Abstract:
:This study reports the tissue distribution of Hepatocyte Growth Factor-Scatter Factor (HGF/SF) in human fetal tissue using Northern analysis and in situ hybridisation techniques. In tissue from fetuses of 9-17 wk gestational age, the 6 kb mRNA transcript for HGF/SF was demonstrated in many tissues but prominently in liver, intestine, gall bladder and spleen. In situ hybridisation demonstrated that HGF/SF expression was not confined to mesenchymal tissues, as suggested by previous studies but was expressed in epithelial tissues, particularly in small intestine, keratinising epithelium of tongue, skin and oesophagus. In the small intestine epithelial expression was strikingly regional, being confined to the crypt region, the site of enterocyte proliferation. Northern analysis of tissues for c-met mRNA, representing expression of the HGF/SF receptor, demonstrated receptor expression in all tissues studied except the thyroid gland.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Wang Y,Selden C,Farnaud S,Calnan D,Hodgson HJsubject
Has Abstractpub_date
1994-12-01 00:00:00pages
543-51eissn
0021-8782issn
1469-7580journal_volume
185 ( Pt 3)pub_type
杂志文章abstract::The differentiation and patterning of tendon fibroblasts is at present a poorly understood aspect of musculoskeletal development in the vertebrate limb. Precursors of tendon fibroblasts originate in the somatic mesoderm adjacent to the early limb bud and gradually become incorporated into the limb mesenchyme as develo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00145.x
更新日期:2003-01-01 00:00:00
abstract::A morphometric analysis was made of nuclei and cytoplasmic structures in electron micrographs of chondrocytes in the non-calcified layer of articular cartilage of the femoral condyles in adult mouse and dog and of the human incus. Mitochondrial volume density (% cytoplasm) was lower in dog than in mouse cells or cells...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::The anterolateral ligament, a distinct structure connecting the lateral femoral epicondyle to the anterolateral proximal tibia, is gaining attention because of its possible function in ensuring internal rotational stability of the tibia. To study the prevalence and precise anatomical characteristics of the anterolater...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12826
更新日期:2018-08-01 00:00:00
abstract::The three kinds of keratinized epithelium evident on gross examination of the soft palate of Wistar albino rats were studied by scanning and transmission electron microscopy. Scanning indicated a central area where the epithelium showed numerous fine folds and papillae, more lateral areas which were smooth, and most l...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::Motor control circuitry of the central nervous system must be flexible so that motor behaviours can be adapted to suit the varying demands of different states, developmental stages, and environments. Flexibility in motor control is largely provided by neuromodulatory systems which can adjust the output of motor circui...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12063
更新日期:2014-01-01 00:00:00
abstract::This study was done in order to investigate the normal ultrastructure of well-preserved mouse spinal canal ependyma using light, scanning and transmission electron microscopy. The ependymal lining was found to consist of a simple, cuboidal epithelium essentially similar to the unspecialized cuboidal ependyma of the br...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-10-01 00:00:00
abstract::The morphology of the epididymal duct and, in particular, the epididymal microvasculature was examined at the light microscope level in young sexually-mature rats (3-5 months) and aged rats (18 months) to investigate the structural changes that may occur within the organ as a result of ageing, and which may predispose...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::The formation of a placenta is critical for successful mammalian pregnancy and requires remodelling of the uterine epithelium. In eutherian mammals, remodelling involves specific morphological changes that often correlate with the mode of embryonic attachment. Given the differences between marsupial and eutherian plac...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12610
更新日期:2017-07-01 00:00:00
abstract::The present paper describes a novel structure, termed the peri-albumen layer, in the egg-envelopes of the quail Coturnix japonica. It reacts with Alcian blue and exists between the egg white and the shell membrane. Ultrastructurally, it is of fine granular structure and forms a fenestrate sheet, the width of which is ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00197.x
更新日期:2003-07-01 00:00:00
abstract::Interference with venous outflow from a limb to stimulate fracture repair and bone growth has a long history, and its beneficial effects have been confirmed by many experimental and clinical studies. With the development of fracture fixation systems, the therapeutic use of circulatory intervention became redundant. Re...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::Rodents are defined by a uniquely specialized dentition and a highly complex arrangement of jaw-closing muscles. Finite element analysis (FEA) is an ideal technique to investigate the biomechanical implications of these specializations, but it is essential to understand fully the degree of influence of the different i...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2011.01436.x
更新日期:2011-12-01 00:00:00
abstract::Genetic mutation leads to anatomical variation only indirectly because many proteins involved in generating anatomical structures in embryos operate cooperatively within molecular networks. These include gene-regulatory or control networks (CNs) for timing, signaling and patterning together with the process networks (...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12205
更新日期:2014-08-01 00:00:00
abstract::Although laryngeal morphology often reflects adaptations for vocalization, the structural consequences of selection for particular aspects of vocal behavior remain poorly understood. In this study, we investigated the effects of increased ultrasonic calling in pups on the adult larynx morphology in selectively bred ra...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13366
更新日期:2021-01-21 00:00:00
abstract::The backbone or vertebral column is the defining feature of vertebrates and is clearly metameric. Given that vertebrae arise from segmented paraxial mesoderm in the embryo, this metamerism is not surprising. Fate mapping studies in a variety of species have shown that ventromedial sclerotome cells of the differentiate...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1046/j.1469-7580.2001.19910177.x
更新日期:2001-07-01 00:00:00
abstract::The fabella is a sesamoid bone located in the gastrocnemius behind the lateral femoral condyle. In humans, fabellae are 3.5 times more common today than they were 100 years ago, with prevalence rates varying between and within populations. In particular, fabellae have been assumed to be more common in Asians than non-...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13091
更新日期:2020-02-01 00:00:00
abstract::Because the cornea is optimized for refraction, it relies on supporting tissues for moistening and nutrition and in particular for immune protection. Its main support tissue is the conjunctiva, in addition to the lacrimal gland, the latter which provides soluble mediators via the tear film. The cornea and conjunctiva ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2005.00394.x
更新日期:2005-03-01 00:00:00
abstract::This study describes the degenerative changes of the axon terminals making synaptic contacts with the neurons in the submucous ganglia of guinea pig small and large intestines following left or right cervical vagotomy. There were no noticeable ultrastructural changes 1 d after the operation. Beginning at the 3rd posto...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Nearly two thirds of the approximately 700 species of living salamanders are lungless. These species respire entirely through the skin and buccopharyngeal mucosa. Lung loss dramatically impacts the configuration of the circulatory system but the effects of evolutionary lung loss on cardiac morphology have long been co...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12535
更新日期:2017-01-01 00:00:00
abstract::Scanning microinterferometric measurements were made of matrix dry mass in the intermediate layer of normal rabbit patellar articular cartilage and in the area surrounding standard, experimental, full-thickness lesions of 1-5 mm diameter. The lesions were created in 1 kg animals and were allowed to heal for up to 3 we...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract::Non-ionic, low-osmolar contrast agents (CAs) used for computed tomography, such as Optiray (ioversol) and Iomeron (iomeprol), are associated with the reduced risk of adverse reactions and toxicity in comparison with ionic CAs, such as Hexabrix. Hexabrix has previously been used for imaging articular cartilage but has ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13271
更新日期:2020-12-01 00:00:00
abstract::The axolotl Ambystoma mexicanum is one of the most used model organisms in evolutionary, developmental and regenerative studies, particularly because it can reconstitute a fully functional and complete forelimb/hindlimb. Surprisingly, there is no publication that describes all the pectoral and forelimb muscles of this...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01567.x
更新日期:2012-12-01 00:00:00
abstract::Horns are permanent structures projecting from the head of bovids, consisting of a bony horncore covered with a layer of skin and then a sheath of keratinous material showing variability of growth intensity based on nutrition. From the point of view of the horn's mechanical properties, the keratin sheath has been wide...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12708
更新日期:2018-01-01 00:00:00
abstract::A comparison of the relative position of the dorsoventral axes of the bases and heads of the metacarpal bones shows that these do not lie in the same plane, and that torsion can therefore be said to exist in these bones. Torsion is such that the heads of the second and third metacarpals appear to be rotated laterally ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract::The surface coating of the alveolar macrophages and pneumonocytes of hamster lung was studied using an electron microscopy technique. Slices of lung tissue were fixed in aldehyde, labelled with a battery of lectin-horseradish peroxidase conjugates, incubated in a diaminobenzidine-hydrogen peroxide medium and then post...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-06-01 00:00:00
abstract::Trabecular bone microstructural parameters, including trabecular thickness, spacing, and number, have been reported to scale with animal size with negative allometry, whereas bone volume fraction is animal size-invariant in terrestrial mammals. As for the majority of scaling patterns described in animals, its underlyi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12278
更新日期:2015-03-01 00:00:00
abstract::The natural radiographic appearance of the various bones of the skeleton are described for several strains of laboratory mice. The Harwell substrains of CBA, A and 101 are generally similar and become osteoporotic on ageing. Harwell C57BL have similar, but more delicately chiseled, bones. Harwell C3H mice have bones w...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::Kinetic changes have been studied in the transitional cells of the marrow in normal, hypoxic (0.5 atm) and rebound rats. Suspensions of marrow cells were incubated with tritiated thymidine for 1 hour, and the percentage of labelled transitionals of all sizes, as well as of large transitionals, was couinted in radioaut...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The elastic cartilage of the rat epiglottis was studied with a high-resolution SEM technique. The chondrocytes were found to be anchored in their lacunae by fibrils running in from the territorial matrix. This matrix exhibited a dense network of fibrils arranged tangentially around the lacunar cavity. The fibrils of t...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1979-12-01 00:00:00
abstract::The structure of amniotic papillae in sheep was investigated by light transmission and scanning electron microscopy. Papillae were found on the amnion near the umbilical cord in a majority of the sheep examined, from early mid-term onwards. The papillae possessed a basic connective tissue core with a varying degree of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract::Primates have shoulders adapted to a wide range of locomotor functions from terrestrial pronograde quadrupedalism to highly arboreal suspensory behaviours. The shape of the scapula tightly follows these functional differences. Previous analyses of primate postcrania, including the scapula, indicate that quadrupedal mo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00639.x
更新日期:2006-11-01 00:00:00