Abstract：
:The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities to be studied in detail without disturbing the tissue architecture. Only one microaneurysm, defined as any focal capillary dilation, was observed in 10 normal eyes but numerous microaneurysms were seen in 4 out of 5 diabetic retinas; counts varied between 0 and 26 per 0.41 mm2 sample area. Microaneurysms were classified into 3 categories according to morphology: saccular, fusiform and focal bulges. Most were saccular, these having no preferred orientation. The majority of microaneurysms were associated with just 2 vessels suggesting they were unlikely to develop at vascular junctions. The majority were observed to originate from the inner nuclear layer and were therefore in the deeper part of the inner retinal capillary plexus. Variation in the staining of microaneurysms may correlate with endothelial dysfunction seen clinically as dye leakage during fluorescein angiography.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Moore J,Bagley S,Ireland G,McLeod D,Boulton MEdoi
10.1046/j.1469-7580.1999.19410089.xkeywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
89-100eissn
0021-8782issn
1469-7580journal_volume
194 ( Pt 1)pub_type
杂志文章abstract：:This study set out to determine the pattern of development and distribution of the interstitial cells of Cajal (ICC) in the intestinal tract of the equine fetus and neonate. Intestinal tissue samples from 12 naturally aborted equine fetuses and three euthanized neonates were collected and fixed in formalin prior to ap...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.0021-8782.2004.00315.x
更新日期：2004-07-01 00:00:00
abstract：:The pectoralis muscle from growing house sparrows was investigated using linear, gravimetric, histological and ultrastructural techniques. The structure of the muscle at different stages of development was discussed in relation to known behavioural activities, such as the onset of regular wing exercising and thermogen...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-12-01 00:00:00
abstract：:The aim of this study is to quantify and statistically model the age-related decline in the fibrous connective tissue interface of the anterior fontanelle in modern Australian infants, using three-dimensional, semi-automated computed-assisted design protocols. Non-linear regression with variance models, using power fu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13200
更新日期：2020-08-01 00:00:00
abstract：:An electron microscopic study of myelination was carried out in the anterior limb of the anterior commissure of the mouse brain. The total number of axons increased from 48 700 at 17 days post-conception to 286 500 at 11 days postnatum. The first evidence of myelination was the presence of a few promyelin fibres at 8 ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-02-01 00:00:00
abstract：:The distribution of mRNAs and antigens of tissue type (t) and urokinase type (u) plasminogen activators (PA) plus their corresponding inhibitors, type-1 (PAI-1) and type-2 (PAI-2) were studied in human and rhesus monkey placentae by in situ hybridisation and immunocytochemistry. Specific monkey cRNA and antibodies aga...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19420183.x
更新日期：1999-02-01 00:00:00
abstract：:Mastoid canals (tunnels) were observed in 41 (7.7%) of 265 dry human skulls. The canals were 2-27 mm long. This feature has not been reported before. dissection of 30 mastoid regions in cadavers showed that the canals contained a branch of the occipital artery and a vein. It is possible that during development of the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:The collagen in the endoneurium is present as argyrophilic reticular fibres, which show up as thin, weakly birefringent greenish fibres when studied by aid of the Picrosirius-polarization method, and are composed of loosely arranged thin collagen fibrils. The epineurium consists of thick non-argyrophilic collagen fibr...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-08-01 00:00:00
abstract：:Lateral cephalographs from 220 normal adolescent white orthodontic patients, and of individuals with craniofacial dysostosis and oculodento-osseous dysplasia were studied. Variations were observed in the morphology of the posterior margins of the superior articular processes, vertebral artery canals being present in 8...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:In embryology, the infracardiac bursa (ICB) is a well-known derivative separated from the omental bursa. During surgeries around the esophagogastric junction (EGJ), surgeons often encounter a closed space considered to be equivalent to the ICB, but the macroscopic anatomy in adults is hardly known. This study aimed to...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12989
更新日期：2019-07-01 00:00:00
abstract：:The morphology of the cartilage-marrow interface in chick embryo tibiae has been studied from Day 11 to Day 14. The cartilage-marrow interface did not present a uniform aspect and three different areas could be defined. Most of the interface was lined by fibroblast-like cells, macrophage-like cells and multinucleate g...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:Human beings stand upright with the chain of balance beginning at the feet, progressing to the lower limbs (ankles, knees, hip joints, pelvis), each of the spinal segments, and then ending at the cranium to achieve horizontal gaze and balance using minimum muscle activity. The details of the alignment and balance of t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12586
更新日期：2017-05-01 00:00:00
abstract：:Differences are reported in the total calcified tissue/bone marrow ratios and in the total thickness of cortical calcified tissue (lamellar bone and calcified fibrocartilage) between the attachment sites of the quadriceps tendon and the patellar ligament in man. The greatest amount of calcified tissue is at the insert...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:How changes in anatomy affect joint biomechanics can be studied using musculoskeletal modelling, making it a valuable tool to explore joint function in healthy and pathological joints. However, gathering the anatomical, geometrical and physiological data necessary to create a model can be challenging. Very few integra...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12877
更新日期：2018-11-01 00:00:00
abstract：:The importance of controlling litter size in growth studies is verified for Rattus norvegicus. A method of studying growth of the cranial base bones in the median sagittal plane is described and figures for growth rate in micrometres per day have been produced for the age range 4-480 days. The age range 4 to 80 days i...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:This paper reports on the development of a theoretical model to simulate the growth and repair of microdamage in bone. Unlike previous theories, which use simplified descriptions of damage, this approach models each individual microcrack explicitly, and also models the basic multicellular units (BMUs) that repair crac...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00194.x
更新日期：2003-08-01 00:00:00
abstract：:The development of sensory innervation in long bones was investigated in rat tibia in fetuses on gestational days (GD) 16-21 and in neonates and juvenile individuals on postnatal days (PD) 1-28. A double immunostaining method was applied to study the co-localization of the neuronal growth marker growth-associated prot...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2005.00434.x
更新日期：2005-08-01 00:00:00
abstract：:Darwin's finches are a model system in ecological and evolutionary research, but surprisingly little is known about their skull morphology and development. Indeed, only the early beak development and external variation in adult beak shape has been studied. Understanding the development of the skull from embryo up to t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01388.x
更新日期：2011-08-01 00:00:00
abstract：:The objective of the present study was to measure the lines of action of 18 major muscles and muscle sub-regions crossing the glenohumeral joint of the human shoulder, and to compute the potential contribution of these muscles to joint shear and compression during scapular-plane abduction and sagittal-plane flexion. T...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01090.x
更新日期：2009-08-01 00:00:00
abstract：:The spatiotemporal distribution of macrophages in the uterine wall of mice in the second half of pregnancy and the early postpartum period has been studied. Macrophages were identified using a combination of morphological criteria, the capacity to endocytose horseradish peroxidase and the expression of the Mac-1 antig...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:A quantitative analysis of the motor innervation of intrafusal muscle fibres is described, based on teased silver-impregnated spindles of the tenuissimus muscle of the cat. Included in the analysis are the number and distribution of intrafusal branches of both skeletofusimotor (beta) and purely fusimotor (gamma) axons...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:The fine structure of the intercellular junctions of the hen parathyroid gland was studied using freeze-fracture replicas and thin sections. In the conventional thin sections, desmosomes, intermediate junctions (maculae adherentes) and gap junctions were observed, and in the lanthanum-fixed sections, tight junctions (...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:The behavioral differences in muscle use are related to the fiber type composition of the muscles among other variables. The aim of this study was to examine the degree of heterogeneity in the fiber type composition in the rat temporalis muscle. The temporalis muscle was taken from 10-week-old Wistar strain male rats ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00990.x
更新日期：2008-12-01 00:00:00
abstract：:The distribution and composition of endogenous lipids in articular cartilage and transport of exogenous fatty acids have been investigated on a microscopic scale in fresh bovine articular cartilage. To investigate the distribution and composition of the endogenous lipids, hyperspectral Raman maps were taken of chondro...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12624
更新日期：2017-07-01 00:00:00
abstract：:Examination of spinal cords of 5 days old mice showed a number of examples of oligodendrocytes, in various phases of mitosis, which remained in contact with the axons which they were myelinating. Cells in prophases had thick processes between the perikaryon and the myelinating axons but as mitosis proceeded the oligod...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：:Arguably, the gold standard of biological repair of articular cartilage lesions is autologous chondrocyte transplantation. Although the clinical outcomes appear to range between good and excellent in most cases, there are, nevertheless, both clinical and biological challenges that remain to improve rehabilitation and ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2006.00624.x
更新日期：2006-10-01 00:00:00
abstract：:A comparison of the relative position of the dorsoventral axes of the bases and heads of the metacarpal bones shows that these do not lie in the same plane, and that torsion can therefore be said to exist in these bones. Torsion is such that the heads of the second and third metacarpals appear to be rotated laterally ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：:The feet of apes have a different morphology from those of humans. Until now, it has merely been assumed that the morphology seen in humans must be adaptive for habitual bipedal walking, as the habitual use of bipedal walking is generally regarded as one of the most clear-cut differences between humans and apes. This ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12201
更新日期：2014-08-01 00:00:00
abstract：:Proximal femoral morphology and associated musculature are of special relevance to the understanding of hominoid locomotor systems. Knowledge of bone-muscle correspondence in extant hominoids forms an important comparative basis for inferring structure-function relationships in fossil hominids. However, there is still...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12270
更新日期：2015-03-01 00:00:00
abstract：:The presence of nerve fibres in the medulla of the chick thymus has been investigated ultrastructurally. Unmyelinated nerve fibres were found not only in the perivascular space but also among the myoid cells. The nerve fibres were situated in close proximity to the myoid cells. The unmyelinated axons, containing predo...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
