Abstract：
:This review describes the progress made in preparing Cochrane systematic reviews of randomized controlled trials for Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN) and the demyelinating neuropathies associated with paraproteins. The discovery of antibodies against myelin and axolemmal glycolipids and proteins has not yet replaced the clinicopathological classification on which treatment trials have been based. Systematic reviews have endorsed the equivalence of plasma exchange (PE) and intravenous immunoglobulin (IVIg) and the lack of efficacy of steroids in GBS. Systematic reviews have also endorsed the value of steroids, PE and IVIg in CIDP but randomized controlled trials have only shown benefit from IVIg in MMN. There is a paucity of evidence concerning the efficacy of treatments in paraproteinaemic demyelinating neuropathy apartment from small trials showing short-term benefit from PE or IVIg. There is a lack of good quality controlled trials of immunosuppressive agents in any of these conditions. As the number of treatment trials increases, Cochrane systematic reviews will be an increasingly valuable resource for summarizing the evidence from randomised controlled trials on which to base clinical practice. They already demonstrate major deficiencies in the existing evidence base.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Hughes RAdoi
10.1046/j.1469-7580.2002.00041.xkeywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
331-9issue
4eissn
0021-8782issn
1469-7580journal_volume
200pub_type
杂志文章,评审abstract：:As the uterus enlarges to accommodate the growing fetus during pregnancy, the cervix behaves essentially as a barrier. During ripening and delivery, it needs to become soft and distensible to allow dilation and the passage of the conceptus. As the transformations of the collagen-containing fibres are known to be essen...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00227.x
更新日期：2003-10-01 00:00:00
abstract：:The ultrastructure of 3 fibrocartilages is described at the insertion of the adult rat Achilles tendon. Enthesial fibrocartilage lies at the tendon-bone junction, sesamoid fibrocartilage in the deep surface of the tendon where it presses on the calcaneus, and periosteal fibrocartilage covers the opposing surface of th...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Interosseous sutures exhibit highly variable patterns of interdigitation and corrugation. Recent research has identified fundamental molecular mechanisms of suture formation, and computer models have been used to simulate suture morphogenesis. However, the role of bone strain in the development of complex sutures is l...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01386.x
更新日期：2011-08-01 00:00:00
abstract：:Apart from molecular data, nearly all the evidence used to study primate relationships comes from hard tissues. Here, we provide details of the first parsimony and Bayesian cladistic analyses of the order Primates based exclusively on muscle data. The most parsimonious tree obtained from the cladistic analysis of 166 ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01403.x
更新日期：2011-09-01 00:00:00
abstract：:Standard immunohistochemical methods were used to detect the presence of vimentin, cytokeratin 8, cytokeratin 18, macrophages and Langerhans cells in the human tonsillar epithelium in formalin-fixed and frozen tissue specimens. Vimentin detection was restricted to infiltrating cells of the lymphoid series, dendritic a...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19960663.x
更新日期：2001-12-01 00:00:00
abstract：:This paper reports on the development of a theoretical model to simulate the growth and repair of microdamage in bone. Unlike previous theories, which use simplified descriptions of damage, this approach models each individual microcrack explicitly, and also models the basic multicellular units (BMUs) that repair crac...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00194.x
更新日期：2003-08-01 00:00:00
abstract：:The effects of chronic neuromuscular inactivity on the phenotype and size of muscle fibres in a fast ankle extensor (medial gastrocnemius, MG) and a fast ankle flexor (tibialis anterior, TA) muscle of the rat hindlimb were determined. Inactivity was produced by spinal cord isolation (SI), i.e. complete spinal cord tra...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00665.x
更新日期：2007-01-01 00:00:00
abstract：:Early hominins formed large and thick-enamelled cheek-teeth within relatively short growth periods as compared with modern humans. To understand better the developmental basis of this process, we measured daily enamel increments, or cross striations, in 17 molars of Plio-Pleistocene hominins representing seven differe...
journal_title：Journal of anatomy
pub_type： 历史文章,杂志文章
doi：10.1111/j.1469-7580.2008.00938.x
更新日期：2008-08-01 00:00:00
abstract：:Current nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy and physiology of these nerves to highlight their potential as a donor graft. The aim of this study...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12341
更新日期：2015-09-01 00:00:00
abstract：:The effects of bacterial lipopolysaccharide (LPS) on the expression of surface antigens including major histocompatibility complex (MHC) and complement type 3 (CR3) receptors on microglial cells in the corpus callosum in postnatal rat brain were investigated. When LPS was injected intravenously (i.v.) in 1-d-old rats,...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Germline stem cells, which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. The germ cells have a special place in the life cycle because they must be able to retain the ability to recreate the organism, a proper...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2008.00930.x
更新日期：2008-07-01 00:00:00
abstract：:Although seen frequently during dissections and autopsies, Hyperostosis frontalis interna (HFI) - a morphological pattern of the frontal bone thickening - is often ignored and its nature and development are not yet understood sufficiently. Current macroscopic classification defines four grades/stages of HFI based on t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12506
更新日期：2016-11-01 00:00:00
abstract：:The aim of this study was to design, develop and employ a method for the acquisition of a significant data base of thickness measurements. The integration of standard histological techniques (step serial sectioning), modern computer technology and a personally developed software package (specifically designed for thic...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:As a member of the most basal clade of extant ray-finned fishes (actinopterygians) and of one of the most basal clades of osteichthyans (bony fishes + tetrapods), Polypterus can provide insights into the ancestral anatomy of both ray-finned and lobe-finned fishes, including those that gave rise to tetrapods. The pecto...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12573
更新日期：2017-04-01 00:00:00
abstract：:The onset and evolution of the meiotic prophase were assessed by histological and cytological techniques in fetal and neonatal ovaries obtained from day 13 postcoitum to day 11 postpartum in the golden hamster (Mesocricetus auratus). The histological technique based on the Feulgen stain and the cytological technique b...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-06-01 00:00:00
abstract：:A histological study has shown that considerable amounts of lipid accumulate in the oxyntico-peptic cells of the proventriculus of domestic fowls deprived of food. Lipid droplets were first seen in the cells 6 hours after commencing the fast and they reached a maximum in 24 hours; a decrease was detected histologicall...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-12-01 00:00:00
abstract：:This paper describes a qualitative and quantitative investigation into the location of the motoneurons innervating the extra-ocular muscles of the rat. Injections of horseradish peroxidase, bisbenzimide, propidium iodide and DAPI-primuline were made either in one or simultaneously in two muscles. Unlike those of the c...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:Arguably, the gold standard of biological repair of articular cartilage lesions is autologous chondrocyte transplantation. Although the clinical outcomes appear to range between good and excellent in most cases, there are, nevertheless, both clinical and biological challenges that remain to improve rehabilitation and ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2006.00624.x
更新日期：2006-10-01 00:00:00
abstract：:Histochemical fibre types classified in sections stained for succinic dehydrogenase (sdh) and myosin ATPase at pH 9.4, were found to be distributed in a consistent manner within the extensor digitorum longus (EDL) and 4 soleus muscles of the adult rat. Simple morphometric techniques applied to complete transverse sect...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:The scapholunate interosseous ligament (SLIL) connects the scaphoid and lunate bones and plays a crucial role in carpal kinematics. Its rupture leads to carpal instability and impairment of radiocarpal joint function. As the ligament is one of the first structures affected in rheumatoid arthritis, we conducted an immu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00552.x
更新日期：2006-06-01 00:00:00
abstract：:Knowledge of the pattern of human craniofacial development in the fetal period is important for understanding the mechanisms underlying the emergence of variations in human craniofacial morphology. However, the precise character of the prenatal ontogenetic development of the human cranium has yet to be fully establish...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00884.x
更新日期：2008-05-01 00:00:00
abstract：:The morphological transition from the simple epidermis that contacts the amniotic fluid of embryonic crocodilians to the adult epidermis required in a terrestrial environment has never been described. We used light and electron microscopy to study the development, differentiation and keratinisation of the epidermis of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19830265.x
更新日期：2001-03-01 00:00:00
abstract：:The study of the underlying mechanisms by which cells respond to mechanical stimuli, i.e. the link between the mechanical stimulus and gene expression, represents a new and important area in the morphological sciences. Several cell types ('mechanocytes'), e.g. osteoblasts and fibroblasts as well as smooth, cardiac and...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1999.19430323.x
更新日期：1999-04-01 00:00:00
abstract：:The aims of the present study were to determine whether nerves that contain nitric oxide synthase (NOS), calcitonin gene-related peptide (CGRP) or substance P (SP) are present in the human vagina and, if so, to determine the pattern of innervation relative to that of other neurotransmitters, particularly vasoactive in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:Several quantitative and morphometric parameters were analysed in the pars principalis of the supraoptic nucleus (SON) of the hypothalamus in control and hypophysectomised rats at several postnatal ages. The cell number in the control group remained approximately constant from Day 1, when it was 5034 +/- 348 (mean +/-...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:The blood supply to the cranial venae cavae on both sides and to the heart was studied macroscopically in 40 adult laboratory shrews (Suncus murinus) of both sexes injected either with Neoprene latex into the abdominal aorta (25 animals) or with Mercox into the left ventricle (15 animals). The 1st branch of the left s...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:The effects of excess iodine on the development of the thyroid gland of chick embryos was assessed following injections of potassium iodide prior to incubation. Iodide injection resulted in a significantly greater thyroid gland weight (goitre) on Day 18 of incubation and a delay in hatching. Histological studies of th...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:Clinical research on the deposition of inhaled substances (e.g. inhaled medications, airborne contaminants, fumes) in the lungs necessitates anatomical models of the airways. Current conducting airway models lack three-dimensional (3D) reality as little information is available in the literature on the distribution of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.0021-8782.2001.00018.x
更新日期：2002-02-01 00:00:00
abstract：:The morphology of the cartilage-marrow interface in chick embryo tibiae has been studied from Day 11 to Day 14. The cartilage-marrow interface did not present a uniform aspect and three different areas could be defined. Most of the interface was lined by fibroblast-like cells, macrophage-like cells and multinucleate g...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:Networks linking single genes to multiple phenotypic outcomes can be founded on local anatomical interactions as well as on systemic factors like biochemical products. Here we explore the effects of such interactions by investigating the competing spatial demands of brain and masticatory muscle growth within the hyper...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13393
更新日期：2021-01-13 00:00:00
