An ultrastructural study of the submucous plexus of guinea pig intestine after unilateral vagotomy.


:This study describes the degenerative changes of the axon terminals making synaptic contacts with the neurons in the submucous ganglia of guinea pig small and large intestines following left or right cervical vagotomy. There were no noticeable ultrastructural changes 1 d after the operation. Beginning at the 3rd postoperative day for the small intestines and the 5th day for the large intestines, some of the axon terminals presynaptic to the submucous neurons displayed different stages of degeneration. The most obvious feature of the degenerating terminals was the swelling and vacuolation of mitochondria with disrupted cristae; another change was the clumping of synaptic vesicles. In the animals killed 7 d after vagotomy, besides the above changes, the degenerating axon terminals also showed an accumulation of a variable amount of glycogen-like particles. The changes were most severe in the guinea pigs killed on the 10th postoperative day. The synaptic vesicles in some degenerating terminals were depleted. There were occasional degenerating nerve cell bodies in the submucous ganglia in the period studied. A variable number of lamellated bodies were found in some of the submucous neurons of 10 and 15 d postoperative animals. By 30 d after vagotomy, all the terminals presynaptic to the submucous neurons appeared normal. There was no significant difference in the total number of axon terminals between 10 d and 30 d after operation (P > 0.05). This suggests that either there had been successful reinnervation or new synaptic contacts had been established by sprouting from the unoperated vagus or other intrinsic neurons. The present quantitative studies also showed that the number of degenerating axon terminals in the submucous ganglia of duodenum after left vagotomy was higher than right vagotomy (P < 0.05). This feature was particularly evident in animals killed 10 d after the operation. The larger number of degenerating terminals in the submucous ganglia of duodenum after left vagotomy suggests that the presynaptic axon terminals in the submucous ganglia of different gut regions are not evenly distributed. Finally, the present study showed that the degenerative changes in the small intestine preceded the large intestine.


J Anat


Journal of anatomy


Wang XY,Wong WC,Ling EA


Has Abstract


1995-12-01 00:00:00








187 ( Pt 3)


  • A quantitative electron microscopic study of myelination in the anterior limb of the anterior commissure of the mouse brain.

    abstract::An electron microscopic study of myelination was carried out in the anterior limb of the anterior commissure of the mouse brain. The total number of axons increased from 48 700 at 17 days post-conception to 286 500 at 11 days postnatum. The first evidence of myelination was the presence of a few promyelin fibres at 8 ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Sturrock RR

    更新日期:1975-02-01 00:00:00

  • Calcaneocuboid joint and stability of the longitudinal arch of the foot at high and low gear push off.

    abstract::The calcaneocuboid joint was studied in ligamentous specimens of ten human feet, and in skeletons of two gorillas (Gorilla gorilla beringei), six chimpanzees (Pan troglodytes), three orangutans (Pongo pygmaeus) and 25 human feet. The movement of the transverse tarsal joint was further studied in a living foot on a wal...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Bojsen-Møller F

    更新日期:1979-08-01 00:00:00

  • Feasibility, accuracy and safety of a percutaneous fine-needle biopsy technique to obtain qualitative muscle samples of the lumbar multifidus and erector spinae muscle in persons with low back pain.

    abstract::The lumbar muscular system, in particular the lumbar multifidus muscle (LM) and the erector spinae muscle (ES), plays an important role in stabilizing and mobilizing the lumbar spine. Based on the topography, the lumbar paraspinal muscles can be classified into local and global muscles. LM is part of the local system,...

    journal_title:Journal of anatomy

    pub_type: 临床试验,杂志文章


    authors: Agten A,Verbrugghe J,Stevens S,Boomgaert L,O Eijnde B,Timmermans A,Vandenabeele F

    更新日期:2018-10-01 00:00:00

  • Evaluation of pulmonary volumetric morphometry at the light and electron microscopy level in several species of passerine birds.

    abstract::The lungs of 3 small passerine species, having similar body mass but different diurnal activity patterns, were analysed morphometrically to assess the relationship between diurnal activity and pulmonary volumetry at the light and electron microscope levels. The percentage volumes of the major lung and exchange tissue ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Vitali SD,Richardson KC

    更新日期:1998-11-01 00:00:00

  • Aspects of PET imaging relevant to the assessment of striatal transplantation in Huntington's disease.

    abstract::Proper assessment of outcome in clinical trials of neural transplantation requires both biochemical and imaging indices of graft survival, and behavioural and physiological indices of graft function. For transplantation in Huntington's disease, a variety of ligands that are selective for striatal degeneration and graf...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审


    authors: Besret L,Kendall AL,Dunnett SB

    更新日期:2000-05-01 00:00:00

  • The thalamic projection to the sensory neocortex of the porpoise, Phocoena phocoena.

    abstract::Retrograde tracers were injected in various parts of the neocortex of the porpoise (Phocoena phocoena). Labelled thalamic neurons were plotted in three-dimensional reconstructions. The lateral geniculate nucleus projects to the visually excitable part of the lateral gyrus. Ventral parts of the medial geniculate nucleu...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Revishchin AV,Garey LJ

    更新日期:1990-04-01 00:00:00

  • Assessing the effectiveness of 30% sodium chloride aqueous solution for the preservation of fixed anatomical specimens: a 5-year follow-up study.

    abstract::Anatomical specimens used in human or veterinary anatomy laboratories are usually prepared with formaldehyde (a cancerous and teratogenic substance), glycerin (an expensive and viscous fluid), or ethanol (which is flammable). This research aimed to verify the viability of an aqueous 30% sodium chloride solution for pr...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: de Oliveira FS

    更新日期:2014-07-01 00:00:00

  • Appraising the methodological quality of cadaveric studies: validation of the QUACS scale.

    abstract::Although systematic reviews are conducted in the field of anatomical research, no instruments exist for the assessment of study quality. Thus, our objective was to develop a valid tool that reliably assesses the methodological quality of observational cadaveric studies. The QUACS scale (QUality Appraisal for Cadaveric...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Wilke J,Krause F,Niederer D,Engeroff T,Nürnberger F,Vogt L,Banzer W

    更新日期:2015-05-01 00:00:00

  • Towards understanding the dose and timing effect of hydrocortisone treatment on the scleral ossicle system within the chicken eye.

    abstract::Previous work, almost four decades ago, showed that hydrocortisone (HC) treatment reduces the number of skeletogenic condensations that give rise to the scleral ossicles in the chicken eye. The scleral ossicles are a ring of overlapping intramembranous bones, the sclerotic ring, and are present in most reptiles, inclu...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Hammer CL,Franz-Odendaal TA

    更新日期:2018-02-01 00:00:00

  • Non-myelinated nerve fibres and their terminals in the sub-odontoblastic plexus of the feline dental pulp.

    abstract::Serial thin sections of the coronal dental pulp of the cat's canine tooth were cut. Parts of the sub-odontoblastic neural plexus were photographed from 100 of the sections. The plexus consists of many slender, predominantly unmyelinated nerve fibres. Many axons are incompletely sheathed by their Schwann cell. Some axo...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Holland GR

    更新日期:1980-05-01 00:00:00

  • The development of Schmidt-Lanterman incisures: an electron microscope study.

    abstract::The development of Schmidt-Lanterman incisures was investigated in the rat sural nerve during an active phase of postnatal myelination (5-21 days post partum). Two distinct populations of incisures were recognised and the following nomenclature for their developmental stages is proposed. Primary incisures which appear...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Small JR,Ghabriel MN,Allt G

    更新日期:1987-02-01 00:00:00

  • Musculoskeletal anatomy of the pelvic fin of Polypterus: implications for phylogenetic distribution and homology of pre- and postaxial pelvic appendicular muscles.

    abstract::As a member of the most basal clade of extant ray-finned fishes (actinopterygians) and of one of the most basal clades of osteichthyans (bony fishes + tetrapods), Polypterus can provide insights into the ancestral anatomy of both ray-finned and lobe-finned fishes, including those that gave rise to tetrapods. The pecto...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Molnar JL,Johnston PS,Esteve-Altava B,Diogo R

    更新日期:2017-04-01 00:00:00

  • Corticofugal axons from adjacent 'barrel' columns of rat somatosensory cortex: cortical and thalamic terminal patterns.

    abstract::The cortical representations of the vibrissae of the rat form a matrix in which each whisker has its own area of cortex, called a 'barrel'. The afferent pathways from the periphery travel first to the trigeminal nuclei and thence via the ventroposteromedial thalamus (VPM) to the cortical barrels have been described in...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Wright AK,Norrie L,Arbuthnott GW

    更新日期:2000-04-01 00:00:00

  • Excitotoxic damage to white matter.

    abstract::Glutamate kills neurons by excitotoxicity, which is caused by sustained activation of glutamate receptors. In recent years, it has been shown that glutamate can also be toxic to white matter oligodendrocytes and to myelin by this mechanism. In particular, glutamate receptor-mediated injury to these cells can be trigge...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审


    authors: Matute C,Alberdi E,Domercq M,Sánchez-Gómez MV,Pérez-Samartín A,Rodríguez-Antigüedad A,Pérez-Cerdá F

    更新日期:2007-06-01 00:00:00

  • Variation with age in the labelling of amoeboid microglial cells in rats following intraperitoneal or intravenous injection of a fluorescent dye.

    abstract::Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Xu J,Kaur C,Ling EA

    更新日期:1993-02-01 00:00:00

  • Three-dimensional MRI perfusion maps: a step beyond volumetric analysis in mental disorders.

    abstract::A new type of magnetic resonance imaging analysis, based on fusion of three-dimensional reconstructions of time-to-peak parametric maps and high-resolution T1-weighted images, is proposed in order to evaluate the perfusion of selected volumes of interest. Because in recent years a wealth of data have suggested the cru...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Fabene PF,Farace P,Brambilla P,Andreone N,Cerini R,Pelizza L,Versace A,Rambaldelli G,Birbaumer N,Tansella M,Sbarbati A

    更新日期:2007-01-01 00:00:00

  • The joints of the evolving foot. Part III. The fossil evidence.

    abstract::The fossil record supports the conclusions derived from the study of extant species that the Primates evolved a unique suite of characters in the articulations of the foot. The tarsal bones of African Miocene apes show specializations characteristic of hominoid evolution and provide reasonable precursors for the morph...

    journal_title:Journal of anatomy

    pub_type: 历史文章,杂志文章


    authors: Lewis OJ

    更新日期:1980-09-01 00:00:00

  • Revisiting the infracardiac bursa using multimodal methods: topographic anatomy for surgery of the esophagogastric junction.

    abstract::In embryology, the infracardiac bursa (ICB) is a well-known derivative separated from the omental bursa. During surgeries around the esophagogastric junction (EGJ), surgeons often encounter a closed space considered to be equivalent to the ICB, but the macroscopic anatomy in adults is hardly known. This study aimed to...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Nakamura T,Shinohara H,Okada T,Hisamori S,Tsunoda S,Obama K,Kurahashi Y,Takai A,Shimokawa T,Matsuda S,Makishima H,Takakuwa T,Yamada S,Sakai Y

    更新日期:2019-07-01 00:00:00

  • Cortical bone development under the growth plate is regulated by mechanical load transfer.

    abstract::Longitudinal growth of long bones takes place at the growth plates. The growth plate produces new bone trabeculae, which are later resorbed or merged into the cortical shell. This process implies transition of trabecular metaphyseal sections into diaphyseal sections. We hypothesize that the development of cortical bon...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Tanck E,Hannink G,Ruimerman R,Buma P,Burger EH,Huiskes R

    更新日期:2006-01-01 00:00:00

  • Investigating the effect of hypoxic culture on the endothelial differentiation of human amniotic fluid-derived stem cells.

    abstract::Amniotic fluid-derived stem cells (AFSCs) are a unique stem cell source that may have great potential for use in tissue engineering (TE) due to their pluripotentiality. AFSCs have previously shown angiogenic potential and may present an alternative cell source for endothelial-like cells that could be used in range of ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Lloyd-Griffith C,Duffy GP,O'Brien FJ

    更新日期:2015-12-01 00:00:00

  • NADPH diaphorase and nitric oxide synthase are expressed by the majority of intramural neurons in the neonatal guinea pig urinary bladder.

    abstract::The distribution of neurons expressing NADPH diaphorase activity was examined histochemically in whole mount preparations of the neonatal guinea pig urinary bladder. NADPH diaphorase positive neurons were abundant in the intramural ganglia in both the detrusor and trigone regions of the bladder. Labelled nerve fibres ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Saffrey MJ,Hassall CJ,Moules EW,Burnstock G

    更新日期:1994-12-01 00:00:00

  • The impact of obesity on skeletal muscle architecture in untrained young vs. old women.

    abstract::It is unknown whether loading of the lower limbs through additional storage of fat mass as evident in obesity would promote muscular adaptations similar to those seen with resistance exercise. It is also unclear whether ageing modulates any such adjustments. This study aimed to examine the relationships between adipos...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Tomlinson DJ,Erskine RM,Winwood K,Morse CI,Onambélé GL

    更新日期:2014-12-01 00:00:00

  • Biochemical properties of a keratan sulphate/chondroitin sulphate proteoglycan expressed in primate pluripotent stem cells.

    abstract::We previously identified a pericellular matrix keratan sulphate/chondroitin sulphate proteoglycan present on the surface of human embryonal carcinoma stem cells, cells whose differentiation mimics early development. Antibodies reactive with various epitopes on this molecule define a cluster of differentiation markers ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Cooper S,Bennett W,Andrade J,Reubinoff BE,Thomson J,Pera MF

    更新日期:2002-03-01 00:00:00

  • Tie-fibre structure and organization in the knee menisci.

    abstract::The collagenous structure of the knee menisci is integral to the mechanical integrity of the tissue and the knee joint. The tie-fibre structure of the tissue has largely been neglected, despite previous studies demonstrating its correlation with radial stiffness. This study has evaluated the structure of the tie-fibre...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Andrews SH,Rattner JB,Abusara Z,Adesida A,Shrive NG,Ronsky JL

    更新日期:2014-05-01 00:00:00

  • Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT).

    abstract::Following the discovery that the proto-oncogene protein kinase B (PKB) functions as a downstream element in signalling from phosphoinositide 3'-kinase (PI3-kinase) (Burgering & Coffer, 1995), PKB has been shown to mediate a diverse array of PI3-kinase dependent cellular responses. Most recently PKB-dependent phosphory...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审


    authors: Kops GJ,Burgering BM

    更新日期:2000-11-01 00:00:00

  • Oxygen as modulator of trophoblast invasion.

    abstract::At the time of blastocyst implantation the uterine spiral arteries have already undergone morphological changes in the absence of any extravillous trophoblast invasion. Only 2 weeks after implantation, extravillous trophoblast cells develop and come into first contact with decidual tissues. Invading through the decidu...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审


    authors: Huppertz B,Gauster M,Orendi K,König J,Moser G

    更新日期:2009-07-01 00:00:00

  • Coexistence of adrenergic and cholinergic nerves in the inferior hypogastric plexus: anatomical and immunohistochemical study with 3D reconstruction in human male fetus.

    abstract::Classic anatomical methods have failed to determine the precise location, origin and nature of nerve fibres in the inferior hypogastric plexus (IHP). The purpose of this study was to identify the location and nature (adrenergic and/or cholinergic) of IHP nerve fibres and to provide a three-dimensional (3D) representat...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Alsaid B,Bessede T,Karam I,Abd-Alsamad I,Uhl JF,Benoît G,Droupy S,Delmas V

    更新日期:2009-05-01 00:00:00

  • Quantitative description of the spatial arrangement of organelles in a polarised secretory epithelial cell: the salivary gland acinar cell.

    abstract::Previous quantitative descriptions of cellular ultrastructure have focused on spatial content (volume, surface area and number of organelles and membrane domains). It is possible to complement such descriptions by also quantifying spatial arrangements. Hitherto, applications of stereological methods for achieving this...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Mayhew TM

    更新日期:1999-02-01 00:00:00

  • Myology of the forelimb of Majungasaurus crenatissimus (Theropoda, Abelisauridae) and the morphological consequences of extreme limb reduction.

    abstract::Forelimb reduction occurred independently in multiple lineages of theropod dinosaurs. Although tyrannosaurs are renowned for their tiny, two-fingered forelimbs, the degree of their reduction in length is surpassed by abelisaurids, which possess an unusual morphology distinct from that of other theropods. The forelimbs...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Burch SH

    更新日期:2017-10-01 00:00:00

  • The internal cranial morphology of an armoured dinosaur Euoplocephalus corroborated by X-ray computed tomographic reconstruction.

    abstract::Internal cranial anatomy is a challenging area to study in fossilized skulls because of small sample sizes and varied post-mortem preservational alterations. This difficulty has led to the lack of correspondence between results obtained from direct osteological observation and from more indirect reconstruction methods...

    journal_title:Journal of anatomy

    pub_type: 杂志文章


    authors: Miyashita T,Arbour VM,Witmer LM,Currie PJ

    更新日期:2011-12-01 00:00:00