages
292-7issue
3eissn
1013-9087issn
2005-3894journal_volume
25pub_type
杂志文章abstract:BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.1.5
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:The clinical symptoms of facial and truncal acne differ. Skin surface acidity (pH), which is affected by sebum secretions, reflects the different clinical characteristics of the face and trunk. However, no studies have been conducted on truncal sebum production and skin pH. OBJECTIVE:We evaluated the differ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.2.216
更新日期:2016-04-01 00:00:00
abstract::Although more than 90% of melanomas have cutaneous origins, melanomas sometimes present metastatically with no apparent primary lesion. A 62-year-old female presented with black pigmentation on her left thumbnail that had begun 2 years earlier and after the biopsy, she was diagnosed with malignant melanoma. Interestin...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S274
更新日期:2011-10-01 00:00:00
abstract::Acute localized exanthematous pustulosis (ALEP) is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 26-year-old woman presented with multiple erythematous pustules on her face, which had appeared th...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S3.S368
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role of growth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied and no controlled trials have been performed. OBJECTIVE:We evaluated the anti...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.5.584
更新日期:2014-10-01 00:00:00
abstract::Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.2.98
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.2.152
更新日期:2016-04-01 00:00:00
abstract::Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.1.48
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Psoriasis is a common chronic inflammatory skin disease with a strong genetic basis. Cytokines such as tumor necrosis factor alpha (TNF-α), interleukins (ILs) such are IL-12 and IL-23, and interferon gamma (IFN-γ) are released from various inflammatory and resident cells, and have been implicated in the init...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.2.128
更新日期:2015-04-01 00:00:00
abstract::An atypical clinical form of pityriasis versicolor has been infrequently reported, in which cutaneous atrophy is associated with individual pityriasis versicolor lesions. The pathogenesis of this atrophy remains unclear, but is believed to be a delayed-type hypersensitivity reaction to antigens derived from the Malass...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.4.456
更新日期:2010-11-01 00:00:00
abstract::Eccrine porocarcinoma is a rare neoplasm that originates from the intraepidermal ductal portion of the eccrine sweat gland, and it usually occurs on the pre-existing lesion of benign eccine poroma. Its occurrence is more common in females and elderly persons. We present a case of a 44-year-old man who suffered from ec...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S1.S79
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy. OBJECTIVE:To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.6.693
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.3.261
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Angiogenesis is crucial for wound healing and exogenous supplements of the angiogenic growth factors have been known to promote cutaneous wound healing. Angiopoietin (Ang) 1 is a recently discovered angiogenic factor and there have been few studies of its effect on cutaneous wound healing. OBJECTIVE:We exam...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2008.20.2.49
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Multiplex polymerase chain reaction (PCR) allows more than two target DNA molecules to be amplified with more than two primers. This method is also useful for detecting various other organisms simultaneously within a single test tube, and the scope of its use has been expanding widely in the field of clinica...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2011.23.3.304
更新日期:2011-08-01 00:00:00
abstract::Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2015.27.3.315
更新日期:2015-06-01 00:00:00
abstract:Background:Atopic dermatitis (AD) is related to a deficiency of delta-6-desaturase, an enzyme responsible for converting linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) as a source of GLA has been of interest in the management of AD. Objective:The aim of this randomized, double-blinded, placebo...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.4.409
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.4.371
更新日期:2015-08-01 00:00:00
abstract::Leiomyosarcomas are uncommon malignant smooth muscle tumors, mainly derived from vessels or viscera. Superficial leiomyosarcomas are a rare soft tissue sarcoma arising from the dermis or subcutaneous tissue in the skin. According to tumor origin and location, they are divided into cutaneous and subcutaneous leiomyosar...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2013.25.2.237
更新日期:2013-05-01 00:00:00
abstract::Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S3.S290
更新日期:2011-12-01 00:00:00
abstract::Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy. The nipple-areola complex (NAC) is an uncommon site for BCC to develop. BCCs in this region display more aggressive behavior and a greater potential to spread than when found i...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S201
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Several workers have found that Malassezia are capable of suppressing cytokine release and downregulating the phagocytic function of monocytes. But lipid-depleted Malassezia furfur (M. furfur) extracts have also been shown to induce increased production of TNF-alpha, IL-6 and IL-1beta in monocytes. We though...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.2.130
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Patients with atopic dermatitis (AD) should be relatively well informed about the disorder to control their condition and prevent flare-ups. Thus far, there is no accurate information about the disease awareness levels and therapeutic behavior of AD patients. OBJECTIVE:To collect data on patients' knowledge...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.1.40
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:The treatment of post-inflammatory hyperpigmentation (PIH) remains challenging. Tranexamic acid, a well-known anti-fibrinolytic drug, has recently demonstrated a curative effect towards melasma and ultraviolet-induced PIH in Asian countries. However, the precise mechanism of its inhibitory effect on melanoge...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.3.250
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Short stature is sometimes seen in children with atopic dermatitis (AD); however, the topic has never been studied systematically. OBJECTIVE:The aim of this study was to show whether AD itself affects stature in children and to evaluate the influence of other relevant factors such as genetic background, die...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.1.23
更新日期:2013-02-01 00:00:00
abstract::Focal acral hyperkeratosis (FAH) is a rare genodermatosis with an autosomal dominant pattern of inheritance; however, it may also be sporadic. FAH is characterized by late-onset crateriform keratotic papules, some coalescing into plaques, along the borders of the hands and feet. We herein report a case of FAH in a 47-...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.4.426
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:A small subset of adolescents atopic dermatitis (AD) tends to persist. This also leads to get more antibiotics exposure with advancing years. Antibiotic resistance has been regarded as a serious problem during Staphylococcus aureus treatment, especially methicillin-resistant S. aureus (MRSA). OBJECTIVE:It w...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.4.470
更新日期:2016-08-01 00:00:00
abstract::Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2017.29.3.327
更新日期:2017-06-01 00:00:00
abstract::Melanocytic nevi are subject to change with age in both clinical and histopathologic findings. In 1991, Cho et al. first reported three cases of lobulated intradermal nevi and suggested their cases represented an unusual form of regressing melanocytic nevus. Herein we report four cases of lobulated intradermal nevus a...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.1.115
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.6.709
更新日期:2015-12-01 00:00:00