Abstract:
:Acute localized exanthematous pustulosis (ALEP) is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 26-year-old woman presented with multiple erythematous pustules on her face, which had appeared three days after taking antibiotics. Histopathological findings showed subcorneal pustules and mixed inflammatory cell infiltration in the dermis. The pustules were resolved within 2 weeks after the patient discontinued the antibiotics. Herein, we present a case of a woman with a cutaneous drug reaction consistent with ALEP that occurred subsequent to administration of antibiotics.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Sim HS,Seol JE,Chun JS,Seo JK,Lee D,Sung HSdoi
10.5021/ad.2011.23.S3.S368subject
Has Abstractpub_date
2011-12-01 00:00:00pages
S368-70issue
Suppl 3eissn
1013-9087issn
2005-3894journal_volume
23pub_type
abstract::Lichen aureus is a rare type of chronic pigmented purpuric dermatosis. The eruptions consist of discrete or confluent golden to brownish lichenoid macules and papules, and are usually asymptomatic. Lichen aureus commonly occurs in young adults, but less frequently in children. We report the first case of multiple lich...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.4.393
更新日期:2009-11-01 00:00:00
abstract::The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy has not yet been reported. Herein, we report the first case of an erythrodermic ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2017.29.1.74
更新日期:2017-02-01 00:00:00
abstract:Background:Atopic dermatitis (AD) has increased in frequency to rates as high as 20% for children in developed countries. AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. Thus, a broad understanding of genetic background is needed for early diagnosi...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.3.276
更新日期:2018-06-01 00:00:00
abstract::Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who p...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.1.48
更新日期:2010-02-01 00:00:00
abstract::Blue nevi are characterized by a collection of pigment-producing melanocytes in the dermis. These lesions clinically present as well demarcated cerulean-blue or bluish black colored papules or plaques that usually measure less than 1 cm in diameter. They are typically found on the dorsal surface of the hands and feet ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.1.119
更新日期:2010-02-01 00:00:00
abstract::Acute generalized exanthematous pustulosis (AGEP) is a cutaneous reaction principally induced by drugs. Spontaneous resolution is observed in most patients. However, severe cases required systemic corticosteroid administration. Hydroxychloroquine, which is used to treat some dermatologic and rheumatologic diseases bec...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2015.27.4.431
更新日期:2015-08-01 00:00:00
abstract::Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particu...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.3.405
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Gray hair naturally develops in the process of human aging. Many people with gray hair periodically dye their hair. Hair dyeing products are widely used and they can cause adverse effects. Therefore, the user's knowledge and recognition about hair dyeing and related side effects are important. OBJECTIVE:The...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.3.274
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE:This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS:A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All pati...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.4.371
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Severity grading is important for the assessment of psoriasis treatment efficacy. This is most commonly achieved by using the psoriasis area and severity index (PASI), a subjective tool with inherent inter-rater and intra-rater variability. PASI-naive dermatologists require training to properly conduct a PAS...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.5.557
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE:To clarify the...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.4.431
更新日期:2014-08-01 00:00:00
abstract::A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granul...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2012.24.1.74
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE:The aim of this study was to identify the active ingredient that enhances ECM production in dermal fibroblasts. METHODS...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.1.16
更新日期:2012-02-01 00:00:00
abstract::[This corrects the article on p. 217 in vol. 21.]. ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2009.21.3.335
更新日期:2009-08-01 00:00:00
abstract::Hydroa vacciniforme (HV) is a photosensitivity disorder characterized by recurrent necrotic vesiculopapules on sun-exposed areas, which heal spontaneously during adolescence. Recently, an association has been reported between latent Epstein-Barr virus (EBV) infection and atypical HV-like eruption and malignant potenti...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.2.209
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE:The aim of this study was to investigate the effect of retinoid on the expression of corneodesmosomal components ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2011.23.4.439
更新日期:2011-11-01 00:00:00
abstract::Vitiligo is an acquired depigmentary disorder of the skin that results from the loss of functioning epidermal melanocytes. Most studies on vitiligo have concentrated on the abnormality of melanocytes rather than the abnormality of keratinocytes; however, epidermal melanocytes form a functional and structural unit with...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2012.24.2.115
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:The treatment of different skin conditions with spa waters is a long tradition dating back to at least late Hellenism. Interestingly, independent scientific examinations studying the effect of spa waters are scarce. OBJECTIVE:In the present in vitro study, we compared the effect of culture media supplemente...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2015.27.6.709
更新日期:2015-12-01 00:00:00
abstract::Nicolau syndrome is a rare adverse reaction to a variety of intra-muscular drug preparations. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, hemorrhagic patch, and finally, necrosis of skin, subcutaneous fat, and muscle tissue. The phenomenon has ...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.4.501
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Seborrheic keratosis (SK) is one of the most common epidermal tumors of the skin. However, only a few large-scale clinicohistopathological investigations have been conducted on SK or on the possible correlation between histopathological SK subtype and location. OBJECTIVE:The aim of this study was to analyze...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.2.152
更新日期:2016-04-01 00:00:00
abstract::Compared to cutaneous benign fibrous histiocytoma (BFH), deep-seated BFH is very rare and poorly recognized. Both cutaneous and deep-seated BFH are usually asymptomatic. We herein report a 25 year-old woman who presented with a painful mass in her foot that was poorly controlled by analgesics and associated with walki...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S239
更新日期:2011-10-01 00:00:00
abstract::Nail unit melanoma is a type of acral lentiginous melanoma and requires histopathologic examination for a confirmed diagnosis. However, inadequate biopsy techniques make definitive diagnosis difficult. A 61-year-old man presented with progressive nail pigmentation for 15 years, which was clinically highly suspicious f...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2017.29.3.327
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Low fluence 1,064 nm Q-switched (QS) Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) laser treatment, also known as laser toning, is widely used for pigmentary disorders. There has been no reliable evaluation of the effect of low fluence 1,064 nm QS Nd:YAG laser for senile lentigo. OBJECTIVE:To investigate the b...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.4.427
更新日期:2017-08-01 00:00:00
abstract::Melanocytic nevi are subject to change with age in both clinical and histopathologic findings. In 1991, Cho et al. first reported three cases of lobulated intradermal nevi and suggested their cases represented an unusual form of regressing melanocytic nevus. Herein we report four cases of lobulated intradermal nevus a...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.1.115
更新日期:2011-02-01 00:00:00
abstract::This is the first case report to describe a 44-year-old woman with a history of advanced hepatocellular carcinoma who developed toxic epidermal necrolysis (TEN) clinically after taking 400 mg sorafenib (Nexavar®, BAY 43-9006) and tosufloxacin orally once per day. Both sorafenib and tosufloxacin were eventually discont...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S3.S404
更新日期:2011-12-01 00:00:00
abstract::Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in a 74-year old man with CLL. The patient presented with a 2-year history of recurrent itchy erythematous patches and bliste...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2018.30.4.468
更新日期:2018-08-01 00:00:00
abstract:Background:No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. Objective:The objective of this study was to investigate the changes of laboratory values and related risk factors in patients with ...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2018.30.2.143
更新日期:2018-04-01 00:00:00
abstract::Although more than 90% of melanomas have cutaneous origins, melanomas sometimes present metastatically with no apparent primary lesion. A 62-year-old female presented with black pigmentation on her left thumbnail that had begun 2 years earlier and after the biopsy, she was diagnosed with malignant melanoma. Interestin...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.S2.S274
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Topical steroid treatment induces diverse local Wand systemic adverse effects. Several approaches have been tried to reduce the steroid-induced adverse effects. Simultaneous application of physiological lipid mixture is also suggested. OBJECTIVE:Novel vehicles for topical glucocorticoids formulation were ev...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.1.5
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE:The objective of this study is to characteriz...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.2.143
更新日期:2017-04-01 00:00:00