Abstract:
:The extent of neuronal labelling with horseradish peroxidase (HRP) was examined in rat trigeminal motor neurons at various stages of acrylamide intoxication, following HRP uptake by motor nerve endings in the anterior digastric muscle. After 7 days of acrylamide (5 daily injections of 30 mg acrylamide/kg body weight), the pattern of HRP labelling was altered from normal, and this changed pattern persisted without further alteration when survival time and dosage were increased to 14 and 21 days (equivalent to 10 X 30 mg/kg and 15 X 30 mg/kg respectively). Six hours after HRP injection, the number of labelled cells in the ipsilateral trigeminal motor nucleus was reduced in treated animals compared to controls. By 18 hours, cells containing label were present in similar numbers to controls; but by 24 hours, the number in treated animals had fallen again, unlike controls in which labelling remained constant between 6 and 24 hours. At longer intervals, this reduction in labelling continued, but more slowly, so that by 96 hours after HRP injection, numbers of labelled cells were again similar in poisoned and control animals. One and three days after a single intramuscular injection of 0.05 microgram botulinum toxin type A, HRP labelling in the trigeminal motor neurons was unaffected, although at three days after toxin, mild chromatolytic changes could be seen in a few of the neurons.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Kemplay S,Cavanagh JBsubject
Has Abstractpub_date
1983-10-01 00:00:00pages
477-82eissn
0021-8782issn
1469-7580journal_volume
137 (Pt 3)pub_type
杂志文章abstract::The seminal vesicles are the glands of male reproductive organs that produce the fluid and nutrient constituents of semen. It has been believed for a long time that the lumen of a seminal vesicle was a single-coiled tubular structure with irregular diverticula. There are several previous reports on the symmetry, diffe...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13269
更新日期:2020-12-01 00:00:00
abstract::Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophage...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::In zoology it is well known that birds are characterized by the presence of feathers, and mammals by hairs. Another common point of view is that avian scales are directly related to reptilian scales. As a skin embryologist, I have been fascinated by the problem of regionalization of skin appendages in amniotes through...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2008.01041.x
更新日期:2009-04-01 00:00:00
abstract::The anterolateral ligament, a distinct structure connecting the lateral femoral epicondyle to the anterolateral proximal tibia, is gaining attention because of its possible function in ensuring internal rotational stability of the tibia. To study the prevalence and precise anatomical characteristics of the anterolater...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12826
更新日期:2018-08-01 00:00:00
abstract::The dogma that cutaneous wound healing is impaired as a function of age is largely unsubstantiated. This can be attributed to poor experimental design of human studies, the lack of subject characterisation with the exclusion of disease processes, and the study of inappropriate animal models. Structural and functional ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::This study reports the tissue distribution of Hepatocyte Growth Factor-Scatter Factor (HGF/SF) in human fetal tissue using Northern analysis and in situ hybridisation techniques. In tissue from fetuses of 9-17 wk gestational age, the 6 kb mRNA transcript for HGF/SF was demonstrated in many tissues but prominently in l...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Elastic fibres, which are intimately associated with collagen, a major component of the urethra, have been assumed to contribute to the resting urethral closure pressure. The Miller stain for elastin was used to demonstrate elastic fibres in cryostat sections of guinea pig bladder base, vesicourethral junction (VUJ) a...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19530447.x
更新日期:1999-10-01 00:00:00
abstract::The histological structure of the oesophagus of the camel in different parts of its course was investigated with tissues from seven camels, and with haematoxylin and eosin and Masson's trichrome stain. Gross dissections confirmed the orientation of the muscle fibres in the tunica muscularis. The epithelium showed heav...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::The entire lengths of central and peripheral myelin sheaths on the same ventral motoneuron axons of young rats were studied during the rapid early phase of myelination which occurs during the first 2 weeks after birth. Sheath thickness varied along central internodes at all ages, though this variation was less in the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-08-01 00:00:00
abstract::Kinetic changes have been studied in the transitional cells of the marrow in normal, hypoxic (0.5 atm) and rebound rats. Suspensions of marrow cells were incubated with tritiated thymidine for 1 hour, and the percentage of labelled transitionals of all sizes, as well as of large transitionals, was couinted in radioaut...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::Continuous tooth replacement is common for tetrapods, but some groups of acrodont lepidosaurs have lost the ability to replace their dentition (monophyodonty). Acrodonty, where the tooth attaches to the apex of the jawbone, is an unusual form of tooth attachment that has been associated with the highly autapomorphic c...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12754
更新日期:2018-03-01 00:00:00
abstract::The axolotl Ambystoma mexicanum is one of the most used model organisms in evolutionary, developmental and regenerative studies, particularly because it can reconstitute a fully functional and complete forelimb/hindlimb. Surprisingly, there is no publication that describes all the pectoral and forelimb muscles of this...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01567.x
更新日期:2012-12-01 00:00:00
abstract::The frequency with which the gonadal arteries follow a recurrent course, upwards and arching over the renal veins before descending to the gonads, is recorded for the South African Negro. The gonadal arteries follow such a course on the left side in 17, 2% and on the right side in 22% of cases. This incidence for arch...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract::In stem-cell research a major difficulty is caused by the lack of distinctive features that allow the identification of human mesenchymal stem cells (hMSC). Until now, there has been no specific marker and the most common way to identify hMSC is by their characteristic stem-cell properties: self-replication and differ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2004.00252.x
更新日期:2004-02-01 00:00:00
abstract::Neural stem cells are a multipotent population of tissue-specific stem cells with a broad but limited differentiation potential. However, recent studies have shown that over-expression of the pluripotency gene, Oct4, alone is sufficient to initiate a process by which these can form 'induced pluripotent stem cells' (iP...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2010.01269.x
更新日期:2010-09-01 00:00:00
abstract::Muscle moment arms were measured for major muscles of the pelvic limb of the ostrich (Struthio camelus) in order to assess specific functional behaviour and to apply this to locomotor performance. Pelvic limbs of six juvenile ostriches were used for this study. The tendon travel technique was used to measure moment ar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00762.x
更新日期:2007-09-01 00:00:00
abstract::The absolute number of parvicellular and magnocellular neurons in the red nucleus was estimated using design-based stereological counting methods and systematic random sampling techniques. Six young adult male rats, and a complete set of serial 40-μm glycolmethacrylate sections for each rat, were used to quantify neur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12495
更新日期:2016-09-01 00:00:00
abstract::This study demonstrates that the earlier growth spurt in vertebral height in females and the greater growth in vertebral transverse diameter in males, both give rise to sexual dimorphism in vertebral shape, female vertebral bodies being significantly more slender than male vertebral bodies from the age of 8 years onwa...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract::The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19410089.x
更新日期:1999-01-01 00:00:00
abstract::Fertilised chicken eggs were incubated for 48 hours while exposed to pulsed trains of magnetic fields having a duration of 0-5 ms, a rise time of 42 microsecond, and a pulse repetition rate of 100 at a magnetic field flux density of 1 microT. Some eggs were exposed to 1,552 rad X-rays as a positive control. After expo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::Apoptosis is an essential physiological process in embryonic development. In the developing eye of vertebrates, three periods of developmental apoptosis can be distinguished: early, intermediate and later. Within the apoptosis pathway, caspases play a crucial role. It has also been shown that HSP110 may have a potenti...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00719.x
更新日期:2007-05-01 00:00:00
abstract::The vomeronasal system (VNS) has been extensively studied within specific animal families, such as Rodentia. However, the study of the VNS in other families, such as Canidae, has long been neglected. Among canids, the vomeronasal organ (VNO) has only been studied in detail in the dog, and no studies have examined the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13254
更新日期:2020-11-01 00:00:00
abstract::Assessment of global endocranial morphology and regional neuroanatomical changes in early hominins is critical for the reconstruction of evolutionary trajectories of cerebral regions in the human lineage. Early evidence of cortical reorganization in specific local areas (e.g. visual cortex, inferior frontal gyrus) is ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12745
更新日期:2018-02-01 00:00:00
abstract::The objective of the current study was to determine the tissue distribution of cells derived from the area opaca in heterospecific quail-chick blastodermal chimeras. Quail-chick chimeras were constructed by transferring dissociated cells from the area opaca of the stage X-XII (EG&K) quail embryo into the subgerminal c...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2009.01168.x
更新日期:2010-01-01 00:00:00
abstract::Fluorescence microscopy and transmission electron microscopy were used to study peribronchial ganglia of cats. An osmiophilic substance that is selectively taken up into the synaptic vesicles of adrenergic nerves (5-hydroxydopamine) was used to help differentiate adrenergic and non-adrenergic terminals. Peribronchial ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::In order to clarify the fundamental structure of the host defence mechanism in chicken caeca, a detailed analysis of the distribution of lymphoid nodules (LNs) was carried out on longitudinal sections of both the mesenteric (side of the ileocaecal ligament) and the antimesenteric mucosa. An overwhelming majority of so...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1998.19220293.x
更新日期:1998-02-01 00:00:00
abstract::The present study analyses the organization and selected neurochemical features of the claustrum and visual cortex of the sheep, based on the patterns of calcium-binding proteins expression. Connections of the claustrum with the visual cortex have been studied by tractography. Parvalbumin-immunoreactive (PV-ir) and Ca...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13302
更新日期:2021-01-01 00:00:00
abstract::In an adult skull a pre-interparietal bone was found to be present in two symmetrical pieces on either side of the midline. This is the result of failure of fusion of a third pair of centres with each other on the midline. The possibilities of variations due to non-fusion of various pairs of the centres in the interpa...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract::The distribution and composition of endogenous lipids in articular cartilage and transport of exogenous fatty acids have been investigated on a microscopic scale in fresh bovine articular cartilage. To investigate the distribution and composition of the endogenous lipids, hyperspectral Raman maps were taken of chondro...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12624
更新日期:2017-07-01 00:00:00
abstract::The urethra is the main place of entry for sexually transmitted pathogens. However, there is little literature on the morphology of the urogenital system, principally the urethra and ducts of the sex accessory glands. The Mongolian gerbil is an insectivorous, herbivorous and monogamous rodent with nocturnal habits; it...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00181.x
更新日期:2003-05-01 00:00:00