Abstract：
:The lymphoid tissues of the red-tailed phascogale (Phascogale calura) were examined using histological and immunohistochemical techniques. The distribution of immune cells in the tissue beds was documented using antibodies to surface markers CD3 and an MHC Class II antigen (equivalent to HLA DRII). Spleen, gut-associated lymphoid tissues (GALT), lung, bronchus-associated lymphoid tissue (BALT) and liver were examined. The spleen had defined areas of red and white pulp, with follicles containing tingible-bodied macrophages. Anti-CD3 and anti-HLA DRII antibodies revealed the presence of T cells in areas of white pulp and around the peri-arterial lymphatic sheaths. GALT and BALT were detected and appeared as scattered areas of lymphocytes in the tissues beds. This is the first study to report on the lymphoid tissues of this endangered species of marsupial and the first report of the capacity of anti-human antibodies to a surface MHC molecule to react with Dasyurid cells.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Old JM,Carman RL,Fry G,Deane EMdoi
10.1111/j.1469-7580.2006.00530.xkeywords:
subject
Has Abstractpub_date
2006-03-01 00:00:00pages
381-7issue
3eissn
0021-8782issn
1469-7580pii
JOA530journal_volume
208pub_type
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