Abstract:
:The mammalian cochlea is a remarkable sensory organ, capable of perceiving sound over a range of 10(12) in pressure, and discriminating both infrasonic and ultrasonic frequencies in different species. The sensory hair cells of the mammalian cochlea are exquisitely sensitive, responding to atomic-level deflections at speeds on the order of tens of microseconds. The number and placement of hair cells are precisely determined during inner ear development, and a large number of developmental processes sculpt the shape, size and morphology of these cells along the length of the cochlear duct to make them optimally responsive to different sound frequencies. In this review, we briefly discuss the evolutionary origins of the mammalian cochlea, and then describe the successive developmental processes that lead to its induction, cell cycle exit, cellular patterning and the establishment of topologically distinct frequency responses along its length.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Basch ML,Brown RM 2nd,Jen HI,Groves AKdoi
10.1111/joa.12314subject
Has Abstractpub_date
2016-02-01 00:00:00pages
233-54issue
2eissn
0021-8782issn
1469-7580journal_volume
228pub_type
杂志文章,评审abstract::Due to conflicting data from previous studies a new methodological approach to evaluate heel pad stiffness and soft tissue deformation has been developed. The purpose of this study was to compare heel pad (HP) stiffness in both limbs between males and females during a dynamic unloading and loading activity. Ten males ...
journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
pub_type: 杂志文章
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
pub_type: 杂志文章
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
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journal_title:Journal of anatomy
pub_type: 杂志文章
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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更新日期:1975-02-01 00:00:00
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
pub_type: 杂志文章
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
pub_type: 杂志文章
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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journal_title:Journal of anatomy
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