Abstract:
:Scanning microinterferometric measurements were made of matrix dry mass in the intermediate layer of normal rabbit patellar articular cartilage and in the area surrounding standard, experimental, full-thickness lesions of 1-5 mm diameter. The lesions were created in 1 kg animals and were allowed to heal for up to 3 weeks. Changes in matrix dry mass were recorded in predetermined zones around the lesions immediately after surgery, and at 1 week, and at 3 weeks post-operatively. After 1 week the rapid early fall in matrix solids was partly offset in areas corresponding to a zone of locally proliferating chondrocytes which appeared to maintain the matrix dry mass close to normal levels. The maximal fall occurred at the extreme edge of the lesion where, it is suggested, total glycosaminoglycan loss had taken place. After 3 weeks the matrix dry mass values had risen to the normal range, apart from a narrow zone adjacent to the wound edge. The findings are discussed in the light of previous quantitative work on the composition of articular cartilage and on the nature of the reactions of cartilage to injury.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Matthews JG,Goldstein DJsubject
Has Abstractpub_date
1977-09-01 00:00:00pages
165-77issue
Pt 1eissn
0021-8782issn
1469-7580journal_volume
124pub_type
杂志文章abstract::The form and position of the developing atrioventricular bundle and its branches has been studied in the hearts of domestic fowl embryos operated upon to induce delayed closure of the interventricular foramen. The operation was performed at 3 days of incubation when the outflow tract of the tubular heart was temporari...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::The ontogeny of the nasolacrimal ducts (NLD) and canals (NLC) are investigated in strepsirrhine and haplorhine primates. Developmental series of serially sectioned fetal, perinatal and adult specimens, in combination with juvenile and adult skulls subjected to high-resolution computed tomography, reveal that the verti...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00682.x
更新日期:2007-02-01 00:00:00
abstract::The human body has evolved to maintain homeostasis through the covering of skin and mucous membranes, which separate the internal environment from the harsh and variable external milieu. Few structures naturally penetrate these coverings, and teeth are the only exception in human beings. Attempts to breach these barri...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00595.x
更新日期:2006-07-01 00:00:00
abstract::Mammalian pregnancy involves remodelling of the uterine epithelium to enable placentation. In marsupials, such remodelling has probably played a key role in the transition from ancestral invasive placentation to non-invasive placentation. Identifying uterine alterations that are unique to marsupials with non-invasive ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13162
更新日期:2020-06-01 00:00:00
abstract::The gene for spondylo-metaphyseal chondrodysplasia (smc) in the mouse disrupts the formation of growth plate cartilage. No cartilage columns are found in the head of the tibia and secondary centres of ossification appear very late. The number of cells labelled with tritiated thymidine is sharply reduced at 16, 18 and ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract::Although the small intestine of the sheep is relatively mature at birth, there are still vacuolated enterocytes present for at least 2 days in distal regions. In the distal regions, vacuolated cells possess a range of vesicle morphology which might be indicative of at least 2 separate routes for enterocyte handling of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Male rats undernourished from about birth until 100 days of age were nutritionally rehabilitated until 200 days. Six control and six experimental rats were anaesthetised and X-rayed at each of 50, 100 and 200 days. Measurements of various skeletal dimensions, and estimates of skeletal maturity, were made from these ra...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
abstract::This paper describes a qualitative and quantitative investigation into the location of the motoneurons innervating the extra-ocular muscles of the rat. Injections of horseradish peroxidase, bisbenzimide, propidium iodide and DAPI-primuline were made either in one or simultaneously in two muscles. Unlike those of the c...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-09-01 00:00:00
abstract::The anatomy of porcine bronchial circulation has not been fully described. The purpose of this study was to investigate the extrapulmonary topographic anatomy of bronchial arteries in pig. Ten pigs weighing 15-25 kg were studied. Between one and four bronchial arteries were found in each pig. The bronchoesophageal art...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2005.00455.x
更新日期:2005-10-01 00:00:00
abstract::Arguably, the gold standard of biological repair of articular cartilage lesions is autologous chondrocyte transplantation. Although the clinical outcomes appear to range between good and excellent in most cases, there are, nevertheless, both clinical and biological challenges that remain to improve rehabilitation and ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2006.00624.x
更新日期:2006-10-01 00:00:00
abstract::Interference with venous outflow from a limb to stimulate fracture repair and bone growth has a long history, and its beneficial effects have been confirmed by many experimental and clinical studies. With the development of fracture fixation systems, the therapeutic use of circulatory intervention became redundant. Re...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assesse...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.01015.x
更新日期:2009-01-01 00:00:00
abstract::The aortic plexus is a network of sympathetic nerves positioned along the infrarenal abdominal aorta. Recently, we characterized the aortic plexus and its ganglia (inferior mesenteric, left/right spermatic, and prehypogastric ganglion) in males; however, the literature minimally describes its anatomy in females. In th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12436
更新日期:2016-05-01 00:00:00
abstract::The glycan composition of the N- and O-linked oligosaccharides of the follicle (Sertoli) cells of the urodele amphibian Pleurodeles waltl testis were identified by lectin histochemistry, performed alone or in combination with enzymatic and chemical deglycosylation methods. The follicle cells were shown to contain: (1)...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19860673.x
更新日期:2001-06-01 00:00:00
abstract::It is well known that large pyroninophilic cell proliferation in regional lymphoid tissue preceds and accompanies cell-mediated immunological reactions. In the present study of lymph node responses in the pregnant rat it was found that there were no significant differences between large pyronionphilic cell counts from...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract::The meaning of the term 'abdomen' has become increasingly ambiguous, as it has to satisfy the contemporary requirements of natural language discourse, literature, gross and radiological anatomy and its role in ontologies supporting electronic records and data modelling. It is critical that there is an agreed understan...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13384
更新日期:2021-01-08 00:00:00
abstract::Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital malformation which associates discordant atrioventricular and ventriculo-arterial connections. Although frequently associated with a ventricular septal defect (VSD), its anatomy remains controversial. This could be due in hearts wi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13097
更新日期:2020-02-01 00:00:00
abstract::In most mammalian species the cardiac skeleton is composed of coarse collagen fibres, fibrocartilage, and pieces of hyaline cartilage. Bone, the os cordis, is a regular constituent of the ruminant heart. The cardiac skeleton of the otter (Lutra lutra) has not previously been described. The skeleton in 30 otter hearts ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2000.19630485.x
更新日期:2000-04-01 00:00:00
abstract::Contracture of collagen fibres in the gubernaculum has been suggested as a mechanism responsible for fetal descent of the testis. We measured the collagen content of the gubernaculum, fetal thigh muscle and umbilical cord tissue by assaying its hydroxyproline and protein content in 194 male pig fetuses between 60 and ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Human beings have considerably expanded cognitive abilities compared with all other species and they also have a relatively larger cerebral cortex compared with their body size. But is a bigger brain the only reason for higher cognition or have other features evolved in parallel? Humans have more and different types o...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12198
更新日期:2015-10-01 00:00:00
abstract::Knowledge of the pattern of human craniofacial development in the fetal period is important for understanding the mechanisms underlying the emergence of variations in human craniofacial morphology. However, the precise character of the prenatal ontogenetic development of the human cranium has yet to be fully establish...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00884.x
更新日期:2008-05-01 00:00:00
abstract::Whether the 1st segment of the human autopod 1st ray is a 'true' metapodial with loss of the proximal or mid phalanx or the original basal phalanx with loss of the metacarpal has been a long-lasting discussion. The actual knowledge of the developmental pattern of upper autopod segments at a fetal age of 20-22 weeks, c...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12883
更新日期:2018-12-01 00:00:00
abstract::The backbone or vertebral column is the defining feature of vertebrates and is clearly metameric. Given that vertebrae arise from segmented paraxial mesoderm in the embryo, this metamerism is not surprising. Fate mapping studies in a variety of species have shown that ventromedial sclerotome cells of the differentiate...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1046/j.1469-7580.2001.19910177.x
更新日期:2001-07-01 00:00:00
abstract::This review broadly summarizes how molecular biology has contributed to our understanding of human evolution. Molecular anthropology began in the 1960s with immunological comparisons indicating that African apes and humans were closely related and, indeed, shared a common ancestor as recently as 5 million years ago. A...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2007.00840.x
更新日期:2008-04-01 00:00:00
abstract::Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12677
更新日期:2017-12-01 00:00:00
abstract::Chromaffin cells were observed singly or in clusters in the heart and sympathetic cord of 2 genera of dipnoan fish, Protopterus and Lepidosiren. They were invariably found in close association with the autonomic sympathetic nervous system and at sites where chromaffin cells or their precursors are situated in mammals ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::The moment arm of a muscle represents its leverage or torque-producing capacity, and is indicative of the role of the muscle in joint actuation. The objective of this study was to undertake a systematic review of the moment arms of the major muscles spanning the glenohumeral joint during abduction, flexion and axial r...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12903
更新日期:2019-01-01 00:00:00
abstract::The effects of a chronic administration of angiotensin II on the zona fasciculata of rats treated with dexamethasone and maintenance doses of ACTH were investigated by morphometric methods applied to electron microscopy. It was found that angiotensin induced a significant increase in the volume of cells, nuclei, mitoc...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::The three kinds of keratinized epithelium evident on gross examination of the soft palate of Wistar albino rats were studied by scanning and transmission electron microscopy. Scanning indicated a central area where the epithelium showed numerous fine folds and papillae, more lateral areas which were smooth, and most l...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::There is evidence for lymphatic drainage of interstitial fluid from the brain along perivascular spaces in a number of mammalian species. Ultrastructural studies suggest that there are similar drainage pathways in the human cerebral cortex. Perivascular spaces in the basal ganglia, however, differ from those in the co...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19130337.x
更新日期:1997-10-01 00:00:00