Abstract：
:The effect of serum prolactin elevation on the growth and development of the rat breast was investigated. Oral administration of the dopamine antagonist, perphenazine, led to a 5-10-fold elevation of serum prolactin after two days of treatment which was maintained for the 54 days of study. A significant (P less than 0.01) 3.4-fold increase in total breast volume was seen by Day 4 of serum prolactin elevation. Breast volume continued to rise up to Day 14 reaching an 8.9-fold peak (P less than 0.001) which was maintained for the duration of the experiment. Epithelial, myoepithelial, lumen and stromal volume changes in the ductular and alveolar compartments were quantified separately. Highly significant (P less than 0.01) volume increases were seen in all components within the first few days of prolactin elevation. Similar time courses of the growth response to elevated serum prolactin were seen in the ductal tissues reaching an approximate 3-fold peak by 7 days in duct epithelium, myoepithelium and duct stroma. Time coordinated growth responses were also seen in the alveolar tissues with larger (7-15-fold) increases in alveolar epithelium, alveolar myoepithelium and alveolar stroma, reaching a peak by 14 days.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Stringer BM,Rowson J,Williams EDsubject
Has Abstractpub_date
1989-02-01 00:00:00pages
249-61eissn
0021-8782issn
1469-7580journal_volume
162pub_type
杂志文章abstract：:Interneurons are an integral part of cortical neuronal circuits. During the past decade, numerous studies have shown that these cells, unlike their pyramidal counterparts that are derived from the neuroepithelium along the lumen of the lateral ventricles, are generated in the ganglionic eminences in the subpallium. Th...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2007.00750.x
更新日期：2007-08-01 00:00:00
abstract：:Literature on the development of the human vagina is abundant; however, contributions concerning the prenatal development of the entire utero-vaginal anlagen (UVA) are rare or carried out in rodents. The primary epithelial characteristics in the adult vagina and uterus are determined during prenatal development and de...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12029
更新日期：2013-04-01 00:00:00
abstract：:It is a challenge to understand how barn owls (Tyto alba) reduce noise during flight to be able to hunt small mammals by audition. Several specializations of the wing and the wing feathers have been implicated in noise reduction. What has been overlooked so far are the fringes at the inner vanes of remiges. We demonst...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2012.01504.x
更新日期：2012-07-01 00:00:00
abstract：:A study has been made, using light and electron microscopy, of GMG cells in the labyrinthine placenta of the mouse. GMG cells were found lying within the lumina of the maternal blood spaces showed degenerative changes and GMG cells were usually found close to these degenerate trophoblast cells. Sometimes the GMG cells...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-12-01 00:00:00
abstract：:Knowledge of variations in the morphology of normal myelinated peripheral nerve fibres is fundamental to subsequent interpretation of neuropathology. It would be advantageous for structural analysis of normal variations to be based on entire myelin internodes, but acquisition of such data via the classic approach of n...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:Four forelimbs of 3 platypuses and 3 forelimbs of 2 echidnas were examined to study the precise form of the brachial plexus and to clarify the structural characteristics of the brachial plexus in phylogeny. The spinal components contributing to the plexus (C4-T2) and the formation patterns of the 3 trunks of the plexu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1997.19030447.x
更新日期：1997-04-01 00:00:00
abstract：:The lungs of 3 small passerine species, having similar body mass but different diurnal activity patterns, were analysed morphometrically to assess the relationship between diurnal activity and pulmonary volumetry at the light and electron microscope levels. The percentage volumes of the major lung and exchange tissue ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1998.19340573.x
更新日期：1998-11-01 00:00:00
abstract：:The cortical representations of the vibrissae of the rat form a matrix in which each whisker has its own area of cortex, called a 'barrel'. The afferent pathways from the periphery travel first to the trigeminal nuclei and thence via the ventroposteromedial thalamus (VPM) to the cortical barrels have been described in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2000.19630379.x
更新日期：2000-04-01 00:00:00
abstract：:Many vertebrates have an ocular skeleton composed of cartilage and/or bone situated within the sclera of the eye. In this study we investigated whether modern and fossil sharks have an ocular skeleton, and whether it is conserved in morphology. We describe the scleral skeletal elements of three species of modern shark...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01077.x
更新日期：2009-06-01 00:00:00
abstract：:The morphology of the epididymal duct and, in particular, the epididymal microvasculature was examined at the light microscope level in young sexually-mature rats (3-5 months) and aged rats (18 months) to investigate the structural changes that may occur within the organ as a result of ageing, and which may predispose...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:The number and topographic distribution of the profiles of degenerating primary afferent fibres were determined within the rat dorsal column 3-4 weeks after division of the lumbar and S2 dorsal roots. The degenerating fibres were identified in toluidine blue-stained 1 micron transverse sections taken at different spin...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-08-01 00:00:00
abstract：:Two endocrine cell types were found in the metaplastic epithelium of gall bladders removed for gall stones. The endocrine cell type I resembled the EC (enterochromaffin) cell of the normal stomach mucosa. The homogeneous and electron-dense secretory granules were variable in size and shape and mainly located in the su...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-11-01 00:00:00
abstract：:The gross and microscopic anatomy of the Cape fur seal heart, lung, liver, spleen, stomach, intestine and kidneys (n = 31 seals) is described. Absolute and relative size of organs from 30 male seals are presented, with histological examination conducted on 7 animals. The relationship between log body weight, log organ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19520235.x
更新日期：1999-08-01 00:00:00
abstract：:The cytoarchitecture of the intra-ocular optic nerve was investigated by light and electron microscopy. Glial cells in the intra-ocular portion are disposed among the axons, either scattered or forming columns, and bordering the nervous parenchyma. Astroglia forms the limiting glia that separates the optic nerve from ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:The number of neurons and glia in the mouse abducens nerve nucleus was estimated at 6, 25, 28 and 31 months of age. There was no significant variation in either the number of neurons (mean 118) or glia (mean 168) or in the glia to neuron ratio (mean 1.42) with age. Mean neuronal and glial nuclear diameters also remain...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:Premature closure of the sagittal suture occurs as an isolated (nonsyndromic) birth defect or as a syndromic anomaly in combination with other congenital dysmorphologies. The genetic causes of sagittal nonsyndromic craniosynostosis (NSC) remain unknown. Although variation of the dysmorphic (scaphocephaly) skull shape ...
journal_title：Journal of anatomy
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1469-7580.2010.01258.x
更新日期：2010-08-01 00:00:00
abstract：:In a study of 80 cavernous sinuses in 40 cadavers, the trochlear nerve entered the cavernous sinus in 87.5% of cases before the crossing, in 7.5% at the crossing and in 5.0% after the crossing of the free and the attached margins of the tentorium cerebelli. In 77.5% of specimens the trochlear nerve showed a marked ben...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:Fixed and unfixed human tendons originating from cadavers and postoperation specimens were examined using inclined parallel beams of light in a reflecting mode. Along the tendon, numerous planes, constantly inclined to the axis, were observed edge-on at the surface and within the interior. Their angle of inclination, ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:On the basis of its internal structure, the ball of the foot can be divided into three transverse areas, each with a different mechanical function: (1) an area proximal to the heads of the metatarsals in which the retinacula cutis are developed into a series of transverse bands, and in which the deep fibres of the pla...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:Internal cranial anatomy is a challenging area to study in fossilized skulls because of small sample sizes and varied post-mortem preservational alterations. This difficulty has led to the lack of correspondence between results obtained from direct osteological observation and from more indirect reconstruction methods...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01427.x
更新日期：2011-12-01 00:00:00
abstract：:The extent of neuronal labelling with horseradish peroxidase (HRP) was examined in rat trigeminal motor neurons at various stages of acrylamide intoxication, following HRP uptake by motor nerve endings in the anterior digastric muscle. After 7 days of acrylamide (5 daily injections of 30 mg acrylamide/kg body weight),...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：:The entire head and neck of a wild adult male Mongolian gazelle (Procapra gutturosa) was dissected with special reference to its enlarged larynx. Two additional adult male specimens taken from the wild were analysed by computer tomography. The sternomandibularis, omohyoideus, thyrohyoideus and hyoepiglotticus muscles ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00232.x
更新日期：2003-11-01 00:00:00
abstract：:Advances in X-ray computed tomography (CT) have led to a rise in the use of non-destructive imaging methods in comparative anatomy. Among these is contrast-enhanced CT scanning, which employs chemical stains to visualize soft tissues. Specimens may then be 'digitally dissected', producing detailed, three-dimensional d...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13007
更新日期：2019-08-01 00:00:00
abstract：:The epithalamus is a major subdivision of the diencephalon constituted by the habenular nuclei and pineal complex. Structural asymmetries in this region are widespread amongst vertebrates and involve differences in size. neuronal organisation, neurochemistry and connectivity. In species that possess a photoreceptive p...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.2001.19910063.x
更新日期：2001-07-01 00:00:00
abstract：:The number and diameter of fibres in three different muscles from streptozotocin-diabetic rats were compared to the same muscles from animals of two, non-diabetic, control groups. The animals of the weight control group were fed a restricted food intake so that they grew at the same rate as the diabetic animals, where...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：:A total histological grade does not necessarily distinguish between different manifestations of cartilage damage or degeneration. An accurate and reliable histological assessment method is required to separate normal and pathological tissue within a joint during treatment of degenerative joint conditions and to sub-cl...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2012.01513.x
更新日期：2012-07-01 00:00:00
abstract：:Developing Xenopus embryos treated during gastrulation with 22 micrograms/l of salmar calcitonin in the ambient water develop into larvae exhibiting a decrease in interocular distance. In view of the hypocalcaemic properties of calcitonin and the importance of calcium ions in cell aggregation, this phenomenon has been...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:A study of the attachments of the musculotendinous fibres of the lumbar erector spinae muscle shows that it is made of two parts: a superficial or costal part, and a deep or vertebral part. The superficial part arises by small fleshy slips from the posterior (superficial) surface as well as the rostral and lateral mar...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：:This study analyses the evaluation of tomographic indicators of tibia structure, assuming that the usual loading pattern shifts from uniaxial compression close to the heel to a combined compression, torsion and bending scheme towards the knee. To this end, pQCT scans were obtained at 5% intervals of the tibia length (...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01201.x
更新日期：2010-04-01 00:00:00
abstract：:Angiogenesis is essential for the replacement of cartilage by bone during growth and repair. In order to obtain a better understanding of the mechanisms regulating vascular invasion at sites of endochondral ossification we have investigated the expression of the endothelial cell-specific mitogen, vascular endothelial ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19440519.x
更新日期：1999-05-01 00:00:00
