Abstract:
:Cardiovascular disease risk factor and mortality data collected since the 1978 Conference on the Decline in Coronary Heart Disease Mortality were reviewed. Risk factor and disease trends were generally parallel and compatible with current hypotheses of cause and prevention. A few discrepancies between risk factors and disease change were noted and discussed. Models were presented for estimating effects of risk factor and medical care changes on disease trends. Their usefulness and limitations were considered. An ongoing need was elaborated for systematic and innovative surveillance research to expand and improve the capability to measure, explain, and predict disease trends. Rational public health policy depends on competent and sustained surveillance.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Blackburn Hsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
S210-5issue
3 Suppl 1eissn
0300-5771issn
1464-3685journal_volume
18pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:This study aims to evaluate the contribution of the reduction in major cardiovascular diseases (CVD), malignant neoplasms (MN), accidents and AIDS mortality to the gains in life expectancy observed during the decade 1985-1994, as well as to calculate and compare the potential gains due to the partial or tota...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.5.905
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies. METHO...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyq207
更新日期:2011-04-01 00:00:00
abstract:Background:Existing studies of the 1944-45 Dutch famine found little evidence of the association between early life malnutrition and midlife cognition. Methods:Among 2446 rural participants born between 1958 and 1963 in the China Health and Retirement Longitudinal Study, we examined effects of exposure to China's 1959...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyx222
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Human herpes virus 8 (HHV8) appears to be the primary aetiologic agent of Kaposi sarcoma (KS). To study the distribution of HHV8, a seroepidemiological study was carried out in western Sicily, where a high incidence rate of classical KS is well documented. METHODS:A total of 970 sera of healthy human immuno...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.1.175
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Nitrogen dioxide (NO(2)), an oxidant gas that contaminates both outdoor and indoor air, is considered to be a potential risk factor for asthma. We investigated concurrently the effects of outdoor and indoor NO(2) on the prevalence and incidence of respiratory symptoms among children. METHODS:A cohort study ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.5.862
更新日期:2000-10-01 00:00:00
abstract::In recent years a strong case has been made in support of a viral aetiology for at least some primary hepatocellular carcinoma (PHC) in areas of low incidence. By pooling routinely collected cancer registration and infection data, study of the relationship between hepatitis B virus (HBV) infection and the incidence of...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.60
更新日期:1991-03-01 00:00:00
abstract::The association between social ties and survival was assessed using a stratified sample of 1060 elderly aged 60-89 years in the city of Tampere, Finland. During the 6.5-year follow-up, 240 men and 153 women died. Compared with married men, the death rate ratio among unmarried men was 1.7 and among widowers 1.2. The re...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.1.158
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:A genetic component of early-onset lung cancer has been suggested. The role of metabolic gene polymorphisms has never been studied in young lung cancer cases. Phase 1 and Phase 2 gene polymorphisms are involved in tobacco carcinogens' metabolism and therefore in lung cancer risk. METHODS:The effect of metab...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyg001
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Life history theory and resource dilution models of the family suggest that siblings may present a threat to healthy development because they compete for resources that parents have available to invest in individual offspring. Using data from a large cohort study of contemporary British families (ALSPAC), we...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn116
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Violent criminality is at least moderately heritable, but the mechanisms behind this remain largely unexplained. Height, a highly heritable trait, may be involved but no study has estimated the effect of height on crime while simultaneously accounting for important demographic, biological and other heritable...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt274
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:It is widely believed that children of high socioeconomic status (SES) are more likely than those of low SES to develop acute lymphoblastic leukaemia (ALL). Such observations have led to wide-ranging speculations about the potential aetiological role of factors associated with affluence and modernization. M...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyl193
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Complicated HIV transmission dynamics make it unclear how to design and interpret results from community-randomized controlled trials (CRCT) of interventions to prevent infection. METHODS:Mathematical modelling was used to investigate the effectiveness of interventions to prevent HIV transmission aimed at h...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym232
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:It is unclear when in the life course do social inequalities in inflammation emerge. We examined whether the association between socioeconomic position (SEP) and C-reactive protein (CRP) is determined at conception, in childhood, adolescence or adulthood in 1484 participants from the population-based Cardiov...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym244
更新日期:2008-04-01 00:00:00
abstract::In the Hérault region of France, vineyards cover an area of 128,000 hectares (60% of agricultural land) and involve more than 93% of farms. A vine-growing exposure matrix was built for assessing pesticide exposure. It is based on information obtained from a survey among 85 vine-growers who lived in Hérault and who had...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.supplement_2.s36
更新日期:1993-01-01 00:00:00
abstract::Biological interference among viral agents might have significant implications for disease prevention and therapy. Field data for influenza yield conflicting evidence concerning the independence of infection rates, or disease severity, for two co-circulating viruses. To examine the effects of several assumed modes of ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.2.444
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Present understanding of increased risk of Epstein-Barr virus (EBV)-related infectious mononucleosis among children of low birth order or small sibships is mainly based on old and indirect evidence. Societal changes and methodological limitations of previous studies call for new data. METHODS:We used data f...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyu118
更新日期:2014-10-01 00:00:00
abstract::Occupation and industry classifications are used in epidemiological studies to classify study subjects according to their job and subsequently to study risk by job, to infer social class indicators, or to infer exposure to specific agents through job-exposure matrices. However, documentation on methodological aspects ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyg080
更新日期:2003-06-01 00:00:00
abstract::At the request of the COMAC EPID committee of the Commission of the European Communities the author visited all the countries of the EEC except Luxembourg in 1983-84 in order to prepare a report on 'Upgrading in epidemiology'. The report was presented at a meeting organized by COMAC EPID in April 1984 and subsequently...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/15.4.449
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:Ciprofloxacin, ceftriaxone and pivmecillinam are the antibiotics currently recommended by the World Health Organization (WHO) for the treatment of dysentery in children; yet there have been no reviews of the clinical effectiveness of these antibiotics in recent years. METHODS:We reviewed all literature repo...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyq024
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Despite abundant evidence that lower education is associated with a higher risk of smoking, whether the association is causal has not been convincingly established. METHODS:We investigated the association between education and lifetime smoking patterns in a birth cohort established in 1959 and followed thro...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym250
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Tuberculosis has been declining in developed countries for a long time, as a result of the intrinsic epidemiological characteristics of this disease, combined with improvement in the standard of living and more recently the use of antibiotics. In these low prevalence countries, decisions concerning the objec...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.1.190
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:Exposure to a pre-natal famine environment has been associated with a persistent decrease in DNA methylation of the IGF2 gene, although study findings on other loci have been highly variable. There have been no studies to date of the relation between pre-natal famine and overall global DNA methylation in adu...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyr137
更新日期:2012-02-01 00:00:00
abstract::Geographical variations in the declining rates of ischaemic heart disease (IHD) mortality may provide clues about various environmental risk factors responsible as a mass influence on the population IHD rate. The rate of IHD decline in 18 of 21 NJ counties was 2 to 45% less than the USA national rate of decline. The o...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.1.26
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Anxiety or depression symptoms may increase the risk of developing asthma, and their interaction with obesity is not known. We aimed to assess the association of anxiety or depression symptoms and the joint association of these symptoms and obesity with incident asthma. METHODS:We conducted a prospective co...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt151
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:A growing body of evidence supports the role of type 2 diabetes as an individual-level risk factor for tuberculosis (TB), though evidence from developing countries with the highest TB burdens is lacking. In developing countries, TB is most common among the poor, in whom diabetes may be less common. We assess...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyq238
更新日期:2011-04-01 00:00:00
abstract::Trachoma was considered to have been 'eradicated' from the state of São Paulo, Brazil, until 1982 when a number of new cases of trachoma were reported in preschool children in Bebedouro, a small town in northwestern São Paulo. A household survey was undertaken to assess the prevalence and epidemiological characteristi...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.1.169
更新日期:1992-02-01 00:00:00
abstract::Spontaneous losses between the 5th and 27th weeks of pregnancy were measured in a prospective study of 32 123 women whose contraceptive history around the time of conception was known. Diaphragm use prior to conception was associated with a significant reduction in second-trimester losses, after taking into account th...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/9.1.49
更新日期:1980-03-01 00:00:00
abstract:BACKGROUND:There are several existing systematic reviews of prevalence of dementia for mainland China, Hong Kong and Taiwan, but several studies have been newly reported. The aim of this study is to update prevalence data in this region and test for variation across geographical areas and time periods using the new dat...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy007
更新日期:2018-06-01 00:00:00
abstract::A prediction of the end-stage renal disease (ESRD) population in Japan from 1980 to 2000 was made using a system dynamics model based on previously published estimates. It is estimated that the ESRD population will be 145,750 (1111 per million population (pmp)) by the year 2000, if renal transplantation gradually incr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.4.1032
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:Previous studies do not provide a clear picture of the relationship between nitrogen dioxide (NO(2)) exposure and asthma. METHODS:Eighteen schools using unflued gas heating in winter were randomly allocated to either retain their heaters (10 control schools) or to have replacement flued gas or electric heat...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/dyh018
更新日期:2004-02-01 00:00:00