Abstract：
:Current nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy and physiology of these nerves to highlight their potential as a donor graft. The aim of this study was to identify and characterise the structural and extracellular matrix (ECM) components of porcine peripheral nerves in the hind leg. Methods included the dissection of porcine nerves, localisation, characterisation and quantification of the ECM components and identification of nerve cells. Results showed a noticeable variance between porcine and rat nerve (a commonly studied species) in terms of fascicle number. The study also revealed that when porcine peripheral nerves branch, a decrease in fascicle number and size was evident. Porcine ECM and nerve fascicles were found to be predominately comprised of collagen together with glycosaminoglycans, laminin and fibronectin. Immunolabelling for nerve growth factor receptor p75 also revealed the localisation of Schwann cells around and inside the fascicles. In conclusion, it is shown that porcine peripheral nerves possess a microstructure similar to that found in rat, and is not dissimilar to human. This finding could extend to the suggestion that due to the similarities in anatomy to human nerve, porcine nerves may have utility as a nerve graft providing guidance and support to regenerating axons.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Zilic L,Garner PE,Yu T,Roman S,Haycock JW,Wilshaw SPdoi
10.1111/joa.12341subject
Has Abstractpub_date
2015-09-01 00:00:00pages
302-14issue
3eissn
0021-8782issn
1469-7580journal_volume
227pub_type
杂志文章abstract：:The canine's olfactory acuity is legendary, but neither its main olfactory system nor its vomeronasal system has been described in much detail. We used immunohistochemistry on paraffin-embedded sections of male and female adult dog vomeronasal organ (VNO) to characterize the expression of proteins known to be expresse...
journal_title：Journal of anatomy
pub_type： 更正并重新发布的文章,杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Injury to the energy-storing superficial digital flexor tendon is common in equine athletes and is age-related. Tenocytes in the superficial digital flexor tendon of adult horses appear to have limited ability to respond adaptively to exercise or prevent the accumulation of strain-induced microdamage. It has been sugg...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00781.x
更新日期：2007-09-01 00:00:00
abstract：:It is well accepted that the aortic plexus is a network of pre- and post-ganglionic nerves overlying the abdominal aorta, which is primarily involved with the sympathetic innervation to the mesenteric, pelvic and urogenital organs. Because a comprehensive anatomical description of the aortic plexus and its connections...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12251
更新日期：2015-01-01 00:00:00
abstract：:Age at death estimation of human skeletal remains is one of the key issues in constructing a biological profile both in forensic and archaeological contexts. The traditional adult osteological methods evaluate macroscopically the morphological changes that occur with increasing age of specific skeletal indicators, suc...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/joa.12544
更新日期：2019-08-01 00:00:00
abstract：:The histogenesis of the isocortical segment of the lateral telencephalic wall at the coronal level of the interventricular foramen was studied in mice between the ages of E10 and the adult. The proliferative activity of the periventricular germinal layers was correlated with changes in cell distributions in the interm...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-05-01 00:00:00
abstract：:There is an accumulating body of evidence that highlights the fact that one can identify convergence in programmes of cellular differentiation. That is, that a particular differentiated cell/tissue type can be generated via non-identical paths. Convergence is also seen in evolution and here it is termed homoplasy, thu...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2010.01232.x
更新日期：2010-06-01 00:00:00
abstract：:The primary cilium is a ubiquitous cytoplasmic organelle of unknown function. Ultrastructural evidence of primary cilia in chondrocytes, and their colocalisation with the Golgi apparatus, has led to speculation that these structures are functionally linked. To investigate the relationship between these organelles, we ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19940393.x
更新日期：2001-10-01 00:00:00
abstract：:Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12677
更新日期：2017-12-01 00:00:00
abstract：:The aim of this study was to design, develop and employ a method for the acquisition of a significant data base of thickness measurements. The integration of standard histological techniques (step serial sectioning), modern computer technology and a personally developed software package (specifically designed for thic...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophage...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:The lymphoid tissues of the red-tailed phascogale (Phascogale calura) were examined using histological and immunohistochemical techniques. The distribution of immune cells in the tissue beds was documented using antibodies to surface markers CD3 and an MHC Class II antigen (equivalent to HLA DRII). Spleen, gut-associa...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00530.x
更新日期：2006-03-01 00:00:00
abstract：:Schwann cells are excluded from the CNS during development by the glial limiting membrane, an area of astrocytic specialisation present at the nerve root transitional zone, and at blood vessels in the neuropil. This barrier, however, can be disrupted and, with the highly migratory nature of Schwann cells, can result i...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1997.19010035.x
更新日期：1997-01-01 00:00:00
abstract：:The aims of the present study were to determine whether nerves that contain nitric oxide synthase (NOS), calcitonin gene-related peptide (CGRP) or substance P (SP) are present in the human vagina and, if so, to determine the pattern of innervation relative to that of other neurotransmitters, particularly vasoactive in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:Wallerian degeneration and dying-back pathology are two well-known cellular pathways capable of regulating the breakdown and loss of axonal and synaptic compartments of neurons in vivo. However, the underlying mechanisms and molecular triggers of these pathways remain elusive. Here, we show that loss of translation el...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.01007.x
更新日期：2008-12-01 00:00:00
abstract：:The permeability of the skin of fetal rats between 14 and 21 days of intrauterine life was investigated by injecting lanthanum nitrate solution subepidermally and by exposing the external surface of other fetuses to the same solution. Up to the age of 18 days, the epidermis was freely permeable from the basal surface ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:Fibre type composition in the soleus muscle was studied in second generation male and female Sprague-Dawley rats bred at 460 Torr (hypobaric hypoxia). In control male and female rats (bred at sea level atmospheric pressure) the percentage of slow twitch oxidative (SO) fibres increased, and the percentage of fast twitc...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of the internal elastic membrane. Dissociation of the inner media may also be involved. The persistent ductus can be recogniz...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-06-01 00:00:00
abstract：:The penile bone and anterior process were made anorganic for scanning electron microscopy. The mature bone has a basal bulb and a long, cylindrical shaft bevelled at its tip to fit under a matching surface on the anterior process, giving rise to a bevelled 'suture'. A rough, resting, Sharpey-fibre bone surface covers ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:The ligamentous attachments of the lumbar spinous processes were studied by dissection and histological examination in seven dogs, three cats and six baboons. Unlike man, the lumbar spines of these animals do not possess a supraspinous ligament and there is no decussation of the erector spinae tendons in the lower lum...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:Two or three or sometimes more fine intracavernous branches were traced from the ophthalmic nerve using serial section reconstruction and induced nerve degeneration. They joined the cavernous plexus and were distributed forward with autonomic nerves to the adventitia of the internal carotid artery, emerging from the s...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-12-01 00:00:00
abstract：:In the enameloid matrix a large number of tubular vesicles appeared around the odontoblast processes at the stage of enameloid matrix formation. The tubular vesicles were limited by unit membrane and the membrane often seemed to connect with that of the odontoblast processes. The tubular vesicles probably originated f...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:The primary aim of this study is to broadly evaluate the relationship between cursoriality (i.e. anatomical and physiological specialization for running) and limb bone morphology in lagomorphs. Relative to most previous studies of cursoriality, our focus on a size-restricted, taxonomically narrow group of mammals perm...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12220
更新日期：2014-10-01 00:00:00
abstract：:Two arteries connect the anterior branch of the middle meningeal artery to the lacrimal artery. One vessel, the sphenoidal artery, passes through the superior orbital fissure. The other vessel, the meningolacrimal artery, passes through the cranio-orbital foramen. An analysis of data derived from embryology, comparati...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:The mean fibre areas of samples from m. semitendinosus, m. diaphragma and m. pectoralis transversus of thoroughbred horses and greyhounds have been compared with those in similar samples from other members of their species. Athletes (greyhounds and thoroughbreds) have larger fibres in the semitendinosus and diaphragm ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-10-01 00:00:00
abstract：:The neuromuscular junction (NMJ) is the highly specialised peripheral synapse formed between lower motor neuron terminals and muscle fibres. Post-synaptic acetylcholine receptors (AChRs), which are found in high density in the muscle membrane, bind to acetylcholine released into the synaptic cleft of the NMJ, thereby ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13228
更新日期：2020-10-01 00:00:00
abstract：:At the time of blastocyst implantation the uterine spiral arteries have already undergone morphological changes in the absence of any extravillous trophoblast invasion. Only 2 weeks after implantation, extravillous trophoblast cells develop and come into first contact with decidual tissues. Invading through the decidu...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2008.01036.x
更新日期：2009-07-01 00:00:00
abstract：:The evolution of animal morphology can be understood as a series of changes in developmental programs. Among vertebrates, some developmental stages are conserved across species, representing particular developmental constraints. One of the most conserved stages is the vertebrate pharyngula, in which similar embryonic ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2005.00483.x
更新日期：2005-11-01 00:00:00
abstract：:A quantitative, postmortem study of 36 human inferior alveolar nerves is described. The total myelinated fibre count (TMFC) of nerves was not related to sex or age of the subjects but significant positive correlations were found between TMFC and subject body weight in both dentate (r = 0.616) and edentulous (r = 0.676...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:M. semitendinosus and m. trapezius (portion) were removed from eight miniature pigs ranging from 21 to 160 days of age and eight age-control as well as eight weight-control commercial Large White pigs. Complete transverse frozen sections were obtained for each muscle sample and stained for various enzyme activities in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
