Abstract：
:The neurotropic effect of the distal stump of transected sciatic nerve on regenerating axons emerging from the proximal stump was investigated in rats by the coculture of excised neonatal dorsal root ganglia and segments of degenerated and nondegenerated sciatic nerves. In all cultures, neurites from the ganglion extended directly towards the degenerated distal stump and not towards the undegenerated nerve segment. Analysis of the supernatants of nerve homogenates by native polyacrylamide gel electrophoresis demonstrated that 250 and 18 kDa proteins were upregulated in the degenerated distal stumps and that 89, 67 and 65 kDa proteins were expressed by these stumps but not by normal nerve. Placement of the individual protein strips, cut from the gels, in dissociated cultures of dorsal root ganglion cells showed that the 89 and 18 kDa strips possessed strong neurotropic activity. Neurons survived selectively on these strips and outgrowing neurites elongated on the strips, parallel to the direction of the band. When explanted dorsal root ganglia were cultured along with the strips, outgrowing neurites extended selectively towards those containing the 89 and 18 kDa bands. It is concluded that these bands contain chemotropic substances, the nature of which requires further investigation.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Gu X,Thomas PK,King RHsubject
Has Abstractpub_date
1995-02-01 00:00:00pages
153-63eissn
0021-8782issn
1469-7580journal_volume
186 ( Pt 1)pub_type
杂志文章abstract：:Darwin's finches are a model system in ecological and evolutionary research, but surprisingly little is known about their skull morphology and development. Indeed, only the early beak development and external variation in adult beak shape has been studied. Understanding the development of the skull from embryo up to t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01388.x
更新日期：2011-08-01 00:00:00
abstract：:The distributing of vimentin and cytokeratin intermediate filaments within the cells of the dental follicle and developing periodontal ligament is described during eruption of the rat 1st molar tooth. Alcohol-fixed tissues from animals ranging from neonates to 12 wk old were cryosectioned, immunolabelled with monoclon...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:The epithalamus is a major subdivision of the diencephalon constituted by the habenular nuclei and pineal complex. Structural asymmetries in this region are widespread amongst vertebrates and involve differences in size. neuronal organisation, neurochemistry and connectivity. In species that possess a photoreceptive p...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.2001.19910063.x
更新日期：2001-07-01 00:00:00
abstract：:It has been shown that gibbons are able to brachiate with very low mechanical costs. The conversion of muscle activity into smooth, purposeful movement of the limb depends on the morphometry of muscles and their mechanical action on the skeleton. Despite the gibbon's reputation for excellence in brachiation, little in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01109.x
更新日期：2009-09-01 00:00:00
abstract：:The effects of varying periods of general protein-calorie undernutrition during early life on Purkinje cells in the cerebellum of the rat were examined. In Experiment 1, animals were undernourished from d 18 of gestation until either d 30 or d 60 of postnatal age, followed in some cases by a period of nutritional reha...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Clinical research on the deposition of inhaled substances (e.g. inhaled medications, airborne contaminants, fumes) in the lungs necessitates anatomical models of the airways. Current conducting airway models lack three-dimensional (3D) reality as little information is available in the literature on the distribution of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.0021-8782.2001.00018.x
更新日期：2002-02-01 00:00:00
abstract：:The entire lengths of central and peripheral myelin sheaths on the same ventral motoneuron axons of young rats were studied during the rapid early phase of myelination which occurs during the first 2 weeks after birth. Sheath thickness varied along central internodes at all ages, though this variation was less in the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:The sheep is a commonly used animal model for human lumbar spine surgery, but only in vitro investigations comparing the human and ovine spine exist. Spinal musculature has previously not been compared between man and sheep. This additional knowledge could further indicate to what extent these species are biomechanica...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12354
更新日期：2015-10-01 00:00:00
abstract：:Keratinocytes, in response to irritants, secrete pro-inflammatory mediators which recruit and activate immune and mesenchymal cells, including fibroblasts, to repair the skin. Fibroblasts respond by synthesising collagen and promoting the crosslinking extracellular matrix (ECM). We recently showed that the deletion of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12442
更新日期：2016-05-01 00:00:00
abstract：:Two arteries connect the anterior branch of the middle meningeal artery to the lacrimal artery. One vessel, the sphenoidal artery, passes through the superior orbital fissure. The other vessel, the meningolacrimal artery, passes through the cranio-orbital foramen. An analysis of data derived from embryology, comparati...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:Decline of tactile sensation associated with ageing depends on modifications in skin and both central and peripheral nervous systems. At present, age-related changes in the periphery of the somatosensory system, particularly concerning the effects on mechanoreceptors, remain unknown. Here we used immunohistochemistry ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12983
更新日期：2019-06-01 00:00:00
abstract：:This study describes the degenerative changes of the axon terminals making synaptic contacts with the neurons in the submucous ganglia of guinea pig small and large intestines following left or right cervical vagotomy. There were no noticeable ultrastructural changes 1 d after the operation. Beginning at the 3rd posto...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Cellullar deficits are replenished within the central nervous system (CNS) by progenitors to maintain integrity and recover function after injury. NG2 proteoglycan-expressing progenitors replenish oligodendrocyte populations, but the nature of NG2 proteoglycan may not indicate a restricted population of progenitors. A...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2005.00480.x
更新日期：2005-12-01 00:00:00
abstract：:Mechanisms of lubrication of human synovial joints have been analysed in terms of the operating conditions of the joint, the synovial fluid and articular cartilage. In the hip and knee during a walking cycle the load may rise up to four times body weight. In the knee on dropping one metre the load may go up to 25 time...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1976-02-01 00:00:00
abstract：:The blood supply to the cranial venae cavae on both sides and to the heart was studied macroscopically in 40 adult laboratory shrews (Suncus murinus) of both sexes injected either with Neoprene latex into the abdominal aorta (25 animals) or with Mercox into the left ventricle (15 animals). The 1st branch of the left s...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:Data are presented on the postnatal growth of the mouse bladder. Both bladder size (measured as surface area) and bladder wet weight increase steadily with age, respectively reaching 2.5 times and 4 times their newborn values by the age of ten weeks. Despite this growth, which may be due principally to non-urothelial ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:The type and number of cell contacts between fibroblasts were studied in three structurally distinct varieties of periodontal connective tissue in the rat mandible (periodontal ligament of the incisor, enamel-related connective tissue of the incisor and periodontal ligament of the molar). Three types of cell contact w...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-08-01 00:00:00
abstract：:The entire head and neck of a wild adult male Mongolian gazelle (Procapra gutturosa) was dissected with special reference to its enlarged larynx. Two additional adult male specimens taken from the wild were analysed by computer tomography. The sternomandibularis, omohyoideus, thyrohyoideus and hyoepiglotticus muscles ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00232.x
更新日期：2003-11-01 00:00:00
abstract：:The differentiation of granulated metrial gland (GMG) cells has been investigated during deciduomata formation in radiation-induced chimeric mice reconstituted with rat or mouse bone marrow. The extent of the decidual reaction was apparently normal in regions of the uterine horns shielded from the irradiation but was ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-12-01 00:00:00
abstract：:We present a simple and quick system for accurately scoring the developmental progress of mouse embryos harvested on embryonic day 14 (E14.5). Based solely on the external appearance of the maturing forelimb, we provide a convenient way to distinguish six developmental sub-stages. Using a variety of objective morphome...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12590
更新日期：2017-05-01 00:00:00
abstract：:In zoology it is well known that birds are characterized by the presence of feathers, and mammals by hairs. Another common point of view is that avian scales are directly related to reptilian scales. As a skin embryologist, I have been fascinated by the problem of regionalization of skin appendages in amniotes through...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2008.01041.x
更新日期：2009-04-01 00:00:00
abstract：:Since their discovery in different human tissues by Zimmermann in 1898, primary cilia have been found in the vast majority of cell types in vertebrates. Primary cilia are considered to be cellular antennae that occupy an ideal cellular location for the interpretation of information both from the environment and from o...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12360
更新日期：2015-10-01 00:00:00
abstract：:Despite the long-held assumption that olfaction plays a relatively minor role in the behavioral ecology of birds, crown-group avians exhibit marked phylogenetic variation in the size and form of the olfactory apparatus. As part of a larger effort to better understand the role of olfaction and olfactory tissues in the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13197
更新日期：2020-08-01 00:00:00
abstract：:This review describes the progress made in preparing Cochrane systematic reviews of randomized controlled trials for Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN) and the demyelinating neuropathies associated with paraproteins. The di...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.2002.00041.x
更新日期：2002-04-01 00:00:00
abstract：:The anatomy of the hypothalamus includes many nuclei and a complex network of neurocircuits. In this context, some hypothalamic nuclei reside closer to the blood-brain barrier, allowing communication with the peripheral organs through some molecules, such as leptin. Leptin is considered the main adipokine for energy h...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13342
更新日期：2020-10-22 00:00:00
abstract：:The sensory and motor innervation of a sample of 202 muscle spindles from the dorsolateral tail muscles of eight cats were studied by silver and gold staining techniques. The range of diameters of Group Ia afferent nerve fibres to primary (P) sensory endings was 2.0-14.0 micron with a peak at 8.5 micron. The range of ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The fine structure of the elastic cartilage of the pinna has been examined in young rabbits aged from 1 day to 1108 days. Changes associated with growth and development are related not only to age but also to the actual situation in the pinna. In the midline, progressive changes are seen from the tip to the base. The ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:Assessment of global endocranial morphology and regional neuroanatomical changes in early hominins is critical for the reconstruction of evolutionary trajectories of cerebral regions in the human lineage. Early evidence of cortical reorganization in specific local areas (e.g. visual cortex, inferior frontal gyrus) is ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12745
更新日期：2018-02-01 00:00:00
abstract：:Early hominins formed large and thick-enamelled cheek-teeth within relatively short growth periods as compared with modern humans. To understand better the developmental basis of this process, we measured daily enamel increments, or cross striations, in 17 molars of Plio-Pleistocene hominins representing seven differe...
journal_title：Journal of anatomy
pub_type： 历史文章,杂志文章
doi：10.1111/j.1469-7580.2008.00938.x
更新日期：2008-08-01 00:00:00
abstract：:The mammalian cochlea is a remarkable sensory organ, capable of perceiving sound over a range of 10(12) in pressure, and discriminating both infrasonic and ultrasonic frequencies in different species. The sensory hair cells of the mammalian cochlea are exquisitely sensitive, responding to atomic-level deflections at s...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/joa.12314
更新日期：2016-02-01 00:00:00
