Abstract:
:Inorganic polyphosphate (polyP) is found in all living organisms. The known polyP functions in eukaryotes range from osmoregulation and virulence in parasitic protozoa to modulating blood coagulation, inflammation, bone mineralization and cellular signalling in mammals. However mechanisms of regulation and even the identity of involved proteins in many cases remain obscure. Most of the insights obtained so far stem from studies in the yeast Saccharomyces cerevisiae. Here, we provide a short overview of the properties and functions of known yeast polyP metabolism enzymes and discuss future directions for polyP research.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Gerasimaitė R,Mayer Adoi
10.1042/BST20150213subject
Has Abstractpub_date
2016-02-01 00:00:00pages
234-9issue
1eissn
0300-5127issn
1470-8752pii
BST20150213journal_volume
44pub_type
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