Abstract：
:Interneurons are an integral part of cortical neuronal circuits. During the past decade, numerous studies have shown that these cells, unlike their pyramidal counterparts that are derived from the neuroepithelium along the lumen of the lateral ventricles, are generated in the ganglionic eminences in the subpallium. They use tangential migratory paths to reach the cortex, guided by intrinsic and extrinsic cues. Evidence is now emerging which suggests that the family of Slit proteins, acting through Robo receptors, play a role not only in axon guidance in the developing forebrain, but also as guiding signals in the migration of cortical interneurons. Here we describe the patterns of expression of Slit and Robo at different stages of forebrain development and review the evidence in support of their role in cortical interneuron migration. Slit-Robo signal transduction mechanisms are also important during normal development in a number of systems in the body and in disease states, making them potential therapeutic targets for the treatment of neurological disorders and certain types of cancer.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Andrews WD,Barber M,Parnavelas JGdoi
10.1111/j.1469-7580.2007.00750.xsubject
Has Abstractpub_date
2007-08-01 00:00:00pages
188-98issue
2eissn
0021-8782issn
1469-7580pii
JOA750journal_volume
211pub_type
杂志文章,评审abstract：:The testicular capsule was studied histologically, morphometrically, ultrastructurally and immunohistochemically in the Japanese quail, domestic fowl, turkey and duck (all members of the Galloanserae). The testicular capsule was, relative to mammals, thin, being 81.5 +/- 13.7 microm in the quail, 91.7 +/- 6.2 microm i...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00726.x
更新日期：2007-06-01 00:00:00
abstract：:The mitotic response to wounding was examined in ulcers resulting from the excision of small pieces of rectal mucous membrane in two groups of guinea-pigs. One group was wounded at 09.00 hours and a second group at 21.00 hours. Mitotic counts were carried out in the glandular epithelium at the ulcer edges at 2 hourly ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:The present report describes quantitative studies of mitochondria from stratified squamous epithelial cells from hamster cheek pouch mucosa in differentiating compartments. Mucosa was processed for electron microscopy and, using strict sampling procedures, electron micrographs of epithelium from defined basal, spinous...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-06-01 00:00:00
abstract：:Classic anatomical methods have failed to determine the precise location, origin and nature of nerve fibres in the inferior hypogastric plexus (IHP). The purpose of this study was to identify the location and nature (adrenergic and/or cholinergic) of IHP nerve fibres and to provide a three-dimensional (3D) representat...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01071.x
更新日期：2009-05-01 00:00:00
abstract：:The distributing of vimentin and cytokeratin intermediate filaments within the cells of the dental follicle and developing periodontal ligament is described during eruption of the rat 1st molar tooth. Alcohol-fixed tissues from animals ranging from neonates to 12 wk old were cryosectioned, immunolabelled with monoclon...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:Many studies have demonstrated the association between facet tropism and disc herniation in the lumbar spine. Some of them found that lumbar disc herniation was on the side of the more sagittal facet joint interface. However, little is understood about the association of facet tropism with disc herniation in the cervi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13151
更新日期：2020-05-01 00:00:00
abstract：:Alveolar macrophages were isolated from the lungs of hamsters by lavage and centrifugation. The harvesting procedure yielded about 5.2 X 10(6) cells per animal and the majority of these cells were viable as assessed by a Trypan blue exclusion test. Monolayers of macrophages were labelled with a series of FITC-conjugat...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:We previously identified a pericellular matrix keratan sulphate/chondroitin sulphate proteoglycan present on the surface of human embryonal carcinoma stem cells, cells whose differentiation mimics early development. Antibodies reactive with various epitopes on this molecule define a cluster of differentiation markers ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2002.00034.x
更新日期：2002-03-01 00:00:00
abstract：:Little is known about the embryonic development and variation of the chondrocranium in Crocodylia and there are no works on any Caiman species. Due to the importance of cranial features in the systematics of this clade, investigating the development of the skull in embryonic stages is essential. In this study, we pres...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12968
更新日期：2019-06-01 00:00:00
abstract：:The distribution of mRNAs and antigens of tissue type (t) and urokinase type (u) plasminogen activators (PA) plus their corresponding inhibitors, type-1 (PAI-1) and type-2 (PAI-2) were studied in human and rhesus monkey placentae by in situ hybridisation and immunocytochemistry. Specific monkey cRNA and antibodies aga...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19420183.x
更新日期：1999-02-01 00:00:00
abstract：:The arteries of the skin have been postulated to form a profound plexus at the dermal/hypodermal junction and a superficial plexus in the papillary dermis. Our article aims to rebut this concept and to provide an alternative description of the arrangement of the dermal arteries. Employing a novel technique, we produce...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12113
更新日期：2013-12-01 00:00:00
abstract：:The translocation of mitochondria towards the primitive inner segment of the cones in the tree shrew Tupaia belangeri was investigated by transmission electron microscopy. Throughout ontogeny the migrating mitochondria were codistributed with cytoplasmic microtubules which were preserved after the application of conve...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Peripheral sensory and autonomic neurons are known to possess insulin receptors. These have been considered to be of the peripheral type, i.e. similar to those of hepatic and fat cells rather than of the brain type which show dual specificity for both insulin and insulin-like growth factor (IGF-1). We have examined th...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1997.19130431.x
更新日期：1997-10-01 00:00:00
abstract：:The ultrastructure of the tammar placenta was studied throughout pregnancy. The uterine epithelium grows from a columnar to an enlarged, undulating epithelium between early gestation and mid-gestation when the shell coat that surrounds the marsupial conceptus ruptures. Trophectoderm and uterine epithelium do not form ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2002.00084.x
更新日期：2002-08-01 00:00:00
abstract：:The development of sensory innervation in long bones was investigated in rat tibia in fetuses on gestational days (GD) 16-21 and in neonates and juvenile individuals on postnatal days (PD) 1-28. A double immunostaining method was applied to study the co-localization of the neuronal growth marker growth-associated prot...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2005.00434.x
更新日期：2005-08-01 00:00:00
abstract：:The architecture of the fibres in the sciatic nerve of the dog has been analysed by following the degeneration of fibres resulting from division of the individual spinal nerves which contribute to the sciatic nerve. A pattern has been demonstrated which varies in part with the size of the contribution to the sciatic n...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-10-01 00:00:00
abstract：:Ceratopsidae represents a group of quadrupedal herbivorous dinosaurs that inhabited western North America and eastern Asia during the Late Cretaceous. Although horns and frills of the cranium are highly variable across species, the lower jaw historically has been considered to be relatively conservative in morphology....
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12374
更新日期：2015-11-01 00:00:00
abstract：:A monoclonal antibody SBU-3 raised against an antigen expressed by the binucleate cells in the trophoblast of the sheep placentome crossreacts with an antigen expressed by binucleate cells in the placenta of the deer and the cow. This monoclonal antibody has been used to study the distribution of this subpopulation of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:Kokartus honorarius from the Middle Jurassic (Bathonian) of Kyrgyzstan is one of the oldest salamanders in the fossil record, characterized by a mixture of plesiomorphic morphological features and characters shared with crown-group salamanders. Here we present a detailed histological analysis of its long bones. The an...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12281
更新日期：2015-04-01 00:00:00
abstract：:The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of the internal elastic membrane. Dissociation of the inner media may also be involved. The persistent ductus can be recogniz...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-06-01 00:00:00
abstract：:The behavioral differences in muscle use are related to the fiber type composition of the muscles among other variables. The aim of this study was to examine the degree of heterogeneity in the fiber type composition in the rat temporalis muscle. The temporalis muscle was taken from 10-week-old Wistar strain male rats ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00990.x
更新日期：2008-12-01 00:00:00
abstract：:The entire lengths of central and peripheral myelin sheaths on the same ventral motoneuron axons of young rats were studied during the rapid early phase of myelination which occurs during the first 2 weeks after birth. Sheath thickness varied along central internodes at all ages, though this variation was less in the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:In the infant the region lateral to the sella turcica which is traditionally termed the 'cavernous sinus' is composed of 3 individual compartments. The aim of this study was to demonstrate a similar compartmentation of the adult cavernous sinus and to identify and quantify the adipose bodies which are located within t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2000.19740681.x
更新日期：2000-11-01 00:00:00
abstract：:Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophage...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:The neurotropic effect of the distal stump of transected sciatic nerve on regenerating axons emerging from the proximal stump was investigated in rats by the coculture of excised neonatal dorsal root ganglia and segments of degenerated and nondegenerated sciatic nerves. In all cultures, neurites from the ganglion exte...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:The distribution of neurons expressing NADPH diaphorase activity was examined histochemically in whole mount preparations of the neonatal guinea pig urinary bladder. NADPH diaphorase positive neurons were abundant in the intramural ganglia in both the detrusor and trigone regions of the bladder. Labelled nerve fibres ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:The scapholunate interosseous ligament (SLIL) connects the scaphoid and lunate bones and plays a crucial role in carpal kinematics. Its rupture leads to carpal instability and impairment of radiocarpal joint function. As the ligament is one of the first structures affected in rheumatoid arthritis, we conducted an immu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00552.x
更新日期：2006-06-01 00:00:00
abstract：:Elastic fibres, which are intimately associated with collagen, a major component of the urethra, have been assumed to contribute to the resting urethral closure pressure. The Miller stain for elastin was used to demonstrate elastic fibres in cryostat sections of guinea pig bladder base, vesicourethral junction (VUJ) a...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19530447.x
更新日期：1999-10-01 00:00:00
abstract：:The distance of the neuromuscular gap was measured in a chicken smooth muscle, m. retractor phalli cranialis (MRPC). For the identification of active neuromuscular contacts, acetylcholinesterase (AChE) was stained according to Tago's modification of the Karnovsky and Roots' method. Thirty two out of 500 muscle cells w...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:The present paper reports the results of the first investigation of the semicircular canals in a living, small animal by means of high spatial resolution magnetic resonance imaging. This procedure is noninvasive and allows identification of the endolymphatic and perilymphatic spaces yielding a morphology quite consist...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
