Abstract：
:The effects of excess iodine on the development of the thyroid gland of chick embryos was assessed following injections of potassium iodide prior to incubation. Iodide injection resulted in a significantly greater thyroid gland weight (goitre) on Day 18 of incubation and a delay in hatching. Histological studies of the thyroid gland on Day 12 of incubation revealed that iodide injection had inhibited thyroid follicle development. On Day 14, however, the thyroid glands of the iodide-treated embryos were indistinguishable from controls and on Day 18 the thyroid follicles of the iodide-injected embryos were clearly hypertrophied. In agreement with these light microscopical observations, electron microscopical examination showed conspicuous development of rough endoplasmic reticulum in the follicle cells of both iodide-treated 14 and 18 days old embryos and in those of the corresponding controls. Immunocytochemical studies of the pituitary of 18 days old embryos revealed a depletion of immunoreactive TSH suggesting that the iodide-induced hypertrophy of the thyroid was mediated by an activation of the thyrotropes. Iodide treatment was without effect on plasma levels of T3 and T4 for Day 18 embryos suggesting that the compensatory hypertrophy of the thyroid gland was sufficient to maintain circulating levels of thyroid hormones. The present results demonstrate that, in the embryonic chick thyroid, excess iodine produces effects which occur in two phases. The first phase consists of a transitory inhibition of the formation of follicles; it is followed by a second phase of compensatory hypertrophy resulting in goitre. The first phase probably results from a direct inhibitory effect of iodine on the developing thyroid whereas the second phase probably reflects a stimulation of the thyroid by TSH.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Guo Z,Narbaitz R,Fryer JNsubject
Has Abstractpub_date
1991-06-01 00:00:00pages
157-67eissn
0021-8782issn
1469-7580journal_volume
176pub_type
杂志文章abstract：:Angiogenesis is essential for the replacement of cartilage by bone during growth and repair. In order to obtain a better understanding of the mechanisms regulating vascular invasion at sites of endochondral ossification we have investigated the expression of the endothelial cell-specific mitogen, vascular endothelial ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19440519.x
更新日期：1999-05-01 00:00:00
abstract：:The descending projections to coccygeal spinal segments influencing tail movement were studied by retrograde wheat germ agglutinin-horseradish peroxidase (WGA-HRP) tracing methods in 12 cats. WGA-HRP solution was injected into the 3rd and 4th coccygeal segments and hemisection of the right side of the spinal cord was ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：:Differences are reported in the total calcified tissue/bone marrow ratios and in the total thickness of cortical calcified tissue (lamellar bone and calcified fibrocartilage) between the attachment sites of the quadriceps tendon and the patellar ligament in man. The greatest amount of calcified tissue is at the insert...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12677
更新日期：2017-12-01 00:00:00
abstract：:Many studies have demonstrated the association between facet tropism and disc herniation in the lumbar spine. Some of them found that lumbar disc herniation was on the side of the more sagittal facet joint interface. However, little is understood about the association of facet tropism with disc herniation in the cervi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13151
更新日期：2020-05-01 00:00:00
abstract：:Lacking fur, living in eusocial colonies and having the longest lifespan of any rodent, makes naked mole-rats (NMRs) rather peculiar mammals. Although they exhibit a high degree of polymorphism, skeletal plasticity and are considered a novel model to assess the effects of delayed puberty on the skeletal system, scarce...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13381
更新日期：2020-12-11 00:00:00
abstract：:Nearly two thirds of the approximately 700 species of living salamanders are lungless. These species respire entirely through the skin and buccopharyngeal mucosa. Lung loss dramatically impacts the configuration of the circulatory system but the effects of evolutionary lung loss on cardiac morphology have long been co...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12535
更新日期：2017-01-01 00:00:00
abstract：:Amniotic fluid-derived stem cells (AFSCs) are a unique stem cell source that may have great potential for use in tissue engineering (TE) due to their pluripotentiality. AFSCs have previously shown angiogenic potential and may present an alternative cell source for endothelial-like cells that could be used in range of ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12283
更新日期：2015-12-01 00:00:00
abstract：:The density and distribution of nerve fibres immunoreactive to antisera for PGP 9.5 (general neuronal marker), calcitonin gene related peptide (CGRP) and substance P (SP) (markers for sensory neurons), as well as neuropeptide Y (NPY), vasoactive intestinal peptide (VIP) and tyrosine hydroxylase (TH) (markers for auton...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1997.19120245.x
更新日期：1997-08-01 00:00:00
abstract：:The testicular capsule was studied histologically, morphometrically, ultrastructurally and immunohistochemically in the Japanese quail, domestic fowl, turkey and duck (all members of the Galloanserae). The testicular capsule was, relative to mammals, thin, being 81.5 +/- 13.7 microm in the quail, 91.7 +/- 6.2 microm i...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00726.x
更新日期：2007-06-01 00:00:00
abstract：:The objective of the current study was to determine the tissue distribution of cells derived from the area opaca in heterospecific quail-chick blastodermal chimeras. Quail-chick chimeras were constructed by transferring dissociated cells from the area opaca of the stage X-XII (EG&K) quail embryo into the subgerminal c...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01168.x
更新日期：2010-01-01 00:00:00
abstract：:The cellular changes in the ileum and duodenum and in the mesenteric and prefemoral lymph nodes of gnotobiotic piglets were observed following feeding with a live culture of a non-pathogenic E. coli. There was a rapid and intense reaction in the lower ileum, and follicles were formed; germinal centres were formed in t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:The development of Schmidt-Lanterman incisures was investigated in the rat sural nerve during an active phase of postnatal myelination (5-21 days post partum). Two distinct populations of incisures were recognised and the following nomenclature for their developmental stages is proposed. Primary incisures which appear...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:Developing Xenopus embryos treated during gastrulation with 22 micrograms/l of salmar calcitonin in the ambient water develop into larvae exhibiting a decrease in interocular distance. In view of the hypocalcaemic properties of calcitonin and the importance of calcium ions in cell aggregation, this phenomenon has been...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Mastoid canals (tunnels) were observed in 41 (7.7%) of 265 dry human skulls. The canals were 2-27 mm long. This feature has not been reported before. dissection of 30 mastoid regions in cadavers showed that the canals contained a branch of the occipital artery and a vein. It is possible that during development of the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:It is well accepted that the aortic plexus is a network of pre- and post-ganglionic nerves overlying the abdominal aorta, which is primarily involved with the sympathetic innervation to the mesenteric, pelvic and urogenital organs. Because a comprehensive anatomical description of the aortic plexus and its connections...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12251
更新日期：2015-01-01 00:00:00
abstract：:The moment arm of a muscle represents its leverage or torque-producing capacity, and is indicative of the role of the muscle in joint actuation. The objective of this study was to undertake a systematic review of the moment arms of the major muscles spanning the glenohumeral joint during abduction, flexion and axial r...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12903
更新日期：2019-01-01 00:00:00
abstract：:The unusual occurrence of skeletal muscle in the pineal gland of the bat Rhinopoma microphyllum is described. Individual muscle fibres were centrally placed and were incompletely encapsulated by a labyrinthine network of widened spaces filled with electron-dense material. The 2.4 micron long sarcomeres consisted of we...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:Male rats undernourished from about birth until 100 days of age were nutritionally rehabilitated until 200 days. Six control and six experimental rats were anaesthetised and X-rayed at each of 50, 100 and 200 days. Measurements of various skeletal dimensions, and estimates of skeletal maturity, were made from these ra...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
abstract：:Two endocrine cell types were found in the metaplastic epithelium of gall bladders removed for gall stones. The endocrine cell type I resembled the EC (enterochromaffin) cell of the normal stomach mucosa. The homogeneous and electron-dense secretory granules were variable in size and shape and mainly located in the su...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-11-01 00:00:00
abstract：:This study was carried out on 208 Nigerian bony palates in dried skulls and on 30 palates obtained from Nigerian cadavers. Out of 208 dried skulls examined, there was a unilateral spine in 21.1% of cases, a bilateral spine in 36.5% and a bony canal in 5.7%. Of the dissected palates 30% revealed the presence of an osse...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：:The effect of serum prolactin elevation on the growth and development of the rat breast was investigated. Oral administration of the dopamine antagonist, perphenazine, led to a 5-10-fold elevation of serum prolactin after two days of treatment which was maintained for the 54 days of study. A significant (P less than 0...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:The spatiotemporal distribution of macrophages in the uterine wall of mice in the second half of pregnancy and the early postpartum period has been studied. Macrophages were identified using a combination of morphological criteria, the capacity to endocytose horseradish peroxidase and the expression of the Mac-1 antig...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:The dogma that cutaneous wound healing is impaired as a function of age is largely unsubstantiated. This can be attributed to poor experimental design of human studies, the lack of subject characterisation with the exclusion of disease processes, and the study of inappropriate animal models. Structural and functional ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:The geometry-dependent functioning of the meniscus indicates that detailed knowledge on 3D meniscus geometry and its inter-subject variation is essential to design well functioning anatomically shaped meniscus replacements. Therefore, the aim of this study was to quantify 3D meniscus geometry and to determine whether ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12223
更新日期：2014-10-01 00:00:00
abstract：:Although it is generally assumed that herbivores have more voluminous body cavities due to larger digestive tracts required for the digestion of plant fiber, this concept has not been addressed quantitatively. We estimated the volume of the torso in 126 terrestrial tetrapods (synapsids including basal synapsids and ma...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12557
更新日期：2017-02-01 00:00:00
abstract：:Lymphatics in the diaphragm form a specialised system draining fluid from the peritoneal cavity and returning it to the vascular system. Fluid enters subperitoneal lymphatic lacunae, between muscle fibres of the diaphragm, the lacunae being separated from the peritoneal cavity by a barrier comprising, successively, ly...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
abstract：:Fresh specimens of human peritoneum collected from heart-beating cadaver organ donors have been examined by transmission electron microscopy. Samples were taken from the anterior abdominal wall and from the surfaces of the liver, stomach and diaphragm. The mesothelium consisted of a single layer of flattened cells gen...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：:The bronchial tree was investigated in 37 pairs of lungs of adult dogs using dissection and corrosion techniques. The external morphology of the lungs and their lobes has been described. The right lung was divided by deep fissures into four lobes, the apical, the middle, the diaphragmatic and the intermediate. The lef...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：:Current nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy and physiology of these nerves to highlight their potential as a donor graft. The aim of this study...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12341
更新日期：2015-09-01 00:00:00
